α-Glucosidase inhibitory antihyperglycemic activity of substituted chromenone derivatives

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 1, 2010, Pages 358-365

  Raju, B China ^a   Tiwari, Ashok K ^a   Kumar, J Ashok ^a   Ali, A Zehra ^a   Agawane, Sachin B ^a   Saidachary, G ^a   Madhusudana, K ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Glucosidase inhibitory activity; Ketoesters; Antihyperglycemic activity; Boronic acids; DPPH scavenging activity; Piperidine; Salicylaldehydes; Substituted chromenone derivatives; Suzuki coupling

Indexed keywords

3 ACETYL 6 (3 PYRIDYL) 2H 2 CHROMENONE; 3 ACETYL 6 (4 CHLOROPHENYL) 2H 2 CHROMENONE; 3 ACETYL 6 (4 FLUOROPHENYL) 2H 2 CHROMENONE; 3 ACETYL 6 (4 METHYLPHENYL 2H 2 CHROMENONE; 3 ACETYL 6 (4 MORPHOLINOPHENYL) 2H 2 CHROMENONE; 3 ACETYL 6 (4 PYRIMIDINYL) 2H 2 CHROMENONE; 3 ACETYL 6 (6 METHOXY 3 PYRIDYL) 2H 2 CHROMENONE; 3 BENZOYL 2H 2 CHROMENONE; 3 BENZOYL 6 PHENYL 2H 2 CHROMENONE; 3 BENZOYL 7 HYDROXY 2H 2 CHROMENONE; 3 CHLORO 4 METHYL 7 HYDROXY 2H 2 CHROMENONE; 4 (CHLOROMETHYL) 7 HYDROXY 2H 2 CHROMENONE; 4 (CHLOROMETHYL) 7 HYDROXY 8 METHYL 2H 2 CHROMENONE; 4 METHYL 2 OXO 6 PHENYL 2H CHROMENE 3 CARBONITRILE; 6 (6 METHOXY 3 PYRIDYL) 4 METHYL 2 OXO 2H CHROMENE 3 CARBONITRILE; ALPHA GLUCOSIDASE; CHROMENE DERIVATIVE; ETHYL 2 OXO 6 (4 PYRIMIDINYL) 2H CHROMENE 3 CARBOXYLATE; ETHYL 6 (4 FLUOROPHENYL) 2 OXO 2H CHROMENE 3 CARBOXYLATE; ETHYL 6 (6 METHOXY 3 PYRIDYL) 2 OXO 2H CHROMENE 3 CARBOXYLATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; KNOEVENAGEL CONDENSATION; MALE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SUZUKI REACTION;

ALPHA-GLUCOSIDASES; ANIMALS; BENZOPYRANS; BIPHENYL COMPOUNDS; BLOOD GLUCOSE; FEMALE; FREE RADICAL SCAVENGERS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INTESTINES; MALE; PICRATES; RATS; RATS, WISTAR;

RATTUS; RATTUS NORVEGICUS;

EID: 72049090903     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.10.047     Document Type: Article

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