14-3-3ε is required for germ cell migration in drosophila

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Tsigkari, K Kirki ^a   Acevedo, Summer F ^a,b   Skoulakis, Efthimios M C ^a  

^a BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

^b PONCE SCHOOL OF MEDICINE   (Puerto Rico)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN 14 3 3; PROTEIN 14 3 3 EPSILON; PROTEIN ZFH 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; REPRESSOR PROTEIN; ZFH1 PROTEIN, DROSOPHILA;

14 3 3 EPSILON GENE; ARTICLE; CELL COUNT; CELL MIGRATION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; FEMALE; GENE; GERM CELL; GONAD; HOMOZYGOTE; LEO GENE; LOSS OF FUNCTION MUTATION; MALE; MESODERM; NONHUMAN; PHENOTYPE; POLAR BODY; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SOMATIC CELL; TRANSCRIPTION REGULATION; AMINO ACID SEQUENCE; ANIMAL; ANIMAL EMBRYO; CELL MOTION; CHEMISTRY; CLASSIFICATION; CYTOLOGY; DROSOPHILA MELANOGASTER; GENE DELETION; GENETICS; METABOLISM; MOLECULAR GENETICS; OOCYTE; PRENATAL DEVELOPMENT; PROTEIN STABILITY; SPERMATOZOON;

14-3-3 PROTEINS; AMINO ACID SEQUENCE; ANIMALS; CELL MOVEMENT; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; FEMALE; GENE DELETION; MALE; MOLECULAR SEQUENCE DATA; OVUM; PROTEIN STABILITY; REPRESSOR PROTEINS; SPERMATOZOA;

EID: 84861597354     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036702     Document Type: Article

References (44)

1. Wang W, Shakes DC, (1996) Molecular evolution of the 14-3-3 protein family. J Mol Evol 43: 384-398.
2. Ferl RJ, Manak MS, Reyes MF, (2002) The 14-3-3s. Genome Biol 3: REVIEWS3010.
3. Gardino AK, Smerdon SJ, Yaffe MB, (2006) Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of all human 14-3-3 isoforms. Semin Cancer Biol 16: 173-182.
4. Skoulakis EM, Davis RL, (1998) 14-3-3 proteins in neuronal development and function. Mol Neurobiol 16: 269-284.
5. Aitken A, Collinge DB, van Heusden BP, Isobe T, Roseboom PH, et al. (1992) 14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteins. Trends Biochem Sci 17: 498-501.
6. Morrison DK, (2009) The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development. Trends Cell Biol 19: 16-23.
7. van Hemert MJ, Steensma HY, van Heusden GP, (2001) 14-3-3 proteins: key regulators of cell division, signalling and apoptosis. Bioessays 23: 936-946.
8. Yaffe MB, (2002) How do 14-3-3 proteins work? - Gatekeeper phosphorylation and the molecular anvil hypothesis. FEBS Lett 513: 53-57.
9. Cahill CM, Tzivion G, Nasrin N, Ogg S, Dore J, et al. (2001) Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways. J Biol Chem 276: 13402-13410.
10. Dalal SN, Yaffe MB, DeCaprio JA, (2004) 14-3-3 family members act coordinately to regulate mitotic progression. Cell Cycle 3: 672-677.
11. Mils V, Baldin V, Goubin F, Pinta I, Papin C, et al. (2000) Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase. Oncogene 19: 1257-1265.
12. Messaritou G, Leptourgidou F, Franco M, Skoulakis EMC, (2009) A third functional isoform enriched in mushroom body neurons is encoded by the Drosophila 14-3-3zeta gene. FEBS Lett 583: 2934-2938.
13. Acevedo SF, Tsigkari KK, Grammenoudi S, Skoulakis EMC, (2007) In Vivo Functional Specificity and Homeostasis of Drosophila 14-3-3 Proteins. Genetics 177: 239-253.
14. Chang HC, Rubin GM, (1997) 14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila. Genes Dev 11: 1132-1139.
15. Philip N, Acevedo SF, Skoulakis EM, (2001) Conditional rescue of olfactory learning and memory defects in mutants of the 14-3-3zeta gene leonardo. J Neurosci 21: 8417-8425.
16. Su TT, Parry DH, Donahoe B, Chien CT, O'Farrell PH, et al. (2001) Cell cycle roles for two 14-3-3 proteins during Drosophila development. J Cell Sci 114: 3445-3454.
17. Kockel L, Vorbruggen G, Jackle H, Mlodzik M, Bohmann D, (1997) Requirement for Drosophila 14-3-3 zeta in Raf-dependent photoreceptor development. Genes Dev 11: 1140-1147.
18. Blackwell TK, (2004) Germ cells: finding programs of mass repression. Curr Biol 14: 229-230.
19. Reichman-Fried M, Minina S, Raz E, (2004) Autonomous modes of behavior in primordial germ cell migration. Dev Cell 6: 589-596.
20. Callaini G, Riparbelli MG, Dallai R, (1995) Pole cell migration through the gut wall of the Drosophila embryo: analysis of cell interactions. Dev Biol 170: 365-375.
21. Santos AC, Lehmann R, (2004) Germ Cell Specification and Migration in Drosophila and beyond. Current Biology 14: R578-R589.
22. Moore LA, Broihier HT, Van Doren M, Lunsford LB, Lehmann R, (1998) Identification of genes controlling germ cell migration and embryonic gonad formation in Drosophila. Development 125: 667-678.
23. Mershin A, Pavlopoulos E, Fitch O, Braden BC, Nanopoulos DV, et al. (2004) Learning and memory deficits upon TAU accumulation in Drosophila mushroom body neurons. Learn Mem 11: 277-287.
24. Wylie C, (1999) Germ cells. Cell 96: 165-174.
25. Wylie C, (2000) Germ cells. Curr Opin Genet Dev 10: 410-413.
26. Broadie K, Rushton E, Skoulakis EM, Davis RL, (1997) Leonardo, a Drosophila 14-3-3 protein involved in learning, regulates presynaptic function. Neuron 19: 391-402.
27. Jaglarz MK, Howard KR, (1995) The active migration of Drosophila primordial germ cells. Development 121: 3495-3503.
28. Reuter R, (1994) The gene serpent has homeotic properties and specifies endoderm versus ectoderm within the Drosophila gut. Development 120: 1123-1135.
29. Warrior R, (1994) Primordial germ cell migration and the assembly of the Drosophila embryonic gonad. Dev Biol 166: 180-194.
30. Zhang N, Zhang J, Purcell KJ, Cheng Y, Howard K, (1997) The Drosophila protein Wunen repels migrating germ cells. Nature 385: 64-67.
31. Broihier HT, Moore LA, Van Doren M, Newman S, Lehmann R, (1998) zfh-1 is required for germ cell migration and gonadal mesoderm development in Drosophila. Development 125: 655-666.
32. Boyle M, Bonini N, DiNardo S, (1997) Expression and function of clift in the development of somatic gonadal precursors within the Drosophila mesoderm. Development 124: 971-982.
33. Stallock J, Molyneaux K, Schaible K, Knudson CM, Wylie C, (2003) The pro-apoptotic gene Bax is required for the death of ectopic primordial germ cells during their migration in the mouse embryo. Development 130: 6589-6597.
34. Boyle M, DiNardo S, (1995) Specification, migration and assembly of the somatic cells of the Drosophila gonad. Development. 121: 1815-1825.
35. Benton R, Palacios IM, St Johnston D, (2002) Drosophila 14-3-3/PAR5 in an essential mediator of PAR-1 function in axis formation. Dev Cell 3: 659-671.
36. Morrison SJ, Spradling AC, (2008) Stem Cells and Niches: Mechanisms that promote stem cell maintenance throughtout life. Cell 132: 598-611.
37. Bogenrieder T, Herlyn M, (2003) Axis of evil: Molecular mechanisms of cancer metastasis. Oncogene 42: 6524-6536.
38. Moore MA, (2001) The role of chemoattraction in cancer metastases. Bioessays. 23: 674-676.
39. Rudolph T, Lu B, Westphal T, Szidonya J, Eissenberg J, et al. (1999) New type of CyO and TM3 green balancers. D I S 82: 99-100.
40. Brand AH, Perrimon N, (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
41. Sokal RR, Rohlf FJ, (1981) Biometry The Principles and Practice of Statistics in Biological Research. New York W. H. Freeman.
42. Li W, Skoulakis EMC, Davis RL, Perrimon N, (1997) The Drosophila 14-3-3 protein Leonardo enhances Torso signaling through D-Raf in aRas 1-dependent manner. Development 124: 4163-4171.
43. Tsichritzis T, Gaentzsch PC, Kosmidis S, Brown AE, Skoulakis EM, et al. (2007) A Drosophila ortholog of the human cylindromatosis tumor suppressor gene regulates triglyceride content and antibacterial defense. Development 177: 89-100.
44. Philip N, Acevedo SF, Skoulakis EM, (2001) Conditional rescue of olfactory learning and memory defects in mutants of the 14-3-3zeta gene leonardo. J Neurosci 21: 8417-8425.