메뉴 건너뛰기




Volumn 26, Issue 6, 2012, Pages 2414-2423

Assessment of circadian rhythms in humans: Comparison of real-time fibroblast reporter imaging with plasma melatonin

Author keywords

Bmal1; Clock genes; Lentivirus; PER3; Sleep

Indexed keywords

CIRCADIAN RHYTHM SIGNALING PROTEIN; FIREFLY LUCIFERASE; MELATONIN; PER3 PROTEIN; PROTEIN BMAL1; TRANSCRIPTION FACTOR ARNTL; UNCLASSIFIED DRUG;

EID: 84861778707     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-201699     Document Type: Article
Times cited : (57)

References (70)
  • 1
    • 50849136513 scopus 로고    scopus 로고
    • Cellular circadian pacemaking and the role of cytosolic rhythms
    • Hastings, M. H., Maywood, E. S., and O'Neill, J. S. (2008) Cellular circadian pacemaking and the role of cytosolic rhythms. Curr. Biol. 18, R805-R815
    • (2008) Curr. Biol. , vol.18
    • Hastings, M.H.1    Maywood, E.S.2    O'Neill, J.S.3
  • 3
    • 33645500010 scopus 로고    scopus 로고
    • Circadian disruption, shift work and the risk of cancer: A summary of the evidence and studies in Seattle
    • Davis, S., and Mirick, D. K. (2006) Circadian disruption, shift work and the risk of cancer: a summary of the evidence and studies in Seattle. Cancer Causes Control 17, 539-545
    • (2006) Cancer Causes Control , vol.17 , pp. 539-545
    • Davis, S.1    Mirick, D.K.2
  • 4
    • 80052940120 scopus 로고    scopus 로고
    • Circadian rhythm sleep disorders
    • Barion, A. (2011) Circadian rhythm sleep disorders. Dis. Mon. 57, 423-437
    • (2011) Dis. Mon. , vol.57 , pp. 423-437
    • Barion, A.1
  • 5
    • 0035966317 scopus 로고    scopus 로고
    • Posttranslational mechanisms regulate the mammalian circadian clock
    • DOI 10.1016/S0092-8674(01)00610-9
    • Lee, C., Etchegaray, J. P., Cagampang, F. R., Loudon, A. S., and Reppert, S. M. (2001) Posttranslational mechanisms regulate the mammalian circadian clock. Cell 107, 855-867 (Pubitemid 34084977)
    • (2001) Cell , vol.107 , Issue.7 , pp. 855-867
    • Lee, C.1    Etchegaray, J.-P.2    Cagampang, F.R.A.3    Loudon, A.S.I.4    Reppert, S.M.5
  • 6
    • 52149109334 scopus 로고    scopus 로고
    • The genetics of mammalian circadian order and disorder: Implications for physiology and disease
    • Takahashi, J. S., Hong, H. K., Ko, C. H., and McDearmon, E. L. (2008) The genetics of mammalian circadian order and disorder: implications for physiology and disease. Nat. Rev. Genet. 9, 764-775
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 764-775
    • Takahashi, J.S.1    Hong, H.K.2    Ko, C.H.3    McDearmon, E.L.4
  • 10
    • 77649108067 scopus 로고    scopus 로고
    • Distinct functions of Period2 and Period3 in the mouse circadian system revealed by in vitro analysis
    • Pendergast, J. S., Friday, R. C., and Yamazaki, S. (2010) Distinct functions of Period2 and Period3 in the mouse circadian system revealed by in vitro analysis. PLoS One 5, e8552
    • (2010) PLoS One , vol.5
    • Pendergast, J.S.1    Friday, R.C.2    Yamazaki, S.3
  • 11
    • 84855664207 scopus 로고    scopus 로고
    • Tissue-specific function of period3 in circadian rhythmicity
    • Pendergast, J. S., Niswender, K. D., and Yamazaki, S. (2012) Tissue-specific function of period3 in circadian rhythmicity. PLoS One 7, e30254
    • (2012) PLoS One , vol.7
    • Pendergast, J.S.1    Niswender, K.D.2    Yamazaki, S.3
  • 12
    • 80053639356 scopus 로고    scopus 로고
    • The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1
    • Lee, H. M., Chen, R., Kim, H., Etchegaray, J. P., Weaver, D. R., and Lee, C. (2011) The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1. Proc. Natl. Acad. Sci. U. S. A. 108, 16451-16456
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 16451-16456
    • Lee, H.M.1    Chen, R.2    Kim, H.3    Etchegaray, J.P.4    Weaver, D.R.5    Lee, C.6
  • 14
    • 0141509017 scopus 로고    scopus 로고
    • Peripheral circadian oscillators in mammals: Time and food
    • DOI 10.1177/0748730403018003007
    • Schibler, U., Ripperger, J., and Brown, S. A. (2003) Peripheral circadian oscillators in mammals: time and food. J. Biol. Rhythms 18, 250-260 (Pubitemid 37187293)
    • (2003) Journal of Biological Rhythms , vol.18 , Issue.3 , pp. 250-260
    • Schibler, U.1    Ripperger, J.2    Brown, S.A.3
  • 15
    • 33745792227 scopus 로고    scopus 로고
    • Suprachiasmatic regulation of circadian rhythms of gene expression in hamster peripheral organs: Effects of transplanting the pacemaker
    • DOI 10.1523/JNEUROSCI.4676-05.2006
    • Guo, H., Brewer, J. M., Lehman, M. N., and Bittman, E. L. (2006) Suprachiasmatic regulation of circadian rhythms of gene expression in hamster peripheral organs: effects of transplanting the pacemaker. J. Neurosci. 26, 6406-6412 (Pubitemid 44318321)
    • (2006) Journal of Neuroscience , vol.26 , Issue.24 , pp. 6406-6412
    • Guo, H.1    Brewer, J.M.2    Lehman, M.N.3    Bittman, E.L.4
  • 16
    • 33750706567 scopus 로고    scopus 로고
    • Properties, entrainment, and physiological functions of mammalian peripheral oscillators
    • DOI 10.1177/0748730406293889
    • Stratmann, M., and Schibler, U. (2006) Properties, entrainment, and physiological functions of mammalian peripheral oscillators. J. Biol. Rhythms 21, 494-506 (Pubitemid 44706830)
    • (2006) Journal of Biological Rhythms , vol.21 , Issue.6 , pp. 494-506
    • Stratmann, M.1    Schibler, U.2
  • 17
    • 0029802108 scopus 로고    scopus 로고
    • Phase-shifting human circadian rhythms: Influence of sleep timing, social contact and light exposure
    • Duffy, J. F., Kronauer, R. E., and Czeisler, C. A. (1996) Phaseshifting human circadian rhythms: influence of sleep timing, social contact and light exposure. J. Physiol. 495(Pt. 1), 289-297 (Pubitemid 26288473)
    • (1996) Journal of Physiology , vol.495 , Issue.1 , pp. 289-297
    • Duffy, J.F.1    Kronauer, R.E.2    Czeisler, C.A.3
  • 18
    • 34250389132 scopus 로고
    • A functional analysis of circadian pacemakers in nocturnal rodents IV, entrainment: Pacemaker as clock
    • Pittendrigh, C. S., and Daan, S. (1976) A functional analysis of circadian pacemakers in nocturnal rodents IV, entrainment: pacemaker as clock. J. Comp. Physiol. 106, 291-331
    • (1976) J. Comp. Physiol. , vol.106 , pp. 291-331
    • Pittendrigh, C.S.1    Daan, S.2
  • 19
    • 0030070965 scopus 로고    scopus 로고
    • Simulations of light effects on the human circadian pacemaker: Implications for assessment of intrinsic period
    • Klerman, E. B., Dijk, D. J., Kronauer, R. E., and Czeisler, C. A. (1996) Simulations of light effects on the human circadian pacemaker: implications for assessment of intrinsic period. Am. J. Physiol. 270, R271-R282
    • (1996) Am. J. Physiol. , vol.270
    • Klerman, E.B.1    Dijk, D.J.2    Kronauer, R.E.3    Czeisler, C.A.4
  • 20
    • 0034203795 scopus 로고    scopus 로고
    • The Colin S. Pittendrigh Lecture. Colin Pittendrigh, Jurgen Aschoff, and the natural entrainment of circadian systems
    • Daan, S. (2000) The Colin S. Pittendrigh Lecture. Colin Pittendrigh, Jurgen Aschoff, and the natural entrainment of circadian systems. J. Biol. Rhythms 15, 195-207
    • (2000) J. Biol. Rhythms , vol.15 , pp. 195-207
    • Daan, S.1
  • 21
    • 0031957186 scopus 로고    scopus 로고
    • Relationship between period and phase angle differences in Mus booduga under abrupt versus gradual light-dark transitions
    • DOI 10.1007/s001140050481
    • Sharma, V. K., Chandrashekaran, M. K., and Singaravel, M. (1998) Relationship between period and phase angle differences in Mus booduga under abrupt versus gradual light-dark transitions. Naturwissenschaften 85, 183-186 (Pubitemid 28217838)
    • (1998) Naturwissenschaften , vol.85 , Issue.4 , pp. 183-186
    • Sharma, V.K.1    Chandrashekaran, M.K.2    Singaravel, M.3
  • 22
    • 0034904284 scopus 로고    scopus 로고
    • Association of intrinsic circadian period with morningness-eveningness, usual wake time, and circadian phase
    • DOI 10.1037
    • Duffy, J. F., Rimmer, D. W., and Czeisler, C. A. (2001) Association of intrinsic circadian period with morningness-eveningness, usual wake time, and circadian phase. Behav. Neurosci. 115, 895-899 (Pubitemid 32738335)
    • (2001) Behavioral Neuroscience , vol.115 , Issue.4 , pp. 895-899
    • Duffy, J.F.1    Rimmer, D.W.2    Czeisler, C.A.3
  • 23
    • 15244349215 scopus 로고    scopus 로고
    • Intrinsic period and light intensity determine the phase relationship between melatonin and sleep in humans
    • DOI 10.1177/0748730404274265
    • Wright, K. P., Jr., Gronfier, C., Duffy, J. F., and Czeisler, C. A. (2005) Intrinsic period and light intensity determine the phase relationship between melatonin and sleep in humans. J. Biol. Rhythms 20, 168-177 (Pubitemid 40389163)
    • (2005) Journal of Biological Rhythms , vol.20 , Issue.2 , pp. 168-177
    • Wright Jr., K.P.1    Gronfier, C.2    Duffy, J.F.3    Czeisler, C.A.4
  • 24
    • 0035136677 scopus 로고    scopus 로고
    • An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome
    • DOI 10.1126/science.1057499
    • Toh, K. L., Jones, C. R., He, Y., Eide, E. J., Hinz, W. A., Virshup, D. M., Ptacek, L. J., and Fu, Y. H. (2001) An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science 291, 1040-1043 (Pubitemid 32157412)
    • (2001) Science , vol.291 , Issue.5506 , pp. 1040-1043
    • Toh, K.L.1    Jones, C.R.2    He, Y.3    Eide, E.J.4    Hinz, W.A.5    Virshup, D.M.6    Ptacek, L.J.7    Fu, Y.-H.8
  • 25
    • 15844420887 scopus 로고    scopus 로고
    • Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome
    • DOI 10.1038/nature03453
    • Xu, Y., Padiath, Q. S., Shapiro, R. E., Jones, C. R., Wu, S. C., Saigoh, N., Saigoh, K., Ptacek, L. J., and Fu, Y. H. (2005) Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome. Nature 434, 640-644 (Pubitemid 40488555)
    • (2005) Nature , vol.434 , Issue.7033 , pp. 640-644
    • Xu, Y.1    Padiath, Q.S.2    Shapiro, R.E.3    Jones, C.R.4    Wu, S.C.5    Saigoh, N.6    Saigoh, K.7    Ptacek, L.J.8    Fu, Y.-H.9
  • 26
    • 0036178045 scopus 로고    scopus 로고
    • Control of intracellular dynamics of mammalian period proteins by casein kinase I ε (CKIε) and CKIdelta in cultured cells
    • DOI 10.1128/MCB.22.6.1693-1703.2002
    • Akashi, M., Tsuchiya, Y., Yoshino, T., and Nishida, E. (2002) Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells. Mol. Cell. Biol. 22, 1693-1703 (Pubitemid 34174987)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.6 , pp. 1693-1703
    • Akashi, M.1    Tsuchiya, Y.2    Yoshino, T.3    Nishida, E.4
  • 27
    • 3543005291 scopus 로고    scopus 로고
    • Identification of mPer1 phosphorylation sites responsible for the nuclear entry
    • DOI 10.1074/jbc.M403433200
    • Takano, A., Isojima, Y., and Nagai, K. (2004) Identification of mPer1 phosphorylation sites responsible for the nuclear entry. J. Biol. Chem. 279, 32578-32585 (Pubitemid 39014714)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.31 , pp. 32578-32585
    • Takano, A.1    Isojima, Y.2    Nagai, K.3
  • 29
    • 22544470876 scopus 로고    scopus 로고
    • Nuclear import of mPER3 in Xenopus oocytes and HeLa cells requires complex formation with mPER1
    • DOI 10.1111/j.1742-4658.2005.04798.x
    • Loop, S., and Pieler, T. (2005) Nuclear import of mPER3 in Xenopus oocytes and HeLa cells requires complex formation with mPER1. FEBS J. 272, 3714-3724 (Pubitemid 41021182)
    • (2005) FEBS Journal , vol.272 , Issue.14 , pp. 3714-3724
    • Loop, S.1    Pieler, T.2
  • 32
    • 0141743929 scopus 로고    scopus 로고
    • A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference
    • Archer, S. N., Robilliard, D. L., Skene, D. J., Smits, M., Williams, A., Arendt, J., and von Schantz, M. (2003) A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. Sleep 26, 413-415 (Pubitemid 39610658)
    • (2003) Sleep , vol.26 , Issue.4 , pp. 413-415
    • Archer, S.N.1    Robilliard, D.L.2    Skene, D.J.3    Smits, M.4    Williams, A.5    Arendt, J.6    Von Schantz, M.7
  • 34
    • 17244371789 scopus 로고    scopus 로고
    • Association of the length polymorphism in the human Per3 gene with the delayed sleep-phase syndrome: Does latitude have an influence upon it?
    • Pereira, D. S., Tufik, S., Louzada, F. M., Benedito-Silva, A. A., Lopez, A. R., Lemos, N. A., Korczak, A. L., D'Almeida, V., and Pedrazzoli, M. (2005) Association of the length polymorphism in the human Per3 gene with the delayed sleep-phase syndrome: does latitude have an influence upon it? Sleep 28, 29-32 (Pubitemid 40543117)
    • (2005) Sleep , vol.28 , Issue.1 , pp. 29-32
    • Pereira, D.S.1    Tufik, S.2    Louzada, F.M.3    Benedito-Silva, A.A.4    Lopez, A.R.5    Lemos, N.A.6    Korczak, A.L.7    D'Almeida, V.8    Pedrazzoli, M.9
  • 35
    • 77951721048 scopus 로고    scopus 로고
    • Polymorphism in the PER3 promoter associates with diurnal preference and delayed sleep phase disorder
    • Archer, S. N., Carpen, J. D., Gibson, M., Lim, G. H., Johnston, J. D., Skene, D. J., and von Schantz, M. (2010) Polymorphism in the PER3 promoter associates with diurnal preference and delayed sleep phase disorder. Sleep 33, 695-701
    • (2010) Sleep , vol.33 , pp. 695-701
    • Archer, S.N.1    Carpen, J.D.2    Gibson, M.3    Lim, G.H.4    Johnston, J.D.5    Skene, D.J.6    Von Schantz, M.7
  • 36
    • 84856868021 scopus 로고    scopus 로고
    • Sleep, diurnal preference, health and psychological well-being: A prospective single-allelic-variation study
    • Lazar, A. S., Slak, A., Lo, J. C., Santhi, N., von Schantz, M., Archer, S. N., Groeger, J. A., and Dijk, D. J. (2012) Sleep, diurnal preference, health and psychological well-being: A prospective single-allelic-variation study. Chronobiol. Int. 29, 131-146
    • (2012) Chronobiol. Int. , vol.29 , pp. 131-146
    • Lazar, A.S.1    Slak, A.2    Lo, J.C.3    Santhi, N.4    Von Schantz, M.5    Archer, S.N.6    Groeger, J.A.7    Dijk, D.J.8
  • 37
    • 0033847103 scopus 로고    scopus 로고
    • Targeted disruption of the mPer3 gene: Subtle effects on circadian clock function
    • DOI 10.1128/MCB.20.17.6269-6275.2000
    • Shearman, L. P., Jin, X., Lee, C., Reppert, S. M., and Weaver, D. R. (2000) Targeted disruption of the mPer3 gene: subtle effects on circadian clock function. Mol. Cell. Biol. 20, 6269-6275 (Pubitemid 30650213)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.17 , pp. 6269-6275
    • Shearman, L.P.1    Jin, X.2    Lee, C.3    Reppert, S.M.4    Weaver, D.R.5
  • 38
    • 77949410784 scopus 로고    scopus 로고
    • Light-dependent behavioral phenotypes in PER3-deficient mice
    • Van der Veen, D. R., and Archer, S. N. (2010) Light-dependent behavioral phenotypes in PER3-deficient mice. J. Biol. Rhythms 25, 3-8
    • (2010) J. Biol. Rhythms , vol.25 , pp. 3-8
    • Van Der Veen, D.R.1    Archer, S.N.2
  • 39
    • 33947635005 scopus 로고    scopus 로고
    • PER3 Polymorphism Predicts Sleep Structure and Waking Performance
    • DOI 10.1016/j.cub.2007.01.073, PII S096098220700992X
    • Viola, A. U., Archer, S. N., James, L. M., Groeger, J. A., Lo, J. C., Skene, D. J., von Schantz, M., and Dijk, D. J. (2007) PER3 polymorphism predicts sleep structure and waking performance. Curr. Biol. 17, 613-618 (Pubitemid 46497792)
    • (2007) Current Biology , vol.17 , Issue.7 , pp. 613-618
    • Viola, A.U.1    Archer, S.N.2    James, L.M.3    Groeger, J.A.4    Lo, J.C.Y.5    Skene, D.J.6    Von, S.M.7    Dijk, D.-J.8
  • 40
    • 43749106278 scopus 로고    scopus 로고
    • Inter-individual differences in habitual sleep timing and entrained phase of endogenous circadian rhythms of BMAL1, PER2 and PER3 mRNA in human leukocytes
    • Archer, S. N., Viola, A. U., Kyriakopoulou, V., von Schantz, M., and Dijk, D. J. (2008) Inter-individual differences in habitual sleep timing and entrained phase of endogenous circadian rhythms of BMAL1, PER2 and PER3 mRNA in human leukocytes. Sleep 31, 608-617 (Pubitemid 351694249)
    • (2008) Sleep , vol.31 , Issue.5 , pp. 608-617
    • Archer, S.N.1    Viola, A.U.2    Kyriakopoulou, V.3    Von Schantz, M.4    Dijk, D.-J.5
  • 41
    • 77950866154 scopus 로고    scopus 로고
    • PERIOD3, circadian phenotypes, and sleep homeostasis
    • Dijk, D. J., and Archer, S. N. (2010) PERIOD3, circadian phenotypes, and sleep homeostasis. Sleep Med. Rev. 14, 151-160
    • (2010) Sleep Med. Rev. , vol.14 , pp. 151-160
    • Dijk, D.J.1    Archer, S.N.2
  • 43
    • 0001407680 scopus 로고
    • Circadian rhythms in man
    • Aschoff, J. (1965) Circadian rhythms in man. Science 148, 1427-1432
    • (1965) Science , vol.148 , pp. 1427-1432
    • Aschoff, J.1
  • 44
    • 0018862549 scopus 로고
    • Distribution of REM sleep on a 90 minute sleep-wake schedule
    • Carskadon, M. A., and Dement, W. C. (1980) Distribution of REM sleep on a 90 minute sleep-wake schedule. Sleep 2, 309-317 (Pubitemid 10086294)
    • (1980) Sleep , vol.2 , Issue.3 , pp. 309-317
    • Carskadon, M.A.1    Dement, W.C.2
  • 47
    • 0020629514 scopus 로고
    • Different types of melatonin circadian secretory rhythms in some blind subjects
    • Lewy, A. J., and Newsome, D. A. (1983) Different types of melatonin circadian secretory rhythms in some blind subjects. J. Clin. Endocrinol. Metab. 56, 1103-1107 (Pubitemid 13055100)
    • (1983) Journal of Clinical Endocrinology and Metabolism , vol.56 , Issue.6 , pp. 1103-1107
    • Lewy, A.J.1    Newsome, D.A.2
  • 55
    • 33846944676 scopus 로고    scopus 로고
    • System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock
    • Kornmann, B., Schaad, O., Bujard, H., Takahashi, J. S., and Schibler, U. (2007) System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock. PLoS Biol. 5, e34
    • (2007) PLoS Biol. , vol.5
    • Kornmann, B.1    Schaad, O.2    Bujard, H.3    Takahashi, J.S.4    Schibler, U.5
  • 58
    • 67649321886 scopus 로고    scopus 로고
    • Functional magnetic resonance imaging-assessed brain responses during an executive task depend on interaction of sleep homeostasis, circadian phase, and PER3 genotype
    • Vandewalle, G., Archer, S. N., Wuillaume, C., Balteau, E., Degueldre, C., Luxen, A., Maquet, P., and Dijk, D. J. (2009) Functional magnetic resonance imaging-assessed brain responses during an executive task depend on interaction of sleep homeostasis, circadian phase, and PER3 genotype. J. Neurosci. 29, 7948-7956
    • (2009) J. Neurosci. , vol.29 , pp. 7948-7956
    • Vandewalle, G.1    Archer, S.N.2    Wuillaume, C.3    Balteau, E.4    Degueldre, C.5    Luxen, A.6    Maquet, P.7    Dijk, D.J.8
  • 59
    • 0029056609 scopus 로고
    • Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans
    • Dijk, D. J., and Czeisler, C. A. (1995) Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans. J. Neurosci. 15, 3526-3538
    • (1995) J. Neurosci. , vol.15 , pp. 3526-3538
    • Dijk, D.J.1    Czeisler, C.A.2
  • 60
  • 61
    • 0036548609 scopus 로고    scopus 로고
    • Comparisons of the variability of three markers of the human circadian pacemaker
    • DOI 10.1177/074873002129002474
    • Klerman, E. B., Gershengorn, H. B., Duffy, J. F., and Kronauer, R. E. (2002) Comparisons of the variability of three markers of the human circadian pacemaker. J. Biol. Rhythms 17, 181-193 (Pubitemid 37187358)
    • (2002) Journal of Biological Rhythms , vol.17 , Issue.2 , pp. 181-193
    • Klerman, E.B.1    Gershengorn, H.B.2    Duffy, J.F.3    Kronauer, R.E.4
  • 69
    • 0028904194 scopus 로고
    • Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms
    • Welsh, D. K., Logothetis, D. E., Meister, M., and Reppert, S. M. (1995) Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 14, 697-706
    • (1995) Neuron , vol.14 , pp. 697-706
    • Welsh, D.K.1    Logothetis, D.E.2    Meister, M.3    Reppert, S.M.4
  • 70
    • 84858341982 scopus 로고    scopus 로고
    • Interindividual differences in circadian rhythmicity and sleep homeostasis in older people: Effect of a PER3 polymorphism
    • E-pub ahead of print doi: 10.1016/j.neurobiolaging.2011.10.024
    • Viola, A. U., Chellappa, S. L., Archer, S. N., Pugin, F., Gotz, T., Dijk, D. J., and Cajochen, C. (2011) Interindividual differences in circadian rhythmicity and sleep homeostasis in older people: effect of a PER3 polymorphism. [E-pub ahead of print] Neurobiol. Aging doi: 10.1016/j. neurobiolaging.2011.10.024
    • (2011) Neurobiol. Aging
    • Viola, A.U.1    Chellappa, S.L.2    Archer, S.N.3    Pugin, F.4    Gotz, T.5    Dijk, D.J.6    Cajochen, C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.