Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia

FASEB Journal

Volumn 26, Issue 6, 2012, Pages 2424-2436

  Weber, Martina ^a   Lambeck, Sandro ^a   Ding, Nadine ^b   Henken, Stefanie ^b   Kohl, Matthias ^a   Deigner, Hans P ^c   Enot, David P ^c   Igwe, Emeka I ^c   Frappart, Lucien ^d   Kiehntopf, Michael ^a   Claus, Ralf A ^a   Kamradt, Thomas ^a   Weih, Debra ^e   Vodovotz, Yoram ^f,g   Briles, David E ^h   Ogunniyi, Abiodun D ⁱ   Paton, James C ⁱ   Maus, Ulrich A ^b   Bauer, Michael ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c BIOCRATES LIFE SCIENCES AG   (Austria)

^d UNIVERSITÉ LYON 1   (France)

^e FRITZ LIPMANN INSTITUTE   (Germany)

^f UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^g MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

^h University of Alabama at Birmingham   (United States)

ⁱ UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Pathogen host interaction; Pneumolysin; Sepsis

Indexed keywords

ACETOACETATE COENZYME A LIGASE; AMYLOID P COMPONENT; CALCITONIN RECEPTOR LIKE; CALPONIN 2; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; COMPLEMENT COMPONENT RECEPTOR 2; CXCL9 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GERANYLTRANSFERASE; HIPPOCALCIN LIKE 1; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NUCLEAR RECEPTOR COACTIVATOR 4; OROSOMUCOID 2; OSTEOGLYCIN; PHOSPHODIESTERASE 5A; PHOSPHOLIPID SCRAMBLASE 1; PNEUMOLYSIN; PROTEIN; RINGER FINGER PROTEIN 123; SOLUTE CARRIER FAMILY 7 MEMBER 10; STAT1 PROTEIN; STAT2 PROTEIN; STEROL C5 DESATURASE; THROMBOMODULIN; TSUKUSHIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; COLONY FORMING UNIT; DISEASE SEVERITY; GENE EXPRESSION; HEMOLYSIS; HYPERCHOLESTEROLEMIA; LIVER; LUNG; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MASS SPECTROMETRY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEROTYPE; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; BACTERIAL PROTEINS; CHOLESTEROL; FEMALE; LIVER; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; PNEUMONIA, PNEUMOCOCCAL; PROTEIN ARRAY ANALYSIS; STREPTOLYSINS;

MUS; STREPTOCOCCUS PNEUMONIAE;

EID: 84861777724     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-191957     Document Type: Article

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