Pulsatile atheroprone shear stress affects the expression of transient receptor potential channels in human endothelial cells

Hypertension

Volumn 59, Issue 6, 2012, Pages 1232-1240

  Thilo, Florian ^a   Vorderwülbecke, Bernd J ^a   Marki, Alex ^a   Krueger, Katharina ^a   Liu, Ying ^b,c   Baumunk, Daniel ^d   Zakrzewicz, Andreas ^a   Tepel, Martin ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

^c TONGJI UNIVERSITY   (China)

^d OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Endothelial cells; mRNA expression; Shear stress; TRP channels

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 4; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7; TUMOR NECROSIS FACTOR ALPHA; VANILLOID RECEPTOR 1;

ADULT; ARTICLE; ATHEROSCLEROSIS; BINDING SITE; CONTROLLED STUDY; FEMALE; FLOW KINETICS; GENE EXPRESSION REGULATION; GENE INDUCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PULSATILE ATHEROPRONE SHEAR STRESS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHEAR STRESS; TRANSCRIPTION INITIATION; UMBILICAL VEIN ENDOTHELIAL CELL;

ARTERIES; ATHEROSCLEROSIS; BASE SEQUENCE; BINDING SITES; BLOTTING, WESTERN; CELLS, CULTURED; FEMALE; GATA1 TRANSCRIPTION FACTOR; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; PULSATILE FLOW; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STRESS, MECHANICAL; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRPC CATION CHANNELS; TRPM CATION CHANNELS; TRPV CATION CHANNELS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84861511471     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.183608     Document Type: Article

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