Modeling longitudinal daily seizure frequency data from pregabalin add-on treatment

Journal of Clinical Pharmacology

Volumn 52, Issue 6, 2012, Pages 880-892

  Ahn, Jae Eun ^a   Plan, Elodie L ^b   Karlsson, Mats O ^b   Miller, Raymond ^a,c  

^a PFIZER INC   (United States)

^b UPPSALA UNIVERSITY   (Sweden)

^c DAIICHI SANKYO INC   (United States)

Author keywords

count data; epilepsy; negative binomial distribution; NONMEM 7; pregabalin

Indexed keywords

CARBAMAZEPINE; LAMOTRIGINE; PHENYTOIN; PLACEBO; PREGABALIN; TOPIRAMATE; VALPROIC ACID;

ADD ON THERAPY; ADOLESCENT; ADULT; AGED; ARTICLE; BINOMIAL DISTRIBUTION; CHILD; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; FEMALE; FOCAL EPILEPSY; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; SCHOOL CHILD; SIMULATION; TIME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTICONVULSANTS; CHILD; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG RESISTANCE; DRUG THERAPY, COMBINATION; EPILEPSY; FEMALE; GAMMA-AMINOBUTYRIC ACID; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; PROGNOSIS; SEVERITY OF ILLNESS INDEX; TIME FACTORS; YOUNG ADULT;

EID: 84861819357     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270011407193     Document Type: Article

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