RNAi suppression of rice endogenous storage proteins enhances the production of rice-based Botulinum neutrotoxin type A vaccine

Vaccine

Volumn 30, Issue 28, 2012, Pages 4160-4166

  Yuki, Yoshikazu ^a   Mejima, Mio ^a   Kurokawa, Shiho ^a   Hiroiwa, Tomoko ^a   Kong, Il Gyu ^a   Kuroda, Masaharu ^b   Takahashi, Yoko ^a   Nochi, Tomonori ^a   Tokuhara, Daisuke ^a   Kohda, Tomoko ^c   Kozaki, Shunji ^c   Kiyono, Hiroshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b FOOD RESEARCH INSTITUTE   (Japan)

^c Osaka Prefecture University   (Japan)

Author keywords

Botulinum neutrotoxin; MucoRice; Nasal vaccine; Rice; RNAi

Indexed keywords

BOTULINUM TOXIN A; GLUTENIN; IMMUNOLOGICAL ADJUVANT; MUCORICE BOHC; PROLAMIN; SEED STORAGE PROTEIN; UNCLASSIFIED DRUG; VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; BOTULISM; CONTROLLED STUDY; DRUG EFFECT; DRUG RESPONSE; GENE REPRESSION; IMMUNOGENICITY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; TREATMENT OUTCOME; VACCINE PRODUCTION;

ANIMALS; BACTERIAL VACCINES; BOTULINUM TOXINS, TYPE A; BOTULISM; DISEASE MODELS, ANIMAL; GENE SILENCING; GLUTENS; MICE; ORYZA SATIVA; PLANTS, GENETICALLY MODIFIED; PROLAMINS; RNA, ANTISENSE; SEED STORAGE PROTEINS;

EID: 84861660825     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.04.064     Document Type: Article

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