메뉴 건너뛰기




Volumn 318, Issue 11, 2012, Pages 1208-1212

Histone deacetylase (HDAC) inhibitors and regulation of TRAIL-induced apoptosis

Author keywords

Apoptosis; HDAC; TRAIL

Indexed keywords

APICIDIN; BENZAMIDE DERIVATIVE; BUTYRIC ACID; CYCLOPEPTIDE; DEATH RECEPTOR; DEPSIPEPTIDE; ENTINOSTAT; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; LAQ 842; OXAMFLATIN; REGULATOR PROTEIN; TRAPOXIN A; TRICHOSTATIN A; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; VALPROIC ACID; VORINOSTAT;

EID: 84861683009     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2012.02.005     Document Type: Review
Times cited : (40)

References (41)
  • 1
    • 58149296552 scopus 로고    scopus 로고
    • Tumor resistance to apoptosis
    • Fulda S. Tumor resistance to apoptosis. Int. J. Cancer 2009, 124:511-515.
    • (2009) Int. J. Cancer , vol.124 , pp. 511-515
    • Fulda, S.1
  • 3
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction?
    • Baylin S.B., Ohm J.E. Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction?. Nat. Rev. Cancer 2006, 6:107-116.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 4
    • 33644853802 scopus 로고    scopus 로고
    • Histone modifications: signalling receptors and potential elements of a heritable epigenetic code
    • Nightingale K.P., O'Neill L.P., Turner B.M. Histone modifications: signalling receptors and potential elements of a heritable epigenetic code. Curr. Opin. Genet. Dev. 2006, 16:125-136.
    • (2006) Curr. Opin. Genet. Dev. , vol.16 , pp. 125-136
    • Nightingale, K.P.1    O'Neill, L.P.2    Turner, B.M.3
  • 5
    • 21244467166 scopus 로고    scopus 로고
    • Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies
    • Bhalla K.N. Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies. J. Clin. Oncol. 2005, 23:3971-3993.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 3971-3993
    • Bhalla, K.N.1
  • 6
    • 0242610850 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA
    • Kim M.S., Blake M., Baek J.H., Kohlhagen G., Pommier Y., Carrier F. Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA. Cancer Res. 2003, 63:7291-7300.
    • (2003) Cancer Res. , vol.63 , pp. 7291-7300
    • Kim, M.S.1    Blake, M.2    Baek, J.H.3    Kohlhagen, G.4    Pommier, Y.5    Carrier, F.6
  • 7
    • 4644259264 scopus 로고    scopus 로고
    • Enhancement of xenograft tumor radiosensitivity by the histone deacetylase inhibitor MS-275 and correlation with histone hyperacetylation
    • Camphausen K., Scott T., Sproull M., Tofilon P.J. Enhancement of xenograft tumor radiosensitivity by the histone deacetylase inhibitor MS-275 and correlation with histone hyperacetylation. Clin. Cancer Res. 2004, 10:6066-6071.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 6066-6071
    • Camphausen, K.1    Scott, T.2    Sproull, M.3    Tofilon, P.J.4
  • 8
    • 40449140444 scopus 로고    scopus 로고
    • Modulation of TRAIL-induced apoptosis by HDAC inhibitors
    • Fulda S. Modulation of TRAIL-induced apoptosis by HDAC inhibitors. Curr. Cancer Drug Targets 2008, 8:132-140.
    • (2008) Curr. Cancer Drug Targets , vol.8 , pp. 132-140
    • Fulda, S.1
  • 9
    • 44749085513 scopus 로고    scopus 로고
    • Targeting the extrinsic apoptosis pathway in cancer
    • Ashkenazi A. Targeting the extrinsic apoptosis pathway in cancer. Cytokine Growth Factor Rev. 2008, 19:325-331.
    • (2008) Cytokine Growth Factor Rev. , vol.19 , pp. 325-331
    • Ashkenazi, A.1
  • 11
    • 12744261484 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies
    • Inoue S., MacFarlane M., Harper N., Wheat L.M., Dyer M.J., Cohen G.M. Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies. Cell Death Differ. 2004, 11(Suppl 2):S193-S206.
    • (2004) Cell Death Differ. , vol.11 , Issue.SUPPL. 2
    • Inoue, S.1    MacFarlane, M.2    Harper, N.3    Wheat, L.M.4    Dyer, M.J.5    Cohen, G.M.6
  • 12
    • 6444242600 scopus 로고    scopus 로고
    • Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells
    • Kim Y.H., Park J.W., Lee J.Y., Kwon T.K. Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells. Carcinogenesis 2004, 25:1813-1820.
    • (2004) Carcinogenesis , vol.25 , pp. 1813-1820
    • Kim, Y.H.1    Park, J.W.2    Lee, J.Y.3    Kwon, T.K.4
  • 13
    • 4344666663 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells
    • Nakata S., Yoshida T., Horinaka M., Shiraishi T., Wakada M., Sakai T. Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells. Oncogene 2004, 23:6261-6271.
    • (2004) Oncogene , vol.23 , pp. 6261-6271
    • Nakata, S.1    Yoshida, T.2    Horinaka, M.3    Shiraishi, T.4    Wakada, M.5    Sakai, T.6
  • 14
    • 11144358387 scopus 로고    scopus 로고
    • Cotreatment with histone deacetylase inhibitor LAQ824 enhances Apo-2L/tumor necrosis factor-related apoptosis inducing ligand-induced death inducing signaling complex activity and apoptosis of human acute leukemia cells
    • Guo F., Sigua C., Tao J., Bali P., George P., Li Y., Wittmann S., Moscinski L., Atadja P., Bhalla K. Cotreatment with histone deacetylase inhibitor LAQ824 enhances Apo-2L/tumor necrosis factor-related apoptosis inducing ligand-induced death inducing signaling complex activity and apoptosis of human acute leukemia cells. Cancer Res. 2004, 64:2580-2589.
    • (2004) Cancer Res. , vol.64 , pp. 2580-2589
    • Guo, F.1    Sigua, C.2    Tao, J.3    Bali, P.4    George, P.5    Li, Y.6    Wittmann, S.7    Moscinski, L.8    Atadja, P.9    Bhalla, K.10
  • 15
    • 22744437647 scopus 로고    scopus 로고
    • HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma
    • Singh T.R., Shankar S., Srivastava R.K. HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma. Oncogene 2005, 24:4609-4623.
    • (2005) Oncogene , vol.24 , pp. 4609-4623
    • Singh, T.R.1    Shankar, S.2    Srivastava, R.K.3
  • 16
    • 3242725832 scopus 로고    scopus 로고
    • Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1)
    • Chopin V., Slomianny C., Hondermarck H., Le Bourhis X. Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1). Exp. Cell. Res. 2004, 298:560-573.
    • (2004) Exp. Cell. Res. , vol.298 , pp. 560-573
    • Chopin, V.1    Slomianny, C.2    Hondermarck, H.3    Le Bourhis, X.4
  • 17
    • 27744597128 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors modulate renal cell carcinoma sensitivity to TRAIL/Apo-2L-induced apoptosis by enhancing TRAIL-R2 expression
    • VanOosten R.L., Moore J.M., Karacay B., Griffith T.S. Histone deacetylase inhibitors modulate renal cell carcinoma sensitivity to TRAIL/Apo-2L-induced apoptosis by enhancing TRAIL-R2 expression. Cancer Biol. Ther. 2005, 4:1104-1112.
    • (2005) Cancer Biol. Ther. , vol.4 , pp. 1104-1112
    • VanOosten, R.L.1    Moore, J.M.2    Karacay, B.3    Griffith, T.S.4
  • 18
    • 31544432335 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors modulate the sensitivity of tumor necrosis factor-related apoptosis-inducing ligand-resistant bladder tumor cells
    • Earel J.K., VanOosten R.L., Griffith T.S. Histone deacetylase inhibitors modulate the sensitivity of tumor necrosis factor-related apoptosis-inducing ligand-resistant bladder tumor cells. Cancer Res. 2006, 66:499-507.
    • (2006) Cancer Res. , vol.66 , pp. 499-507
    • Earel, J.K.1    VanOosten, R.L.2    Griffith, T.S.3
  • 20
    • 2942584501 scopus 로고    scopus 로고
    • Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells
    • Rosato R.R., Almenara J.A., Dai Y., Grant S. Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells. Mol. Cancer Ther. 2003, 2:1273-1284.
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 1273-1284
    • Rosato, R.R.1    Almenara, J.A.2    Dai, Y.3    Grant, S.4
  • 21
    • 14844345670 scopus 로고    scopus 로고
    • Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts
    • Vanoosten R.L., Moore J.M., Ludwig A.T., Griffith T.S. Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts. Mol. Ther. 2005, 11:542-552.
    • (2005) Mol. Ther. , vol.11 , pp. 542-552
    • Vanoosten, R.L.1    Moore, J.M.2    Ludwig, A.T.3    Griffith, T.S.4
  • 22
    • 69849094949 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8
    • Hacker S., Dittrich A., Mohr A., Schweitzer T., Rutkowski S., Krauss J., Debatin K.M., Fulda S. Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8. Oncogene 2009, 28:3097-3110.
    • (2009) Oncogene , vol.28 , pp. 3097-3110
    • Hacker, S.1    Dittrich, A.2    Mohr, A.3    Schweitzer, T.4    Rutkowski, S.5    Krauss, J.6    Debatin, K.M.7    Fulda, S.8
  • 23
    • 84889271499 scopus 로고    scopus 로고
    • IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway
    • Fulda S., Debatin K.M. IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway. Oncogene 2002, 21:2295-2308.
    • (2002) Oncogene , vol.21 , pp. 2295-2308
    • Fulda, S.1    Debatin, K.M.2
  • 24
    • 33645239495 scopus 로고    scopus 로고
    • HDAC inhibitor treatment of hepatoma cells induces both TRAIL-independent apoptosis and restoration of sensitivity to TRAIL
    • Pathil A., Armeanu S., Venturelli S., Mascagni P., Weiss T.S., Gregor M., Lauer U.M., Bitzer M. HDAC inhibitor treatment of hepatoma cells induces both TRAIL-independent apoptosis and restoration of sensitivity to TRAIL. Hepatology 2006, 43:425-434.
    • (2006) Hepatology , vol.43 , pp. 425-434
    • Pathil, A.1    Armeanu, S.2    Venturelli, S.3    Mascagni, P.4    Weiss, T.S.5    Gregor, M.6    Lauer, U.M.7    Bitzer, M.8
  • 25
    • 0038494686 scopus 로고    scopus 로고
    • Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein
    • Aron J.L., Parthun M.R., Marcucci G., Kitada S., Mone A.P., Davis M.E., Shen T., Murphy T., Wickham J., Kanakry C., Lucas D.M., Reed J.C., Grever M.R., Byrd J.C. Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein. Blood 2003, 102:652-658.
    • (2003) Blood , vol.102 , pp. 652-658
    • Aron, J.L.1    Parthun, M.R.2    Marcucci, G.3    Kitada, S.4    Mone, A.P.5    Davis, M.E.6    Shen, T.7    Murphy, T.8    Wickham, J.9    Kanakry, C.10    Lucas, D.M.11    Reed, J.C.12    Grever, M.R.13    Byrd, J.C.14
  • 26
    • 11844298984 scopus 로고    scopus 로고
    • Sensitization of osteosarcoma cells to death receptor-mediated apoptosis by HDAC inhibitors through downregulation of cellular FLIP
    • Watanabe K., Okamoto K., Yonehara S. Sensitization of osteosarcoma cells to death receptor-mediated apoptosis by HDAC inhibitors through downregulation of cellular FLIP. Cell Death Differ. 2005, 12:10-18.
    • (2005) Cell Death Differ. , vol.12 , pp. 10-18
    • Watanabe, K.1    Okamoto, K.2    Yonehara, S.3
  • 29
    • 84891322454 scopus 로고    scopus 로고
    • Cellular FLICE-inhibitory protein: an update
    • Wiley-VCH, Heidelberg, K.M. Debatin, S. Fulda (Eds.)
    • Micheau O. Cellular FLICE-inhibitory protein: an update. Apoptosis and Cancer Therapy 2006, 120-157. Wiley-VCH, Heidelberg. K.M. Debatin, S. Fulda (Eds.).
    • (2006) Apoptosis and Cancer Therapy , pp. 120-157
    • Micheau, O.1
  • 31
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • Kroemer G., Galluzzi L., Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 2007, 87:99-163.
    • (2007) Physiol. Rev. , vol.87 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 32
    • 84856495152 scopus 로고    scopus 로고
    • Targeting IAP proteins for therapeutic intervention in cancer
    • Fulda S., Vucic D. Targeting IAP proteins for therapeutic intervention in cancer. Nat. Rev. Drug Disc 2012, 11:109-124.
    • (2012) Nat. Rev. Drug Disc , vol.11 , pp. 109-124
    • Fulda, S.1    Vucic, D.2
  • 33
    • 33845810433 scopus 로고    scopus 로고
    • Rapid and profound potentiation of Apo2L/TRAIL-mediated cytotoxicity and apoptosis in thoracic cancer cells by the histone deacetylase inhibitor trichostatin A: the essential role of the mitochondria-mediated caspase activation cascade
    • Reddy R.M., Yeow W.S., Chua A., Nguyen D.M., Baras A., Ziauddin M.F., Shamimi-Noori S.M., Maxhimer J.B., Schrump D.S. Rapid and profound potentiation of Apo2L/TRAIL-mediated cytotoxicity and apoptosis in thoracic cancer cells by the histone deacetylase inhibitor trichostatin A: the essential role of the mitochondria-mediated caspase activation cascade. Apoptosis 2007, 12:55-71.
    • (2007) Apoptosis , vol.12 , pp. 55-71
    • Reddy, R.M.1    Yeow, W.S.2    Chua, A.3    Nguyen, D.M.4    Baras, A.5    Ziauddin, M.F.6    Shamimi-Noori, S.M.7    Maxhimer, J.B.8    Schrump, D.S.9
  • 34
    • 33745822415 scopus 로고    scopus 로고
    • Valproic acid, an antiepileptic drug with histone deacetylase inhibitory activity, potentiates the cytotoxic effect of Apo2L/TRAIL on cultured thoracic cancer cells through mitochondria-dependent caspase activation
    • Ziauddin M.F., Yeow W.S., Maxhimer J.B., Baras A., Chua A., Reddy R.M., Tsai W., Cole G.W., Schrump D.S., Nguyen D.M. Valproic acid, an antiepileptic drug with histone deacetylase inhibitory activity, potentiates the cytotoxic effect of Apo2L/TRAIL on cultured thoracic cancer cells through mitochondria-dependent caspase activation. Neoplasia 2006, 8:446-457.
    • (2006) Neoplasia , vol.8 , pp. 446-457
    • Ziauddin, M.F.1    Yeow, W.S.2    Maxhimer, J.B.3    Baras, A.4    Chua, A.5    Reddy, R.M.6    Tsai, W.7    Cole, G.W.8    Schrump, D.S.9    Nguyen, D.M.10
  • 35
    • 32844465568 scopus 로고    scopus 로고
    • In vitro efficacy of AdTRAIL gene therapy of bladder cancer is enhanced by trichostatin A-mediated restoration of CAR expression and downregulation of cFLIP and Bcl-XL
    • El-Zawahry A., Lu P., White S.J., Voelkel-Johnson C. In vitro efficacy of AdTRAIL gene therapy of bladder cancer is enhanced by trichostatin A-mediated restoration of CAR expression and downregulation of cFLIP and Bcl-XL. Cancer Gene Ther. 2006, 13:281-289.
    • (2006) Cancer Gene Ther. , vol.13 , pp. 281-289
    • El-Zawahry, A.1    Lu, P.2    White, S.J.3    Voelkel-Johnson, C.4
  • 36
    • 0346725822 scopus 로고    scopus 로고
    • Sensitization of mesothelioma to TRAIL apoptosis by inhibition of histone deacetylase: role of Bcl-xL down-regulation
    • Neuzil J., Swettenham E., Gellert N. Sensitization of mesothelioma to TRAIL apoptosis by inhibition of histone deacetylase: role of Bcl-xL down-regulation. Biochem. Biophys. Res. Commun. 2004, 314:186-191.
    • (2004) Biochem. Biophys. Res. Commun. , vol.314 , pp. 186-191
    • Neuzil, J.1    Swettenham, E.2    Gellert, N.3
  • 37
    • 4444239987 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells
    • Zhang X.D., Gillespie S.K., Borrow J.M., Hersey P. The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells. Mol. Cancer Ther. 2004, 3:425-435.
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 425-435
    • Zhang, X.D.1    Gillespie, S.K.2    Borrow, J.M.3    Hersey, P.4
  • 38
    • 33845352223 scopus 로고    scopus 로고
    • Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells
    • Gillespie S., Borrow J., Zhang X.D., Hersey P. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells. Apoptosis 2006, 11:2251-2265.
    • (2006) Apoptosis , vol.11 , pp. 2251-2265
    • Gillespie, S.1    Borrow, J.2    Zhang, X.D.3    Hersey, P.4
  • 39
    • 33748887599 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio
    • Muhlethaler-Mottet A., Flahaut M., Bourloud K.B., Auderset K., Meier R., Joseph J.M., Gross N. Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. BMC Cancer 2006, 6:214.
    • (2006) BMC Cancer , vol.6 , pp. 214
    • Muhlethaler-Mottet, A.1    Flahaut, M.2    Bourloud, K.B.3    Auderset, K.4    Meier, R.5    Joseph, J.M.6    Gross, N.7
  • 40
    • 84856524861 scopus 로고    scopus 로고
    • Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy
    • Spiegel S., Milstien S., Grant S. Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy. Oncogene 2012, 31:537-551.
    • (2012) Oncogene , vol.31 , pp. 537-551
    • Spiegel, S.1    Milstien, S.2    Grant, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.