메뉴 건너뛰기




Volumn 122, Issue 6, 2012, Pages 2289-2300

Glutathione deficiency in type 2 diabetes impairs cytokine responses and control of intracellular bacteria

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; GAMMA INTERFERON; GLUTATHIONE; INTERLEUKIN 12P70; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5;

EID: 84861833415     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI57817     Document Type: Article
Times cited : (81)

References (52)
  • 1
    • 71549126811 scopus 로고    scopus 로고
    • Tuberculosis and diabetes mellitus: Convergence of two epidemics
    • Dooley KE, Chaisson RE. Tuberculosis and diabetes mellitus: convergence of two epidemics. Lancet Infect Dis. 2009;9(12):737-746.
    • (2009) Lancet Infect Dis , vol.9 , Issue.12 , pp. 737-746
    • Dooley, K.E.1    Chaisson, R.E.2
  • 2
    • 0033533807 scopus 로고    scopus 로고
    • Nephropathy in patients with type 2 diabetes mellitus
    • DOI 10.1056/NEJM199910073411506
    • Ritz E, Orth SR. Nephropathy in patients with type 2 diabetes mellitus. N Engl J Med. 1999;341(15):1127-1133. (Pubitemid 29466226)
    • (1999) New England Journal of Medicine , vol.341 , Issue.15 , pp. 1127-1133
    • Ritz, E.1    Orth, S.R.2
  • 3
    • 33646098696 scopus 로고    scopus 로고
    • Role of diabetes in atherosclerotic pathogenesis. What have we learned from animal models?
    • Renard C, Van Obberghen E. Role of diabetes in atherosclerotic pathogenesis. What have we learned from animal models? Diabetes Metab. 2006;32(1):15-29. (Pubitemid 43872592)
    • (2006) Diabetes and Metabolism , vol.32 , Issue.1 , pp. 15-29
    • Renard, C.1    Van Obberghen, E.2
  • 6
    • 0026782227 scopus 로고
    • Impaired immune responses in diabetes mellitus: Analysis of the factors and mechanisms involved. Relevance to the increased susceptibility of diabetic patients to specific infections
    • Moutschen MP, Scheen AJ, Lefebvre PJ. Impaired immune responses in diabetes mellitus: analysis of the factors and mechanisms involved. Relevance to the increased susceptibility of diabetic patients to specific infections. Diabetes Metab. 1992;18(3):187-201.
    • (1992) Diabetes Metab , vol.18 , Issue.3 , pp. 187-201
    • Moutschen, M.P.1    Scheen, A.J.2    Lefebvre, P.J.3
  • 7
    • 0038324480 scopus 로고    scopus 로고
    • Melioidosis
    • DOI 10.1016/S0140-6736(03)13374-0
    • White NJ. Melioidosis. Lancet. 2003;361(9370): 1715-1722. (Pubitemid 36577448)
    • (2003) Lancet , vol.361 , Issue.9370 , pp. 1715-1722
    • White, N.J.1
  • 8
    • 17444369030 scopus 로고    scopus 로고
    • Melioidosis: Epidemiology, pathophysiology, and management
    • DOI 10.1128/CMR.18.2.383-416.2005
    • Cheng AC, Currie BJ. Melioidosis: epidemiology, pathophysiology, and management. Clin Microbiol Rev. 2005;18(2):383-416. (Pubitemid 40548298)
    • (2005) Clinical Microbiology Reviews , vol.18 , Issue.2 , pp. 383-416
    • Cheng, A.C.1    Currie, B.J.2
  • 10
    • 77958046875 scopus 로고    scopus 로고
    • Incidence, risk factors and clinical epidemiology of melioidosis: A complex socioecological emerging infectious disease in the Alor Setar region of Kedah, Malaysia
    • Hassan M, et al. Incidence, risk factors and clinical epidemiology of melioidosis: a complex socioecological emerging infectious disease in the Alor Setar region of Kedah, Malaysia. BMC Infect Dis. 2010;10:302.
    • (2010) BMC Infect Dis , vol.10 , pp. 302
    • Hassan, M.1
  • 11
    • 58449125519 scopus 로고    scopus 로고
    • Human polymorphonuclear neutrophil responses to Burkholderia pseudomallei in healthy and diabetic subjects
    • Chanchamroen S, Kewcharoenwong C, Susaengrat W, Ato M, Lertmemongkolchai G. Human polymorphonuclear neutrophil responses to Burkholderia pseudomallei in healthy and diabetic subjects. Infect Immun. 2009;77(1):456-463.
    • (2009) Infect Immun , vol.77 , Issue.1 , pp. 456-463
    • Chanchamroen, S.1    Kewcharoenwong, C.2    Susaengrat, W.3    Ato, M.4    Lertmemongkolchai, G.5
  • 12
    • 75649096002 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein links oxidative stress to inflammasome activation
    • Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol. 2010;11(2):136-140.
    • (2010) Nat Immunol , vol.11 , Issue.2 , pp. 136-140
    • Zhou, R.1    Tardivel, A.2    Thorens, B.3    Choi, I.4    Tschopp, J.5
  • 13
    • 0345161549 scopus 로고    scopus 로고
    • Obligatory role of gamma interferon for host survival in a murine model of infection with Burkholderia pseudomallei
    • Santanirand P, Harley VS, Dance DA, Drasar BS, Bancroft GJ. Obligatory role of gamma interferon for host survival in a murine model of infection with Burkholderia pseudomallei. Infect Immun. 1999;67(7):3593-3600. (Pubitemid 29291534)
    • (1999) Infection and Immunity , vol.67 , Issue.7 , pp. 3593-3600
    • Santanirand, P.1    Harley, V.S.2    Dance, D.A.B.3    Drasar, B.S.4    Bancroft, G.J.5
  • 14
    • 33750467637 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase and NADPH oxidase in early control of Burkholderia pseudomallei infection in mice
    • DOI 10.1128/IAI.00966-06
    • Breitbach K, Klocke S, Tschernig T, van Rooijen N, Baumann U, Steinmetz I. Role of inducible nitric oxide synthase and NADPH oxidase in early control of Burkholderia pseudomallei infection in mice. Infect Immun. 2006;74(11):6300- 6309. (Pubitemid 44657411)
    • (2006) Infection and Immunity , vol.74 , Issue.11 , pp. 6300-6309
    • Breitbach, K.1    Klocke, S.2    Tschernig, T.3    Van Rooijen, N.4    Baumann, U.5    Steinmetz, I.6
  • 15
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity. 2000;13(5):715-725.
    • (2000) Immunity , vol.13 , Issue.5 , pp. 715-725
    • Oppmann, B.1
  • 16
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • DOI 10.1038/414813a
    • Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature. 2001;414(6865):813-820. (Pubitemid 34000785)
    • (2001) Nature , vol.414 , Issue.6865 , pp. 813-820
    • Brownlee, M.1
  • 17
    • 0036772856 scopus 로고    scopus 로고
    • IFN-gamma and pro-inflammatory cytokine production by antigen-presenting cells is dictated by intracellular thiol redox status regulated by oxygen tension
    • DOI 10.1002/1521-4141(2002010)32:10<2866::AID-IMMU2866>3.0.CO;2-V
    • Murata Y, Ohteki T, Koyasu S, Hamuro J. IFN-gamma and pro-inflammatory cytokine production by antigen-presenting cells is dictated by intracellular thiol redox status regulated by oxygen tension. Eur J Immunol. 2002;32(10):2866-2873. (Pubitemid 35238179)
    • (2002) European Journal of Immunology , vol.32 , Issue.10 , pp. 2866-2873
    • Murata, Y.1    Ohteki, T.2    Koyasu, S.3    Hamuro, J.4
  • 18
    • 77951888771 scopus 로고    scopus 로고
    • Glutathione-redox balance regulates c-rel-driven IL-12 production in macrophages: Possible implications in antituberculosis immunotherapy
    • Alam K, Ghousunnissa S, Nair S, Valluri VL, Mukhopadhyay S. Glutathione-redox balance regulates c-rel-driven IL-12 production in macrophages: possible implications in antituberculosis immunotherapy. J Immunol. 2010;184(6):2918-2929.
    • (2010) J Immunol , vol.184 , Issue.6 , pp. 2918-2929
    • Alam, K.1    Ghousunnissa, S.2    Nair, S.3    Valluri, V.L.4    Mukhopadhyay, S.5
  • 19
    • 79951508487 scopus 로고    scopus 로고
    • Impact of streptozotocin-induced diabetes on functional responses of dendritic cells and macrophages towards Burkholderia pseudomallei
    • Williams NL, Morris JL, Rush C, Govan BL, Ketheesan N. Impact of streptozotocin-induced diabetes on functional responses of dendritic cells and macrophages towards Burkholderia pseudomallei. FEMS Immunol Med Microbiol. 2011;61(2):218-227.
    • (2011) FEMS Immunol Med Microbiol , vol.61 , Issue.2 , pp. 218-227
    • Williams, N.L.1    Morris, J.L.2    Rush, C.3    Govan, B.L.4    Ketheesan, N.5
  • 20
    • 81155150056 scopus 로고    scopus 로고
    • Altered macrophage function is associated with severe Burkholderia pseudomallei infection in a murine model of type 2 diabetes
    • Hodgson KA, Morris JL, Feterl ML, Govan BL, Ketheesan N. Altered macrophage function is associated with severe Burkholderia pseudomallei infection in a murine model of type 2 diabetes. Microbes Infect. 2011;13(14-15):1177-1184.
    • (2011) Microbes Infect , vol.13 , Issue.14-15 , pp. 1177-1184
    • Hodgson, K.A.1    Morris, J.L.2    Feterl, M.L.3    Govan, B.L.4    Ketheesan, N.5
  • 21
    • 0021219926 scopus 로고
    • The effects of buthionine sulphoximine (BSO) on glutathione depletion and xenobiotic biotransformation
    • DOI 10.1016/0006-2952(84)90598-7
    • Drew R, Miners JO. The effects of buthionine sulphoximine (BSO) on glutathione depletion and xenobiotic biotransformation. Biochem Pharmacol. 1984;33(19):2989-2994. (Pubitemid 14044593)
    • (1984) Biochemical Pharmacology , vol.33 , Issue.19 , pp. 2989-2994
    • Drew, R.1    Miners, J.O.2
  • 22
    • 0037090226 scopus 로고    scopus 로고
    • Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense
    • DOI 10.1086/340042
    • Villa P, Saccani A, Sica A, Ghezzi P. Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense. J Infect Dis. 2002;185(8):1115-1120. (Pubitemid 34297769)
    • (2002) Journal of Infectious Diseases , vol.185 , Issue.8 , pp. 1115-1120
    • Villa, P.1    Saccani, A.2    Sica, A.3    Ghezzi, P.4
  • 23
    • 0032708938 scopus 로고    scopus 로고
    • Elevated plasma concentrations of interferon (IFN)-gamma and the IFN-gamma-inducing cytokines interleukin (IL)-18, IL-12, and IL-15 in severe melioidosis
    • Lauw FN, et al. Elevated plasma concentrations of interferon (IFN)-gamma and the IFN-gamma-inducing cytokines interleukin (IL)-18, IL-12, and IL-15 in severe melioidosis. J Infect Dis. 1999;180(6):1878-1885.
    • (1999) J Infect Dis , vol.180 , Issue.6 , pp. 1878-1885
    • Lauw, F.N.1
  • 24
    • 0036150976 scopus 로고    scopus 로고
    • Model of differential susceptibility to mucosal Burkholderia pseudomallei infection
    • DOI 10.1128/IAI.70.2.504-511.2002
    • Liu B, Koo GC, Yap EH, Chua KL, Gan YH. Model of differential susceptibility to mucosal Burkholderia pseudomallei infection. Infect Immun. 2002;70(2):504-511. (Pubitemid 34083807)
    • (2002) Infection and Immunity , vol.70 , Issue.2 , pp. 504-511
    • Liu, B.1    Koo, G.C.2    Yap, E.H.3    Chua, K.L.4    Gan, Y.-H.5
  • 25
    • 79953764920 scopus 로고    scopus 로고
    • Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis
    • Koh GCKW, et al. Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis. Clin Infect Dis. 2011;52(6):717-725.
    • (2011) Clin Infect Dis , vol.52 , Issue.6 , pp. 717-725
    • Koh, G.1
  • 31
    • 0035985352 scopus 로고    scopus 로고
    • Thiol antioxidants inhibit the formation of the interleukin-12 heterodimer: A novel mechanism for the inhibition of IL-12 production
    • Mazzeo D, et al. Thiol antioxidants inhibit the formation of the interleukin-12 heterodimer: a novel mechanism for the inhibition of IL-12 production. Cytokine. 2002;17(6):285-293.
    • (2002) Cytokine , vol.17 , Issue.6 , pp. 285-293
    • Mazzeo, D.1
  • 32
    • 33646152522 scopus 로고    scopus 로고
    • Human host genetic factors in mycobacterial and Salmonella infection: Lessons from single gene disorders in IL-12/IL-23-dependent signaling that affect innate and adaptive immunity
    • van de Vosse E, Ottenhoff THM. Human host genetic factors in mycobacterial and Salmonella infection: lessons from single gene disorders in IL-12/IL-23-dependent signaling that affect innate and adaptive immunity. Microbes Infect. 2006;8(4):1167-1173.
    • (2006) Microbes Infect , vol.8 , Issue.4 , pp. 1167-1173
    • Van De Vosse, E.1    Ottenhoff, T.H.M.2
  • 33
    • 33745214259 scopus 로고    scopus 로고
    • Interleukin 15-dependent crosstalk between conventional and plasmacytoid dendritic cells is essential for CpG-induced immune activation
    • DOI 10.1038/ni1348, PII N1348
    • Kuwajima S, Sato T, Ishida K, Tada H, Tezuka H, Ohteki T. Interleukin 15-dependent crosstalk between conventional and plasmacytoid dendritic cells is essential for CpG-induced immune activation. Nat Immunol. 2006;7(7):740-746. (Pubitemid 43905873)
    • (2006) Nature Immunology , vol.7 , Issue.7 , pp. 740-746
    • Kuwajima, S.1    Sato, T.2    Ishida, K.3    Tada, H.4    Tezuka, H.5    Ohteki, T.6
  • 34
    • 50849133574 scopus 로고    scopus 로고
    • Signalling, inflammation and arthritis: Crossed signals: The role of interleukin-15 and -18 in autoimmunity
    • Carroll HP, Paunovic V, Gadina M. Signalling, inflammation and arthritis: Crossed signals: the role of interleukin-15 and -18 in autoimmunity. Rheumatology. 2008;47(9):1269-1277.
    • (2008) Rheumatology , vol.47 , Issue.9 , pp. 1269-1277
    • Carroll, H.P.1    Paunovic, V.2    Gadina, M.3
  • 36
    • 0035863737 scopus 로고    scopus 로고
    • + T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens
    • Lertmemongkolchai G, Cai G, Hunter CA, Bancroft GJ. Bystander activation of CD8+ T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens. J Immunol. 2001;166(2):1097-1105. (Pubitemid 32060268)
    • (2001) Journal of Immunology , vol.166 , Issue.2 , pp. 1097-1105
    • Lertmemongkolchai, G.1    Cai, G.2    Hunter, C.A.3    Bancroft, G.J.4
  • 37
    • 65549149098 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of human memory T cell responses to Burkholderia pseudomallei
    • Tippayawat P, et al. Phenotypic and functional characterization of human memory T cell responses to Burkholderia pseudomallei. PLoS Negl Trop Dis. 2009;3(4):e407.
    • (2009) PLoS Negl Trop Dis , vol.3 , Issue.4
    • Tippayawat, P.1
  • 38
    • 33745808029 scopus 로고    scopus 로고
    • A three-cell model for activation of naïve T helper cells
    • DOI 10.1111/j.1365-3083.2006.01782.x
    • Corthay A. A three-cell model for activation of naïve T helper cells. Scand J Immunol. 2006;64(2):93-96. (Pubitemid 44034312)
    • (2006) Scandinavian Journal of Immunology , vol.64 , Issue.2 , pp. 93-96
    • Corthay, A.1
  • 39
    • 62249096975 scopus 로고    scopus 로고
    • Glutathione dysregulation and the etiology and progression of human diseases
    • Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL. Glutathione dysregulation and the etiology and progression of human diseases. Biol Chem. 2009;390(3):191-214.
    • (2009) Biol Chem , vol.390 , Issue.3 , pp. 191-214
    • Ballatori, N.1    Krance, S.M.2    Notenboom, S.3    Shi, S.4    Tieu, K.5    Hammond, C.L.6
  • 40
    • 0031005935 scopus 로고    scopus 로고
    • Erythrocyte thiol status regulates band 3 phosphotyrosine level via oxidation/reduction of band 3-associated phosphotyrosine phosphatase
    • DOI 10.1016/S0014-5793(97)00263-9, PII S0014579397002639
    • Zipser Y, Piade A, Kosower NS. Erythrocyte thiol status regulates band 3 phosphotyrosine level via oxidation/reduction of band 3-associated phosphotyrosine phosphatase. FEBS Lett. 1997;406(1-2):126-130. (Pubitemid 27156973)
    • (1997) FEBS Letters , vol.406 , Issue.1-2 , pp. 126-130
    • Zipser, Y.1    Piade, A.2    Kosower, N.S.3
  • 41
    • 11244277091 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases and the immune response
    • DOI 10.1038/nri1530
    • Mustelin T, Vang T, Bottini N. Protein tyrosine phosphatases and the immune response. Nat Rev Immunol. 2005;5(1):43-57. (Pubitemid 40070330)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.1 , pp. 43-57
    • Mustelin, T.1    Vang, T.2    Bottini, N.3
  • 42
    • 0029991451 scopus 로고    scopus 로고
    • + lymphocytes from HIV-infected patients display impaired CD45-associated tyrosine phosphatase activity which is enhanced by anti-oxidants
    • Cayota A, Vuillier F, Gonzalez G, Dighiero G. CD4+ lymphocytes from HIV-infected patients display impaired CD45-associated tyrosine phosphatase activity which is enhanced by anti-oxidants. Clin Exp Immunol. 1996;104(1):11-17. (Pubitemid 26106038)
    • (1996) Clinical and Experimental Immunology , vol.104 , Issue.1 , pp. 11-17
    • Cayota, A.1    Vuillier, F.2    Gonzalez, G.3    Dighiero, G.4
  • 43
    • 15844413589 scopus 로고    scopus 로고
    • Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-1beta and tumor necrosis factor-alpha in mouse endothelial cells
    • DOI 10.1074/jbc.271.25.15146
    • Urata Y, et al. Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-1beta and tumor necrosis factor-alpha in mouse endothelial cells. J Biol Chem. 1996;271(25):15146-15152. (Pubitemid 26194994)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.25 , pp. 15146-15152
    • Urata, Y.1    Yamamoto, H.2    Goto, S.3    Tsushima, H.4    Akazawa, S.5    Yamashita, S.6    Nagataki, S.7    Kondo, T.8
  • 45
    • 0035851024 scopus 로고    scopus 로고
    • Advanced glycation endproducts change glutathione redox status in SH-SY5Y human neuroblastoma cells by a hydrogen peroxide dependent mechanism
    • DOI 10.1016/S0304-3940(01)02174-7, PII S0304394001021747
    • Deuther-Conrad W, Loske C, Schinzel R, Dringen R, Riederer P, Münch G. Advanced glycation endproducts change glutathione redox status in SH-SY5Y human neuroblastoma cells by a hydrogen peroxide dependent mechanism. Neurosci Lett. 2001;312(1):29-32. (Pubitemid 32907545)
    • (2001) Neuroscience Letters , vol.312 , Issue.1 , pp. 29-32
    • Deuther-Conrad, W.1    Loske, C.2    Schinzel, R.3    Dringen, R.4    Riederer, P.5    Munch, G.6
  • 46
    • 0037390720 scopus 로고    scopus 로고
    • Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2
    • Nencioni L, et al. Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2. FASEB J. 2003;17(6):758-760.
    • (2003) FASEB J , vol.17 , Issue.6 , pp. 758-760
    • Nencioni, L.1
  • 47
    • 78349309039 scopus 로고    scopus 로고
    • Melioidosis: Advances in diagnosis and treatment
    • Cheng AC. Melioidosis: advances in diagnosis and treatment. Curr Opin Infect Dis. 2010;23(6):554-559.
    • (2010) Curr Opin Infect Dis , vol.23 , Issue.6 , pp. 554-559
    • Cheng, A.C.1
  • 49
    • 0345791422 scopus 로고    scopus 로고
    • Adjunctive Granulocyte Colony-Stimulating Factor for Treatment of Septic Shock Due to Melioidosis
    • DOI 10.1086/380456
    • Cheng AC, Stephens DP, Anstey NM, Currie BJ. Adjunctive granulocyte colony-stimulating factor for treatment of septic shock due to melioidosis. Clin Infect Dis. 2004;38(1):32-37. (Pubitemid 38045870)
    • (2004) Clinical Infectious Diseases , vol.38 , Issue.1 , pp. 32-37
    • Cheng, A.C.1    Stephens, D.P.2    Anstey, N.M.3    Currie, B.J.4
  • 51
    • 43949122537 scopus 로고    scopus 로고
    • Interleukin-8 induction by Burkholderia pseudomallei can occur without Toll-like receptor signaling but requires a functional type III secretion system
    • DOI 10.1086/587905
    • Hii CS, Sun GW, Goh JWK, Lu J, Stevens MP, Gan YH. Interleukin-8 induction by Burkholderia pseudomallei can occur without Toll-like receptor signaling but requires a functional type III secretion system. J Infect Dis. 2008;197(11):1537-1547. (Pubitemid 351706484)
    • (2008) Journal of Infectious Diseases , vol.197 , Issue.11 , pp. 1537-1547
    • Hii, C.-S.1    Guang, W.S.2    Goh, J.W.K.3    Lu, J.4    Stevens, M.P.5    Gan, Y.-H.6
  • 52
    • 0035710746 scopus 로고    scopus 로고
    • -DeltaDeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25(4):402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.