In vivo controlled release and prolonged antitumor effects of 2-methoxyestradiol solid lipid nanoparticles incorporated into a thermosensitive hydrogel

Drug Delivery

Volumn 19, Issue 4, 2012, Pages 188-193

  Guo, Xinhong ^a,b   Xing, Yabing ^a   Zhang, Xinxin ^a   Li, Junmei ^a   Mei, Qian ^a   Zhang, Hongling ^a   Chen, Chengqun ^a   Zhang, Zhenzhong ^a   Cui, Fude ^a,b  

^a ZHENGZHOU UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

2 methoxyestradiol; Prolonged antitumor effect; Solid lipid nanoparticles; Thermosensitive hydrogel; Two phase delivery system

Indexed keywords

2 METHOXYESTRADIOL; COUMARIN; SOLID LIPID NANOPARTICLE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BAGG ALBINO MOUSE; BREAST CANCER; CANCER CELL; CANCER CHEMOTHERAPY; CANCER INHIBITION; CLINICAL EFFECTIVENESS; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; DRUG SAFETY; FEMALE; FLUORESCENCE; HEAT SENSITIVITY; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; INOCULATION; LEUKOCYTE; LOCAL THERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN TUMOR; SUBCUTANEOUS TISSUE TUMOR; WEIGHT REDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; BODY TEMPERATURE REGULATION; CELL LINE, TUMOR; CELL SURVIVAL; DELAYED-ACTION PREPARATIONS; ESTRADIOL; FEMALE; HYDROGELS; MICE; MICE, INBRED BALB C; NANOPARTICLES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84861814392     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2012.690002     Document Type: Article

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