Biophysical characterization of M1476I, a sodium channel founder mutation associated with cold-induced myotonia in French Canadians

Journal of Physiology

Volumn 590, Issue 11, 2012, Pages 2629-2644

  Zhao, Juan ^a   Duprè, Nicolas ^b   Puymirat, Jack ^b   Chahine, Mohamed ^a  

^a CENTRE DE RECHERCHE DE L INSTITUT UNIVERSITAIRE EN SANTÉ MENTALE DE QUÉBEC   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MEXILETINE; POTASSIUM; SODIUM CHANNEL NAV1.4;

ARTICLE; BIOPHYSICS; COLD INDUCED MYOTONIA; COLD SENSITIVITY; CONTROLLED STUDY; DRUG EFFICACY; DRUG SENSITIVITY; DRUG TARGETING; ETHNIC GROUP; FOUNDER EFFECT; FRENCH CANADIAN; GENE MUTATION; HEART DEPOLARIZATION; HETEROZYGOTE; HUMAN; HUMAN CELL; MYOTONIA; PATCH CLAMP; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; SODIUM CURRENT; STEADY STATE; TEMPERATURE SENSITIVITY;

CANADA; CELL LINE; COLD TEMPERATURE; HUMANS; MEXILETINE; MUTATION; MYOTONIA; POTASSIUM; SODIUM CHANNELS; VOLTAGE-GATED SODIUM CHANNEL BLOCKERS;

EID: 84861688069     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2011.223461     Document Type: Article

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