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Volumn 51, Issue 10, 2012, Pages 1177-1182

Effect of rosuvastatin on ROCK activity, endothelial function, and inflammation in Asian patients with atherosclerosis

Author keywords

Cholesterol; Endothelial; Inflammation atherosclerosis; Rho; Rho kinase; Rosuvastatin

Indexed keywords

C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MYOSIN; RHO KINASE; ROSUVASTATIN; TRIACYLGLYCEROL;

EID: 84861758609     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.51.6771     Document Type: Article
Times cited : (12)

References (33)
  • 1
    • 33947716172 scopus 로고    scopus 로고
    • Endothelial function and dysfunction: Testing and clinical relevance
    • Deanfield JE, Halcox JP, Rabelink TJ. Endothelial function and dysfunction: testing and clinical relevance. Circulation 115: 1285-1295, 2007.
    • (2007) Circulation , vol.115 , pp. 1285-1295
    • Deanfield, J.E.1    Halcox, J.P.2    Rabelink, T.J.3
  • 2
    • 61449123110 scopus 로고    scopus 로고
    • Influence of short-term rosuvastatin therapy on endothelial progenitor cells and endothelial function
    • Pirro M, Schillaci G, Romagno PF, et al. Influence of short-term rosuvastatin therapy on endothelial progenitor cells and endothelial function. J Cardiovasc Pharmacol Ther 14: 14-21, 2009.
    • (2009) J Cardiovasc Pharmacol Ther , vol.14 , pp. 14-21
    • Pirro, M.1    Schillaci, G.2    Romagno, P.F.3
  • 3
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein JL, Brown MS. Regulation of the mevalonate pathway. Nature 343: 425-430, 1990.
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 4
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomized trials of statins
    • Baigent CA, Keech PM, Kearney L, et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomized trials of statins. Lancet 366: 1267-1278, 2005.
    • (2005) Lancet , vol.366 , pp. 1267-1278
    • Baigent, C.A.1    Keech, P.M.2    Kearney, L.3
  • 5
    • 0035572718 scopus 로고    scopus 로고
    • Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
    • Takemoto M, Liao JK. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 21: 1712-1719, 2001.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1712-1719
    • Takemoto, M.1    Liao, J.K.2
  • 6
    • 0030968580 scopus 로고    scopus 로고
    • Rho GTPases and signaling networks
    • Van Aelst L, D'Souza-Schorey C. Rho GTPases and signaling networks. Genes Dev 11: 2295-2322, 1997.
    • (1997) Genes Dev , vol.11 , pp. 2295-2322
    • van Aelst, L.1    D'Souza-Schorey, C.2
  • 7
    • 59049103155 scopus 로고    scopus 로고
    • Evidence for statin pleiotropy in humans: Differential effects of statins and ezetimibe on rhoassociated coiled-coil containing protein kinase activity, endothelial function, and inflammation
    • Liu PY, Liu YW, Lin LJ, et al. Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rhoassociated coiled-coil containing protein kinase activity, endothelial function, and inflammation. Circulation 119: 131-138, 2009.
    • (2009) Circulation , vol.119 , pp. 131-138
    • Liu, P.Y.1    Liu, Y.W.2    Lin, L.J.3
  • 8
    • 0032508533 scopus 로고    scopus 로고
    • Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase
    • Laufs U, Liao JK. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. J Biol Chem 273: 24266-24271, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 24266-24271
    • Laufs, U.1    Liao, J.K.2
  • 9
    • 0038338555 scopus 로고    scopus 로고
    • Nitric oxide-induced decrease in calcium sensitivity of resistance arteries is attributable to activation of the myosin light chain phosphatase and antagonized by the RhoA/Rho kinase pathway
    • Bolz SS, Vogel L, Sollinger D, et al. Nitric oxide-induced decrease in calcium sensitivity of resistance arteries is attributable to activation of the myosin light chain phosphatase and antagonized by the RhoA/Rho kinase pathway. Circulation 107: 3081-3087, 2003.
    • (2003) Circulation , vol.107 , pp. 3081-3087
    • Bolz, S.S.1    Vogel, L.2    Sollinger, D.3
  • 10
    • 0035997530 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors reduce interleukin-6 synthesis in human vascular smooth muscle cells
    • Ito T, Ikeda U, Shimpo M, et al. HMG-CoA reductase inhibitors reduce interleukin-6 synthesis in human vascular smooth muscle cells. Cardiovasc Drugs Ther 16: 121-126, 2002.
    • (2002) Cardiovasc Drugs Ther , vol.16 , pp. 121-126
    • Ito, T.1    Ikeda, U.2    Shimpo, M.3
  • 11
    • 4644275746 scopus 로고    scopus 로고
    • Clinical efficacy and safety of rosuvastatin in Japanese patients with heterozygous familial hypercholesterolemia
    • Mabuchi H, Nohara A, Higashikata T, et al. Clinical efficacy and safety of rosuvastatin in Japanese patients with heterozygous familial hypercholesterolemia. J Atheroscler Thromb 11: 152-158, 2004.
    • (2004) J Atheroscler Thromb , vol.11 , pp. 152-158
    • Mabuchi, H.1    Nohara, A.2    Higashikata, T.3
  • 12
    • 34848822177 scopus 로고    scopus 로고
    • Effect of rosuvastatin 5-20 mg on triglycerides and other lipid parameters in Japanese patients with hypertriglyceridemia
    • Saito Y, Yamada N, Shirai K, et al. Effect of rosuvastatin 5-20 mg on triglycerides and other lipid parameters in Japanese patients with hypertriglyceridemia. Atherosclerosis 194: 505-511, 2007.
    • (2007) Atherosclerosis , vol.194 , pp. 505-511
    • Saito, Y.1    Yamada, N.2    Shirai, K.3
  • 13
    • 59049108097 scopus 로고    scopus 로고
    • Comparison of effects of rosuvastatin (10 mg) versus atorvastatin (40 mg) on Rho kinase activity in Caucasian men with a previous atherosclerotic event
    • Rawlings R, Nohria A, Liu PY, et al. Comparison of effects of rosuvastatin (10 mg) versus atorvastatin (40 mg) on Rho kinase activity in Caucasian men with a previous atherosclerotic event. Am J Cardiol 103: 437-441, 2009.
    • (2009) Am J Cardiol , vol.103 , pp. 437-441
    • Rawlings, R.1    Nohria, A.2    Liu, P.Y.3
  • 14
    • 0031754706 scopus 로고    scopus 로고
    • Analytical evaluation of particle-enhanced immunonephelometric assays for C-reactive protein, serum amyloid A and mannosebinding protein in human serum
    • Ledue TB, Weiner DL, Sipe JD, Poulin SE, Collins MF, Rifai N. Analytical evaluation of particle-enhanced immunonephelometric assays for C-reactive protein, serum amyloid A and mannosebinding protein in human serum. Ann Clin Biochem 35: 745-753, 1998.
    • (1998) Ann Clin Biochem , vol.35 , pp. 745-753
    • Ledue, T.B.1    Weiner, D.L.2    Sipe, J.D.3    Poulin, S.E.4    Collins, M.F.5    Rifai, N.6
  • 15
    • 67650902217 scopus 로고    scopus 로고
    • Statins inhibit Rho kinase activity in patients with atherosclerosis
    • Nohria A, Prsic A, Liu PY, et al. Statins inhibit Rho kinase activity in patients with atherosclerosis. Atherosclerosis 205: 517-521, 2009.
    • (2009) Atherosclerosis , vol.205 , pp. 517-521
    • Nohria, A.1    Prsic, A.2    Liu, P.Y.3
  • 16
    • 0033615977 scopus 로고    scopus 로고
    • Phosphorylation of myosinbinding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo
    • Kawano Y, Fukata Y, Oshiro N, et al. Phosphorylation of myosinbinding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. J Cell Biol 147: 1023-1038, 1999.
    • (1999) J Cell Biol , vol.147 , pp. 1023-1038
    • Kawano, Y.1    Fukata, Y.2    Oshiro, N.3
  • 17
    • 19944430327 scopus 로고    scopus 로고
    • Endothelial function and dysfunction. Part I: Methodological issues for assessment in the different vascular beds: A statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension
    • Deanfield J, Donald A, Ferri C, et al. Endothelial function and dysfunction. Part I: Methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension. J Hypertens 23: 7-17, 2005.
    • (2005) J Hypertens , vol.23 , pp. 7-17
    • Deanfield, J.1    Donald, A.2    Ferri, C.3
  • 18
    • 6044236710 scopus 로고    scopus 로고
    • Randomized doseresponse study of Rosuvastatin in Japanese patients with hypercholesterolemia
    • Saito Y, Goto Y, Dane A, Strutt K, Raza A. Randomized doseresponse study of Rosuvastatin in Japanese patients with hypercholesterolemia. J Atheroscler Thromb 10: 329-336, 2003.
    • (2003) J Atheroscler Thromb , vol.10 , pp. 329-336
    • Saito, Y.1    Goto, Y.2    Dane, A.3    Strutt, K.4    Raza, A.5
  • 19
    • 0037223771 scopus 로고    scopus 로고
    • Comparative effects of Rosuvastatin and Atorvastatin across their dose range in patients with hypercholesterolemia and without active arterial disease
    • Schneck DW, Knopp RH, Ballantyne CM, et al. Comparative effects of Rosuvastatin and Atorvastatin across their dose range in patients with hypercholesterolemia and without active arterial disease. Am J Cardiol 91: 33-41, 2003.
    • (2003) Am J Cardiol , vol.91 , pp. 33-41
    • Schneck, D.W.1    Knopp, R.H.2    Ballantyne, C.M.3
  • 20
    • 2942720515 scopus 로고    scopus 로고
    • Beneficial cardiovascular pleiotropic effects of statins
    • Davignon J. Beneficial cardiovascular pleiotropic effects of statins. Circulation 109: 39-43, 2004.
    • (2004) Circulation , vol.109 , pp. 39-43
    • Davignon, J.1
  • 21
    • 33646740966 scopus 로고    scopus 로고
    • Differential effects of short-term lipid lowering with ezetimibe and statins on endothelial function in patients with CAD: Clinical evidence for "pleiotropic" functions of statin therapy
    • Fichtlscherer S, Schmidt-Lucke C, Bojunga S, et al. Differential effects of short-term lipid lowering with ezetimibe and statins on endothelial function in patients with CAD: clinical evidence for "pleiotropic" functions of statin therapy. Eur Heart J 27: 1182-1190, 2006.
    • (2006) Eur Heart J , vol.27 , pp. 1182-1190
    • Fichtlscherer, S.1    Schmidt-Lucke, C.2    Bojunga, S.3
  • 22
    • 33847404392 scopus 로고    scopus 로고
    • Treatment with ezetimibe plus low-dose atorvastatin compared with higher-dose atorvastatin alone: Is sufficient cholesterol-lowering enough to inhibit platelets?
    • Piorkowski M, Fischer S, Stellbaum C, et al. Treatment with ezetimibe plus low-dose atorvastatin compared with higher-dose atorvastatin alone: is sufficient cholesterol-lowering enough to inhibit platelets? J Am Coll Cardiol 49: 1035-1042, 2007.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1035-1042
    • Piorkowski, M.1    Fischer, S.2    Stellbaum, C.3
  • 23
    • 77956497988 scopus 로고    scopus 로고
    • Pleiotropic effects of statins in atherosclerotic disease
    • Pasterkamp G, van Lammeren GW. Pleiotropic effects of statins in atherosclerotic disease. Cardiovasc Ther 8: 1235-1237, 2010.
    • (2010) Cardiovasc Ther , vol.8 , pp. 1235-1237
    • Pasterkamp, G.1    van Lammeren, G.W.2
  • 24
    • 33746823739 scopus 로고    scopus 로고
    • Rho-kinase: A potential link between hypercholesterolemia and abnormal vascular smooth muscle contraction
    • Liao JK. Rho-kinase: a potential link between hypercholesterolemia and abnormal vascular smooth muscle contraction. Circ Res 99: 238-239, 2006.
    • (2006) Circ Res , vol.99 , pp. 238-239
    • Liao, J.K.1
  • 25
    • 0032584177 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
    • Laufs U, La Fata V, Plutzky J, Liao JK. Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation 97: 1129-1135, 1998.
    • (1998) Circulation , vol.97 , pp. 1129-1135
    • Laufs, U.1    la Fata, V.2    Plutzky, J.3    Liao, J.K.4
  • 26
    • 43049136576 scopus 로고    scopus 로고
    • ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury
    • Noma K, Rikitake Y, Oyama N, et al. ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury. J Clin Invest 118: 1632-1644, 2008.
    • (2008) J Clin Invest , vol.118 , pp. 1632-1644
    • Noma, K.1    Rikitake, Y.2    Oyama, N.3
  • 27
    • 0033527623 scopus 로고    scopus 로고
    • Cell migration-movin' on
    • Horwitz AR, Parsons JT. Cell migration-movin' on. Science 286: 1102-1103, 1999.
    • (1999) Science , vol.286 , pp. 1102-1103
    • Horwitz, A.R.1    Parsons, J.T.2
  • 28
    • 0036645303 scopus 로고    scopus 로고
    • Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase
    • Takemoto M, Sun J, Hiroki J, Shimokawa H, Liao JK. Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase. Circulation 106: 57-62, 2002.
    • (2002) Circulation , vol.106 , pp. 57-62
    • Takemoto, M.1    Sun, J.2    Hiroki, J.3    Shimokawa, H.4    Liao, J.K.5
  • 29
    • 0036892061 scopus 로고    scopus 로고
    • Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells
    • Ming XF, Viswambharan H, Barandier C, et al. Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells. Mol Cell Biol 22: 8467-8477, 2002.
    • (2002) Mol Cell Biol , vol.22 , pp. 8467-8477
    • Ming, X.F.1    Viswambharan, H.2    Barandier, C.3
  • 30
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 420: 868-874, 2002.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 31
    • 0037469179 scopus 로고    scopus 로고
    • Coming of age of C-reactive protein: Using inflammation markers in cardiology
    • Yeh ET, Willerson JT. Coming of age of C-reactive protein: using inflammation markers in cardiology. Circulation 107: 370-371, 2003.
    • (2003) Circulation , vol.107 , pp. 370-371
    • Yeh, E.T.1    Willerson, J.T.2
  • 32
    • 26244451415 scopus 로고    scopus 로고
    • Rho/Rho-kinase pathway contributes to C-reactive protein-induced plasminogen activator inhibitor-1 expression in endothelial cells
    • Nakakuki T, Ito M, Iwasaki H, et al. Rho/Rho-kinase pathway contributes to C-reactive protein-induced plasminogen activator inhibitor-1 expression in endothelial cells. Arterioscler Thromb Vasc Biol 25: 2088-2093, 2005.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2088-2093
    • Nakakuki, T.1    Ito, M.2    Iwasaki, H.3
  • 33
    • 56749106312 scopus 로고    scopus 로고
    • Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
    • Ridker PM, Danielson E, Fonseca FAH, et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 359: 2195-2207, 2008.
    • (2008) N Engl J Med , vol.359 , pp. 2195-2207
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.