Reversibility of the reproductive toxicity of gossypol in peripubertal bulls

Theriogenology

Volumn 61, Issue 6, 2004, Pages 1171-1179

  Hassan, Magdy E ^a   Smith, Geof W ^b   Ott, Randall S ^a   Faulkner, Daniel B ^a   Firkins, Lawrence D ^a   Ehrhart, E J ^a   Schaeffer, David J ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Cottonseed meal; Gossypol; Reproductive toxicity

Indexed keywords

ANIMALIA; GLYCINE MAX; MICROPUS;

EID: 1242310818     PISSN: 0093691X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.theriogenology.2003.07.007     Document Type: Article

References (21)

1. Randel R.D., Chase C.C. Jr., Wyse S.J. Effect of gossypol and cottonseed products on reproduction of mammals. J. Anim. Sci. 70:1992;1628-1638.
2. Chenoweth P.J., Risco C.A., Larsen R.E., Velez J., Tran T., Chase C.C. Jr. Effect of dietary gossypol on aspects of semen quality, sperm morphology and sperm production in young Brahman bulls. Theriogenology. 2:1994;1-13.
3. Chase C.C. Jr., Bastidas P., Ruttle J.L., Long C.R., Randel R.D. Growth and reproductive development in Brahman bulls fed diets containing gossypol. J. Anim. Sci. 72:1994;445-452.
4. Arshami J., Ruttle J.L. Effects of diets containing gossypol on spermatogenic tissues of young bulls. Theriogenology. 30:1988;507-516.
5. Hoffer A.P., Lisser S.P. Recovery of normal testicular ultrastructure and sperm motility after cessation of gossypol treatment in rats. J. Androl. 5:1984;416-423.
6. Hancock J.L. The morphology of boar spermatozoa. J. R. Micro. Soc. 76:1957;84-97.
7. Ott RS. Breeding soundness examination of bulls. In: Morrow DA, editor. Current Therapy in Theriogenology, 2nd ed. Philadelphia: WB Saunders; 1986. p. 125-36.
8. Lagerlof N. The history of cytological and histological examination of sperm and testes. Communication of Veterinary College of State University of Ghent; 1966.
9. Barth AD, Oko RJ. Abnormal morphology of bovine spermatozoa. Ames: Iowa State University Press; 1989.
10. Veeramachaneni D.N.R., Ott R.S., Heath E.M., McEntee K., Bolt D.J., Hixon J.E. Pathophysiology of small testes in beef bulls: relationship between scrotal circumference, histopathologic features of testes and epididymides, seminal characteristics, and endocrine profiles. Am. J. Vet. Res. 47:1986;1988-1999.
11. Velasquez-Pereira J., Chenoweth P.J., McDowell L.R., Risco C.A., Staples C.A., Prichard D.et al. Reproductive effects of feeding gossypol and vitamin E to bulls. J. Anim. Sci. 76:1998;2894-2904.
12. Cusack P.M.V., Perry V. The effect of feeding whole cottonseed on fertility of bulls. Aust. Vet. J. 72:1995;463-470.
13. Abdel-Raouf M. Sexual behavior and semen picture of bulls of the Swedish Red and White breed between the ages of 9 and 15 months. Nord. Vet. Med. 17:1965;318-322.
14. Johnson K.R., Dewey C.E., Bobo J.K., Kelling C.L., Lunstra D.D. Prevalence of morphologic defects in spermatozoa from beef bulls. J. Am. Vet. Med. Assoc. 213:1998;1468-1471.
15. Madrid N., Ott R.S., Veeramachaneni R.D.N., Parrett D.F., Vanderwert W., Willms C.L. Scrotal circumference, seminal characteristics, and testicular lesions of yearling Angus bulls. Am. J. Vet. Res. 49:1988;579-585.
16. Jimenez D.A., Chandler J.E., Adkinson R.W., Nipper W.A., Baham A., Saxton A.M. Effect of feeding gossypol in cottonseed meal on growth, semen quality, and spermatogenesis of yearling Holstein bulls. J. Dairy Sci. 72:1989;866-1875.
17. Calhoun MC, Kuhlmann SW, Baldwin Jr BC. Assessing the gossypol status of cattle fed cotton feed products. Proc Pacific Northwest Anim Nutr Conf 1995:1-12.
18. Waller D.P., Bunyapraphatsara N., Martin A., Vournazos C.J., Ahmed M.S., Soejarto D.D.et al. Effect of (+)-gossypol on fertility in male hamsters. J. Androl. 4:1983;276-279.
19. Hoffer A.P., Agarwal A., Meltzer P., Herlihy P., Naqvi R.H., Lindberg M.C.et al. Ultrastructural, fertility, and spermicidal studies with isomers and derivatives of gossypol in male hamsters. Biol. Reprod. 37:1987;909-924.
20. Rogers G.M., Poore M.H. Optimal feeding management of gossypol-containing diets for beef cattle. Vet. Med. 90:1995;995-1002.
21. Smally S.A., Bicknell E.J. Gossypol toxicity in dairy cattle. Comp. Contin. Educ. Pract. Vet. 4:1982;378-381.