Elimination of specific miRNAs by naked 14-nt sgRNAs

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Takahashi, Masayuki ^a   Elbarbary, Reyad A ^a   Abe, Mayumi ^a   Sato, Mari ^b   Yoshida, Tetsuo ^c   Yamada, Yoji ^c   Tamura, Masato ^b   Nashimoto, Masayuki ^a  

^a NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 16; MIR 142 3P; MIR 19A; MIR 19B; MIR 206; PROTEIN SGRNA; SMALL GUIDE RNA; TRANSFER RNA; TRNASE ZL; UNCLASSIFIED DRUG; GUIDE RNA; MIRN16 MICRORNA, HUMAN; NUCLEOTIDE; RIBONUCLEASE; TRNASE Z, HUMAN;

ARTICLE; CELL STRAIN HEK293; CELL STRAIN HL 60; CONTROLLED STUDY; DOWN REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MAMMAL CELL; RNA ANALYSIS; RNA CLEAVAGE; RNA SYNTHESIS; CELL LINE; CELL SURVIVAL; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

MAMMALIA;

BASE SEQUENCE; CELL LINE; CELL SURVIVAL; DOWN-REGULATION; ENDORIBONUCLEASES; GENE SILENCING; HUMANS; MICRORNAS; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; RNA, GUIDE;

EID: 84861849684     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038496     Document Type: Article

References (30)

1. Nashimoto M, (1997) Distribution of both lengths and 5′ terminal nucleotides of mammalian pre-tRNA 3′ trailers reflects properties of 3′ processing endoribonuclease. Nucleic Acids Res 25: 1148-1155.
2. Takaku H, Minagawa A, Masamichi T, Nashimoto M, (2003) A candidate prostate cancer susceptibility gene encodes tRNA 3′ processing endoriobonuclease. Nucleic Acids Res 31: 2272-2278.
3. Elbarbary RA, Takaku H, Uchiumi N, Tamiya H, Abe M, et al. (2009) Modulation of gene expression by human cytosolic tRNase ZL through 5′-half-tRNA. PLoS ONE 4: e5908.
4. Elbarbary RA, Takaku H, Uchiumi N, Tamiya H, Abe M, et al. (2009) Human cytosolic tRNase ZL can downregulate gene expression through miRNA. FEBS Lett 583: 3241-3246.
5. Tamura M, Nashimoto C, Miyake N, Daikuhara Y, Ochi K, et al. (2003) Intracellular mRNA cleavage by 3′ tRNase under the direction of 2′-O-methyl RNA heptamers. Nucleic Acids Res 31: 4354-4360.
6. Habu Y, Miyano-Kurosaki N, Kitano M, Endo Y, Yukita M, et al. (2005) Inhibition of HIV-1 gene expression by retroviral vector-mediated small-guide RNAs that direct specific RNA cleavage by tRNase ZL. Nucleic Acids Res 33: 235-243.
7. Nakashima A, Takaku H, Shibata HS, Negishi Y, Takagi M, et al. (2007) Gene-silencing by the tRNA maturase tRNase ZL under the direction of small guide RNA. Gene Therapy 14: 78-85.
8. Elbarbary RA, Takaku H, Tamura M, Nashimoto M, (2009) Inhibition of vascular endothelial growth factor expression by TRUE gene silencing. Biochem and Biophys Res Commun 379: 924-927.
9. Sano T, Takahashi M, Nozaki T, Takahashi Y, Tamura M, et al. (2011) Expanding the utility of heptamer-type sgRNA for TRUE gene silencing. Biochem and Biophys Res Commun 416: 427-432.
10. Nashimoto M, (1995) Conversion of mammalian tRNA 3′ processing endoribonuclease to four-base-recognizing RNA cutters. Nucleic Acids Res 23: 3642-3647.
11. Nashimoto M, (1996) Specific cleavage of target RNAs from HIV-1 with 5′ half tRNA by mammalian tRNA 3′ processing endoribonuclease. RNA 2: 2523-2524.
12. Nashimoto M, Geary S, Tamura M, Kasper R, (1998) RNA heptamers that directs RNA cleavage by mammalian tRNA 3′ processing endoribonuclease. Nucleic Acids Res 26: 2565-2571.
13. Nashimoto M, (2000) Anomalous RNA substrates for mammalian tRNA 3′ processing endoribonuclease. FEBS Lett 472: 179-186.
14. Takaku H, Minagawa A, Takagi M, Nashimoto M, (2004) The N-terminal half-domain of the long form of tRNase Z is required for the RNase 65 activity. Nucleic Acids Res 32: 4429-4438.
15. Takaku H, Minagawa A, Takagi M, Nashimoto M, (2004) A novel four-base-recognizing RNA cutter that can remove the single 3′ terminal nucleotides from RNA molecules. Nucleic Acids Res 32: e91.
16. Shibata HS, Takaku H, Takagi M, Nashimoto M, (2005) The T loop structure is dispensable for substrate recognition by tRNase ZL. J Biol Chem 280: 22326-22334.
17. Sayed D, Abdellatif M, (2011) MicroRNAs in development and disease. Physiol Rev 91: 827-887.
18. Aqeilan RI, Calin GA, Croce CM, (2010) miR-15a and miR-16-1 in cancer: discovery, function and future perspectives. Cell Death Differ 17: 215-220.
19. Cho WC, (2007) OncomiRs: the discovery and progress of microRNAs in cancers. Mol Cancer 6: 60.
20. Pichiorri F, Suh SS, Ladetto M, Kuehl M, Palumbo T, et al. (2008) MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis. Proc Natl Acad Sci USA 105: 12885-12890.
21. Elmén J, Lindow M, Schütz S, Lawrence M, Petri A, et al. (2008) LNA-mediated microRNA silencing in non-human primates. Nature 452: 896-899.
22. Lanford RE, Hildebrandt-Eriksen ES, Petri A, Persson R, Lindow M, et al. (2010) Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327: 198-201.
23. Graham FL, Smiley J, Russell WC, Nairn R, (1977) Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol 36: 59-74.
24. Scherer WF, Syverton JT, Gey GO, (1953) Studies on the propagation in vitro of poliomyelitis viruses. IV. Viral multiplication in a stable strain of human malignant epithelial cells (strain HeLa) derived from an epidermoid carcinoma of the cervix. J Exp Med 97: 695-710.
25. Schneider U, Schwenk H, Bornkamm G, (1977) Characterization of EBV-genome negative "null" and "T" cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma Int J Cancer 19: 621-626.
26. Gallagher R, Collins S, Trujillo J, McCredie K, Ahearn M, et al. (1979) Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia. Blood 54: 713-733.
27. Yaffe D, Saxel O, (1977) Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle. Nature 270: 725-727.
28. Matsuoka Y, Moore GE, Yagi Y, Pressman D, (1967) Production of free light chains of immunoglobulin by a hematopoietic cell line derived from a patient with multiple myeloma. Proc Soc Exp Biol Med 125: 1246-1250.
29. Nashimoto M, Tamura M, Kaspar RL, (1999) Selection of cleavage site by mammalian tRNA 3′ processing endoribonuclease. J Mol Biol 287: 727-740.
30. Cimmino A, Calin GA, Fabbri M, Iorio MV, Ferracin M, et al. (2005) miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 102: 13944-13949.