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Volumn 4, Issue 1, 2007, Pages 145-148

Lacosamide

Author keywords

anticonvulsants; antiepileptic drugs; epilepsy; Lacosamide; partial onset seizures

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; COLLAPSIN RESPONSE MEDIATOR PROTEIN; COLLAPSIN RESPONSE MEDIATOR PROTEIN 2; DIGOXIN; DRUG METABOLITE; ETHINYLESTRADIOL; ETIRACETAM; HARKOSERIDE; LAMOTRIGINE; LEVONORGESTREL; METFORMIN; O NORLACOSAMIDE; OMEPRAZOLE; ORAL CONTRACEPTIVE AGENT; PHENOBARBITAL; PHENYTOIN; PLACEBO; TOPIRAMATE; UNCLASSIFIED DRUG; VALPROIC ACID;

EID: 33846234734     PISSN: 19337213     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nurt.2006.10.002     Document Type: Article
Times cited : (167)

References (28)
  • 1
    • 0033492029 scopus 로고    scopus 로고
    • The anticonvulsant activities of N-benzyl 3-methoxypropionamides
    • Andurkar S.V., Stables J.P., and Kohn H. The anticonvulsant activities of N-benzyl 3-methoxypropionamides. Bioorg Med Chem 7 (1999) 2381-2389
    • (1999) Bioorg Med Chem , vol.7 , pp. 2381-2389
    • Andurkar, S.V.1    Stables, J.P.2    Kohn, H.3
  • 2
    • 27644510366 scopus 로고    scopus 로고
    • The novel antiepileptic drug lacosamide blocks behavioral and brain metabolic manifestations of seizure activity in the 6 Hz psychomotor seizure model
    • Duncan G.E., and Kohn H. The novel antiepileptic drug lacosamide blocks behavioral and brain metabolic manifestations of seizure activity in the 6 Hz psychomotor seizure model. Epilepsy Res 67 (2005) 81-87
    • (2005) Epilepsy Res , vol.67 , pp. 81-87
    • Duncan, G.E.1    Kohn, H.2
  • 3
    • 0037869179 scopus 로고    scopus 로고
    • SPM-927 (Schwarz Pharma)
    • Hovinga C.A. SPM-927 (Schwarz Pharma). IDrugs 6 (2003) 479-485
    • (2003) IDrugs , vol.6 , pp. 479-485
    • Hovinga, C.A.1
  • 4
    • 33846248644 scopus 로고    scopus 로고
    • The pre-clinical profile of the novel anticonvulsant lacosamide
    • Abstract
    • Stohr T., Stables J.P., Wilcox K., and White H.S. The pre-clinical profile of the novel anticonvulsant lacosamide. Epilepsia 46 suppl 6 (2005) 373 Abstract
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 6 , pp. 373
    • Stohr, T.1    Stables, J.P.2    Wilcox, K.3    White, H.S.4
  • 5
    • 0034841551 scopus 로고    scopus 로고
    • Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues
    • LeTiran A., Stables J.P., and Kohn H. Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues. Bioorg Med Chem 9 (2001) 2693-2708
    • (2001) Bioorg Med Chem , vol.9 , pp. 2693-2708
    • LeTiran, A.1    Stables, J.P.2    Kohn, H.3
  • 6
    • 33750904279 scopus 로고    scopus 로고
    • Effects of the novel antiepileptic drug lacosamide on the development of amygdala kindling in rats
    • Brandt C., Heile A., Potschka H., Stoehr T., and Löscher W. Effects of the novel antiepileptic drug lacosamide on the development of amygdala kindling in rats. Epilepsia 47 (2006) 1803-1809
    • (2006) Epilepsia , vol.47 , pp. 1803-1809
    • Brandt, C.1    Heile, A.2    Potschka, H.3    Stoehr, T.4    Löscher, W.5
  • 7
  • 8
    • 33646911126 scopus 로고    scopus 로고
    • Seeking a mechanism of action for the novel anticonvulsant lacosamide
    • Errington A.C., Coyne L., Stohr T., Selve N., and Lees G. Seeking a mechanism of action for the novel anticonvulsant lacosamide. Neuropharmacology 50 (2006) 1016-1029
    • (2006) Neuropharmacology , vol.50 , pp. 1016-1029
    • Errington, A.C.1    Coyne, L.2    Stohr, T.3    Selve, N.4    Lees, G.5
  • 9
    • 3042798891 scopus 로고    scopus 로고
    • The neurobiology of antiepileptic drugs
    • Rogawski M.A., and Loscher W. The neurobiology of antiepileptic drugs. Nat Rev Neurosci 5 (2004) 553-564
    • (2004) Nat Rev Neurosci , vol.5 , pp. 553-564
    • Rogawski, M.A.1    Loscher, W.2
  • 10
    • 33846202426 scopus 로고    scopus 로고
    • Stoehr T, Lees G, Errington A, et al. Lacosamide has a dual mode of action: selective enhancement of sodium channel slow inactivation and modulation of CRMP-2. Presented at the 9th International Conference on the Mechanisms and Treatment of Neuropathic Pain; November 4, 2005; Bermuda.
  • 11
    • 11144259374 scopus 로고    scopus 로고
    • Reduction of hippocampal collapsin response mediated protein-2 in patients with mesial temporal lobe epilepsy
    • Czech T., Yang J.W., Csaszar E., Kappler J., Baumgartner C., and Lubec G. Reduction of hippocampal collapsin response mediated protein-2 in patients with mesial temporal lobe epilepsy. Neurochem Res 29 (2004) 2189-2196
    • (2004) Neurochem Res , vol.29 , pp. 2189-2196
    • Czech, T.1    Yang, J.W.2    Csaszar, E.3    Kappler, J.4    Baumgartner, C.5    Lubec, G.6
  • 13
    • 33846242456 scopus 로고    scopus 로고
    • Food does not affect the pharmacokinetics of SPM 927
    • Abstract
    • Cawello W., Kropeit D., Schiltmeyer B., Hammes W., and Horstmann R. Food does not affect the pharmacokinetics of SPM 927. Epilepsia 45 suppl 7 (2004) 307 Abstract
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 7 , pp. 307
    • Cawello, W.1    Kropeit, D.2    Schiltmeyer, B.3    Hammes, W.4    Horstmann, R.5
  • 14
    • 33846193132 scopus 로고    scopus 로고
    • Bioequivalence of short-time infusions compared to oral administration of SPM 927
    • Abstract
    • Kropeit D., Schiltmeyer B., Cawello W., Hammes W., and Horstmann R. Bioequivalence of short-time infusions compared to oral administration of SPM 927. Epilepsia 45 suppl 7 (2004) 123-124 Abstract
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 7 , pp. 123-124
    • Kropeit, D.1    Schiltmeyer, B.2    Cawello, W.3    Hammes, W.4    Horstmann, R.5
  • 15
    • 0036752811 scopus 로고    scopus 로고
    • Progress report on new antiepileptic drugs: a summary of the Sixth Eilat Conference (EILAT VI)
    • Bialer M., Johannessen S.I., Kupferberg H.J., Levy R.H., Loiseau P., and Perucca E. Progress report on new antiepileptic drugs: a summary of the Sixth Eilat Conference (EILAT VI). Epilepsy Res 51 (2002) 31-71
    • (2002) Epilepsy Res , vol.51 , pp. 31-71
    • Bialer, M.1    Johannessen, S.I.2    Kupferberg, H.J.3    Levy, R.H.4    Loiseau, P.5    Perucca, E.6
  • 16
    • 4644301804 scopus 로고    scopus 로고
    • Progress report on new antiepileptic drugs: a summary of the Seventh Eilat Conference (EILAT VII)
    • Bialer M., Johannessen S.I., Kupferberg H.J., Levy R.H., Perucca E., and Tomson T. Progress report on new antiepileptic drugs: a summary of the Seventh Eilat Conference (EILAT VII). Epilepsy Res 61 (2004) 1-48
    • (2004) Epilepsy Res , vol.61 , pp. 1-48
    • Bialer, M.1    Johannessen, S.I.2    Kupferberg, H.J.3    Levy, R.H.4    Perucca, E.5    Tomson, T.6
  • 17
    • 11144232600 scopus 로고    scopus 로고
    • Basic clinical pharmacological investigations of the new antiepileptic drug SPM 927
    • Abstract
    • Horstmann R., Bonn R., Cawello W., Doty P., and Rudd D. Basic clinical pharmacological investigations of the new antiepileptic drug SPM 927. Epilepsia 43 suppl 7 (2002) 188 Abstract
    • (2002) Epilepsia , vol.43 , Issue.SUPPL. 7 , pp. 188
    • Horstmann, R.1    Bonn, R.2    Cawello, W.3    Doty, P.4    Rudd, D.5
  • 18
    • 33846244930 scopus 로고    scopus 로고
    • Pharmacokinetics of the new antiepileptic drug SPM 927 in human subjects with different age and gender
    • Abstract
    • Schiltmeyer B., Cawello W., Kropeit D., Hammes W., and Horstmann R. Pharmacokinetics of the new antiepileptic drug SPM 927 in human subjects with different age and gender. Epilepsia 45 suppl 7 (2004) 313 Abstract
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 7 , pp. 313
    • Schiltmeyer, B.1    Cawello, W.2    Kropeit, D.3    Hammes, W.4    Horstmann, R.5
  • 20
    • 11144238504 scopus 로고    scopus 로고
    • SPM 927 does not interact with valproic acid and carbamazepine
    • Abstract
    • Horstmann R., Bonn R., Cawello W., Doty P., and Rudd D. SPM 927 does not interact with valproic acid and carbamazepine. Epilepsia 44 suppl 9 (2003) 97 Abstract
    • (2003) Epilepsia , vol.44 , Issue.SUPPL. 9 , pp. 97
    • Horstmann, R.1    Bonn, R.2    Cawello, W.3    Doty, P.4    Rudd, D.5
  • 21
    • 33846225086 scopus 로고    scopus 로고
    • Kropeit D, Scharfenecker U, Schiltmeyer B, et al. Lacosamide has low potential for drug-drug interaction. Presented at the 59th Annual Meeting of the American Epilepsy Society; December 2, 2005; Washington, DC.
  • 22
    • 33846258011 scopus 로고    scopus 로고
    • Evaluation of the effect of oral lacosamide on concomitant AED plasma concentrations in patients with partial seizures
    • Abstract
    • Jatuzis D., Biton V., Ben-Menachem E., Abou-Khalil B., Doty P., and Rudd G.D. Evaluation of the effect of oral lacosamide on concomitant AED plasma concentrations in patients with partial seizures. Epilepsia 46 suppl 8 (2005) 170 Abstract
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 8 , pp. 170
    • Jatuzis, D.1    Biton, V.2    Ben-Menachem, E.3    Abou-Khalil, B.4    Doty, P.5    Rudd, G.D.6
  • 23
    • 0000248471 scopus 로고    scopus 로고
    • Harkoseride: safety and tolerability of a new antiepileptic drug in patients with refractory partial seizures
    • Abstract
    • Fountain N.B., French J.A., and Privitera M.D. Harkoseride: safety and tolerability of a new antiepileptic drug in patients with refractory partial seizures. Epilepsia 41 suppl 7 (2000) 169 Abstract
    • (2000) Epilepsia , vol.41 , Issue.SUPPL. 7 , pp. 169
    • Fountain, N.B.1    French, J.A.2    Privitera, M.D.3
  • 24
    • 1942471551 scopus 로고    scopus 로고
    • An open-label, maximum tolerated dose trial to evaluate oral SPM 927 as adjunctive therapy in patients with partial seizures
    • Abstract
    • Sachdeo R., Montouris G., Beydoun A., et al. An open-label, maximum tolerated dose trial to evaluate oral SPM 927 as adjunctive therapy in patients with partial seizures. Neurology 60 suppl 1 (2003) A433 Abstract
    • (2003) Neurology , vol.60 , Issue.SUPPL. 1
    • Sachdeo, R.1    Montouris, G.2    Beydoun, A.3
  • 25
    • 25844499529 scopus 로고    scopus 로고
    • Efficacy and safety of adjunctive oral lacosamide for the treatment of partial-onset seizures in patients with epilepsy
    • Abstract
    • Ben-Menachem E., Biton V., Jatuzis D., et al. Efficacy and safety of adjunctive oral lacosamide for the treatment of partial-onset seizures in patients with epilepsy. Neurology 64 suppl 1 (2005) A187 Abstract
    • (2005) Neurology , vol.64 , Issue.SUPPL. 1
    • Ben-Menachem, E.1    Biton, V.2    Jatuzis, D.3
  • 26
    • 33846220582 scopus 로고    scopus 로고
    • Lacosamide: efficacy and safety as oral adjunctive therapy in adults with partial seizures
    • Abstract
    • Halasz P., Kalviainen R., Mazurkiewicz-Beldzinska M., Rosenow F., Doty P., and Sullivan T. Lacosamide: efficacy and safety as oral adjunctive therapy in adults with partial seizures. Epilepsia 47 suppl 4 (2006) 3 Abstract
    • (2006) Epilepsia , vol.47 , Issue.SUPPL. 4 , pp. 3
    • Halasz, P.1    Kalviainen, R.2    Mazurkiewicz-Beldzinska, M.3    Rosenow, F.4    Doty, P.5    Sullivan, T.6
  • 27
    • 25844489785 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics of intravenous lacosamide as replacement for oral lacosamide in subjects with partial seizures
    • Abstract
    • Biton V., Rosenfeld W., Fountain N.B., Vaiciene N., Whitesides J., and Sommerville K. Safety, tolerability, and pharmacokinetics of intravenous lacosamide as replacement for oral lacosamide in subjects with partial seizures. Neurology 64 suppl 1 (2005) A119 Abstract
    • (2005) Neurology , vol.64 , Issue.SUPPL. 1
    • Biton, V.1    Rosenfeld, W.2    Fountain, N.B.3    Vaiciene, N.4    Whitesides, J.5    Sommerville, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.