Hypoxia augments oscillatory blood flow in brachial artery during leg cycling

Medicine and Science in Sports and Exercise

Volumn 44, Issue 6, 2012, Pages 1035-1042

  Iwamoto, Erika ^a   Katayama, Keisho ^b   Oshida, Yoshiharu ^b   Ishida, Koji ^b  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

Aerobic exercise; blood flow pattern; dynamic leg exercise; hypoxia

Indexed keywords

ADULT; ANALYSIS OF VARIANCE; ANOXIA; ARTICLE; BLOOD FLOW VELOCITY; BRACHIAL ARTERY; ECHOGRAPHY; ELECTROCARDIOGRAPHY; ELECTROMYOGRAPHY; EXERCISE TEST; HUMAN; LEG; MALE; NONPARAMETRIC TEST; OXIMETRY; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PHYSIOLOGY; REPRODUCIBILITY; VASCULARIZATION;

ANALYSIS OF VARIANCE; ANOXIA; BLOOD FLOW VELOCITY; BRACHIAL ARTERY; ELECTROCARDIOGRAPHY; ELECTROMYOGRAPHY; EXERCISE TEST; HUMANS; LEG; MALE; OXIMETRY; OXYGEN CONSUMPTION; REPRODUCIBILITY OF RESULTS; STATISTICS, NONPARAMETRIC; YOUNG ADULT;

EID: 84861516160     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/MSS.0b013e31824294f9     Document Type: Article

References (45)

1. Bailey DM, Davies B, Baker J. Training in hypoxia: modulation of metabolic and cardiovascular risk factors in men. Med Sci Sports Exerc. 2000;32(6):1058-66.
2. Blackshear WM Jr, Phillips DJ, Strandness DE Jr. Pulsed Doppler assessment of normal human femoral artery velocity patterns. J Surg Res. 1979;27(2):73-83.
3. Buss DD, Bisgard GE. Myocardial function during acute hypoxia in the calf. Basic Res Cardiol. 1976;71(5):456-68.
4. Casey DP, Madery BD, Pike TL, et al. Adenosine receptor antagonist and augmented vasodilation during hypoxic exercise. J Appl Physiol. 2009;107(4):1128-37.
5. DeSouza CA, Shapiro LF, Clevenger CM, et al. Regular aerobic exercise prevents and restores age-related declines in endotheliumdependent vasodilation in healthy men. Circulation. 2000;102(12): 1351-7.
6. Green D, Cheetham C, Mavaddat L, et al. Effect of lower limb exercise on forearm vascular function: contribution of nitric oxide. Am J Physiol Heart Circ Physiol. 2002;283(3):H899-H907.
7. Green D, Cheetham C, Reed C, Dembo L, O'Driscoll G. Assessment of brachial artery blood flow across the cardiac cycle: retrograde flows during cycle ergometry. J Appl Physiol. 2002;93(1): 361-8.
8. Green DJ, Bilsborough W, Naylor LH, et al. Comparison of forearm blood flow responses to incremental handgrip and cycle ergometer exercise: relative contribution of nitric oxide. J Physiol. 2005; 562(Pt 2):617-28.
9. Green DJ, Maiorana A, O'Driscoll G, Taylor R. Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol. 2004;561(Pt 1):1-25.
10. Green DJ, Maiorana AJ, Cable NT. Point: exercise training does induce vascular adaptations beyond the active muscle beds. J Appl Physiol. 2008;105(3):1002-4.
11. Green DJ, Spence A, Halliwill JR, Cable NT, Thijssen DH. Exercise and vascular adaptation in asymptomatic humans. Exp Physiol. 2011;96(2):57-70.
12. Halliwill JR, Minson CT. Retrograde shear: backwards into the future? Am J Physiol Heart Circ Physiol. 2010;298(4):H1126-7.
13. Higashi Y, Sasaki S, Kurisu S, et al. Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects: role of endotheliumderived nitric oxide. Circulation. 1999;100(11):1194-202.
14. Hogan MC, Richardson RS, Haseler LJ. Human muscle performance and PCr hydrolysis with varied inspired oxygen fractions: a 31P-MRS study. J Appl Physiol. 1999;86(4):1367-73.
15. Johnson JM, Park MK. Effect of upright exercise on threshold for cutaneous vasodilation and sweating. J Appl Physiol. 1981; 50(4):814-8.
16. Kagaya A, Yoshizawa M, Maeda S, Tanaka H. Comments on point: counterpoint: exercise training does/does not induce vascular adaptations beyond the active muscle beds. J Appl Physiol. 2008;105(3):1009-10.
17. Katayama K, Amann M, Pegelow DF, Jacques AJ, Dempsey JA. Effect of arterial oxygenation on quadriceps fatigability during isolated muscle exercise. Am J Physiol Regul Integr Comp Physiol. 2007;292(3):R1279-86.
18. Katayama K, Ishida K, Iwamoto E, Iemitsu M, Koike T, Saito M. Hypoxia augments muscle sympathetic neural response to leg cycling. Am J Physiol Regul Integr Comp Physiol. 2011;301(2): R456-64.
19. Katayama K, Sato K, Akima H, et al. Ventilatory and cardiovascular responses to hypercapnia after 20 days of head-down bed rest. Aviat Space Environ Med. 2004;75(4):312-6.
20. Katayama K, Sato K, Hotta N, Ishida K, Iwasaki K, Miyamura M. Intermittent hypoxia does not increase exercise ventilation at simulated moderate altitude. Int J Sports Med. 2007;28(6):480-7.
21. Linke A, Schoene N, Gielen S, et al. Endothelial dysfunction in patients with chronic heart failure: systemic effects of lower-limb exercise training. J Am Coll Cardiol. 2001;37(2):392-7.
22. Mair J, Hammerer-Lercher A, Mittermayr M, et al. 3-week hiking holidays at moderate altitude do not impair cardiac function in individuals with metabolic syndrome. Int J Cardiol. 2008; 123(2):186-8.
23. Mazzeo RS. Physiological responses to exercise at altitude: an update. Sports Med. 2008;38(1):1-8.
24. McDonald DA. The relation of pulsatile pressure to flow in arteries. J Physiol. 1955;127(3):533-52.
25. Moran D, Epstein Y, Keren G, Laor A, Sherez J, Shapiro Y. Calculation of mean arterial pressure during exercise as a function of heart rate. Appl Human Sci. 1995;14(6):293-5.
26. Nishiwaki M, Kawakami R, Saito K, Tamaki H, Takekura H, Ogita F. Vascular adaptations to hypobaric hypoxic training in postmenopausal women. J Physiol Sci. 2011;61(2):83-91.
27. Ooue A, Ichinose TK, Inoue Y, Nishiyasu T, Koga S, Kondo N. Changes in blood flow in conduit artery and veins of the upper arm during leg exercise in humans. Eur J Appl Physiol. 2008; 103(3):367-73.
28. Padilla J, Young CN, Simmons GH, et al. Increased muscle sympathetic nerve activity acutely alters conduit artery shear rate patterns. Am J Physiol Heart Circ Physiol. 2010;298(4):H1128-35.
29. Razminia M, Trivedi A, Molnar J, et al. Validation of a new formula for mean arterial pressure calculation: the new formula is superior to the standard formula. Catheter Cardiovasc Interv. 2004;63(4):419-25.
30. Rowell LB. Human cardiovascular adjustments to exercise and thermal stress. Physiol Rev. 1974;54(1):75-159.
31. Saito M, Abe H, Iwase S, Koga K, Mano T. Muscle sympathetic nerve responsiveness to static contraction is not altered under hypoxia. Jpn J Physiol. 1991;41(5):775-83.
32. Saito M, Sone R, Ikeda M, Mano T. Sympathetic outflow to the skeletal muscle in humans increases during prolonged light exercise. J Appl Physiol. 1997;82(4):1237-43.
33. Saito M, Tsukanaka A, Yanagihara D, Mano T. Muscle sympathetic nerve responses to graded leg cycling. J Appl Physiol. 1993;75(2):663-7.
34. Schobersberger W, Schmid P, Lechleitner M, et al. Austrian Moderate Altitude Study 2000 (AMAS 2000). The effects of moderate altitude (1,700 m) on cardiovascular and metabolic variables in patients with metabolic syndrome. Eur J Appl Physiol. 2003;88(6):506-14.
35. Seals DR, Johnson DG, Fregosi RF. Hypoxia potentiates exerciseinduced sympathetic neural activation in humans. J Appl Physiol. 1991;71(3):1032-40.
36. Shiroishi K, Kime R, Osada T, Murase N, Shimomura K, Katsumura T. Decreased muscle oxygenation and increased arterial blood flow in the non-exercising limb during leg exercise. Adv Exp Med Biol. 2010;662:379-84.
37. Simmons GH, Padilla J, Young CN, et al. Increased brachial artery retrograde shear rate at exercise onset is abolished during prolonged cycling: role of thermoregulatory vasodilation. J Appl Physiol. 2011;110(2):389-97.
38. Stenberg J, Ekblom B, Messin R. Hemodynamic response to work at simulated altitude, 4,000 m. J Appl Physiol. 1966;21(5):1589-94.
39. Tanaka H, Bassett DR Jr, Turner MJ. Exaggerated blood pressure response to maximal exercise in endurance-trained individuals. Am J Hypertens. 1996;9(11):1099-103.
40. Tanaka H, Shimizu S, Ohmori F, et al. Increases in blood flow and shear stress to nonworking limbs during incremental exercise. Med Sci Sports Exerc. 2006;38(1):81-5.
41. Thijssen DH, Dawson EA, Tinken TM, Cable NT, Green DJ. Retrograde flow and shear rate acutely impair endothelial function in humans. Hypertension. 2009;53(6):986-92.
42. Tinken TM, Thijssen DH, Hopkins N, et al. Impact of shear rate modulation on vascular function in humans. Hypertension. 2009;54(2):278-85.
43. Tinken TM, Thijssen DH, Hopkins N, Dawson EA, Cable NT, Green DJ. Shear stress mediates endothelial adaptations to exercise training in humans. Hypertension. 2010;55(2):312-8.
44. Wiles PG, Grant PJ, Jones RG, Knibbs AV, Hampton IF. Lowered skin blood flow at exhaustion. Lancet. 1986;2(8501):295.
45. Yoshizawa M, Shimizu-Okuyama S, Kagaya A. Transient increase in femoral arterial blood flow to the contralateral non-exercising limb during one-legged exercise. Eur J Appl Physiol. 2008;103(5):509-14.