Nomilin inhibits metastasis via induction of apoptosis and regulates the activation of transcription factors and the cytokine profile in B16F-10 cells

Integrative Cancer Therapies

Volumn 11, Issue 1, 2012, Pages 48-60

  Pratheeshkumar, Poyil ^a   Raphael, Tharakan J ^a   Kuttan, Girija ^a  

^a AMALA CANCER RESEARCH CENTRE   (India)

Author keywords

apoptosis; B16F 10; caspases; matrix metalloproteinases; metastasis; NF B; nomilin; proinflammatory cytokines

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; ACTIVATING TRANSCRIPTION FACTOR 4; CASPASE 3; CASPASE 9; CYCLIN D1; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIQUID PARAFFIN; MATRIX METALLOPROTEINASE; NOMILIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P27; PROTEIN P53; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; C57BL 6 MOUSE; CANCER INVASION; CANCER SURVIVAL; CELL ASSAY; CELL CYCLE PROGRESSION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; GENE EXPRESSION; GENE SEQUENCE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG METASTASIS; MALE; MELANOMA CELL; METASTASIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL RATE; TREATMENT RESPONSE;

ACTIVATING TRANSCRIPTION FACTOR 2; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZOXEPINS; CASPASE 3; CASPASE 9; CELL CYCLE; CELL LINE, TUMOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DNA FRAGMENTATION; DOWN-REGULATION; LIMONINS; LUNG NEOPLASMS; MALE; MATRIX METALLOPROTEINASES; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NF-KAPPA B; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-BCL-2; SURVIVAL RATE; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84861831365     PISSN: 15347354     EISSN: 1552695X     Source Type: Journal    
DOI: 10.1177/1534735411403307     Document Type: Article

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