Expanding the utility of heptamer-type sgRNA for TRUE gene silencing

Biochemical and Biophysical Research Communications

Volumn 416, Issue 3-4, 2011, Pages 427-432

  Sano, Takako ^a   Takahashi, Masayuki ^a   Nozaki, Tadasuke ^a   Takahashi, Yoshiaki ^b   Tamura, Masato ^c   Nashimoto, Masayuki ^a  

^a NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Heptamer; Locked nucleic acid; SgRNA; TRNase Z L; TRUE gene silencing

Indexed keywords

HEPTAMER; LOCKED NUCLEIC ACID; POLYMER; RECOMBINANT PROTEIN; RNA; SMALL GUIDE RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER GENE THERAPY; CELL STRAIN HEK293; EMBRYO; GENE SILENCING; GENETIC ENGINEERING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL LINE; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN MODIFICATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA CLEAVAGE; RNA SYNTHESIS; TRNASE ZL UTILIZING EFFICACIOUS GENE SILENCING;

ENDORIBONUCLEASES; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HEK293 CELLS; HUMANS; JURKAT CELLS; OLIGONUCLEOTIDES; RNA CLEAVAGE; RNA, GUIDE; RNA, SMALL INTERFERING;

MAMMALIA;

EID: 84855881310     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.11.091     Document Type: Article

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