Treating colon cancer with a suicide gene delivered by self-assembled cationic MPEG-PCL micelles

Nanoscale

Volumn 4, Issue 7, 2012, Pages 2400-2407

  Duan, Xingmei ^a   Wang, Pan ^b   Men, Ke ^a   Gao, Xiang ^b   Huang, Meijuan ^a   Gou, Maling ^a   Chen, Lijuan ^a   Qian, Zhiyong ^a   Wei, Yuquan ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; CAPROLACTONE; CATIONIC MICELLES; COLON CANCER; COLON CANCER CELLS; GENE CARRIER; GENE DELIVERY; GOLD STANDARDS; HYBRID MICELLE; IN-VITRO; IN-VIVO; INTRAPERITONEAL ADMINISTRATION; MEAN PARTICLE SIZE; MONOMETHOXY POLY(ETHYLENE GLYCOL); ONE STEP; SELF-ASSEMBLED; TRANSFECTION EFFICIENCY;

CELL DEATH; DISEASES; GENE TRANSFER; GENES; MOTION PICTURE EXPERTS GROUP STANDARDS; POLYETHYLENE GLYCOLS; ZETA POTENTIAL;

MICELLES;

MACROGOL DERIVATIVE; METHOXY POLY(ETHYLENE GLYCOL CO EPSILON CAPROLACTONE); METHOXY POLY(ETHYLENE GLYCOL-CO-EPSILON-CAPROLACTONE); POLYESTER;

ADENOCARCINOMA; ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BIOLOGICAL MODEL; CHEMISTRY; COLON TUMOR; DRUG DELIVERY SYSTEM; EVALUATION; FEMALE; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; INSTRUMENTATION; METHODOLOGY; MICELLE; MOUSE; SUICIDE TRANSGENE; TUMOR CELL LINE;

ADENOCARCINOMA; ANIMALS; CELL LINE, TUMOR; COLONIC NEOPLASMS; DRUG DELIVERY SYSTEMS; FEMALE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENES, TRANSGENIC, SUICIDE; GENETIC VECTORS; MICE; MICE, INBRED BALB C; MICELLES; MODELS, BIOLOGICAL; POLYESTERS; POLYETHYLENE GLYCOLS; TRANSFECTION;

EID: 84861850937     PISSN: 20403364     EISSN: 20403372     Source Type: Journal    
DOI: 10.1039/c2nr30079f     Document Type: Article

References (43)

1. A. Jemal F. Bray M. M. Center J. Ferlay E. Ward D. Forman Global cancer statistics Ca-Cancer J. Clin. 2011 61 69 90
2. L. Ricci-Vitiani D. G. Lombardi E. Pilozzi M. Biffoni M. Todaro C. Peschle R. De Maria Identification and expansion of human colon-cancer- initiating cells Nature 2006 445 111 115
3. R. A. Morgan M. E. Dudley J. R. Wunderlich M. S. Hughes J. C. Yang R. M. Sherry R. E. Royal S. L. Topalian U. S. Kammula N. P. Restifo et al., Cancer regression in patients after transfer of genetically engineered lymphocytes Science 2006 314 126 129
4. I. M. Verma N. Somia Gene therapy - promises, problems and prospects Nature 1997 389 239 242
5. J. R. Aspe N. R. Wall Survivin-T34A: molecular mechanism and therapeutic potential OncoTargets Ther. 2010 3 247 254
6. C. Bonini A. Bondanza S. K. Perna S. Kaneko C. Traversari F. Ciceri C. Bordignon The suicide gene therapy challenge: how to improve a successful gene therapy approach Mol. Ther. 2007 15 1248 1252
7. Y. H. Huang G. T. Zugates W. Peng D. Holtz C. Dunton J. J. Green N. Hossain M. R. Chernick R. F. PaderaJr. R. Langer et al., Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice Cancer Res. 2009 69 6184 6191
8. D. J. Glover H. J. Lipps D. A. Jans Towards safe, non-viral therapeutic gene expression in humans Nat. Rev. Genet. 2005 6 299 310
9. C. E. Thomas A. Ehrhardt M. A. Kay Progress and problems with the use of viral vectors for gene therapy Nat. Rev. Genet. 2003 4 346 358
10. R. J. Yanez-Munoz K. S. Balaggan A. MacNeil S. J. Howe M. Schmidt A. J. Smith P. Buch R. E. MacLaren P. N. Anderson S. E. Barker et al., Effective gene therapy with nonintegrating lentiviral vectors Nat. Med. 2006 12 348 353
11. M. A. Kay J. C. Glorioso L. Naldini Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics Nat. Med. 2001 7 33 40
12. L. Thomas A non-viral vector for in vivo gene delivery Lancet Neurol. 2005 4 602
13. J. A. Hubbell Non-viral gene delivery: multifunctional polyplexes as locally triggerable nonviral vectors Gene Ther. 2006 13 1371 1372
14. M. E. Davis Z. G. Chen D. M. Shin Nanoparticle therapeutics: an emerging treatment modality for cancer Nat. Rev. Drug Discovery 2008 7 771 782
15. D. Schaffert E. Wagner Gene therapy progress and prospects: synthetic polymer-based systems Gene Ther. 2008 15 1131 1138
16. L. De Laporte J. Cruz Rea L. D. Shea Design of modular non-viral gene therapy vectors Biomaterials 2006 27 947 954
17. M. Ferrari Cancer nanotechnology: opportunities and challenges Nat. Rev. Cancer 2005 5 161 171
18. G. F. Liang Y. L. Zhu B. Sun F. H. Hu T. Tian S. C. Li Z. D. Xiao PLGA-based gene delivering nanoparticle enhance suppression effect of miRNA in HePG2 cells Nanoscale Res. Lett. 2011 6 447
19. J. S. Park H. N. Yang D. G. Woo S. Y. Jeon H. J. Do H. Y. Lim J. H. Kim K. H. Park Chondrogenesis of human mesenchymal stem cells mediated by the combination of SOX trio SOX5, 6, and 9 genes complexed with PEI-modified PLGA nanoparticles Biomaterials 2011 32 3679 3688
20. T. K. Endres M. Beck-Broichsitter O. Samsonova T. Renette T. H. Kissel Self-assembled biodegradable amphiphilic PEG-PCL-lPEI triblock copolymers at the borderline between micelles and nanoparticles designed for drug and gene delivery Biomaterials 2011 32 7721 7731
21. S. Y. Kim Y. M. Lee D. J. Baik J. S. Kang Toxic characteristics of methoxy poly(ethylene glycol)/poly(epsilon-caprolactone) nanospheres; in vitro and in vivo studies in the normal mice Biomaterials 2003 24 55 63
22. Y. Hu L. Zhang Y. Cao H. Ge X. Jiang C. Yang Degradation behavior of poly(epsilon-caprolactone)-b-poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles in aqueous solution Biomacromolecules 2004 5 1756 1762
23. M. Gou X. Wei K. Men B. Wang F. Luo X. Zhao Y. Wei Z. Qian PCL/PEG copolymeric nanoparticles: potential nanoplatforms for anticancer agent delivery Curr. Drug Targets 2011 12 1131 1150
24. K. Tanaka T. Kanazawa Y. Shibata Y. Suda T. Fukuda Y. Takashima H. Okada Development of cell-penetrating peptide-modified MPEG-PCL diblock copolymeric nanoparticles for systemic gene delivery Int. J. Pharm. 2010 396 229 238
25. Y. Liu O. Samsonova B. Sproat O. Merkel T. Kissel Biophysical characterization of hyper-branched polyethylenimine-graft-polycaprolactone- block-mono-methoxyl-poly(ethylene glycol) copolymers (hy-PEI-PCL-mPEG) for siRNA delivery J. Controlled Release 2011 153 262 268
26. M. Gou X. Zheng K. Men J. Zhang B. Wang L. Lv X. Wang Y. Zhao F. Luo L. Chen et al., Self-assembled hydrophobic honokiol loaded MPEG-PCL diblock copolymer micelles Pharm. Res. 2009 26 2164 2173
27. M. Gou K. Men H. Shi M. Xiang J. Zhang J. Song J. Long Y. Wan F. Luo X. Zhao Z. Qian Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo Nanoscale 2011 3 1558 1567
28. M. Gou H. Shi G. Guo K. Men J. Zhang L. Zheng Z. Li F. Luo Z. Qian X. Zhao Y. Wei Improving anticancer activity and reducing systemic toxicity of doxorubicin by self-assembled polymeric micelles Nanotechnology 2011 22 095102
29. L. Zhang X. Gao K. Men B. Wang S. Zhang J. Qiu M. Huang M. Gou N. Huang Z. Qian et al., Gene therapy for C-26 colon cancer using heparin- polyethyleneimine nanoparticle-mediated survivin T34A Int. J. Nanomedicine 6 2419 2427
30. E. Marshall Gene therapy death prompts review of adenovirus vector Science 1999 286 2244 2245
31. D. Simberg S. Weisman Y. Talmon Y. Barenholz DOTAP (and other cationic lipids): chemistry, biophysics, and transfection Crit. Rev. Ther. Drug Carrier Syst. 2004 21 257 317
32. W. Zhao A. A. Gurtovenko I. Vattulainen M. Karttunen Cationic DMPC/DOTAP Lipid Bilayers: Atomistic Insight for Structure and Dynamics J. Phys. Chem. B 2011
33. B. Gopalan I. Ito C. D. Branch C. Stephens J. A. Roth R. Ramesh Nanoparticle based systemic gene therapy for lung cancer: molecular mechanisms and strategies to suppress nanoparticle-mediated inflammatory response Technol. Cancer Res. Treat. 2004 3 647 657
34. G. N. Hortobagyi N. T. Ueno W. Xia S. Zhang J. K. Wolf J. B. Putnam P. L. Weiden J. S. Willey M. Carey D. L. Branham et al., Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial J. Clin. Oncol. 2001 19 3422 3433
35. M. Singh M. Briones G. Ott D. O'Hagan Cationic microparticles: A potent delivery system for DNA vaccines Proc. Natl. Acad. Sci. U. S. A. 2000 97 811 816
36. D. Hanahan R. A. Weinberg Hallmarks of cancer: the next generation Cell 2011 144 646 674
37. A. C. Mita M. M. Mita S. T. Nawrocki F. J. Giles Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics Clin. Cancer Res. 2008 14 5000 5005
38. N. Zaffaroni M. Pennati M. G. Daidone Survivin as a target for new anticancer interventions J. Cell. Mol. Med. 2005 9 360 372
39. S. K. Chiou M. K. Jones A. S. Tarnawski Survivin-an anti-apoptosis protein: its biological roles and implications for cancer and beyond Med. Sci. Monit. 2003 9 PI25 29
40. D. S. O'Connor D. Grossman J. Plescia F. Li H. Zhang A. Villa S. Tognin P. C. Marchisio D. C. Altieri Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin Proc. Natl. Acad. Sci. U. S. A. 2000 97 13103 13107
41. M. Mesri N. R. Wall J. Li R. W. Kim D. C. Altieri Cancer gene therapy using a survivin mutant adenovirus J. Clin. Invest. 2001 108 981 990
42. H. X. Li X. Y. Zhao L. Wang Y. S. Wang B. Kan J. R. Xu J. Li Y. J. Wen X. C. Peng X. Chen et al., Antitumor effect of mSurvivinThr34->Ala in murine colon carcinoma when administered intravenously Med. Pediatr. Oncol. 2009 27 1156 1163
43. D. Grossman P. J. Kim J. S. Schechner D. C. Altieri Inhibition of melanoma tumor growth in vivo by survivin targeting Proc. Natl. Acad. Sci. U. S. A. 2001 98 635 640