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Volumn 12, Issue 6, 2012, Pages 667-671

Recent and future antiepileptic drugs and their impact on cognition: What can we expect?

Author keywords

antiepileptic drugs; brivaracetam; epilepsy; eslicarbazepine; ganaxolone; lacosamide; perampanel; retigabine; rufinamide

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; ANTICONVULSIVE AGENT; BRIVARACETAM; ESLICARBAZEPINE ACETATE; ETIRACETAM; GANAXOLONE; HARKOSERIDE; LORAZEPAM; OXCARBAZEPINE; PERAMPANEL; PHENYTOIN; PREGABALIN; RETIGABINE; RUFINAMIDE; VALPROIC ACID;

EID: 84861753399     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/ern.12.51     Document Type: Review
Times cited : (22)

References (39)
  • 3
    • 59149102224 scopus 로고    scopus 로고
    • Antiepileptic drug-Induced cognitive adverse effects: Potential mechanisms and contributing factors
    • Mula M, Trimble MR. Antiepileptic drug-induced cognitive adverse effects: potential mechanisms and contributing factors. CNS Drugs 23(2), 121-137 (2009
    • (2009) CNS Drugs , vol.23 , Issue.2 , pp. 121-137
    • Mula, M.1    Trimble, M.R.2
  • 4
    • 36849006900 scopus 로고    scopus 로고
    • Neuropsychological and behavioral effects of antiepilepsy drugs
    • DOI 10.1007/s11065-007-9043-9, Special Issue Neuropsychology of Epilepsy: Current Trends
    • Loring DW, Marino S, Meador KJ. Neuropsychological and behavioral effects of antiepilepsy drugs. Neuropsychol. Rev. 17(4), 413-425 (2007 (Pubitemid 350231552)
    • (2007) Neuropsychology Review , vol.17 , Issue.4 , pp. 413-425
    • Loring, D.W.1    Marino, S.2    Meador, K.J.3
  • 5
    • 72949114263 scopus 로고    scopus 로고
    • Cognition across the lifespan: Antiepileptic drugs, epilepsy, or both
    • Hermann B, Meador KJ, Gaillard WD, Cramer JA. Cognition across the lifespan: antiepileptic drugs, epilepsy, or both? Epilepsy Behav. 17(1), 1-5 (2010
    • (2010) Epilepsy Behav. , vol.17 , Issue.1 , pp. 1-5
    • Hermann, B.1    Meador, K.J.2    Gaillard, W.D.3    Cramer, J.A.4
  • 6
    • 0026775168 scopus 로고
    • Cognitive function - Victim of disease or hostage to treatment
    • Dreifuss FE. Cognitive function - victim of disease or hostage to treatment? Epilepsia 33(Suppl. 1), S7-12 (1992
    • (1992) Epilepsia , vol.33 , Issue.SUPPL. 1
    • Dreifuss, F.E.1
  • 8
    • 33846234734 scopus 로고    scopus 로고
    • Lacosamide
    • DOI 10.1016/j.nurt.2006.10.002, PII S1933721306001759, New Antiepileptic Drugs: Discovery, Development, and Update
    • Doty P, Rudd GD, Stoehr T, Thomas D. Lacosamide. Neurotherapeutics 4(1), 145-148 (2007 (Pubitemid 46107317)
    • (2007) Neurotherapeutics , vol.4 , Issue.1 , pp. 145-148
    • Doty, P.1    Rudd, G.D.2    Stoehr, T.3    Thomas, D.4
  • 9
    • 61849088333 scopus 로고    scopus 로고
    • SP755 study group adjunctive lacosamide for partial-Onset seizures: Efficacy and safety results from a randomized controlled trial
    • Halász P, Kälviäinen R, Mazurkiewicz- Beldzinska M et al.; SP755 Study Group. Adjunctive lacosamide for partial-onset seizures: efficacy and safety results from a randomized controlled trial. Epilepsia 50(3), 443-453 (2009
    • (2009) Epilepsia , vol.50 , Issue.3 , pp. 443-453
    • Halász, P.1    Kälviäinen, R.2    Mazurkiewicz-Beldzinska, M.3
  • 10
    • 40849086321 scopus 로고    scopus 로고
    • Lacosamide: An investigational drug for adjunctive treatment of partial-onset seizures
    • DOI 10.1358/dot.2008.44.1.1178468
    • Ben-Menachem E. Lacosamide: an investigational drug for adjunctive treatment of partial-onset seizures. Drugs Today 44(1), 35-40 (2008 (Pubitemid 351397411)
    • (2008) Drugs of Today , vol.44 , Issue.1 , pp. 35-40
    • Ben-Menachem, E.1
  • 11
    • 77953033494 scopus 로고    scopus 로고
    • Lacosamide as adjunctive therapy for partial-onset seizures: A randomized controlled trial
    • SP754 Study Group
    • Chung S, Sperling MR, Biton V et al.; SP754 Study Group. Lacosamide as adjunctive therapy for partial-onset seizures: a randomized controlled trial. Epilepsia 51(6), 958-967 (2010
    • (2010) Epilepsia , vol.51 , Issue.6 , pp. 958-967
    • Chung, S.1    Sperling, M.R.2    Biton, V.3
  • 12
    • 72049099610 scopus 로고    scopus 로고
    • Comparative study of five antiepileptic drugs on a translational cognitive measure in the rat: Relationship to antiepileptic property
    • Higgins GA, Breysse N, Undzys E et al. Comparative study of five antiepileptic drugs on a translational cognitive measure in the rat: relationship to antiepileptic property. Psychopharmacology (Berl.) 207(4), 513-527 (2010
    • (2010) Psychopharmacology (Berl.) , vol.207 , Issue.4 , pp. 513-527
    • Higgins, G.A.1    Breysse, N.2    Undzys, E.3
  • 13
    • 34548358604 scopus 로고    scopus 로고
    • Rufinamide
    • DOI 10.1358/dot.2007.43.7.1067344
    • Heaney D, Walker MC. Rufinamide. Drugs Today 43(7), 455-460 (2007 (Pubitemid 47344922)
    • (2007) Drugs of Today , vol.43 , Issue.7 , pp. 455-460
    • Heaney, D.1    Walker, M.C.2
  • 14
    • 44949184519 scopus 로고    scopus 로고
    • Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome
    • Glauser T, Kluger G, Sachdeo R, Krauss G, Perdomo C, Arroyo S. Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome. Neurology 70(21), 1950-1958 (2008
    • (2008) Neurology , vol.70 , Issue.21 , pp. 1950-1958
    • Glauser, T.1    Kluger, G.2    Sachdeo, R.3    Krauss, G.4    Perdomo, C.5    Arroyo, S.6
  • 15
    • 80052566407 scopus 로고    scopus 로고
    • Rufinamide from clinical trials to clinical practice in the United States and Europe
    • Resnick T, Arzimanoglou A, Brown LW et al. Rufinamide from clinical trials to clinical practice in the United States and Europe. Epileptic Disord. 13(Suppl. 1), S27-S43 (2011
    • (2011) Epileptic Disord. , vol.13 , Issue.SUPPL. 1
    • Resnick, T.1    Arzimanoglou, A.2    Brown, L.W.3
  • 16
    • 33746111455 scopus 로고    scopus 로고
    • The effect of the new antiepileptic drug rufinamide on cognitive functions
    • DOI 10.1111/j.1528-1167.2006.00589.x
    • Aldenkamp AP, Alpherts WC. The effect of the new antiepileptic drug rufinamide on cognitive functions. Epilepsia 47(7), 1153-1159 (2006 (Pubitemid 44086750)
    • (2006) Epilepsia , vol.47 , Issue.7 , pp. 1153-1159
    • Aldenkamp, A.P.1    Alpherts, W.C.J.2
  • 17
    • 79955592696 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy
    • RESTORE 1/Study 301 Investigators
    • French JA, Abou-Khalil BW, Leroy RF et al.; RESTORE 1/Study 301 Investigators. Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy. Neurology 76(18), 1555-1563 (2011
    • (2011) Neurology , vol.76 , Issue.18 , pp. 1555-1563
    • French, J.A.1    Abou-Khalil, B.W.2    Leroy, R.F.3
  • 18
    • 78649984382 scopus 로고    scopus 로고
    • Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy
    • RESTORE 2 Study Group
    • Brodie MJ, Lerche H, Gil-Nagel A et al.; RESTORE 2 Study Group. Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy. Neurology 75(20), 1817-1824 (2010
    • (2010) Neurology , vol.75 , Issue.20 , pp. 1817-1824
    • Brodie, M.J.1    Lerche, H.2    Gil-Nagel, A.3
  • 19
    • 34247252905 scopus 로고    scopus 로고
    • Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures
    • DOI 10.1212/01.wnl.0000259034.45049.00, PII 0000611420070410000009
    • Porter RJ, Partiot A, Sachdeo R, Nohria V, Alves WM; 205 Study Group. Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures. Neurology 68(15), 1197-1204 (2007 (Pubitemid 46608467)
    • (2007) Neurology , vol.68 , Issue.15 , pp. 1197-1204
    • Porter, R.J.1    Partiot, A.2    Sachdeo, R.3    Nohria, V.4    Alves, W.M.5
  • 20
    • 70649099046 scopus 로고    scopus 로고
    • Antimanic efficacy of retigabine in a proposed mouse model of bipolar disorder
    • Dencker D, Husum H. Antimanic efficacy of retigabine in a proposed mouse model of bipolar disorder. Behav. Brain Res. 207(1), 78-83 (2010
    • (2010) Behav. Brain Res. , vol.207 , Issue.1 , pp. 78-83
    • Dencker, D.1    Husum, H.2
  • 21
    • 37049038680 scopus 로고    scopus 로고
    • Effect of the new antiepileptic drug retigabine in a rodent model of mania
    • DOI 10.1016/j.yebeh.2007.09.023, PII S1525505007003290
    • Dencker D, Dias R, Pedersen ML, Husum H. Effect of the new antiepileptic drug retigabine in a rodent model of mania. Epilepsy Behav. 12(1), 49-53 (2008 (Pubitemid 350246381)
    • (2008) Epilepsy and Behavior , vol.12 , Issue.1 , pp. 49-53
    • Dencker, D.1    Dias, R.2    Pedersen, M.L.3    Husum, H.4
  • 23
    • 33745251005 scopus 로고    scopus 로고
    • New antiepileptic drugs that are second generation to existing antiepileptic drugs
    • Bialer M. New antiepileptic drugs that are second generation to existing antiepileptic drugs. Expert Opin. Investig. Drugs 15(6), 637-647 (2006
    • (2006) Expert Opin. Investig. Drugs , vol.15 , Issue.6 , pp. 637-647
    • Bialer, M.1
  • 24
    • 57849141134 scopus 로고    scopus 로고
    • Progress report on new antiepileptic drugs: A summary of the ninth eilat conference eilat ix
    • Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS. Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 83(1), 1-43 (2009
    • (2009) Epilepsy Res. , vol.83 , Issue.1 , pp. 1-43
    • Bialer, M.1    Johannessen, S.I.2    Levy, R.H.3    Perucca, E.4    Tomson, T.5    White, H.S.6
  • 26
    • 33847611166 scopus 로고    scopus 로고
    • Eslicarbazepine acetate: A double-blind, add-on, placebo-controlled exploratory trial in adult patients with partial-onset seizures
    • DOI 10.1111/j.1528-1167.2007.00984.x
    • Elger C, Bialer M, Cramer JA, Maia J, Almeida L, Soares-da-Silva P. Eslicarbazepine acetate: a double-blind, add-on, placebo-controlled exploratory trial in adult patients with partial-onset seizures. Epilepsia 48(3), 497-504 (2007 (Pubitemid 46365199)
    • (2007) Epilepsia , vol.48 , Issue.3 , pp. 497-504
    • Elger, C.1    Bialer, M.2    Cramer, J.A.3    Maia, J.4    Almeida, L.5    Soares-Da-Silva, P.6
  • 27
    • 61849168486 scopus 로고    scopus 로고
    • Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: A randomized, double-blind, placebo-controlled, parallel-group Phase III study
    • BIA-2093-301 Investigators Study Group
    • Elger C, Halász P, Maia J, Almeida L, Soares-da-Silva P; BIA-2093-301 Investigators Study Group. Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: a randomized, double-blind, placebo-controlled, parallel-group Phase III study. Epilepsia 50(3), 454-463 (2009
    • (2009) Epilepsia , vol.50 , Issue.3 , pp. 454-463
    • Elger, C.1    Halász, P.2    Maia, J.3    Almeida, L.4    Soares-da-Silva, P.5
  • 28
    • 70349972675 scopus 로고    scopus 로고
    • Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures
    • BIA-2093-303 Investigators Study Group
    • Gil-Nagel A, Lopes-Lima J, Almeida L, Maia J, Soares-da-Silva P; BIA-2093-303 Investigators Study Group. Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures. Acta Neurol. Scand. 120(5), 281-287 (2009
    • (2009) Acta Neurol. Scand. , vol.120 , Issue.5 , pp. 281-287
    • Gil-Nagel, A.1    Lopes-Lima, J.2    Almeida, L.3    Maia, J.4    Soares-da-Silva, P.5
  • 29
    • 78649248897 scopus 로고    scopus 로고
    • Long-term efficacy and safety of eslicarbazepine acetate: Results of a 1-year open-label extension study in partial-onset seizures in adults with epilepsy
    • BIA-2093-301 Study Group
    • Halász P, Cramer JA, Hodoba D et al.; BIA-2093-301 Study Group. Long-term efficacy and safety of eslicarbazepine acetate: results of a 1-year open-label extension study in partial-onset seizures in adults with epilepsy. Epilepsia 51(10), 1963-1969 (2010
    • (2010) Epilepsia , vol.51 , Issue.10 , pp. 1963-1969
    • Halász, P.1    Cramer, J.A.2    Hodoba, D.3
  • 31
    • 77955578218 scopus 로고    scopus 로고
    • Effect of eslicarbazepine acetate and oxcarbazepine on cognition and psychomotor function in healthy volunteers
    • MiloVan D, Almeida L, Romach MK et al. Effect of eslicarbazepine acetate and oxcarbazepine on cognition and psychomotor function in healthy volunteers. Epilepsy Behav. 18(4), 366-373 (2010
    • (2010) Epilepsy Behav. , vol.18 , Issue.4 , pp. 366-373
    • MiloVan, D.1    Almeida, L.2    Romach, M.K.3
  • 32
    • 78650178478 scopus 로고    scopus 로고
    • Progress report on new antiepileptic drugs: A summary of the Tenth Eilat Conference (EILAT X)
    • Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS. Progress report on new antiepileptic drugs: a summary of the Tenth Eilat Conference (EILAT X). Epilepsy Res. 92(2-3), 89-124 (2010
    • (2010) Epilepsy Res. , vol.92 , Issue.2-3 , pp. 89-124
    • Bialer, M.1    Johannessen, S.I.2    Levy, R.H.3    Perucca, E.4    Tomson, T.5    White, H.S.6
  • 33
    • 77955452826 scopus 로고    scopus 로고
    • Adjunctive brivaracetam for refractory partial-Onset seizures: A randomized, controlled trial
    • N01193 Study Group
    • French JA, Costantini C, Brodsky A, von Rosenstiel P; N01193 Study Group. Adjunctive brivaracetam for refractory partial-onset seizures: a randomized, controlled trial. Neurology 75(6), 519-525 (2010
    • (2010) Neurology , vol.75 , Issue.6 , pp. 519-525
    • French, J.A.1    Costantini, C.2    Brodsky, A.3    Von Rosenstiel P4    5
  • 34
    • 79951652267 scopus 로고    scopus 로고
    • Neurocognitive effects of brivaracetam, levetiracetam, and lorazepam
    • Meador KJ, Gevins A, Leese PT, Otoul C, Loring DW. Neurocognitive effects of brivaracetam, levetiracetam, and lorazepam. Epilepsia 52(2), 264-272 (2011
    • (2011) Epilepsia , vol.52 , Issue.2 , pp. 264-272
    • Meador, K.J.1    Gevins, A.2    Leese, P.T.3    Otoul, C.4    Loring, D.W.5
  • 35
    • 84155186559 scopus 로고    scopus 로고
    • Tolerability and safety of perampanel: Two randomized dose-escalation studies
    • Krauss GL, Bar M, Biton V et al. Tolerability and safety of perampanel: two randomized dose-escalation studies. Acta Neurol. Scand. 125(1), 8-15 (2012
    • (2012) Acta Neurol. Scand. , vol.125 , Issue.1 , pp. 8-15
    • Krauss, G.L.1    Bar, M.2    Biton, V.3
  • 36
    • 17044396861 scopus 로고    scopus 로고
    • AMPA receptor stimulation mediates the antidepressant-Like effect of a group II metabotropic glutamate receptor antagonist
    • Karasawa J, Shimazaki T, Kawashima N, Chaki S. AMPA receptor stimulation mediates the antidepressant-like effect of a group II metabotropic glutamate receptor antagonist. Brain Res. 1042(1), 92-98 (2005
    • (2005) Brain Res. , vol.1042 , Issue.1 , pp. 92-98
    • Karasawa, J.1    Shimazaki, T.2    Kawashima, N.3    Chaki, S.4
  • 37
    • 35348856414 scopus 로고    scopus 로고
    • Blockade of the metabotropic glutamate 2/3 receptors enhances social memory via the AMPA receptor in rats
    • DOI 10.1016/j.ejphar.2007.08.006, PII S0014299907008965
    • Shimazaki T, Kaku A, Chaki S. Blockade of the metabotropic glutamate 2/3 receptors enhances social memory via the AMPA receptor in rats. Eur. J. Pharmacol. 575(1-3), 94-97 (2007 (Pubitemid 47576076)
    • (2007) European Journal of Pharmacology , vol.575 , Issue.1-3 , pp. 94-97
    • Shimazaki, T.1    Kaku, A.2    Chaki, S.3
  • 38
    • 0022483382 scopus 로고
    • Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor
    • Majewska MD, Harrison NL, Schwartz RD, Barker JL, Paul SM. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. Science 232(4753), 1004-1007 (1986 (Pubitemid 16085410)
    • (1986) Science , vol.232 , Issue.4753 , pp. 1004-1007
    • Majewska, M.D.1    Harrison, N.L.2    Schwartz, R.D.3
  • 39
    • 34250359480 scopus 로고    scopus 로고
    • Inhibition of evoked glutamate release by neurosteroid allopregnanolone via inhibition of l-type calcium channels in rat medial prefrontal cortex
    • Hu AQ, Wang ZM, Lan DM et al. Inhibition of evoked glutamate release by neurosteroid allopregnanolone via inhibition of l-type calcium channels in rat medial prefrontal cortex. Neuropsychopharmacology 32(7), 1477-1489 (2007)
    • (2007) Neuropsychopharmacology , vol.32 , Issue.7 , pp. 1477-1489
    • Hu, A.Q.1    Wang, Z.M.2    Lan, D.M.3


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