Does pupil constriction under blue and green monochromatic light exposure change with age?

Journal of Biological Rhythms

Volumn 27, Issue 3, 2012, Pages 257-264

  Daneault, Véronique ^a,b,c   Vandewalle, Gilles ^a,b,c   Hébert, Marc ^d   Teikari, Petteri ^e,f   Mure, Ludovic S ^e,f   Doyon, Julien ^a,c   Gronfier, Claude ^e,f   Cooper, Howard M ^e,f   Dumont, Marie ^b   Carrier, Julie ^a,b,c  

^a CENTRE DE RECHERCHE   (Canada)

^b HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d CENTRE DE RECHERCHE DE L INSTITUT UNIVERSITAIRE EN SANTÉ MENTALE DE QUÉBEC   (Canada)

^e STEM CELL AND BRAIN RESEARCH INSTITUTE   (France)

^f UNIVERSITÉ LYON 1   (France)

Author keywords

aging; circadian; melanopsin; monochromatic light; nonvisual responses to light; pupil constriction; pupil light reflex (PLR)

Indexed keywords

MELANOPSIN; MELATONIN; SCOTOPSIN;

ADULT; AGE; AGED; AGING; ARTICLE; CIRCADIAN RHYTHM; FEMALE; HUMAN; LIGHT; MALE; METABOLISM; MIDDLE AGED; PHOTOSTIMULATION; PHYSIOLOGY; PUPIL; SECRETION (PROCESS); VISION;

ADULT; AGE FACTORS; AGED; AGING; CIRCADIAN RHYTHM; FEMALE; HUMANS; LIGHT; MALE; MELATONIN; MIDDLE AGED; PHOTIC STIMULATION; PUPIL; ROD OPSINS; VISION, OCULAR;

EID: 84861805672     PISSN: 07487304     EISSN: 15524531     Source Type: Journal    
DOI: 10.1177/0748730412441172     Document Type: Article

References (55)

1. Beck AT, Epstein N, Brown G, Steer RA. An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol. 1988 ; 56: 893-897 (Pubitemid 19008360)
2. Berson DM. Strange vision: ganglion cells as circadian photoreceptors. Trends Neurosci. 2003 ; 26: 314-320 (Pubitemid 36694319)
3. Berson DM, Castrucci AM, Provencio I. Morphology and mosaics of melanopsin-expressing retinal ganglion cell types in mice. J Comp Neurol. 2010 ; 518: 2405-2422
4. Bitsios P, Prettyman R, Szabadi E. Changes in autonomic function with age: a study of pupillary kinetics in healthy young and old people. Age Ageing. 1996 ; 25: 432-438 (Pubitemid 26418171)
5. Brainard GC, Hanifin JP. Photons, clocks, and consciousness. J Biol Rhythms. 2005 ; 20: 314-325 (Pubitemid 41022976)
6. Brown TM, Gias C, Hatori M, Keding SR, Semo M, Coffey PJ, Gigg J, Piggins HD, Panda S, Lucas RJ. Melanopsin contributions to irradiance coding in the thalamo-cortical visual system. PLoS Biol. 2010 ; 8: e1000558
7. Butler MP, Silver R. Divergent photic thresholds in the non-image-forming visual system: entrainment, masking and pupillary light reflex. Proc Biol Sci. 2011 ; 278: 745-750
8. Buysse DJ, Browman KE, Monk TH, Reynolds CF, Fasiczka AL, Kupfer DJ. Napping and 24-hour sleep/wake patterns in healthy elderly and young adults. J Am Geriatr Soc. 1992 ; 40: 779-786
9. Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989 ; 28: 193-213 (Pubitemid 19144991)
10. Cajochen C, Munch M, Kobialka S, Krauchi K, Steiner R, Oelhafen P, Orgul S, Wirz-Justice A. High sensitivity of human melatonin, alertness, thermoregulation, and heart rate to short wavelength light. J Clin Endocrinol Metab. 2005 ; 90: 1311-1316 (Pubitemid 40463981)
11. Canver MC, Canver AC, Revere KE, Amado D, Bennett J, Chung DC. Algorithm for pupillometric data analysis. Bioengineering Conference, Proceeding of the 2010 IEEE 36th Annual Northeast 1-2 ; 2010 New York, NY, USA ; 2010..
12. Carrier J, Land S, Buysse DJ, Kupfer DJ, Monk TH. The effects of age and gender on sleep EEG power spectral density in the middle years of life (ages 20-60 years old). Psychophysiology. 2001 ; 38: 232-242 (Pubitemid 32267766)
13. Carrier J, Monk TH, Buysse DJ, Kupfer DJ. Amplitude reduction of the circadian temperature and sleep rhythms in the elderly. Chronobiol Int. 1996 ; 13: 373-386 (Pubitemid 26422799)
14. Carrier J, Monk TH, Buysse DJ, Kupfer DJ. Sleep and morningness- eveningness in the 'middle' years of life (20-59 y). J Sleep Res. 1997 ; 6: 230-237 (Pubitemid 28044146)
15. Chang AM, Scheer FA, Czeisler CA. The human circadian system adapts to prior photic history. J Physiol. 2011 ; 589: 1095-1102
16. Chellappa SL, Steiner R, Blattner P, Oelhafen P, Gotz T, Cajochen C. Non-visual effects of light on melatonin, alertness and cognitive performance: can blue-enriched light keep us alert?. PLoS One. 2011 ; 6: e16429
17. Chen SK, Badea TC, Hattar S. Photoentrainment and pupillary light reflex are mediated by distinct populations of ipRGCs. Nature. 2011 ; 476: 92-95
18. Chylack LT, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY. The Lens Opacities Classification System III: the longitudinal study of the Cataract Study Group. Arch Ophthalmol. 1993 ; 111: 831-836
19. Clarke RJ, Zhang H, Gamlin PD. Characteristics of the pupillary light reflex in the alert rhesus monkey. J Neurophysiol. 2003 ; 89: 3179-3189 (Pubitemid 36682667)
20. Duffy JF, Dijk DJ, Klerman EB, Czeisler CA. Later endogenous circadian temperature nadir relative to an earlier wake time in older people. Am J Physiol. 1998 ; 275: R1478 - R1487
21. Duffy JF, Zeitzer JM, Czeisler CA. Decreased sensitivity to phase-delaying effects of moderate intensity light in older subjects. Neurobiol Aging. 2007 ; 28: 799-807 (Pubitemid 46349347)
22. Ecker JL, Dumitrescu ON, Wong KY, Alam NM, Chen SK, LeGates T, Renna JM, Prusky GT, Berson DM, Hattar S. Melanopsin-expressing retinal ganglion-cell photoreceptors: cellular diversity and role in pattern vision. Neuron. 2010 ; 67: 49-60
23. Freund PR, Watson J, Gilmour GS, Gaillard F, Sauve Y. Differential changes in retina function with normal aging in humans. Doc Ophthalmol. 2011 ; 122: 177-190
24. Gaddy JR, Rollag MD, Brainard GC. Pupil size regulation of threshold of light-induced melatonin suppression. J Clin Endocrinol Metab. 1993 ; 77: 1398-1401 (Pubitemid 23345504)
25. Hatori M, Panda S. The emerging roles of melanopsin in behavioral adaptation to light. Trends Mol Med. 2010 ; 16: 435-446
26. Hebert M, Beattie CW, Tam EM, Yatham LN, Lam RW. Electroretinography in patients with winter seasonal affective disorder. Psychiatry Res. 2004 ; 127: 27-34 (Pubitemid 38916864)
27. Hebert M, Martin SK, Lee C, Eastman CI. The effects of prior light history on the suppression of melatonin by light in humans. J Pineal Res. 2002 ; 33: 198-203 (Pubitemid 35252990)
28. Herljevic M, Middleton B, Thapan K, Skene DJ. Light-induced melatonin suppression: age-related reduction in response to short wavelength light. Exp Gerontol. 2005 ; 40: 237-242 (Pubitemid 40343015)
29. Higuchi S, Ishibashi K, Aritake S, Enomoto M, Hida A, Tamura M, Kozaki T, Motohashi Y, Mishima K. Inter-individual difference in pupil size correlates to suppression of melatonin by exposure to light. Neurosci Lett. 2008 ; 440: 23-26
30. Horne JA, Ostberg O. A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. Int J Chronobiol. 1976 ; 4: 97-110 (Pubitemid 8001177)
31. Hut RA, Oklejewicz M, Rieux C, Cooper HM. Photic sensitivity ranges of hamster pupillary and circadian phase responses do not overlap. J Biol Rhythms. 2008 ; 23: 37-48
32. Jasser SA, Hanifin JP, Rollag MD, Brainard GC. Dim light adaptation attenuates acute melatonin suppression in humans. J Biol Rhythms. 2006 ; 21: 394-404 (Pubitemid 44387430)
33. Jud C, Chappuis S, Revell VL, Sletten TL, Saaltink DJ, Cajochen C, Skene DJ, Albrecht U. Age-dependent alterations in human PER2 levels after early morning blue light exposure. Chronobiol Int. 2009 ; 26: 1462-1469
34. Kawinska A, Dumont M, Selmaoui B, Paquet J, Carrier J. Are modifications of melatonin circadian rhythm in the middle years of life related to habitual patterns of light exposure?. J Biol Rhythms. 2005 ; 20: 451-460 (Pubitemid 41318441)
35. Kergoat H, Kergoat MJ, Justino L. Age-related changes in the flash electroretinogram and oscillatory potentials in individuals age 75 and older. J Am Geriatr Soc. 2001 ; 49: 1212-1217 (Pubitemid 32900149)
36. Kessel L, Lundeman JH, Herbst K, Andersen TV, Larsen M. Age-related changes in the transmission properties of the human lens and their relevance to circadian entrainment. J Cataract Refract Surg. 2010 ; 36: 308-312
37. Kirk RE Experimental Design: Procedures for the Behavioral Sciences. Belmont, CA: Brooks/Cole Publishing Company ; 1968: 146-147.
38. Lockley SW, Brainard GC, Czeisler CA. High sensitivity of the human circadian melatonin rhythm to resetting by short wavelength light. J Clin Endocrinol Metab. 2003 ; 88: 4502-4505 (Pubitemid 37153763)
39. Lockley SW, Evans EE, Scheer FA, Brainard GC, Czeisler CA, Aeschbach D. Short-wavelength sensitivity for the direct effects of light on alertness, vigilance, and the waking electroencephalogram in humans. Sleep. 2006 ; 29: 161-168 (Pubitemid 44019969)
40. McDougal DH, Gamlin PD. The influence of intrinsically-photosensitive retinal ganglion cells on the spectral sensitivity and response dynamics of the human pupillary light reflex. Vision Res. 2010 ; 50: 72-87
41. Monk TH, Buysse DJ, Reynolds CF, Kupfer DJ. Inducing jet lag in an older person: directional asymmetry. Exp Gerontol. 1995 ; 30: 137-145
42. Mure LS, Cornut PL, Rieux C, Drouyer E, Denis P, Gronfier C, Cooper HM. Melanopsin bistability: a fly's eye technology in the human retina. PLoS One. 2009 ; 4: e5991
43. Mure LS, Rieux C, Hattar S, Cooper HM. Melanopsin-dependent nonvisual responses: evidence for photopigment bistability in vivo. J Biol Rhythms. 2007 ; 22: 411-424 (Pubitemid 47507059)
44. Provencio I, Rodriguez IR, Jiang G, Hayes WP, Moreira EF, Rollag MD. A novel human opsin in the inner retina. J Neurosci. 2000 ; 20: 600-605 (Pubitemid 30225562)
45. Revell VL, Skene DJ. Impact of age on human non-visual responses to light. Sleep Biol Rhythms. 2010 ; 8: 84-94
46. Schmidt TM, Chen SK, Hattar S. Intrinsically photosensitive retinal ganglion cells: many subtypes, diverse functions. Trends Neurosci. 2011 ; 34: 572-580
47. Sletten TL, Revell VL, Middleton B, Lederle KA, Skene DJ. Age-related changes in acute and phase-advancing responses to monochromatic light. J Biol Rhythms. 2009 ; 24: 73-84
48. Steer RA, Ball R, Ranieri WF, Beck AT. Further evidence for the construct validity of the Beck Depression Inventory-II with psychiatric outpatients. Psychol Rep. 1997 ; 80: 443-446 (Pubitemid 127461535)
49. Sturr JF, Zhang L, Taub HA, Hannon DJ, Jackowski MM. Psychophysical evidence for losses in rod sensitivity in the aging visual system. Vision Res. 1997 ; 37: 475-481 (Pubitemid 27077866)
50. Turner PL, Van Someren EJ, Mainster MA. The role of environmental light in sleep and health: effects of ocular aging and cataract surgery. Sleep Med Rev. 2010 ; 14: 269-280
51. Vandewalle G, Archer SN, Wuillaume C, Balteau E, Degueldre C, Luxen A, Dijk DJ, Maquet P. Effects of light on cognitive brain responses depend on circadian phase and sleep homeostasis. J Biol Rhythms. 2011 ; 26: 249-259
52. Vandewalle G, Maquet P, Dijk DJ. Light as a modulator of cognitive brain function. Trends Cogn Sci. 2009 ; 13: 429-438
53. West KE, Jablonski MR, Warfield B, Cecil KS, James M, Ayers MA, Maida J, Bowen C, Sliney DH, Rollag MD, et al. Blue light from light-emitting diodes elicits a dose-dependent suppression of melatonin in humans. J Appl Physiol. 2011 ; 110: 619-626
54. Winn B, Whitaker D, Elliott DB, Phillips NJ. Factors affecting light-adapted pupil size in normal human subjects. Invest Ophthalmol Vis Sci. 1994 ; 35: 1132-1137 (Pubitemid 24079848)
55. Wyatt HJ. The human pupil and the use of video-based eyetrackers. Vision Res. 2010 ; 50: 1982-1988