Shear stress increases endothelial hyaluronan synthase 2 and hyaluronan synthesis especially in regard to an atheroprotective flow profile

Experimental Physiology

Volumn 96, Issue 9, 2011, Pages 977-986

  Maroski, Julian ^a   Vorderwülbecke, Bernd J ^a   Fiedorowicz, Katarzyna ^a   Da Silva Azevedo, Luis ^a   Siegel, Günter ^a,b   Marki, Alex ^a   Pries, Axel Radlach ^a,c   Zakrzewicz, Andreas ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UPPSALA UNIVERSITY   (Sweden)

^c DEUTSCHES HERZZENTRUM BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HYALURONAN SYNTHASE 2; HYALURONIC ACID DERIVATIVE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ARTERY BLOOD FLOW; ARTICLE; ATHEROSCLEROSIS; CELL CULTURE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART PROTECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PULSATILE FLOW; REAL TIME POLYMERASE CHAIN REACTION; SHEAR STRESS; SIGNAL TRANSDUCTION; SYNTHESIS; UMBILICAL VEIN ENDOTHELIAL CELL;

EID: 80051944499     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2010.056051     Document Type: Article

References (34)

1. Allison DD & Grande-Allen KJ (2006). Hyaluronan: a powerful tissue engineering tool. Tissue Eng 12, 2131-2140.
2. Bongrazio M, Baumann C, Zakrzewicz A, Pries AR & Gaehtgens P (2000). Evidence for modulation of genes involved in vascular adaptation by prolonged exposure of endothelial cells to shear stress. Cardiovasc Res 47, 384-393.
3. Bongrazio M, Da Silva-Azevedo L, Bergmann EC, Baum O, Hinz B, Pries AR & Zakrzewicz A (2006). Shear stress modulates the expression of thrombospondin-1 and CD36 in endothelial cells in vitro and during shear stress-induced angiogenesis in vivo. Int J Immunopathol Pharmacol 19, 35-48.
4. Braddock M, Schwachtgen JL, Houston P, Dickson MC, Lee MJ & Campbell CJ (1998). Fluid shear stress modulation of gene expression in endothelial cells. News Physiol Sci 13, 241-246.
5. Chatzisis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL & Stone PH (2007). Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling. J Am Coll Cardiol 49, 2379-2393.
6. Chlench S, Mecha Disassa N, Hohberg M, Hoffmann C, Pohlkamp T, Beyer G, Bongrazio M, Da Silva-Azevedo L, Baum O, Pries AR & Zakrzewicz A (2007). Regulation of Foxo-1 and the angiopoetin-2/Tie-2 system by shear stress. FEBS Lett 581, 673-680.
7. Dai G, Kaazempur-Mofrad MR, Natarajan S, Zhang Y, Vaughn S, Blackman BR, Kamm RD, García-Cardeña G & Gimbrone MA (2004). Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature. Proc Natl Acad Sci USA 101, 14871-14876.
8. Davies PF (1995). Flow-mediated endothelial mechanotransduction. Physiol Rev 76, 519-560.
9. Davies PF & Tripathi SC (1993). Mechanical stress mechanisms and the cell. An endothelial paradigm. Circ Res 72, 239-245.
10. Dimmeler S, Assmus B, Hermann C, Haendeler J & Zeiher AM (1998). Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis. Circ Res 83, 334-341.
11. Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F, Luft FC, Schedl A, Haller H & Kurzchalia TV (2001). Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science 293, 2449-2452.
12. Gouverneur M, Spaan JA, Pannekoek H, Fontijn RD & Vink H (2006a). Fluid shear stress stimulates incorporation of hyaluronan into endothelial cell glycocalyx. Am J Physiol Heart Circ Physiol 290, 458-462.
13. Gouverneur M, Van Den Berg BM, Nieuwdorp M, Stroes E & Vink H (2006b). Vasculoprotective properties of the endothelial glycocalyx: effects of fluid shear stress. J Intern Med 259, 393-400.
14. Hohberg M, Knöchel J, Hoffmann CJ, Chlench S, Wunderlich W, Alter A, Maroski J, Vorderwülbecke BJ, Silva-Azevedo LD, Knudsen R, Lehmann R, Fiedorowicz K, Bongrazio M, Nitsche B, Hoepfner M, Styp-Rekowska B, Pries AR & Zakrzewicz A (2011). Expression ofADAMTS1 in endothelial cells is induced by shear stress and suppressed in sprouting capillaries. J Cell Physiol 226, 350-61.
15. Hsieh HJ, Li NQ & Frangos JA (1991). Shear stress increases endothelial platelet derived growth factor mRNA levels. Am J Physiol Heart Circ Physiol 260, H642-H646.
16. Itano N, Sawai T, Yoshida M, Lenas P, Yamada Y, Imagawa M, Shinomura T, Hamaguchi M, Yoshida Y, Ohnuki Y, Miyauchi S, Spicer AP, McDonald JA & Kimata K (1999). Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. J Biol Chem 274, 25085-25092.
17. King J & Laemmli UK (1971). Polypeptides of the tail fibres of bacteriophage T4. J Mol Biol 62, 465-477.
18. Langille BL (1993). Remodeling of developing and mature arteries: endothelium, smooth muscle and matrix. J Cardiovasc Pharmacol 21(Suppl 1), 11-17.
19. 1-integrin in the activation of PI3-kinase-Akt by flow (shear stress) in resistance arteries. Am J Physiol Heart Circ Physiol 294, H1906-H1913.
20. Mochizuki S, Vink H, Hiramatsu O, Kajita T, Shigeto F, Spaan JA & Kajiya F (2003). Role of hyaluronic acid glycosaminoglycans in shear-induced endothelium-derived nitric oxide release. Am J Physiol Heart Circ Physiol 285, H722-H726.
21. Nieuwdorp M, Holleman F, de Groot E, Vink H, Gort J, Kontush A, Chapman MJ, Hutten BA, Brouwer CB, Hoekstra JB, Kastelein JJ & Stroes ES (2007). Perturbation of hyaluronan metabolism predisposes patients with type 1 diabetes mellitus to atherosclerosis. Diabetologica 50, 1288-1293.
22. Noble MI, Drake-Holland AJ & Vink H (2008). Hypothesis: arterial glycocalyx dysfunction is the first step in the atherothrombotic process. QJM 101, 513-518.
23. Pahakis MY, Kosky JR, Dull RO & Tarbell JM (2007). The role of endothelial glycocalyx components in mechanotransduction of fluid shear stress. Biochem Biophys Res Commun 355, 228-233.
24. Pries AR, Secomb TW & Gaehtgens P (1995). Design principles of vascular beds. Circ Res 77, 1017-1023.
25. Pries AR, Secomb TW & Gaehtgens P (2000). The endothelial surface layer. Pflugers Arch 440, 653-666.
26. Reitsma S, Slaaf DW & Vink H (2007). The endothelial glycocalyx: composition, functions and visualization. Pflugers Arch 454, 345-359.
27. Suzuki K, Yamamoto T, Usui T, Suzuki K, Heldin P & Yamashita H (2003). Expression of hyaluronan synthase in intraocular proliferative disease: regulation of expression in human vascular endothelial cells by transforming growth factor-β. Jpn J Ophthalmol 47, 557-564.
28. Tarbell JM & Pahakis MY (2006). Mechanotransduction and the glycocalyx. J Intern Med 259, 339-350.
29. Traub O & Berk BC (1998). Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vasc Biol 18, 677-685.
30. van den Berg BM, Spaan JA, Rolf TM & Vink H (2006). Atherogenic region and diet diminish glycocalyx dimension and increase intima-to-media ratios at murine carotid artery bifurcations. Am J Physiol Heart Circ Physiol 290, H915-H920.
31. van den Berg BM, Vink H & Spaan JA (2003). The endothelial glycocalyx protects against myocardial edema. Circ Res 92, 592-594.
32. Weinbaum S, Tarbell JM & Damiano ER (2007). The structure and function of the endothelial glycocalyx layer. Annu Rev Biomed Eng 9, 121-167.
33. Woolf N (1982). The Arterial Endothelium. Pathology of Atherosclerosis. Butterworths, pp. 25-45. London, UK.
34. Yoshizumi M, Abe J, Tsuchiya K, Berk BC & Tamaki T (2003). Stress and vascular responses: atheroprotective effect of laminar fluid shear stress in endothelial cells: possible role of mitogen-activated protein kinases. J Pharmacol Sci 91, 172-176.