Human gastric cancer development with TNF-α-inducing protein secreted from Helicobacter pylori

Cancer Letters

Volumn 322, Issue 2, 2012, Pages 133-138

  Suganuma, Masami ^a   Watanabe, Tatsuro ^a   Yamaguchi, Kensei ^a   Takahashi, Atsushi ^a,b   Fujiki, Hirota ^c  

^a SAITAMA CANCER CENTER   (Japan)

^b SAITAMA UNIVERSITY   (Japan)

^c TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Chemokine; NF B; TNF ; Tumor promotion

Indexed keywords

ANTINEOPLASTIC AGENT; AS 1411; CANCER VACCINE; ENDOSTATIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 32; LACTOFERRIN; MIDKINE; NUCLEOLIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; CANCER RISK; CARCINOGENESIS; CELL SURFACE; CELLULAR DISTRIBUTION; CRYSTAL STRUCTURE; CYTOKINE RELEASE; DRUG TARGETING; GENE; GENE EXPRESSION; GENE FUNCTION; GENE INTERACTION; HELICOBACTER PYLORI; HUMAN; KIDNEY CARCINOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SHORT SURVEY; STOMACH CANCER; TIPALPHA GENE; TNFALPHA GENE; TRANSCRIPTION INITIATION;

HELICOBACTER PYLORI;

EID: 84861674386     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.03.027     Document Type: Review

References (45)

1. Marshall B.J., Warren J.R. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984, 1:1311-1315.
2. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans 61 (1994) 177-220.
3. Polk D.B., Peek R.M. Helicobacter pylori: gastric cancer and beyond. Nat. Rev. Cancer 2010, 10:403-414.
4. Kim S.S., Ruiz V.E., Carroll J.D., Moss S.F. Helicobacter pylori in the pathogenesis of gastric cancer and gastric lymphoma. Cancer Lett. 2011, 305:228-238.
5. Senthilkumar C., Niranjali S., Jayanthi V., Ramesh T., Devaraj H. Molecular and histological evaluation of tumor necrosis factor-α expression in Helicobacter pylori-mediated gastric carcinogenesis. J. Cancer Res. Clin. Oncol. 2011, 137:577-583.
6. Hannelien V., Karel G., Jo V.D., Sofie S. The role of CXC chemokines in the transition of chronic inflammation to esophageal and gastric cancer. Biochim. Biophys. Acta 2012, 1825:117-129.
7. Sugiyama A., Maruta F., Ikeno T., Ishida K., Kawasaki S., Katsuyama T., Shimizu N., Tatematsu M. Helicobacter pylori infection enhances N-methyl-N-nitrosourea-induced stomach carcinogenesis in the Mongolian gerbil. Cancer Res. 1998, 58:2067-2069.
8. Shimizu N., Inada K., Nakanishi H., Tsukamoto T., Ikehara Y., Kaminishi M., Kuramoto S., Sugiyama A., Katsuyama T., Tatematsu M. Helicobacter pylori infection enhances glandular stomach carcinogenesis in Mongolian gerbils treated with chemical carcinogens. Carcinogenesis 1999, 20:669-676.
9. Suganuma M., Okabe S., Marino M.W., Sakai A., Sueoka E., Fujiki H. Essential role of tumor necrosis factor α (TNF-α) in tumor promotion as revealed by TNF-α-deficient mice. Cancer Res. 1999, 59:4516-4518.
10. Suganuma M., Okabe S., Kurusu M., Iida N., Ohshima S., Saeki Y., Kishimoto T., Fujiki H. Discrete roles of cytokines, TNF-α, IL-1, IL-6 in tumor promotion and cell transformation. Int. J. Oncol. 2002, 20:131-136.
11. Suganuma M., Kurusu M., Suzuki K., Nishizono A., Murakami K., Fujioka T., Fujiki H. New tumor necrosis factor-α-inducing protein released from Helicobacter pylori for gastric cancer progression. J. Cancer Res. Clin. Oncol. 2005, 131:305-313.
12. Suganuma M., Yamaguchi K., Ono Y., Matsumoto H., Hayashi T., Ogawa T., Imai K., Kuzuhara T., Nishizono A., Fujiki H. TNF-α-inducing protein, a carcinogenic factor secreted from H. pylori, enters gastric cancer cells. Int. J. Cancer 2008, 123:117-122.
13. Suganuma M., Kuzuhara T., Yamaguchi K., Fujiki H. Carcinogenic role of tumor necrosis factor-α inducing protein of Helicobacter pylori in human stomach. J. Biochem. Mol. Biol. 2006, 39:1-8.
14. Watanabe T., Tsuge H., Imagawa T., Kise D., Hirano K., Beppu M., Takahashi A., Yamaguchi K., Fujiki H., Suganuma M. Nucleolin as cell surface receptor for tumor necrosis factor-α inducing protein: a carcinogenic factor of Helicobacter pylori. J. Cancer Res. Clin. Oncol. 2010, 136:911-921.
15. Ginisty H., Sicard H., Roger B., Bouvet P. Structure and functions of nucleolin. J. Cell Sci. 1999, 112(Pt 6):761-772.
16. Storck S., Shukla M., Dimitrov S., Bouvet P. Functions of the histone chaperone nucleolin in diseases. Subcell. Biochem. 2007, 41:125-144.
17. Hirano K., Miki Y., Hirai Y., Sato R., Itoh T., Hayashi A., Yamanaka M., Eda S., Beppu M. A multifunctional shuttling protein nucleolin is a macrophage receptor for apoptotic cells. J. Biol. Chem. 2005, 280:39284-39293.
18. Hoja-Lukowicz D., Przybylo M., Pochec E., Drabik A., Silberring J., Kremser M., Schadendorf D., Laidler P., Litynska A. The new face of nucleolin in human melanoma. Cancer Immunol. Immunother. 2009, 58:1471-1480.
19. Hovanessian A.G. Midkine, a cytokine that inhibits HIV infection by binding to the cell surface expressed nucleolin. Cell Res. 2006, 16:174-181.
20. Legrand D., Vigie K., Said E.A., Elass E., Masson M., Slomianny M.C., Carpentier M., Briand J.P., Mazurier J., Hovanessian A.G. Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells. Eur. J. Biochem. 2004, 271:303-317.
21. Reyes-Reyes E.M., Akiyama S.K. Cell-surface nucleolin is a signal transducing P-selectin binding protein for human colon carcinoma cells. Exp. Cell Res. 2008, 314:2212-2223.
22. Watanabe T., Hirano K., Takahashi A., Yamaguchi K., Beppu M., Fujiki H., Suganuma M. Nucleolin on the cell surface as a new molecular target for gastric cancer treatment. Biol. Pharm. Bull. 2010, 33:796-803.
23. Suganuma M., Kurusu M., Okabe S., Sueoka N., Yoshida M., Wakatsuki Y., Fujiki H. Helicobacter pylori membrane protein 1: a new carcinogenic factor of Helicobacter pylori. Cancer Res. 2001, 61:6356-6359.
24. Kawai M., Furuta Y., Yahara K., Tsuru T., Oshima K., Handa N., Takahashi N., Yoshida M., Azuma T., Hattori M., Uchiyama I., Kobayashi I. Evolution in an oncogenic bacterial species with extreme genome plasticity: Helicobacter pylori East Asian genomes. BMC Microbiol. 2011, 11:104.
25. Godlewska R., Pawlowski M., Dzwonek A., Mikula M., Ostrowski J., Drela N., Jagusztyn-Krynicka E.K. Tip-α (hp0596 gene product) is a highly immunogenic Helicobacter pylori protein involved in colonization of mouse gastric mucosa. Curr. Microbiol. 2008, 56:279-286.
26. Tsuge H., Tsurumura T., Utsunomiya H., Kise D., Kuzuhara T., Watanabe T., Fujiki H., Suganuma M. Structural basis for the Helicobacter pylori-carcinogenic TNF-α-inducing protein. Biochem. Biophys. Res. Commun. 2009, 388:193-198.
27. Tosi T., Cioci G., Jouravleva K., Dian C., Terradot L. Structures of the tumor necrosis factor α inducing protein Tipα: a novel virulence factor from Helicobacter pylori. FEBS Lett. 2009, 583:1581-1585.
28. Jang J.Y., Yoon H.J., Yoon J.Y., Kim H.S., Lee S.J., Kim K.H., Kim do J., Jang S., Han B.G., Lee B.I., Suh S.W. Crystal structure of the TNF-α-inducing protein (Tipα) from Helicobacter pylori: insights into its DNA-binding activity. J. Mol. Biol. 2009, 392:191-197.
29. Chouard T. Structural biology: breaking the protein rules. Nature 2011, 471:151-153.
30. Kuzuhara T., Suganuma M., Kurusu M., Fujiki H. Helicobacter pylori-secreting protein Tipα is a potent inducer of chemokine gene expressions in stomach cancer cells. J. Cancer Res. Clin. Oncol. 2007, 133:287-296.
31. Richmond A. NF-κB, chemokine gene transcription and tumour growth. Nat. Rev. Immunol. 2002, 2:664-674.
32. Balkwill F. Cancer and the chemokine network. Nat. Rev. Cancer 2004, 4:540-550.
33. Kuzuhara T., Suganuma M., Oka K., Fujiki H. DNA-binding activity of TNF-α inducing protein from Helicobacter pylori. Biochem. Biophys. Res. Commun. 2007, 362:805-810.
34. Carpentier M., Morelle W., Coddeville B., Pons A., Masson M., Mazurier J., Legrand D. Nucleolin undergoes partial N- and O-glycosylations in the extranuclear cell compartment. Biochemistry 2005, 44:5804-5815.
35. Losfeld M.E., Khoury D.E., Mariot P., Carpentier M., Krust B., Briand J.P., Mazurier J., Hovanessian A.G., Legrand D. The cell surface expressed nucleolin is a glycoprotein that triggers calcium entry into mammalian cells. Exp. Cell Res. 2009, 315:357-369.
36. Farin K., Schokoroy S., Haklai R., Cohen-Or I., Elad-Sfadia G., Reyes-Reyes M.E., Bates P.J., Cox A.D., Kloog Y., Pinkas-Kramarski R. Oncogenic synergism between ErbB1, nucleolin, and mutant Ras. Cancer Res. 2011, 71:2140-2151.
37. Said E.A., Krust B., Nisole S., Svab J., Briand J.P., Hovanessian A.G. The anti-HIV cytokine midkine binds the cell surface-expressed nucleolin as a low affinity receptor. J. Biol. Chem. 2002, 277:37492-37502.
38. Shi H., Huang Y., Zhou H., Song X., Yuan S., Fu Y., Luo Y. Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin. Blood 2007, 110:2899-2906.
39. Nisole S., Said E.A., Mische C., Prevost M.C., Krust B., Bouvet P., Bianco A., Briand J.P., Hovanessian A.G. The anti-HIV pentameric pseudopeptide HB-19 binds the C-terminal end of nucleolin and prevents anchorage of virus particles in the plasma membrane of target cells. J. Biol. Chem. 2002, 277:20877-20886.
40. Tayyari F., Marchant D., Moraes T.J., Duan W., Mastrangelo P., Hegele R.G. Identification of nucleolin as a cellular receptor for human respiratory syncytial virus. Nat. Med. 2011, 17:1132-1135.
41. Okuda M., Nakazawa T., Yamauchi K., Miyashiro E., Koizumi R., Booka M., Teraguchi S., Tamura Y., Yoshikawa N., Adachi Y., Imoto I. Bovine lactoferrin is effective to suppress Helicobacter pylori colonization in the human stomach: a randomized, double-blind, placebo-controlled study. J. Infect. Chemother. 2005, 11:265-269.
42. Di Mario F., Aragona G., Dal Bo N., Cavallaro L., Marcon V., Olivieri P., Benedetti E., Orzes N., Marin R., Tafner G., Chilovi F., De Bastiani R., Fedrizzi F., Franceschi M., Salvat M.H., Monica F., Piazzi L., Valiante F., Vecchiati U., Cavestro G.M., Comparato G., Iori V., Maino M., Leandro G., Pilotto A., Rugge M., Franze A. Bovine lactoferrin for Helicobacter pylori eradication: an open, randomized, multicentre study. Aliment. Pharm. Therap. 2006, 23:1235-1240.
43. Ireson C.R., Kelland L.R. Discovery and development of anticancer aptamers. Mol. Cancer Therap. 2006, 5:2957-2962.
44. Soundararajan S., Chen W., Spicer E.K., Courtenay-Luck N., Fernandes D.J. The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells. Cancer Res. 2008, 68:2358-2365.
45. Inoue K., Shiota S., Yamada K., Gotoh K., Suganuma M., Fujioka T., Ahmed K., Iha H., Nishizono A. Evaluation of a new tumor necrosis factor-α-inducing membrane protein of Helicobacter pylori as a prophylactic vaccine antigen. Helicobacter 2009, 14:135-143.