-
1
-
-
0029953780
-
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family
-
DOI 10.1016/S0092-8674(00)81267-2
-
Kipreos ET, Lander LE, Wing JP, et al. CUL-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Cell 1996;85:829-39. (Pubitemid 26192134)
-
(1996)
Cell
, vol.85
, Issue.6
, pp. 829-839
-
-
Kipreos, E.T.1
Lander, L.E.2
Wing, J.P.3
He, W.W.4
Hedgecock, E.M.5
-
2
-
-
0037967230
-
CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing
-
DOI 10.1038/nature01747
-
Zhong W, Feng H, Santiago FE, et al. CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing. Nature 2003;423:885-9. (Pubitemid 36781282)
-
(2003)
Nature
, vol.423
, Issue.6942
, pp. 885-889
-
-
Zhong, W.1
Feng, H.2
Santiago, F.E.3
Kipreos, E.T.4
-
3
-
-
0037133036
-
The Caenorhabditis elegans Skp1-related gene family: Diverse functions in cell proliferation, morphogenesis, and meiosis
-
DOI 10.1016/S0960-9822(02)00682-6, PII S0960982202006826
-
Nayak S, Santiago FE, Jin H, et al. The Caenorhabditis elegans Skp1-related gene family: diverse functions in cell proliferation, morphogenesis, and meiosis. Curr Biol 2002;12:277-87. (Pubitemid 34161471)
-
(2002)
Current Biology
, vol.12
, Issue.4
, pp. 277-287
-
-
Nayak, S.1
Santiago, F.E.2
Jin, H.3
Lin, D.4
Schedl, T.5
Kipreos, E.T.6
-
4
-
-
36749104190
-
Cdt1 degradation to prevent DNA re-replication: Conserved and non-conserved pathways
-
Kim Y, Kipreos ET. Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways. Cell Div 2007;2:18.
-
(2007)
Cell Div
, vol.2
, pp. 18
-
-
Kim, Y.1
Kipreos, E.T.2
-
5
-
-
33846916845
-
The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex
-
DOI 10.1128/MCB.00736-06
-
Kim Y, Kipreos ET. The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex. Mol Cell Biol 2007;27:1394-406. (Pubitemid 46239821)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.4
, pp. 1394-1406
-
-
Kim, Y.1
Kipreos, E.T.2
-
6
-
-
77956406531
-
C. elegans CAND-1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissues
-
Bosu DR, Feng H, Min K, et al. C. elegans CAND-1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissues. Dev Biol 2010;346:113-26.
-
(2010)
Dev Biol
, vol.346
, pp. 113-126
-
-
Bosu, D.R.1
Feng, H.2
Min, K.3
-
7
-
-
33747823839
-
L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes
-
Banks D, Wu M, Higa LA, et al. L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes. Cell Cycle 2006;5:1719-29. (Pubitemid 44285260)
-
(2006)
Cell Cycle
, vol.5
, Issue.15
, pp. 1719-1729
-
-
Banks, D.1
Wu, M.2
Higa, L.A.3
Gavrilova, N.4
Quan, J.5
Ye, T.6
Kobayashi, R.7
Sun, H.8
Zhang, H.9
-
8
-
-
36248975284
-
Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication
-
DOI 10.1101/gad.1586007
-
Aggarwal P, Lessie MD, Lin DI, et al. Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes Dev 2007;21:2908-22. (Pubitemid 350133439)
-
(2007)
Genes and Development
, vol.21
, Issue.22
, pp. 2908-2922
-
-
Aggarwal, P.1
Lessie, M.D.2
Lin, D.I.3
Pontano, L.4
Gladden, A.B.5
Nuskey, B.6
Goradia, A.7
Wasik, M.A.8
Klein-Szanto, A.J.P.9
Rustgi, A.K.10
Bassing, C.H.11
Diehl, J.A.12
-
9
-
-
57049133181
-
CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation
-
Nishitani H, Shiomi Y, Iida H, et al. CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation. J Biol Chem 2008;283:29045-52.
-
(2008)
J Biol Chem
, vol.283
, pp. 29045-29052
-
-
Nishitani, H.1
Shiomi, Y.2
Iida, H.3
-
10
-
-
0028870394
-
Genomic instability and the role of p53 mutations in cancer cells
-
Smith ML, Fornace AJ Jr. Genomic instability and the role of p53 mutations in cancer cells. Curr Opin Oncol 1995;7:69-75.
-
(1995)
Curr Opin Oncol
, vol.7
, pp. 69-75
-
-
Smith, M.L.1
Fornace Jr., A.J.2
-
11
-
-
78650308849
-
Understanding wild-type and mutant p53 activities in human cancer: New landmarks on the way to targeted therapies
-
Goldstein I, Marcel V, Olivier M, et al. Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies. Cancer Gene Ther 2011;18:2-11.
-
(2011)
Cancer Gene Ther
, vol.18
, pp. 2-11
-
-
Goldstein, I.1
Marcel, V.2
Olivier, M.3
-
12
-
-
0028352434
-
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
-
DOI 10.1038/369574a0
-
Waga S, Hannon GJ, Beach D, et al. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 1994;369:574-8. (Pubitemid 24192528)
-
(1994)
Nature
, vol.369
, Issue.6481
, pp. 574-578
-
-
Waga, S.1
Hannon, G.J.2
Beach, D.3
Stillman, B.4
-
13
-
-
77951985216
-
Examination of the expanding pathways for the regulation of p21 expression and activity
-
Jung YS, Qian Y, Chen X. Examination of the expanding pathways for the regulation of p21 expression and activity. Cell Signal 2010;22:1003-12.
-
(2010)
Cell Signal
, vol.22
, pp. 1003-1012
-
-
Jung, Y.S.1
Qian, Y.2
Chen, X.3
-
14
-
-
0037042177
-
Waf1/Cip1/Sdi1: Association with cell senescence and tumour-promoting activities of stromal fibroblasts
-
DOI 10.1016/S0304-3835(01)00847-3, PII S0304383501008473
-
Roninson IB. Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts. Cancer Lett 2002;179:1-14. (Pubitemid 34195647)
-
(2002)
Cancer Letters
, vol.179
, Issue.1
, pp. 1-14
-
-
Roninson, I.B.1
-
15
-
-
19344376176
-
Chromosomal instability in mouse metastatic pancreatic cancer - It's Kras and Tp53 after all
-
DOI 10.1016/j.ccr.2005.04.025, PII S1535610805001303
-
Siveke JT, Schmid RM. Chromosomal instability in mouse metastatic pancreatic cancerd - it's Kras and Tp53 after all. Cancer Cell 2005;7:405-7. (Pubitemid 40719123)
-
(2005)
Cancer Cell
, vol.7
, Issue.5
, pp. 405-407
-
-
Siveke, J.T.1
Schmid, R.M.2
-
16
-
-
67649424560
-
P21 in cancer: Intricate networks and multiple activities
-
Abbas T, Dutta A. P21 in cancer: intricate networks and multiple activities. Nat Rev Cancer 2009;9:400-14.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 400-414
-
-
Abbas, T.1
Dutta, A.2
-
17
-
-
51949112601
-
The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing
-
Kim Y, Starostina NG, Kipreos ET. The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing. Genes Dev 2008;22:2507-19.
-
(2008)
Genes Dev
, vol.22
, pp. 2507-2519
-
-
Kim, Y.1
Starostina, N.G.2
Kipreos, E.T.3
-
18
-
-
51949098691
-
PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex
-
Abbas T, Sivaprasad U, Terai K, et al. PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. Genes Dev 2008;22:2496-506.
-
(2008)
Genes Dev
, vol.22
, pp. 2496-2506
-
-
Abbas, T.1
Sivaprasad, U.2
Terai, K.3
-
19
-
-
0032529631
-
The human homologue for the Caenorhabditis elegans cul-4 gene is amplified and overexpressed in primary breast cancers
-
Chen LC, Manjeshwar S, Lu Y, et al. The human homologue for the Caenorhabditis elegans CUL-4 gene is amplified and overexpressed in primary breast cancers. Cancer Res 1998;58:3677-83. (Pubitemid 28376568)
-
(1998)
Cancer Research
, vol.58
, Issue.16
, pp. 3677-3683
-
-
Chen, L.-C.1
Manjeshwar, S.2
Lu, Y.3
Moore, D.4
Ljung, B.-M.5
Kuo, W.-L.6
Dairkee, S.H.7
Wernick, M.8
Collins, C.9
Smith, H.S.10
-
20
-
-
34247159720
-
Overexpression of the human homologue for Caenorhabditis elegans cul-4 gene is associated with poor outcome in node-negative breast cancer
-
Schindl M, Gnant M, Schoppmann SF, et al. Overexpression of the human homologue for Caenorhabditis elegans CUL-4 gene is associated with poor outcome in node-negative breast cancer. Anticancer Res 2007;27:949-52. (Pubitemid 46587004)
-
(2007)
Anticancer Research
, vol.27
, Issue.2
, pp. 949-952
-
-
Schindl, M.1
Gnant, M.2
Schoppmann, S.F.3
Horvat, R.4
Birner, P.5
-
21
-
-
0034896068
-
Expression of hypoxia-inducible factor 1alpha in epithelial ovarian tumors: Its impact on prognosis and on response to chemotherapy
-
Birner P, Schindl M, Obermair A, et al. Expression of hypoxia-inducible factor 1alpha in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy. Clin Cancer Res 2001;7:1661-8. (Pubitemid 32708633)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.6
, pp. 1661-1668
-
-
Birner, P.1
Schindl, M.2
Obermair, A.3
Breitenecker, G.4
Oberhuber, G.5
-
22
-
-
0037316988
-
Level of Id-1 protein expression correlates with poor differentiation, enhanced malignant potential, and more aggressive clinical behavior of epithelial ovarian tumors
-
Schindl M, Schoppmann SF, Strobel T, et al. Level of Id-1 protein expression correlates with poor differentiation, enhanced malignant potential, and more aggressive clinical behavior of epithelial ovarian tumors. Clin Cancer Res 2003;9:779-85. (Pubitemid 36182615)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.2
, pp. 779-785
-
-
Schindl, M.1
Schoppmann, S.F.2
Strobel, T.3
Heinzl, H.4
Leisser, C.5
Horvat, R.6
Birner, P.7
-
23
-
-
0034098827
-
Staining patterns of p53 immunohistochemistry and their biological significance in colorectal cancer
-
DOI 10.1002/(SICI)1096-9896(200003)190:4<450::AID-PATH545>3.0.CO;2- 8
-
Kaserer K, Schmaus J, Bethge U, et al. Staining patterns of p53 immunohistochemistry and their biological significance in colorectal cancer. J Pathol 2000;190:450-6. (Pubitemid 30163585)
-
(2000)
Journal of Pathology
, vol.190
, Issue.4
, pp. 450-456
-
-
Kaserer, K.1
Schmaus, J.2
Bethge, U.3
Migschitz, B.4
Fasching, S.5
Walch, A.6
Herbst, F.7
Teleky, B.8
Wrba, F.9
-
24
-
-
0034282518
-
Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer
-
Birner P, Schindl M, Obermair A, et al. Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res 2000;60:4693-6.
-
(2000)
Cancer Res
, vol.60
, pp. 4693-4696
-
-
Birner, P.1
Schindl, M.2
Obermair, A.3
-
25
-
-
2342642220
-
Preventing DNA re-replication - Divergent safeguards in yeast and metazoa
-
Feng H, Kipreos ET. Preventing DNA re-replication - divergent safeguards in yeast and metazoa. Cell Cycle 2003;2:431-4.
-
(2003)
Cell Cycle
, vol.2
, pp. 431-434
-
-
Feng, H.1
Kipreos, E.T.2
-
26
-
-
0033756308
-
Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: Assembly of prereplication complexes in late mitosis
-
Mendez J, Stillman B. Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis. Mol Cell Biol 2000;20:8602-12.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8602-8612
-
-
Mendez, J.1
Stillman, B.2
-
27
-
-
33645309411
-
Involvement of CUL4 ubiquitin E3 ligases in regulating CDK inhibitors Dacapo/p27Kip1 and cyclin e degradation
-
Higa LA, Yang X, Zheng J, et al. Involvement of CUL4 ubiquitin E3 ligases in regulating CDK inhibitors Dacapo/p27Kip1 and cyclin E degradation. Cell Cycle 2006;5:71-7.
-
(2006)
Cell Cycle
, vol.5
, pp. 71-77
-
-
Higa, L.A.1
Yang, X.2
Zheng, J.3
-
28
-
-
34249674950
-
C. elegans CUL-4 Prevents Rereplication by Promoting the Nuclear Export of CDC-6 via a CKI-1-Dependent Pathway
-
DOI 10.1016/j.cub.2007.04.055, PII S0960982207013358
-
Kim J, Feng H, Kipreos ET. C. elegans CUL-4 prevents rereplication by promoting the nuclear export of CDC-6 via a CKI-1-dependent pathway. Curr Biol 2007;17:966-72. (Pubitemid 46829838)
-
(2007)
Current Biology
, vol.17
, Issue.11
, pp. 966-972
-
-
Kim, J.1
Feng, H.2
Kipreos, E.T.3
-
29
-
-
0842287638
-
DNA damage tumor suppressor genes and genomic instability
-
DOI 10.1016/j.gde.2003.12.003
-
Motoyama N, Naka K. DNA damage tumor suppressor genes and genomic instability. Curr Opin Genet Dev 2004;14:11-16. (Pubitemid 38173005)
-
(2004)
Current Opinion in Genetics and Development
, vol.14
, Issue.1
, pp. 11-16
-
-
Motoyama, N.1
Naka, K.2
-
30
-
-
67649342589
-
Ionizing radiation induces ATM-independent degradation of p21Cip1 in transformed cells
-
Stuart SA, Wang JY. Ionizing radiation induces ATM-independent degradation of p21Cip1 in transformed cells. J Biol Chem 2009;284:15061-70.
-
(2009)
J Biol Chem
, vol.284
, pp. 15061-15070
-
-
Stuart, S.A.1
Wang, J.Y.2
-
31
-
-
0028988585
-
Inhibitors of mammalian G1 cyclin-dependent kinases
-
Sherr CJ, Roberts JM. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 1995;9:1149-63.
-
(1995)
Genes Dev
, vol.9
, pp. 1149-1163
-
-
Sherr, C.J.1
Roberts, J.M.2
|