Remote effects of hippocampal sclerosis on effective connectivity during working memory encoding: A case of connectional diaschisis?

Cerebral Cortex

Volumn 22, Issue 6, 2012, Pages 1225-1236

  Campo, Pablo ^a,b   Garrido, Marta I ^c   Moran, Rosalyn J ^c   Maestú, Fernando ^b   García Morales, Irene ^d,e   Gil Nagel, Antonio ^e   Del Pozo, Francisco ^b   Dolan, Raymond J ^c   Friston, Karl J ^c  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^e HOSPITAL RUBER INTERNACIONAL   (Spain)

Author keywords

dynamic causal modeling; effective connectivity; magnetoencephalography; temporal lobe epilepsy; working memory

Indexed keywords

ADULT; ARTICLE; BRAIN DAMAGE; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; EPISODIC MEMORY; FEMALE; FRONTAL CORTEX; HIPPOCAMPAL SCLEROSIS; HUMAN; INFERIOR TEMPORAL CORTEX; MAGNETOENCEPHALOGRAPHY; MALE; PRIORITY JOURNAL; TEMPORAL LOBE; TEMPORAL LOBE EPILEPSY; VERBAL MEMORY; WORKING MEMORY;

ADULT; EPILEPSY, TEMPORAL LOBE; FEMALE; HIPPOCAMPUS; HUMANS; MAGNETOENCEPHALOGRAPHY; MALE; MEMORY, SHORT-TERM; NEURAL PATHWAYS; PHOTIC STIMULATION; PSYCHOMOTOR PERFORMANCE; SCLEROSIS; YOUNG ADULT;

EID: 84861550575     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhr201     Document Type: Article

References (118)

1. Abrahams S, Morris RG, Polkey CE, Jarosz JM, Cox TC, Graves M, Pickering A. 1999. Hippocampal involvement in spatial and working memory: a structural MRI analysis of patients with unilateral mesial temporal lobe sclerosis. Brain Cogn. 41:39-65.
2. Addis DR, Moscovitch M, McAndrews MP. 2007. Consequences of hippocampal damage across the autobiographical memory network in left temporal lobe epilepsy. Brain. 130:2327-2342.
3. Aldenkamp AP, Arends J, Bootsma HP, Diepman L, Hulsman J, Lambrechts D, Leenen L, Majoie M, Schellekens A, de Vocht J. 2002. Randomized double-blind parallel-group study comparing cognitive effects of a low-dose lamotrigine with valproate and placebo in healthy volunteers. Epilepsia. 43:19-26.
4. Algarabel S. 1996. Indices de interes psicolingüstico de 1917 palabras castellanas. Cognitiva. 8:43-88.
5. Axmacher N, Mormann F, Fernandez G, Cohen MX, Elger CE, Fell J. 2007. Sustained neural activity patterns during working memory in the human medial temporal lobe. J Neurosci. 27:7807-7816.
6. Axmacher N, Schmitz DP, Wagner T, Elger CE, Fell J. 2008. Interactions between medial temporal lobe, prefrontal cortex, and inferior temporal regions during visual working memory: a combined intracranial EEG and functional magnetic resonance imaging study. J Neurosci. 28:7304-7312.
7. Bai F, Zhang Z, Watson DR, Yu H, Shi Y, Yuan Y, Zang Y, Zhu C, Qian Y. 2009. Abnormal functional connectivity of hippocampus during episodic memory retrieval processing network in amnestic mild cognitive impairment. Biol Psychiatry. 65:951-958.
8. Baxendale S, Heaney D, Thompson PJ, Duncan JS. 2010. Cognitive consequences of childhood-onset temporal lobe epilepsy across the adult lifespan. Neurology. 75:705-711.
9. Benetti S, Mechelli A, Picchioni M, Broome M, Williams S, McGuire P. 2009. Functional integration between the posterior hippocampus and prefrontal cortex is impaired in both first episode schizophrenia and the at risk mental state. Brain. 132:2426-2436.
10. Bettus G, Guedj E, Joyeux F, Confort-Gouny S, Soulier E, Laguitton V, Cozzone PJ, Chauvel P, Ranjeva JP, Bartolomei F, et al. 2009. Decreased basal fMRI functional connectivity in epileptogenic networks and contralateral compensatory mechanisms. Hum Brain Mapp. 30:1580-1591.
11. Bettus G, Wendling F, Guye M, Valton L, Regis J, Chauvel P, Bartolomei F. 2008. Enhanced EEG functional connectivity in mesial temporal lobe epilepsy. Epilepsy Res. 81:58-68.
12. Bitan T, Booth JR, Choy J, Burman DD, Gitelman DR, Mesulam MM. 2005. Shifts of effective connectivity within a language network during rhyming and spelling. J Neurosci. 25:5397-5403.
13. Bocquillon P, Dujardin K, Betrouni N, Phalempin V, Houdayer E, Bourriez JL, Derambure P, Szurhaj W. 2009. Attention impairment in temporal lobe epilepsy: a neurophysiological approach via analysis of the P300 wave. Hum Brain Mapp. 30:2267-2277.
14. Bressler SL, Menon V. 2010. Large-scale brain networks in cognition: emerging methods and principles. Trends Cogn Sci. 14:277-290.
15. Brown GG, Eyler LT. 2006. Methodological and conceptual issues in functional magnetic resonance imaging: applications to schizophrenia research. Annu Rev Clin Psychol. 2:51-81.
16. Bullmore E, Sporns O. 2009. Complex brain networks: graph theoretical analysis of structural and functional systems. Nat Rev Neurosci. 10:186-198.
17. Cabeza R, Dolcos F, Graham R, Nyberg L. 2002. Similarities and differences in the neural correlates of episodic memory retrieval and working memory. Neuroimage. 16:317-330.
18. Campo P, Maestu F, Garcia-Morales I, Gil-Nagel A, Strange B, Morales M, Ortiz T. 2009. Modulation of medial temporal lobe activity in epilepsy patients with hippocampal sclerosis during verbal working memory. J Int Neuropsychol Soc. 15:536-546.
19. Campo P, Maestu F, Ortiz T, Capilla A, Fernandez S, Fernandez A. 2005. Is medial temporal lobe activation specific for encoding long-term memories? Neuroimage. 25:34-42.
20. Canevini MP, De Sarro G, Galimberti CA, Gatti G, Licchetta L, Malerba A, Muscas G, La Neve A, Striano P, Perucca E. 2010. Relationship between adverse effects of antiepileptic drugs, number of coprescribed drugs, and drug load in a large cohort of consecutive patients with drug-refractory epilepsy. Epilepsia. 51:797-804.
21. Chen Q, Wu X, Zhou B, Lui S, Tang HH, Gong QY, Shang H, Yan B, Zhou D. 2009. Functional connectivity changes in frontal-hippocampus circuity after withdrawal of topiramate in epilepsy patients. 28th International Epilepsy Congress; 28th June-2nd July; Budapest. Available from: www. epilepsybudapest2009.org.
22. Daunizeau J, David O, Stephan KE. Forthcoming. Dynamic causal modelling: a critical review of the biophysical and statistical foundations. Neuroimage.
23. Davachi L, Wagner AD. 2002. Hippocampal contributions to episodic encoding: insights from relational and item-based learning. J Neurophysiol. 88:982-990.
24. David O. 2007. Dynamic causal models and autopoietic systems. Biol Res. 40:487-502.
25. David O, Friston KJ. 2003. A neural mass model for MEG/EEG: coupling and neuronal dynamics. Neuroimage. 20:1743-1755.
26. David O, Kiebel SJ, Harrison LM, Mattout J, Kilner JM, Friston KJ. 2006. Dynamic causal modeling of evoked responses in EEG and MEG. Neuroimage. 30:1255-1272.
27. Dupont S, Van de Moortele PF, Samson S, Hasboun D, Poline JB, Adam C, Lehericy S, Le Bihan D, Samson Y, Baulac M. 2000. Episodic memory in left temporal lobe epilepsy: a functional MRI study. Brain. 123(Pt 8):1722-1732.
28. Ezzyat Y, Olson IR. 2008. The medial temporal lobe and visual working memory: comparisons across tasks, delays, and visual similarity. Cogn Affect Behav Neurosci. 8:32-40.
29. Felleman DJ, Van Essen DC. 1991. Distributed hierarchical processing in the primate cerebral cortex. Cereb Cortex. 1:1-47.
30. Fiebach CJ, Friederici AD, Smith EE, Swinney D. 2007. Lateral inferotemporal cortex maintains conceptual-semantic representations in verbal working memory. J Cogn Neurosci. 19:2035-2049.
31. Fiebach CJ, Rissman J, D'Esposito M. 2006. Modulation of inferotemporal cortex activation during verbal working memory maintenance. Neuron. 51:251-261.
32. Fingelkurts AA, Kivisaari R, Pekkonen E, Ilmoniemi RJ, Kahkonen S. 2004. Enhancement of GABA-related signalling is associated with increase of functional connectivity in human cortex. Hum Brain Mapp. 22:27-39.
33. Frings L, Schulze-Bonhage A, Spreer J, Wagner K. 2009. Remote effects of hippocampal damage on default network connectivity in the human brain. J Neurol. 256:2021-2029.
34. Friston K. 2009. Causal modelling and brain connectivity in functional magnetic resonance imaging. PLoS Biol. 7:220-225.
35. Friston K, Harrison L, Daunizeau J, Kiebel S, Phillips C, Trujillo-Barreto N, Henson R, Flandin G, Mattout J. 2008. Multiple sparse priors for the M/EEG inverse problem. Neuroimage. 39:1104-1120.
36. Friston KJ, Harrison L, Penny W. 2003. Dynamic causal modelling. Neuroimage. 19:1273-1302.
37. Friston KJ, Price CJ. 2001. Dynamic representations and generative models of brain function. Brain Res Bull. 54:275-285.
38. Furl N, van Rijsbergen NJ, Kiebel SJ, Friston KJ, Treves A, Dolan RJ. 2010. Modulation of perception and brain activity by predictable trajectories of facial expressions. Cereb Cortex. 20:694-703.
39. Fuster JM. 1990. Inferotemporal units in selective visual attention and short-term memory. J Neurophysiol. 64:681-697.
40. Fuster JM. 1995. Memory in the cerebral cortex. Cambridge: MIT Press.
41. Gagnepain P, Henson R, Chetelat G, Desgranges B, Lebreton K, Eustache F. 2011. Is neocortical-hippocampal connectivity a better predictor of subsequent recollection than local increases in hippocampal activity? New insights on the role of priming. J Cogn Neurosci. 23:391-403.
42. Garrido MI, Kilner JM, Kiebel SJ, Friston KJ. 2007. Evoked brain responses are generated by feedback loops. Proc Natl Acad Sci USA. 104:20961-20966.
43. Garrido MI, Kilner JM, Kiebel SJ, Friston KJ. 2009. Dynamic causal modeling of the response to frequency deviants. J Neurophysiol. 101:2620-2631.
44. Garrido MI, Kilner JM, Kiebel SJ, Stephan KE, Baldeweg T, Friston KJ. 2009. Repetition suppression and plasticity in the human brain. Neuroimage. 48:269-279.
45. Garrido MI, Kilner JM, Kiebel SJ, Stephan KE, Friston KJ. 2007. Dynamic causal modelling of evoked potentials: a reproducibility study. Neuroimage. 36:571-580.
46. Giovagnoli AR, Erbetta A, Villani F, Avanzini G. 2005. Semantic memory in partial epilepsy: verbal and non-verbal deficits and neuroanatom-ical relationships. Neuropsychologia. 43:1482-1492.
47. Grady CL, Furey ML, Pietrini P, Horwitz B, Rapoport SI. 2001. Altered brain functional connectivity and impaired short-term memory in Alzheimer's disease. Brain. 124:739-756.
48. Grady CL, McIntosh AR, Craik FI. 2003. Age-related differences in the functional connectivity of the hippocampus during memory encoding. Hippocampus. 13:572-586.
49. Gualtieri CT, Johnson LG. 2006. Comparative neurocognitive effects of 5 psychotropic anticonvulsants and lithium. MedGenMed. 8:46.
50. Guye M, Bartolomei F, Ranjeva JP. 2008. Imaging structural and functional connectivity: towards a unified definition of human brain organization? Curr Opin Neurol. 21:393-403.
51. Hashimoto R, Lee K, Preus A, McCarley RW, Wible CG. 2010. An fMRI study of functional abnormalities in the verbal working memory system and the relationship to clinical symptoms in chronic schizophrenia. Cereb Cortex. 20:46-60.
52. Heim S, Eickhoff SB, Ischebeck AK, Friederici AD, Stephan KE, Amunts K. 2009. Effective connectivity of the left BA 44, BA 45, and inferior temporal gyrus during lexical and phonological decisions identified with DCM. Hum Brain Mapp. 30:392-402.
53. Hermann B, Meador KJ, Gaillard WD, Cramer JA. 2010. Cognition across the lifespan: antiepileptic drugs, epilepsy, or both? Epilepsy Behav. 17:1-5.
54. Higuchi S, Miyashita Y. 1996. Formation of mnemonic neuronal responses to visual paired associates in inferotemporal cortex is impaired by perirhinal and entorhinal lesions. Proc Natl Acad Sci USA. 93:739-743.
55. Hoffman P, Jefferies E, Ehsan S, Hopper S, Ralph MA. 2009. Selective short-term memory deficits arise from impaired domain-general semantic control mechanisms. J Exp Psychol Learn Mem Cogn. 35:137-156.
56. Kapur S, Craik FI, Tulving E, Wilson AA, Houle S, Brown GM. 1994. Neuroanatomical correlates of encoding in episodic memory: levels of processing effect. Proc Natl Acad Sci USA. 91:2008-2011.
57. Karlsgodt KH, Shirinyan D, van Erp TG, Cohen MS, Cannon TD. 2005. Hippocampal activations during encoding and retrieval in a verbal working memory paradigm. Neuroimage. 25:1224-1231.
58. Kiebel SJ, David O, Friston KJ. 2006. Dynamic causal modelling of evoked responses in EEG/MEG with lead field parameterization. Neuroimage. 30:1273-1284.
59. Kilner JM, Friston KJ. 2010. Topological inference for EEG and MEG data. Ann Appl Stat. 14:1272-1290.
60. Krauss GL, Summerfield M, Brandt J, Breiter S, Ruchkin D. 1997. Mesial temporal spikes interfere with working memory. Neurology. 49:975-980.
61. Lancelot C, Samson S, Ahad P, Baulac M. 2003. Effect of unilateral temporal lobe resection on short-term memory for auditory object and sound location. Ann N Y Acad Sci. 999:377-380.
62. Lee AC, Buckley MJ, Gaffan D, Emery T, Hodges JR, Graham KS. 2006. Differentiating the roles of the hippocampus and perirhinal cortex in processes beyond long-term declarative memory: a double dissociation in dementia. J Neurosci. 26:5198-5203.
63. Lepage M, Habib R, Cormier H, Houle S, McIntosh AR. 2000. Neural correlates of semantic associative encoding in episodic memory. Brain Res Cogn Brain Res. 9:271-280.
64. Liao W, Zhang Z, Pan Z, Mantini D, Ding J, Duan X, Luo C, Lu G, Chen H. 2010. Altered functional connectivity and small-world in mesial temporal lobe epilepsy. PLoS One. 5:e8525.
65. Maccotta L, Buckner RL, Gilliam FG, Ojemann GA. 2007. Changing frontal contributions to memory before and after medial temporal lobectomy. Cereb Cortex. 17:443-456.
66. Mainy N, Kahane P, Minotti L, Hoffmann D, Bertrand O, Lachaux JP. 2007. Neural correlates of consolidation in working memory. Hum Brain Mapp. 28:183-193.
67. Mattout J, Henson RN, Friston KJ. 2007. Canonical source reconstruction for MEG. Comput Intell Neurosci. 67613.
68. Meador KJ. 2006. Cognitive and memory effects of the new antiepileptic drugs. Epilepsy Res. 68:63-67.
69. Meador KJ, Gevins A, Loring DW, McEvoy LK, Ray PG, Smith ME, Motamedi GK, Evans BM, Baum C. 2007. Neuropsychological and neurophysiologic effects of carbamazepine and levetiracetam. Neurology. 69:2076-2084.
70. Mechelli A, Allen P, Amaro E, Jr., Fu CH, Williams SC, Brammer MJ, Johns LC, McGuire PK. 2007. Misattribution of speech and impaired connectivity in patients with auditory verbal hallucinations. Hum Brain Mapp. 28:1213-1222.
71. Mueller SG, Laxer KD, Scanlon C, Garcia P, McMullen WJ, Loring DW, Meador KJ, Weiner MW. 2011. Different structural correlates for verbal memory impairment in temporal lobe epilepsy with and without mesial temporal lobe sclerosis. Hum Brain Mapp.
72. Nee DE, Jonides J. 2008. Neural correlates of access to short-term memory. Proc Natl Acad Sci USA. 105:14228-14233.
73. Noppeney U, Price CJ, Penny WD, Friston KJ. 2006. Two distinct neural mechanisms for category-selective responses. Cereb Cortex. 16:437-445.
74. Ojemann GA, Schoenfield-McNeill J, Corina D. 2009. The roles of human lateral temporal cortical neuronal activity in recent verbal memory encoding. Cereb Cortex. 19:197-205.
75. Oldfield RC. 1971. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 9:97-113.
76. Olson IR, Moore KS, Stark M, Chatterjee A. 2006. Visual working memory is impaired when the medial temporal lobe is damaged. J Cogn Neurosci. 18:1087-1097.
77. Owen AM, Morris RG, Sahakian BJ, Polkey CE, Robbins TW. 1996. Double dissociations of memory and executive functions in working memory tasks following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man. Brain. 119(Pt 5):1597-1615.
78. Oztekin I, Davachi L, McElree B. 2010. Are representations in working memory distinct from representations in long-term memory? Neural evidence in support of a single store. Psychol Sci. 21:1123-1133.
79. Park SP, Kwon SH. 2008. Cognitive effects of antiepileptic drugs. J Clin Neurol. 4:99-106.
80. Penny WD, Stephan KE, Daunizeau J, Rosa MJ, Friston KJ, Schofield TM, Leff AP. 2010. Comparing families of dynamic causal models. PLoS Comput Biol. 6:e1000709.
81. Penny WD, Stephan KE, Mechelli A, Friston KJ. 2004. Comparing dynamic causal models. Neuroimage. 22:1157-1172.
82. Pereira FR, Alessio A, Sercheli MS, Pedro T, Bilevicius E, Rondina JM, Ozelo HF, Castellano G, Covolan RJ, Damasceno BP, et al. 2010. Asymmetrical hippocampal connectivity in mesial temporal lobe epilepsy: evidence from resting state fMRI. BMC Neurosci. 11:66.
83. Petersson KM, Gisselgard J, Gretzer M, Ingvar M. 2006. Interaction between a verbal working memory network and the medial temporal lobe. Neuroimage. 33:1207-1217.
84. Piekema C, Fernandez G, Postma A, Hendriks MP, Wester AJ, Kessels RP. 2007. Spatial and non-spatial contextual working memory in patients with diencephalic or hippocampal dysfunction. Brain Res. 1172:103-109.
85. Powell HW, Guye M, Parker GJ, Symms MR, Boulby P, Koepp MJ, Barker GJ, Duncan JS. 2004. Noninvasive in vivo demonstration of the connections of the human parahippocampal gyrus. Neuroimage. 22:740-747.
86. Powell HW, Richardson MP, Symms MR, Boulby PA, Thompson PJ, Duncan JS, Koepp MJ. 2007. Reorganization of verbal and nonverbal memory in temporal lobe epilepsy due to unilateral hippocampal sclerosis. Epilepsia. 48:1512-1525.
87. Prevey ML, Delaney RC, Cramer JA, Cattanach L, Collins JF, Mattson RH. 1996. Effect of valproate on cognitive functioning. Comparison with carbamazepine. The Department of Veterans Affairs Epilepsy Cooperative Study 264 Group. Arch Neurol. 53:1008-1016.
88. Price CJ, Warburton EA, Moore CJ, Frackowiak RS, Friston KJ. 2001. Dynamic diaschisis: anatomically remote and context-sensitive human brain lesions. J Cogn Neurosci. 13:419-429.
89. Rajah MN, McIntosh AR, Grady CL. 1999. Frontotemporal interactions in face encoding and recognition. Brain Res Cogn Brain Res. 8:259-269.
90. Ranganath C, D'Esposito M. 2001. Medial temporal lobe activity associated with active maintenance of novel information. Neuron. 31:865-873.
91. Ranganath C, D'Esposito M. 2005. Directing the mind's eye: prefrontal, inferior and medial temporal mechanisms for visual working memory. Curr Opin Neurobiol. 15:175-182.
92. Ranganath C, Heller A, Cohen MX, Brozinsky CJ, Rissman J. 2005. Functional connectivity with the hippocampus during successful memory formation. Hippocampus. 15:997-1005.
93. Reyt S, Picq C, Sinniger V, Clarencon D, Bonaz B, David O. 2010. Dynamic causal modelling and physiological confounds: a functional MRI study of vagus nerve stimulation. Neuroimage. 52:1456-1464.
94. Rissman J, Gazzaley A, D'Esposito M. 2008. Dynamic adjustments in prefrontal, hippocampal, and inferior temporal interactions with increasing visual working memory load. Cereb Cortex. 18:1618-1629.
95. Saling MM. 2009. Verbal memory in mesial temporal lobe epilepsy: beyond material specificity. Brain. 132:570-582.
96. Saling MM, Berkovic SF, O'Shea MF, Kalnins RM, Darby DG, Bladin PF. 1993. Lateralization of verbal memory and unilateral hippocampal sclerosis: evidence of task-specific effects. J Clin Exp Neuropsychol. 15:608-618.
97. Schilbach L, Koubeissi MZ, David N, Vogeley K, Ritzl EK. 2007. Being with virtual others: studying social cognition in temporal lobe epilepsy. Epilepsy Behav. 11:316-323.
98. Schon K, Quiroz YT, Hasselmo ME, Stern CE. 2009. Greater working memory load results in greater medial temporal activity at retrieval. Cereb Cortex. 19:2561-2571.
99. Seghier ML, Zeidman P, Neufeld NH, Leff AP, Price CJ. 2010. Identifying abnormal connectivity in patients using dynamic causal modeling of fMRI responses. Front Syst Neurosci. 4:142.
100. Seo JG, Lee DI, Hwang YH, Lee HW, Jung DK, Suh CK, Kwon SH, Park SP. 2007. Comparison of cognitive effects of lamotrigine and oxcarbazepine in epilepsy patients. J Clin Neurol. 3:31-37.
101. Simons JS, Spiers HJ. 2003. Prefrontal and medial temporal lobe interactions in long-term memory. Nat Rev Neurosci. 4:637-648.
102. Squire LR. 1991. The medial temporal lobe memory system. Science. 253:1380-1386.
103. Stephan KE, Friston KJ. 2007. Models of effective connectivity in neural systems. In: Jirsa VK, McIntosh AR, editors. Handbook of brain connectivity. Berlin (Germany): Springer-Verlag. p. 303-326.
104. Stephan KE, Penny WD, Daunizeau J, Moran RJ, Friston KJ. 2009. Bayesian model selection for group studies. Neuroimage. 46:1004-1017.
105. Sun W, Wang W, Wu X, Wang Y. 2007. Antiepileptic drugs and the significance of event-related potentials. J Clin Neurophysiol. 24:271-276.
106. Thom M, Zhou J, Martinian L, Sisodiya S. 2005. Quantitative postmortem study of the hippocampus in chronic epilepsy: seizures do not inevitably cause neuronal loss. Brain. 128:1344-1357.
107. Thompson PJ, Baxendale SA, Duncan JS, Sander JW. 2000. Effects of topiramate on cognitive function. J Neurol Neurosurg Psychiatry. 69:636-641.
108. Trenerry MR, Jack CR, Jr Ivnik RJ, Sharbrough FW, Cascino GD, Hirschorn KA, Marsh WR, Kelly PJ, Meyer FB. 1993. MRI hippocampal volumes and memory function before and after temporal lobectomy. Neurology. 43:1800-1805.
109. Tuunainen A, Nousiainen U, Pilke A, Mervaala E, Riekkinen P. 1995. Lateralization of event-related potentials during discontinuation of antiepileptic medication. Epilepsia. 36:262-269.
110. Van Dellen E, Douw L, Baayen JC, Heimans JJ, Ponten SC, Vandertop WP, Velis DN, Stam CJ, Reijneveld JC. 2009. Long-term effects of temporal lobe epilepsy on local neural networks: a graph theoretical analysis of corticography recordings. PLoS One. 4:e8081.
111. Vlooswijk MC, Jansen JF, Reijs RP, de Krom MC, Kooi ME, Majoie HJ, Hofman PA, Backes WH, Aldenkamp AP. 2008. Cognitive fMRI and neuropsychological assessment in patients with secondarily generalized seizures. Clin Neurol Neurosurg. 110:441-450.
112. Voets NL, Adcock JE, Stacey R, Hart Y, Carpenter K, Matthews PM, Beckmann CF. 2009. Functional and structural changes in the memory network associated with left temporal lobe epilepsy. Hum Brain Mapp. 30:4070-4081.
113. Wagner DD, Sziklas V, Garver KE, Jones-Gotman M. 2009. Material-specific lateralization of working memory in the medial temporal lobe. Neuropsychologia. 47:112-122.
114. Wagner K, Frings L, Halsband U, Everts R, Buller A, Spreer J, Zentner J, Schulze-Bonhage A. 2007. Hippocampal functional connectivity reflects verbal episodic memory network integrity. Neuroreport. 18:1719-1723.
115. Werner S, Noppeney U. 2010. Distinct functional contributions of primary sensory and association areas to audiovisual integration in object categorization. J Neurosci. 30:2662-2675.
116. Woloszyn L, Sheinberg DL. 2009. Neural dynamics in inferior temporal cortex during a visual working memory task. J Neurosci. 29:5494-5507.
117. Yogarajah M, Powell HW, Parker GJ, Alexander DC, Thompson PJ, Symms MR, Boulby P, Wheeler-Kingshott CA, Barker GJ, Koepp MJ, et al. 2008. Tractography of the parahippocampal gyrus and material specific memory impairment in unilateral temporal lobe epilepsy. Neuroimage. 40:1755-1764.
118. Zaveri HP, Pincus SM, GoncharovaII II, Novotny EJ, Duckrow RB, Spencer DD, Blumenfeld H, Spencer SS. 2010. Background in-tracranial EEG spectral changes with anti-epileptic drug taper. Clin Neurophysiol. 121:311-317.