A detailed view of microparticle formation by in-process monitoring of the glass transition temperature

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 81, Issue 2, 2012, Pages 399-408

  Vay, Kerstin ^a   Frieß, Wolfgang ^b   Scheler, Stefan ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Drug release; Glass transition temperature; Microspheres; PLGA; Solvent evaporation

Indexed keywords

ALCOHOL; DICHLOROMETHANE; MICROSPHERE; POLYGLACTIN; POLYMER;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DIFFUSION; DRUG RELEASE; ENCAPSULATION; GLASS TRANSITION TEMPERATURE; MOLECULAR WEIGHT; PARTICLE SIZE; PROCESS MONITORING; SOLVENT EFFECT; SOLVENT EXTRACTION;

DRUG CARRIERS; EMULSIONS; GLASS; KINETICS; LACTIC ACID; MICROSPHERES; MOLECULAR WEIGHT; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; SOLVENTS; TEMPERATURE; TRANSITION TEMPERATURE;

EID: 84861610918     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.02.019     Document Type: Article

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