A silk hydrogel-based delivery system of bone morphogenetic protein for the treatment of large bone defects

Journal of the Mechanical Behavior of Biomedical Materials

Volumn 11, Issue , 2012, Pages 123-131

  Diab, Tamim ^a   Pritchard, Eleanor M ^b   Uhrig, Brent A ^a,c   Boerckel, Joel D ^a,c   Kaplan, David L ^b   Guldberg, Robert E ^a,c  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b Tufts University   (United States)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Biomaterials; Bone regeneration; Growth factor carrier; Silk

Indexed keywords

BIOMATERIAL SCAFFOLDS; BIOMECHANICAL PROPERTIES; BIOMECHANICAL TESTING; BONE DEFECT; BONE FORMATION; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; BONE REPAIR; DEFECT MODEL; DELIVERY SYSTEMS; DISEASE TRANSMISSION; ELECTROSPUNS; GROWTH FACTOR; HISTOLOGICAL EVALUATION; NANOFIBER MESH; PCL NANOFIBERS; RECOMBINANT BONE MORPHOGENETIC PROTEIN-2; RESEARCH EFFORTS; SILK FIBROIN; SPRAGUE-DAWLEY RATS;

BIOMATERIALS; BIOMECHANICS; BONE; DEFECTS; POLYCAPROLACTONE; SILK; SURGERY; TISSUE; TUBES (COMPONENTS);

HYDROGELS;

BIOMATERIAL; NANOFIBER; POLYCAPROLACTONE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEFECT; BONE REGENERATION; COMPUTED TOMOGRAPHY SCANNER; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FEMUR; HISTOLOGY; HYDROGEL; IMAGING SYSTEM; MALE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT; SILK; TREATMENT OUTCOME; X RAY;

ANIMALS; BONE DISEASES; BONE MORPHOGENETIC PROTEIN 2; DRUG CARRIERS; FEMUR; FIBROINS; HYDROGELS; NANOFIBERS; POLYESTERS; RATS; X-RAY MICROTOMOGRAPHY;

EID: 84861700017     PISSN: 17516161     EISSN: 18780180     Source Type: Journal    
DOI: 10.1016/j.jmbbm.2011.11.007     Document Type: Article

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