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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 12, 2012, Pages 4049-4054

Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13

(8) Yu, Mi Sun a Lee, June b Lee, Jin Moo a Kim, Younggyu c Chin, Young Won d Jee, Jun Goo e Keum, Young Sam d Jeong, Yong Joo a

a Kookmin University (South Korea)

b Dongguk University (South Korea)

c Seoul National University (South Korea)

d Dongguk University (South Korea)

e Kyungpook National University (South Korea)

Author keywords

Myricetin; SARS coronavirus (SARS CoV) helicase; Scutellarein

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ALPHA AMYRIN; AMENTOFLAVONE; AURANTIIN; BAICALEIN; BETULIC ACID; CHRYSIN; CURCUMIN; DAIDZIN; DAUCOSTEROL; DNA; DOUBLE STRANDED DNA; FRIEDELIN; GALANGIN; HELICASE; HEPATITIS C VIRUS HELICASE; HYPERIN; ICARIIN; ISOLIQUIRITIGENIN; MYRICETIN; NARINGENIN; OLEANOLIC ACID; SARS CORONAVIRUS HELICASE; SCUTELLAREIN; SCUTELLARIN; SILYMARIN; SITOSTEROL; STIGMASTEROL; UNCLASSIFIED DRUG; URSOLIC ACID;

ARTICLE; COLORIMETRY; CONTROLLED STUDY; DRUG IDENTIFICATION; ENZYME ACTIVITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; HYDROLYSIS; SARS CORONAVIRUS;

ADENOSINE TRIPHOSPHATE; ANTIVIRAL AGENTS; APIGENIN; BREAST; CELL LINE; CELL PROLIFERATION; COLORIMETRY; DNA; DNA HELICASES; EPITHELIAL CELLS; FEMALE; FLAVONOIDS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEPACIVIRUS; HUMANS; HYDROLYSIS; INHIBITORY CONCENTRATION 50; KINETICS; METHYLTRANSFERASES; SARS VIRUS; SPECIES SPECIFICITY; VIRAL PROTEINS;

HEPATITIS C VIRUS; SARS CORONAVIRUS;

EID: 84861570338 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.04.081 Document Type: Article

Times cited : (395)

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