Dolichandroside a, a new a-glucosidase inhibitor and dpph free-radical scavenger from dolichandrone falcata seem

Phytotherapy Research

Volumn 23, Issue 4, 2009, Pages 591-596

  Aparna, P ^a   Tiwari, Ashok K ^a   Srinivas, Pullela V ^a   Ali, A Zehra ^a   Anuradha, V ^a   Rao, J Madhusudana ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

A glucosidase inhibition; Dolichandrone falcata; Dolichandroside A; DPPH scavenging

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ACTEOSIDE; ALPHA GLUCOSIDASE INHIBITOR; DOLICHANDROSIDE A; FREE RADICAL; PLANT EXTRACT; SCAVENGER; UNCLASSIFIED DRUG; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; ALOESAPONARIN II; ALPHA GLUCOSIDASE; ANTHRAQUINONE DERIVATIVE; BIPHENYL DERIVATIVE; ENZYME INHIBITOR; GLUCOSIDE; GLYCOSIDE; PHENOL DERIVATIVE; PICRIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOLICHANDRONE FALCATA; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; MEDICINAL PLANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; SCAVENGING SYSTEM; BIGNONIACEAE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ISOLATION AND PURIFICATION; METABOLISM;

ALOE; DOLICHANDRONE;

ALPHA-GLUCOSIDASES; ANTHRAQUINONES; BIGNONIACEAE; BIPHENYL COMPOUNDS; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; GLUCOSIDES; GLYCOSIDES; MOLECULAR STRUCTURE; PHENOLS; PICRATES; PLANT EXTRACTS;

EID: 64549084589     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2672     Document Type: Article

References (19)

1. Andary C, Wylde R, Lafitte C, Privat G, Winternitz F. 1982. Structures of verbascoside and orobanchoside, caffeic acid sugar esters from Orobanche rapum-genistae. Phytochemistry21: 1123-1127.
2. Babu KS, Tiwari AK, Srinivas PV, Ali AZ, Raju BC, Rao JM. 2004. Yeast and mammalian a-glucosidase inhibitory constituents from Himalayan Rhubarb Rheum emodi Wall. Ex Meisson. Biorg Med Chem Lett 14: 3841-3845.
3. Baron AD. 1998. Postprandial hyperglycemia and a-glucosidase inhibitors. Diab Res Clin Pract 40: S51-S55.
4. Burnett AR, Thomson RH. 1967. Quinones.Part VIII. Dehydro-a- and β-lapachone. J Chem Soc C 1261-1264.
5. Chopra RN, Nayar SL, and Chopra IC. 1956. Glossary of Indian Medicinal Plants Vol.1. Council of Scientific and Industrial Research, New Delhi; 1: 100.
6. Delorme S, Chiasson J-L. 2005. Acarbose in the prevention of cardiovascular disease in subjects with impaired glucose tolerance and type 2 diabetes mellitus. Curr Opin Pharmacol 5: 184-189.
7. Dixit AM, Geevan CP. 2000. A quantitative analysis of plant use as a component of EIA: Case of Narmada Sagar hydroelectric project in central India. Curr Sci 79: 202-210.
8. Gafner ST, Wolfender JL, Niganga M, Stoeckli- Evans H, Hostettmann K. 1996. Antifungal and bacterial napthaquinones from Newbouldia leavis roots. Phytochemistry 42: 1315-1320.
9. Gedeon J, Kincl FA. 1956. Saponins and sapogeninsII. Arch Pharmacol 289: 162-165.
10. Hertzler S, Heacock P, Wolf B. 2005. Questioning the clinical significance of Salacia oblonga: Author's Response. J Am Diet Assoc 105: 1201-1202.
11. Kincl FA. 1955. Chrysine, the sapogenin of Dolichandrone falcata. Naturewissenschaften 42: 646.
12. Matsui T, Ogunwande IA, Abesundara KJM, Matsumoto K. 2006. Anti-hyperglycemic potential of natural products. Mini-Rev Med Chem 6: 109-120.
13. McCarty MF. 2000. Towards practical prevention of type 2 diabetes. Medical Hypotheses 65: 152-154.
14. McDougall GJ, Shpiro F, Dobson P, Smith P, Blake A, Stewart D. 2005. Different polyphenolic components of soft fruits inhibit a-amylase and a-glucosidase. J Agric Food Chem 53: 2760-2766.
15. Reddy SV, Tiwari AK, Kumar US, Rao JR, Rao JM. 2005. Free radical scavenging, enzyme inhibitory constituents from antidiabetic Ayurvedic medicinal plant Hydnocarpus wight- iana Blume. Phytother Res 19: 277-281.
16. Sastri BN. 1952. Wealth of India, Raw Materials Vol III. CSIR: New Delhi, India; 100.
17. Sies H, Stahl W, Sevanian A. 2005. Nutritional, dietary and postprandial oxidative stress. J Nutr 135: 969-972.
18. Subramanian SS, Nagarajan S, Sulochana N. 1972. Chrysin 7- rutinoside from the leaves of Dolichandrone falcata. Phytochemistry 11: 438-439.
19. Yamagishi S, Nakamura K, Takeuchi M. 2005. Inhibition of postprandial hyperglycemia by acarbose is a promising therapeutic strategy for the treatment of patients with the metabolic syndrome. Medical Hypotheses 65: 152-154.