Extracellular low pH affects circadian rhythm expression in human primary fibroblasts

Biochemical and Biophysical Research Communications

Volumn 416, Issue 3-4, 2011, Pages 337-342

  Lee, Sang Kil ^a   Achieng, Elsie ^a   Maddox, Connie ^a   Chen, Suephy C ^b,c   Iuvone, P Michael ^b   Fukuhara, Chiaki ^a  

^a MOREHOUSE SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Circadian rhythm; Human primary skin fibroblast; Period; Peripheral oscillator; PH; Real time bioluminescence monitoring

Indexed keywords

LUCIFERASE; PROTEIN BMAL1;

ADULT; ARTICLE; CELL CULTURE; CELL STRUCTURE; CELL VIABILITY; CIRCADIAN RHYTHM; CULTURE MEDIUM; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NORMAL HUMAN; PH; PRIORITY JOURNAL; SKIN FIBROBLAST;

ARNTL TRANSCRIPTION FACTORS; CELL SURVIVAL; CELLS, CULTURED; CIRCADIAN RHYTHM; FIBROBLASTS; GENES, REPORTER; HUMANS; HYDROGEN-ION CONCENTRATION; LUCIFERASES; PERIOD CIRCADIAN PROTEINS; SKIN;

EID: 84855908834     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.11.037     Document Type: Article

References (19)

1. Ko C.H., Takahashi J.S. Molecular components of the mammalian circadian clock. Hum. Mol. Genet. 2006, 15:271-277.
2. Fukuhara C., Tosini G. Peripheral circadian oscillators and their rhythmic regulation. Front Biosci. 2003, 8:642-651.
3. Chansard M., Mlyneux P., Nomura K., Harrington M.E., Fukuhara C. C-Jun N-terminal kinase inhibitor SP600125 modulates the period of mammalian circadian rhythms. Neuroscience 2007, 145:812-823.
4. Brown S.A., Fleury-Olela F., Nagoshi E., et al. The period length of fibroblast circadian rhythm gene expression varies widely among human individuals. PLoS Biol. 2005, 3:1813-1818.
5. Nomura K., Castanon-Cervantes O., Davidson A., Fukuhara C. Selective serotonin reuptake inhibitors and raft inhibitors shorten the period of Period1-driven bioluminescence rhythms in rat-1 fibroblasts. Life Sci. 2008, 82:1169-1174.
6. Cobbe S.M., Poole-Wilson P.A. The time of onset and severity of acidosis in myocardial ischaemia. J. Mol. Cell Cardiol. 1980, 12:745-760.
7. Maury E., Ramsey K.M., Bass J. Circadian rhythms and metabolic syndrome: from experimental genetics to human disease. Circ. Res. 2010, 106:447-462.
8. J.W. Wojtkowiak, D. Verduzco, K. Schramm, R.J. Gillies, Drug resistance and cellular adaptation to tumor acidic pH microenvironment, Mol. Pharm. 2011 Oct 7 [Epub ahead of print].
9. Fukuhara C., Dirden J.C., Tosini G. Analysis of gene expression following norepinephrine stimulation in the rat pineal gland using DNA microarray technique. J. Pin. Res. 2003, 35:196-203.
10. Xu Z., Ford G.D., Croslan D.R., Jiang J., Gates A., Allen R., Ford B.D. Neuroprotection by neuregulin-1 following focal stroke is associated with the attenuation of ischemia-induced pro-inflammatory and stress gene expression. Neurobiol. Dis. 2005, 19:461-470.
11. Ford G.D., Ford B.D., Steele E.C., Gates A., Hood D., Matthews M.A., Mirza S., Macleish P.R. Analysis of transcriptional profiles and functional clustering of global cerebellar gene expression in PCD3J mice. Biochem. Biophys. Res. Commun. 2008, 377:556-561.
12. Fukuhara C., Tosini G. Analysis of daily and circadian gene expression in the rat pineal gland. Neurosci. Res. 2008, 60:192-198.
13. Curto E.V., Lambert G.W., Davis R.L., Wilborn T.W., Dooley T.P. Biomarkers of human skin cells identified using DermArray DNA arrays and new bioinformatics methods. Biochem. Biophys. Res. Commun. 2002, 291:1052-1064.
14. Sorrell J.M., Caplan A.I. Fibroblast heterogeneity: more than skin deep. J. Cell Sci. 2004, 117:667-675.
15. Zungu I.L., Evans D.H., Houreld N., Abrahamse H. Biological responses of injured human skin fibroblasts to assess the efficacy of in vitro models for cell stress studies. African J. Biochem. Res. 2007, 1:60-71.
16. Ceccarine C., Eagle H. pH as a determinant of cellular growth and contact inhibition. Proc. Nat. Acad. Sci. USA 1971, 68:229-233.
17. West D.J. Effect of pH and biotin on a circadian rhythm of conidiation in Neurospora crassa. J. Bacteriol. 1975, 123:387-389.
18. Ruoff P., Behzadi A., Hauglid M., Vinsjevik M., Havas H. PH homeostasis of the circadian sporulation rhythm in clock mutants of Neurospora Crassa. Chronobiol. Int. 2000, 17:733-750.
19. Khalsa S.B., Ralph M.R., Block G.D. Does low intercellular pH stop the motion of the Bulla circadian pacemaker?. J. Neurosci. 1991, 1:2672-2679.