Alpha-lipoic acid protects against hydrogen peroxide-induced oxidative stress in MC3T3-E1 osteoblast-like cells

Journal of Functional Foods

Volumn 4, Issue 3, 2012, Pages 642-649

  Xiao, Ying ^a,c   Cui, Jue ^b,c   Shi, Yonghui ^c   Le, Guowei ^c  

^a SHANGHAI INSTITUTE OF TECHNOLOGY   (China)

^b XUZHOU INSTITUTE OF TECHNOLOGY   (China)

^c School of Food Science and Technology   (China)

Author keywords

Alpha lipoic acid; Antioxidant; Calcification; Hydrogen peroxide; Osteoblast

Indexed keywords

EID: 84861672298     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2012.04.004     Document Type: Article

References (45)

1. Anwar A., Siegel D., Kepa J.K., Ross D. Interaction of the molecular chaperone Hsp70 with human NAD(P)H:quinine oxidoreductase 1. Journal of Biological Chemistry 2002, 277:14060-14067.
2. Arai M., Shibata Y., Pugdee K., Abiko Y., Ogata Y. Effects of reactive oxygen species (ROS) on antioxidant system and osteoblastic differentiation in MC3T3-E1 cells. IUBMB Life 2007, 59:27-33.
3. Asher G., Lotem J., Kama R., Sachs L., Shaul Y. NQO1 stabilizes p53 through a distinct pathway. Proceedings of the National Academy of Sciences of the United States of America 2002, 99:3099-3104.
4. Basu S., Michaëlsson K., Olofsson H., Johansson S., Melhus H. Association between oxidative stress and bone mineral density. Biochemical and Biophysical Research Communications 2001, 288:275-279.
5. Bengner U., Johnell O., Redlund-Johnell I. Changes in incidence and prevalence of vertebral fractures during 30 years. Calcified Tissue International 1988, 42:293-296.
6. Bhangu P.S., Genever P.G., Spencer G.J., Grewal T.S., Skerry T.M. Evidence for targeted vesicular glutamate exocytosis in osteoblasts. Bone 2001, 29:16-23.
7. Bruder S.P., Fink D.J., Caplan A.I. Mesenchymal stem cellsin bone development bone repair, and skeletal regenerationtherapy. Journal of Cellular Biochemistry 1994, 56:283-294.
8. Busse E., Zimmer G., Schopohl B., Kornhuber B. Influence of alpha-lipoic acid on intracellular glutathione in vitro and in vivo. Arzneimittelforschung 1992, 42:829-831.
9. Carmichael J., DeGraff W.G., Gazdar A.F., Minna J.D., Mitchell J.B. Evaluation of a tetrazolium-based semiautomated colori-metric assay. Assessment of chemosensitivity testing. Cancer Research 1987, 47:936-942.
10. Chen J.-H., Stoeber K., Kingsbury S., Ozanne S.E., Williams G.H., Hales C.N. Loss of proliferative capacity and induction of senescence in oxidatively stressed human fibrobolasts. Journal of Biological Chemistry 2004, 279:49439-49446.
11. D'Amelio P., Cristofaro M.A., Tamone C., Morra E., Di Bella S., Isaia G., Grimaldi A., Gennero L., Gariboldi A., Ponzetto A., Pescarmona G.P., Isaia G.C. Role of iron metabolism and oxidative damage in postmenopausal bone loss. Bone 2008, 43:1010-1015.
12. Della Croce C., Bronzetti G., Cini M., Caltavuturo L., Poi G. Protective effect of lipoic acid against hydrogen peroxide in yeast cells. Toxicol In Vitro 2003, 17:753-759.
13. Ergen H.A., Gormus U., Narter F., Zeybek U., Bulgurcuoglu S., Isbir T. Investigation of NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T polymorphism in prostate cancer. Anticancer Research 2007, 27:4107-4110.
14. Fatokun A.A., Stone T.W., Smith R.A. Hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells. The effects of glutamate and protection by purines. Bone 2006, 39:542-551.
15. Flavia N.I., Mike F.Q., Cristina S. Lipoic acid. A unique antioxidant in the detoxification of activated oxygen species. Plant Physiology and Biochemistry 2002, 40:463-470.
16. Gangoiti M.V., Cortizo A.M., Arnol V., Felice J.I., McCarthy A.D. Opposing effects of bisphosphonates and advanced glycation end-products on osteoblastic cells. European Journal of Pharmacology 2008, 600:140-147.
17. Garrett I.R., Boyce B.F., Oretto R.O., Bonewald L., Poser J., Mundy G.R. Oxygen derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. Journal of Clinical Investigation 1990, 85:632-639.
18. Hamada Y., Fujii H., Kitazawa R., Yodoi J., Kitazawa S., Fukagawa M. Thioredoxin-1 overexpression in transgenic mice attenuates streptozotocin-induced diabetic osteopenia. A novel role of oxidative stress and therapeutic implications. Bone 2009, 44:936-941.
19. Hinoi E., Fujimori S., Wang L., Hojo H., Uno K., Yoneda Y. Nrf2 negatively regulates osteoblast differentiation via interfering with Runx2-dependent transcriptional activation. Journal of Biological Chemistry 2006, 281:18015-18024.
20. Isomura H., Fujie K., Shibata K., Inoue N., Iizuka T., Takebe G., Takahashi K., Nishihira J., Izumi H., Sakamoto W. Bone metabolism and oxidative stress in postmenopausal rats with iron overload. Toxicology 2004, 197:93-100.
21. Kelepouris N., Harper K.D., Gannon F., Kaplan F.S., Haddad J.G. Severe osteoporosis in men. Annals of Internal Medicine 1995, 123:452-460.
22. Kim H.J., Chang E.J., Kim H.M., Lee S.B., Kim H.D., Su Kim G., Kim H.H. Antioxidant alpha-lipoic acid inhibits osteoclast differentiation by reducing nuclear factor-kappaB DNA binding and prevents in vivo bone resorption induced by receptor activator of nuclear factor-kappaB ligand and tumor necrosis factor-alpha. Free Radical & Biology Medicine 2006, 40:1483-1493.
23. Kwan Tat S., Padrines M., Théoleyre S., Heymann D., Fortun Y. IL-6, RANKL, TNF-alpha/IL-1. Interrelations in bone resorption pathophysiology. Cytokine & Growth Factor Reviews 2004, 15:49-60.
24. Lean J.M., Davies J.T., Fuller K., Jagger C.J., Kirstein B., Partington G.A., Urry Z.L., Chambers T.J. A crucial role for thiol antioxidants in estrogen-deficiency bone loss. Journal of Clinical Investigation 2003, 112:915-923.
25. Lean J.M., Jagger C.J., Kirstein B., Fuller K., Chambers T.J. Hydrogen peroxide is essential for estrogen-deficiency bone loss and osteoclast formation. Endocrinology 2005, 146:728-735.
26. Li Y., Zhao Y., Yu W., Jiang S. Scavenging ability on ROS of alpha-lipoic acid (ALA). Food Chemistry 2004, 84:563-567.
27. Liu Z.H., Zhao Y.L., Ding G.Z., Zhou Y. Epidemiology of primary osteoporosis in China. International Osteoporosis 1997, 7:S84-S87.
28. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
29. Mishra K.P. Cell membrane oxidative damage induced by gamma-radiation and apoptotic sensitivity. Journal of Environmental Pathology, Toxicology and Oncology 2004, 23:2361-2366.
30. Morton D.J., Barrett-Connor E.L., Schneider D.L. Vitamin C supplement use and bone mineral density in postmenopausal women. Journal of Bone and Mineral Research 2001, 16:135-140.
31. Muthusami S., Ramachandran I., Muthusamy B., Vasudevan G., Prabhu V., Subramaniam V., Jagadeesan A., Narasimhan S. Ovariectomy induces oxidative stress and impairs bone antioxidant. Clinica Chimica Acta 2005, 360:81-86.
32. Noda M. Current topics in pharmacological research on bone metabolism. Regulation of bone mass by the function of endogenous modulators of bone morphogenetic protein in adult stage. Journal of Pharmacological Sciences 2006, 100:211-214.
33. Reddi A.H. Bone morphogenetic proteins, bone marrowstromal cells, and mesenchymal stem cells. Maureen Owen re-visited. Clinical Orthopaedics and Related Research 1995, 313:115-119.
34. Reed L. Multienzyme complexe. Accounts of Chemical Research 1974, 7:40-46.
35. Ross D. Functions and distribution of NQO1 in human bone marrow. Potential clues to benzene toxicity. Chemico-Biological Interactions 2005, 153-154:137-146.
36. Scott B.C., Aruoma O.I., Evans P.J., Neill C., Van der Vliet A., Cross C.E., Tritschler H., Halliwell B. Lipoic and dihydrolipoic acids as antioxidant. A critical evaluation. Free Radical Research 1994, 20:119-133.
37. Shay K.P., Moreau R.F., Smith E.J., Smith A.R., Hagen T.M. Alpha-lipoic acid as a dietary supplement. Molecular mechanisms and therapeutic potential. Biochimica et Biophysica Acta 2009, 1790:1149-1160.
38. Smith A.R., Shenvi S.V., Widlansky M., Suh J.H., Hagen T.M. Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. Current Medicinal Chemistry 2004, 11:1135-1146.
39. Sreekumar R., Unnikrishnan J., Fu A., Nygren J., Short K.R., Schimke J., Barazzoni R., Nair K.S. Impact of high-fat diet and antioxidant supplement on mitochondrial functions and gene transcripts in rat muscle. American Journal of Physiology - Endocrinology and Metabolism 2002, 282:E1055-E1061.
40. Sudo H., Kodama H., Amagai Y., Yamamoto S., Kasai S. In vitro differentiation and calcification in new clonal osteogenic cell line derived from newborn mouse calvariae. Journal of Cell Biology 1983, 96:191-198.
41. 2-derived free radicals treated fibronectin substratum reduces the bone nodule formation of rat calvarial osteoblast. Mechanisms of Ageing and Development 1997, 98:113-125.
42. Wang X., Kua H.Y., Hu Y., Guo K., Zeng Q., Wu Q., Ng H.H., Karsenty G., de Crombrugghe B., Yeh J., Li B. P53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling. Journal of Cell Biology 2006, 172:115-125.
43. Xiao Y., Cui J., Li Y.X., Shi Y.H., Le G.W. Expression of genes associated with bone resorption is increased and bone formation is decreased in mice fed a high-fat diet. Lipids 2010, 45:345-355.
44. Xiao Y., Cui J., Li Y.X., Shi Y.H., Wang B., Le G.W., Wang Z.P. Dyslipidemic high-fat diet affects adversely bone metabolism in mice associated with impaired antioxidant capacity. Nutrition 2011, 27:214-220.
45. Yang R.L., Li W., Shi Y.H., Le G.W. Lipoic acid prevents high-fat diet-induced dyslipidemia and oxidative stress. A microarray analysis. Nutrition 2008, 24:582-588.