Sodium channelopathies of skeletal muscle result from gain or loss of function

Pflugers Archiv European Journal of Physiology

Volumn 460, Issue 2, 2010, Pages 239-248

  Jurkat Rott, Karin ^a   Holzherr, Boris ^a   Fauler, Michael ^a   Lehmann Horn, Frank ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Channels; Congenital myasthenic syndrome; Excitability; Hyperkalemic periodic paralysis; Hypokalemic periodic paralysis; Muscle; Muscle strength; Myotonia; Paramyotonia congenita; Sodium channel

Indexed keywords

ACETAZOLAMIDE; ALDOSTERONE ANTAGONIST; CALCIUM CHANNEL L TYPE; CARBONATE DEHYDRATASE INHIBITOR; FLECAINIDE; HYDROCHLOROTHIAZIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; LIDOCAINE; MEXILETINE; NICOTINIC RECEPTOR; POTASSIUM; POTASSIUM SPARING DIURETIC AGENT; SODIUM CHANNEL; SODIUM CHANNEL NAV1.4;

CHANNEL GATING; CONGENITAL MYASTHENIC SYNDROME; GENE MUTATION; HUMAN; HYPOKALEMIC PERIODIC PARALYSIS; MUSCLE ACTION POTENTIAL; MUSCLE FIBER MEMBRANE POTENTIAL; MUSCLE FIBER MEMBRANE STEADY POTENTIAL; MUSCLE STIFFNESS; MUSCLE WEAKNESS; MYOTONIA; NONHUMAN; PATHOGENESIS; PERIODIC PARALYSIS; PRIORITY JOURNAL; REVIEW; SKELETAL MUSCLE; SODIUM CHANNELOPATHY; SODIUM CONDUCTANCE; SYMPTOM; THOMSEN DISEASE;

ACTION POTENTIALS; CHANNELOPATHIES; HUMANS; HYPOKALEMIC PERIODIC PARALYSIS; MEMBRANE POTENTIALS; MUSCLE PROTEINS; MUSCLE, SKELETAL; MYOTONIC DISORDERS; PARALYSIS, HYPERKALEMIC PERIODIC; POTASSIUM; SODIUM CHANNELS;

EID: 77955568196     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-010-0814-4     Document Type: Review

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