A mesofluidics-based test platform for systematic development of scaffolds for in situ cardiovascular tissue engineering

Tissue Engineering - Part C: Methods

Volumn 18, Issue 6, 2012, Pages 475-485

  Smits, Anthal I P M ^a   Driessen Mol, Anita ^a   Bouten, Carlijn V C ^a   Baaijens, Frank P T ^a  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD VESSELS; CELL ADHESION; CELL CULTURE; CELLS; COMPUTATIONAL FLUID DYNAMICS; CONFOCAL MICROSCOPY; FLUIDICS; HEMODYNAMICS; THREE DIMENSIONAL; TISSUE;

3D SCAFFOLDS; BIODEGRADABLE SCAFFOLD; CAPROLACTONE; CARDIOVASCULAR TISSUE ENGINEERING; CELL SUSPENSION; COMPUTATIONAL FLUID DYNAMICS MODELS; CONFOCAL LASER SCANNING MICROSCOPY; CROSS FLOWS; ELECTROSPUNS; FIBER DIAMETERS; FLOW PROFILE; HIGH DEMAND; HOST CELLS; HUMAN PERIPHERAL BLOOD; IN-SITU; IN-VITRO; IN-VITRO TESTS; IN-VIVO; MICROBEADS; PHYSIOLOGICAL RANGE; REPOPULATION; SCAFFOLD PROPERTIES; SYNTHETIC SCAFFOLDS; TEST PLATFORMS; TISSUE FORMATION; WALL SHEAR STRESS;

SCAFFOLDS (BIOLOGY);

MICROSPHERE; POLYCAPROLACTONE; POLYESTER; TISSUE SCAFFOLD;

ARTICLE; CARDIOVASCULAR SYSTEM; CHEMISTRY; CYTOLOGY; FLOW KINETICS; FLUORESCENCE; HUMAN; INSTRUMENTATION; MECHANICAL STRESS; METABOLISM; METHODOLOGY; MONONUCLEAR CELL; POROSITY; PRESSURE; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING;

CARDIOVASCULAR SYSTEM; FLUORESCENCE; HUMANS; LEUKOCYTES, MONONUCLEAR; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; POLYESTERS; POROSITY; PRESSURE; RHEOLOGY; STRESS, MECHANICAL; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84861807501     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2011.0458     Document Type: Article

References (56)

1. Rosamond, W., Flegal, K., Furie, K., Go, A., Greenlund, K., Haase, N., Hailpern, S.M., Ho, M., Howard, V., Kissela, B., Kittner, S., Lloyd-Jones, D., McDermott, M., Meigs, J., Moy, C., Nichol, G., O'Donnell, C., Roger, V., Sorlie, P., Steinberger, J., Thom, T., Wilson, M., and Hong, Y. Heart disease and stroke statistics-2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 117, e25, 2008.
2. El-Hamamsy, I., Eryigit, Z., Stevens, L.M., Sarang, Z., George, R., Clark, L., Melina, G., Takkenberg, J.J., and Yacoub, M.H. Long-term outcomes after autograft versus homograft aortic root replacement in adults with aortic valve disease: a randomised controlled trial. Lancet 376, 524, 2010.
3. Puvimanasinghe, J.P., Takkenberg, J.J., Edwards, M.B., Eijkemans, M.J., Steyerberg, E.W., Van Herwerden, L.A., Taylor, K.M., Grunkemeier, G.L., Habbema, J.D., and Bogers, A.J. Comparison of outcomes after aortic valve replacement with a mechanical valve or a bioprosthesis using microsimulation. Heart (British Cardiac Society) 90, 1172, 2004.
4. Chlupac, J., Filova, E., and Bacakova, L. Blood vessel replacement: 50 years of development and tissue engineering paradigms in vascular surgery. Physiol Res 58 (Suppl 2), S119, 2009.
5. Mol, A., Smits, A.I., Bouten, C.V., and Baaijens, F.P. Tissue engineering of heart valves: advances and current challenges. Expert Rev Med Devices 6, 259, 2009.
6. Mendelson, K., and Schoen, F.J. Heart valve tissue engineering: concepts, approaches, progress, and challenges. Ann Biomed Eng 34, 1799, 2006.
7. Schoen, F.J. Heart valve tissue engineering: quo vadis? Curr Opin Biotechnol 22, 1, 2011.
8. Avci-Adali, M., Paul, A., Ziemer, G., and Wendel, H.P. New strategies for in vivo tissue engineering by mimicry of homing factors for self-endothelialisation of blood contacting materials. Biomaterials 29, 3936, 2008.
9. de Mel, A., Jell, G., Stevens, M.M., and Seifalian, A.M. Biofunctionalization of biomaterials for accelerated in situ endothelialization: a review. Biomacromolecules 9, 2969, 2008.
10. Avci-Adali, M., Ziemer, G., and Wendel, H.P. Induction of EPC homing on biofunctionalized vascular grafts for rapid in vivo self-endothelialization-a review of current strategies. Biotechnol Adv 28, 119, 2010.
11. Aoki, J., Serruys, P.W., van Beusekom, H., Ong, A.T., McFadden, E.P., Sianos, G., van der Giessen, W.J., Regar, E., de Feyter, P.J., Davis, H.R., Rowland, S., and Kutryk, M.J. Endothelial progenitor cell capture by stents coated with antibody against CD34: the HEALING-FIM (Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth-First In Man) Registry. J Am Coll Cardiol 45, 1574, 2005.
12. Klomp, M., Beijk, M.A., and de Winter, R.J. Genous endothelial progenitor cell-capturing stent system: a novel stent technology. Expert Rev Med Devices 6, 365, 2009.
13. Miglionico, M., Patti, G., D'Ambrosio, A., and Di Sciascio, G. Percutaneous coronary intervention utilizing a new endothelial progenitor cells antibody-coated stent: a prospective single-center registry in high-risk patients. Catheter Cardiovasc Interv 71, 600, 2008.
14. Markway, B.D., McCarty, O.J., Marzec, U.M., Courtman, D.W., Hanson, S.R., and Hinds, M.T. Capture of flowing endothelial cells using surface-immobilized anti-kinase insert domain receptor antibody. Tissue Eng Part C Methods 14, 97, 2008.
15. Rotmans, J.I., Heyligers, J.M., Verhagen, H.J., Velema, E., Nagtegaal, M.M., de Kleijn, D.P., de Groot, F.G., Stroes, E.S., and Pasterkamp, G. In vivo cell seeding with anti-CD34 antibodies successfully accelerates endothelialization but stimulates intimal hyperplasia in porcine arteriovenous expanded polytetrafluoroethylene grafts. Circulation 112, 12, 2005.
16. Rossi, M.L., Zavalloni, D., Gasparini, G.L., Mango, R., Belli, G., and Presbitero, P. The first report of late stent thrombosis leading to acute myocardial infarction in patient receiving the new endothelial progenitor cell capture stent. Int J Cardiol 141, e20, 2010.
17. Sales, V.L., Engelmayr, G.C., Jr., Mettler, B.A., Johnson, J.A., Jr., Sacks, M.S., and Mayer, J.E., Jr. Transforming growth factor-beta1 modulates extracellular matrix production, proliferation, and apoptosis of endothelial progenitor cells in tissue-engineering scaffolds. Circulation 114, I193, 2006.
18. Sales, V.L., Mettler, B.A., Engelmayr, G.C., Jr., Aikawa, E., Bischoff, J., Martin, D.P., Exarhopoulos, A., Moses, M.A., Schoen, F.J., Sacks, M.S., and Mayer, J.E., Jr. Endothelial progenitor cells as a sole source for ex vivo seeding of tissueengineered heart valves. Tissue Eng Part A 16, 257, 2010.
19. Simper, D., Stalboerger, P.G., Panetta, C.J., Wang, S., and Caplice, N.M. Smooth muscle progenitor cells in human blood. Circulation 106, 1199, 2002.
20. Langer, H.F., von der Ruhr, J.W., Daub, K., Schoenberger, T., Stellos, K., May, A.E., Schnell, H., Gauss, A., Hafner, R., Lang, P., Schumm, M., Buhring, H.J., Klingel, K., Conrad, S., Schaller, M., van Zandvoort, M., Jung, G., Dimmeler, S., Skutella, T., and Gawaz, M. Capture of endothelial progenitor cells by a bispecific protein/monoclonal antibody molecule induces reendothelialization of vascular lesions. J Mol Med 88, 687, 2010.
21. van Oostrom, O., Fledderus, J.O., de Kleijn, D., Pasterkamp, G., and Verhaar, M.C. Smooth muscle progenitor cells: friend or foe in vascular disease? Curr Stem Cell Res Ther 4, 131, 2009.
22. Vincentelli, A., Wautot, F., Juthier, F., Fouquet, O., Corseaux, D., Marechaux, S., Le Tourneau, T., Fabre, O., Susen, S., Van Belle, E., Mouquet, F., Decoene, C., Prat, A., and Jude, B. In vivo autologous recellularization of a tissue-engineered heart valve: are bone marrow mesenchymal stem cells the best candidates? J Thorac Cardiovasc Surg 134, 424, 2007.
23. Timmermans, F., Plum, J., Yoder, M.C., Ingram, D.A., Vandekerckhove, B., and Case, J. Endothelial progenitor cells: identity defined? J Cell Mol Med 1, 87, 2008.
24. Weston, M.W., LaBorde, D.V., and Yoganathan, A.P. Estimation of the shear stress on the surface of an aortic valve leaflet. Ann Biomed Eng 27, 572, 1999.
25. Sacks, M.S., and Yoganathan, A.P. Heart valve function: a biomechanical perspective. Philos Trans R Soc Lond 362, 1369, 2007.
26. Sato, M., and Ohashi, T. Biorheological views of endothelial cell responses to mechanical stimuli. Biorheology 42, 421, 2005.
27. Anderson, E.J., Falls, T.D., Sorkin, A.M., and Knothe Tate, M.L. The imperative for controlled mechanical stresses in unraveling cellular mechanisms of mechanotransduction. Biomed Eng Online 5, 27, 2006.
28. Angelos, M.G., Brown, M.A., Satterwhite, L.L., Levering, V.W., Shaked, N.T., and Truskey, G.A. Dynamic adhesion of umbilical cord blood endothelial progenitor cells under laminar shear stress. Biophys J 99, 3545, 2010.
29. Plouffe, B.D., Kniazeva, T., Mayer, J.E., Jr., Murthy, S.K., and Sales, V.L. Development of microfluidics as endothelial progenitor cell capture technology for cardiovascular tissue engineering and diagnostic medicine. FASEB J 23, 3309, 2009.
30. Plouffe, B.D., Njoka, D.N., Harris, J., Liao, J., Horick, N.K., Radisic, M., and Murthy, S.K. Peptide-mediated selective adhesion of smooth muscle and endothelial cells in microfluidic shear flow. Langmuir 23, 5050, 2007.
31. Plouffe, B.D., Radisic, M., and Murthy, S.K. Microfluidic depletion of endothelial cells, smooth muscle cells, and fibroblasts from heterogeneous suspensions. Lab Chip 8, 462, 2008.
32. Ueda, A., Koga, M., Ikeda, M., Kudo, S., and Tanishita, K. Effect of shear stress on microvessel network formation of endothelial cells with in vitro three-dimensional model. Am J Physiol 287, H994, 2004.
33. Kang, H., Bayless, K.J., and Kaunas, R. Fluid shear stress modulates endothelial cell invasion into three-dimensional collagen matrices. Am J Physiol 295, H2087, 2008.
34. de Mel, A., Punshon, G., Ramesh, B., Sarkar, S., Darbyshire, A., Hamilton, G., and Seifalian, A.M. In situ endothelialization potential of a biofunctionalised nanocomposite biomaterial-based small diameter bypass graft. Biomed Mater Eng 19, 317, 2009.
35. Chen, M., Michaud, H., and Bhowmick, S. Controlled vacuum seeding as a means of generating uniform cellular distribution in electrospun polycaprolactone (PCL) scaffolds. J Biomech Eng 131, 074521, 2009.
36. Pham, Q.P., Sharma, U., and Mikos, A.G. Electrospun poly(epsilon- caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration. Biomacromolecules 7, 2796, 2006.
37. Lowery, J.L., Datta, N., and Rutledge, G.C. Effect of fiber diameter, pore size and seeding method on growth of human dermal fibroblasts in electrospun poly(epsiloncaprolactone) fibrous mats. Biomaterials 31, 491, 2010.
38. Santoro, R., Olivares, A.L., Brans, G., Wirz, D., Longinotti, C., Lacroix, D., Martin, I., and Wendt, D. Bioreactor based engineering of large-scale human cartilage grafts for joint resurfacing. Biomaterials 31, 8946, 2010.
39. Young, E.W., and Simmons, C.A. Macro-and microscale fluid flow systems for endothelial cell biology. Lab Chip 10, 143, 2010.
40. Bacabac, R.G., Smit, T.H., Cowin, S.C., Van Loon, J.J., Nieuwstadt, F.T., Heethaar, R., and Klein-Nulend, J. Dynamic shear stress in parallel-plate flow chambers. J Biomech 38, 159, 2005.
41. Nauman, E.A., Risic, K.J., Keaveny, T.M., and Satcher, R.L. Quantitative assessment of steady and pulsatile flow fields in a parallel plate flow chamber. Ann Biomed Eng 27, 194, 1999.
42. Walburn, F.J., and Schneck, D.J. A constitutive equation for whole human blood. Biorheology 13, 201, 1976.
43. Lee, J.H., Wang, H., Kaplan, J.B., and Lee, W.Y. Microfluidic approach to create three-dimensional tissue models for biofilm-related infection of orthopaedic implants. Tissue Eng Part C Methods 17, 39, 2011.
44. Chung, S., Sudo, R., Mack, P.J., Wan, C.R., Vickerman, V., and Kamm, R.D. Cell migration into scaffolds under coculture conditions in a microfluidic platform. Lab Chip 9, 269, 2009.
45. Vickerman, V., Blundo, J., Chung, S., and Kamm, R. Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging. Lab Chip 8, 1468, 2008.
46. Rambani, K., Vukasinovic, J., Glezer, A., and Potter, S.M. Culturing thick brain slices: an interstitial 3D microperfusion system for enhanced viability. J Neurosci Methods 180, 243, 2009.
47. Chouinard, J.A., Gagnon, S., Couture, M.G., Levesque, A., and Vermette, P. Design and validation of a pulsatile perfusion bioreactor for 3D high cell density cultures. Biotechnol Bioeng 104, 1215, 2009.
48. Anderson, E.J., and Knothe Tate, M.L. Open access to novel dual flow chamber technology for in vitro cell mechanotransduction, toxicity and pharamacokinetic studies. Biomed Eng Online 6, 46, 2007.
49. Melchels, F.P., Tonnarelli, B., Olivares, A.L., Martin, I., Lacroix, D., Feijen, J., Wendt, D.J., and Grijpma, D.W. The influence of the scaffold design on the distribution of adhering cells after perfusion cell seeding. Biomaterials 32, 2878, 2011.
50. Balguid, A., Mol, A., van Marion, M.H., Bank, R.A., Bouten, C.V., and Baaijens, F.P. Tailoring fiber diameter in electrospun poly(epsilon- caprolactone) scaffolds for optimal cellular infiltration in cardiovascular tissue engineering. Tissue Eng Part A 15, 437, 2009.
51. Tang, Y., Wong, C., Wang, H., Sutti, A., Kirkland, M., Wang, X., and Lin, T. Three-dimensional tissue scaffolds from interbonded poly(epsilon- caprolactone) fibrous matrices with controlled porosity. Tissue Eng Part C Methods 17, 209, 2011.
52. Hibino, N., Yi, T., Duncan, D.R., Rathore, A., Dean, E., Naito, Y., Dardik, A., Kyriakides, T., Madri, J., Pober, J.S., Shinoka, T., and Breuer, C.K. A critical role for macrophages in neovessel formation and the development of stenosis in tissue-engineered vascular grafts. FASEB J 25, 4253, 2011.
53. Roh, J.D., Sawh-Martinez, R., Brennan, M.P., Jay, S.M., Devine, L., Rao, D.A., Yi, T., Mirensky, T.L., Nalbandian, A., Udelsman, B., Hibino, N., Shinoka, T., Saltzman, W.M., Snyder, E., Kyriakides, T.R., Pober, J.S., and Breuer, C.K. Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling. Proc Natl Acad Sci USA 107, 4669, 2010.
54. Anderson, J.M., Rodriguez, A., and Chang, D.T. Foreign body reaction to biomaterials. Semin Immunol 20, 86, 2008.
55. Stellos, K., Gnerlich, S., Kraemer, B., Lindemann, S., and Gawaz, M. Platelet interaction with progenitor cells: vascular regeneration or inquiry? Pharmacol Rep 60, 101, 2008.
56. van den Broek, C.N., Pullens, R.A., Frobert, O., Rutten, M.C., den Hartog, W.F., and van de Vosse, F.N. Medium with blood-analog mechanical properties for cardiovascular tissue culturing. Biorheology 45, 651, 2008.