Effects of perfluorooctanoic acid (PFOA) on expression of peroxisome proliferator-activated receptors (PPAR) and nuclear receptor-regulated genes in fetal and postnatal CD-1 mouse tissues

Reproductive Toxicology

Volumn 33, Issue 4, 2012, Pages 491-505

  Abbott, Barbara D ^a   Wood, Carmen R ^a   Watkins, Andrew M ^a   Tatum Gibbs, Katoria ^a   Das, Kaberi P ^a   Lau, Christopher ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Developmental toxicity; Perfluorooctanoic acid (PFOA); Peroxisome proliferator activated receptor alpha (PPAR ); Peroxisome proliferator activated receptor beta (PPAR ); Peroxisome proliferator activated receptor gamma (PPAR )

Indexed keywords

(NADP) DEPENDENT MALIC ENZYME 1; 3 HYDROXYACYL COENZYME A DEHYDROGENASE; ACYL COENZYME A OXIDASE; CARNITINE PALMITOYLTRANSFERASE I; CARNITINE PALMITOYLTRANSFERASE IB; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 2B10; CYTOCHROME P450 3A11; CYTOCHROME P450 4A14; ENOYL COENZYME A HYDRATASE; MALATE DEHYDROGENASE (NADP); MESSENGER RNA; PALMITOYL ACYL COENZYME A OXIDASE 1; PERFLUOROOCTANOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PREGNANE X RECEPTOR; PYRUVATE DEHYDROGENASE KINASE 4; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; DEVELOPMENTAL TOXICITY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; FATTY ACID OXIDATION; FEMALE; FETUS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GLUCOSE METABOLISM; LIVER LEVEL; METABOLIC REGULATION; MOUSE; NONHUMAN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA GENE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR BETA GENE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA GENE; POLYMERASE CHAIN REACTION; POSTNATAL DEVELOPMENT; PRENATAL DEVELOPMENT; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RECEPTOR GENE; TISSUE DISTRIBUTION; TOXICITY TESTING; WESTERN BLOTTING;

AGING; ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; ENVIRONMENTAL POLLUTANTS; FEMALE; FETAL DEVELOPMENT; FLUOROCARBONS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GESTATIONAL AGE; MALE; MICE; MICE, INBRED STRAINS; OCTANOIC ACIDS; ORGAN SPECIFICITY; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; REAL-TIME POLYMERASE CHAIN REACTION;

MUS;

EID: 84861528332     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2011.11.005     Document Type: Article

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