Synthesis of antihyperglycemic, α-glucosidase inhibitory, and DPPH free radical scavenging furanochalcones

Medicinal Chemistry Research

Volumn 21, Issue 6, 2012, Pages 760-774

  Rao, R Ranga ^a   Tiwari, Ashok K ^a   Reddy, P Prabhakar ^a   Babu, K Suresh ^a   Suresh, G ^a   Ali, A Zehra ^a   Madhusudana, K ^a   Agawane, Sachin B ^a   Badrinarayan, Preethi ^a   Sastry, G Narahari ^a   Rao, J Madhusudana ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Glucosidase inhibitory activity; DPPH free radical scavenging activity; Furanochalcones; Molecular modeling; QSAR

Indexed keywords

1 (4 HYDROXYBENZOFURAN 5 YL) 3 (2,3,4 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 (4 HYDROXYBENZOFURAN 5 YL) 3 (4 HYDROXYPHENYL)PROP 2 EN 1 ONE; 1 (4 HYDROXYBENZOFURAN 5 YL) 3 (4 METHOXYPHENYL)PROP 2 EN 1 ONE; 1 (4 HYDROXYBENZOFURAN 5 YL) 3 PHENYLPROP 2 EN 1 ONE; 1 (6 HYDROXYBENZOFURAN 5 YL) 3 (2,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 (6 HYDROXYBENZOFURAN 5 YL) 3 (4 HYDROXYPHENYL)PROP 2 EN 1 ONE; 1 (6 HYDROXYBENZOFURAN 5 YL) 3 (4 METHOXYPHENYL)PROP 2 EN 1 ONE; 1 (6 HYDROXYBENZOFURAN 5 YL) 3 PHENYLPROP 2 EN 1 ONE; 1,1 DIPHENYL 2 PICRYLHYDRAZYL; 3 (3,4 DIHYDROXYPHENYL) 1 (4 HYDROXYBENZOFURAN 5 YL)PROP 2 EN 1 ONE; 3 (3,4 DIMETHOXYPHENYL) 1 (4 HYDROXYBENZOFURAN 5 YL)PROP 2 EN 1 ONE; 3 (3,4 DIMETHOXYPHENYL) 1 (6 HYDROXYBENZOFURAN 5 YL)PROP 2 EN 1 ONE; 3 (4 HYDROXY 3 METHOXYPHENYL) 1 (4 HYDROXYBENZOFURAN 5 YL)PROP 2 EN 1 ONE; 3 (4 HYDROXY 3 METHOXYPHENYL) 1 (6 HYDROXYBENZOFURAN 5 YL)PROP 2 EN 1 ONE; 3 [3,4 BIS(BENZYLOXY)PHENYL] 1 (4 HYDROXYBENZOFURAN 5 YL)PROP 2 EN 1 ONE; 3 [3,4 BIS(BENZYLOXY)PHENYL] 1 (6 HYDROXYBENZOFURAN 5 YL)PROP 2 EN 1 ONE; 3 [4 (BENZYLOXY) 3 METHOXYPHENYL] 1 (4 HYDROXYBENZOFURAN 5 YL)PROP 2 EN 1 ONE; 3 [4 (BENZYLOXY) 3 METHOXYPHENYL] 1 (6 HYDROXYBENZOFURAN 5 YL)PROP 2 EN 1 ONE; 3 [4 (BENZYLOXY)PHENYL] 1 (4 HYDROXYBENZOFURAN 5 YL)PROP 2 EN 1 ONE; 3 [4 (BENZYLOXY)PHENYL] 1 (6 HYDROXYBENZOFURAN 5 YL)PROP 2 EN 1 ONE; ACARBOSE; ALPHA GLUCOSIDASE; ALPHA GLUCOSIDASE INHIBITOR; ARGININE; ASPARTIC ACID; CHALCONE DERIVATIVE; FURANOCHALCONE DERIVATIVE; GLUTAMINE; TYROSINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; FEMALE; HYPERGLYCEMIA; MALE; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; STRUCTURE ACTIVITY RELATION;

EID: 84861864708     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-011-9583-7     Document Type: Article

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