Requirement of Ca2+ influx- and phosphatidylinositol 3-kinase-mediated m-calpain activity for shear stress-induced endothelial cell polarity

American Journal of Physiology - Cell Physiology

Volumn 293, Issue 4, 2007, Pages

  Miyazaki, Takuro ^a   Honda, Kazuo ^a   Ohata, Hisayuki ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

Fluid flow; Focal adhesion reorganization; Mechanotransduction; Morphological change

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; CALPAIN; CALPEPTIN; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GADOLINIUM; M CALPAIN; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MU CALPAIN; NEOMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C INHIBITOR; PROTEIN KINASE B; SMALL INTERFERING RNA; TALIN; UNCLASSIFIED DRUG; VINCULIN; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ACTIN; CALCIUM; CALPAIN 2; CHROMONE DERIVATIVE; DIPEPTIDE; FLAVONOID; M-CALPAIN; MORPHOLINE DERIVATIVE; PROTEIN KINASE INHIBITOR;

ARTICLE; CALCIUM TRANSPORT; CELL POLARITY; CELL STRUCTURE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOSKELETON; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FOCAL ADHESION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; SHEAR STRENGTH; CELL CULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; MECHANICAL STRESS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PSEUDOPODIUM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; CALCIUM; CALPAIN; CELL POLARITY; CELLS, CULTURED; CHROMONES; CYTOSKELETON; DIPEPTIDES; ENDOTHELIAL CELLS; FLAVONOIDS; FOCAL ADHESIONS; GADOLINIUM; HUMANS; MICROSCOPY, CONFOCAL; MORPHOLINES; NEOMYCIN; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; PSEUDOPODIA; RNA, SMALL INTERFERING; STRESS, MECHANICAL; TALIN; VINCULIN;

EID: 35048900480     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00083.2007     Document Type: Article

References (39)

1. Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270: 27489-27494, 1995.
2. Ariyoshi H, Yoshikawa N, Aono Y, Tsuji Y, Ueda A, Tokunaga M, Sakon M, Monden M. Localized activation of m-calpain in migrating human umbilical vein endothelial cells stimulated by shear stress. J Cell Biochem 81: 184-192, 2001.
3. Beckerle MC, Burridge K, DeMartino GN, Croall DE. Colocalization of calcium-dependent protease II and one of its substrates at site of cell adhesion. Cell 51: 569-577, 1987.
4. Butcher JT, Penrod AM, Garcia AJ, Nerem RM. Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments. Arterioscler Thromb Vasc Biol 24: 1429-1434, 2004.
5. Coll JL, Ben-Ze'ev A, Ezzell RM, Rodriguez Fernandez JL, Baribault H, Oshima RG, Adamson ED. Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion. Proc Natl Acad Sci USA 92: 9161-9165, 1995.
6. FAK) cleavage and regulation by calpain. Biochem J 318: 41-47, 1996.
7. Cunningham KS, Gotlieb AI. The role of shear stress in the pathogenesis of atherosclerosis. Lab Invest 85: 9-23, 2005.
8. Davies PF. Flow-mediated endothelial mechanotransduction. Physiol Rev 75: 519-560, 1995.
9. Dimmeler S, Assmus B, Hermann C, Haendeler J, Zeiher AM. Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis. Circ Res 83: 334-341, 1998.
10. Du X, Saido TC, Tsubuki S, Indig FE, Williams MJ, Ginsberg MH. Calpain cleavage of the cytoplasmic domain of the integrin β3 subunit. J Biol Chem 270: 26146-26151, 1995.
11. Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA, Trzaskos JM. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273: 18623-18632, 1998.
12. Franco SJ, Rodgers MA, Perrin BJ, Han J, Bennin DA, Critchley DR, Huttenlocher A. Calpain-mediated proteolysis of talin regulates adhesion dynamics. Nat Cell Biol 6: 977-983, 2004.
13. Fujitani K, Kambayashi J, Sakon M, Ohmi SI, Kawashima S, Yukawa M, Yano Y, Miyoshi H, Ikeda M, Shinoki N, Monden M. Identification of μ-, m-calpains and calpastatin and capture of μ-calpain activation in endothelial cells. J Cell Biochem 66: 197-209, 1997.
14. 2). Biochim Biophys Acta 979: 105-112, 1989.
15. Go YM, Park H, Maland MC, Darley-Usmar VM, Stoyanov B, Wetzker R, Jo H. Phosphatidylinositol 3-kinase gamma mediates shear stress-dependent activation of JNK in endothelial cells. Am J Physiol Heart Circ Physiol 275: H1898-H1904, 1998.
16. Gitler D, Spira ME. Real time imaging of calcium-induced localized proteolytic activity after axotomy and its relation to growth cone formation. Neuron 20: 1123-1135, 1998.
17. Girard PR, Nerem RM. Shear stress modulates endothelial cell morphology and F-actin organization through the regulation of focal adhesion-associated proteins. J Cell Physiol 163: 179-193, 1995.
18. Glading A, Bodnar RJ, Reynolds IJ, Shiraha H, Satish L, Potter DA, Blair HC, Wells A. Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation. Mol Cell Biol 24: 2499-2512, 2004.
19. Glading A, Uberall F, Keyse SM, Lauffenburger DA, Wells A. Membrane proximal ERK signaling is required for m-calpain activation downstream of epidermal growth factor receptor signaling. J Biol Chem 276: 23341-23348, 2001.
20. Goll DE, Thompson VF, Li H, Wei W, Cong J. The calpain system. Physiol Rev 83: 731-801, 2003.
21. Hamill OP, McBride DW Jr. The pharmacology of mechanogated membrane ion channels. Pharmacol Rev 48: 231-252, 1996.
22. 2+ oscillations and STOC activation in endothelial cells. FASEB J 12: 359-366, 1998.
23. Ilic D, Furuta Y, Kanazawa S, Takeda N, Sobue K, Nakatsuji N, Nomura S, Fujimoto J, Okada M, Yamamoto T. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 377: 539-544, 1995.
24. Leytus SP, Patterson WL, Mangel WF. New class of sensitive and selective fluorogenic substrates for serine proteinases. Amino acid and dipeptide derivatives of rhodamine. Biochem J 215: 253-260, 1983.
25. Li S, Butler P, Wang Y, Hu Y, Han DC, Usami S, Guan JL, Chien S. The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells. Proc Natl Acad Sci USA 99: 3546-3551, 2002.
26. Li S, Huang NF, Hsu S. Mechanotransduction in endothelial cell migration. J Cell Biochem 96: 1110-1126, 2005.
27. Malek AM, Izumo S. Mechanism of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress. J Cell Sci 109: 713-726, 1996.
28. 2+ transients in retracted regions in vascular endothelial cells. Biochem Biophys Res Commun 281: 172-179, 2001.
29. Nollert MU, Eskin SG, McIntire LV. Shear stress increases inositol trisphosphate levels in human endothelial cells. Biochem Biophys Res Commun 170: 281-287, 1990.
30. Qiu K, Su Y, Block ER. Use of recombinant calpain-2 siRNA adenovirus to assess calpain-2 modulation of lung endothelial cell migration and proliferation. Mol Cell Biochem 292: 69-78, 2006.
31. Saido TC, Sorimachi H, Suzuki K. Calpain: new perspectives in molecular diversity and physiological-pathological involvement. FASEB J 8: 814-822, 1994.
32. Satish L, Blair HC, Glading A, Wells A. IP-9 (CXCL11) induced cell motility in keratinocytes requires calcium flux-dependent activation of μ-calpain. Mol Cell Biol 25: 1922-1941, 2005.
33. Serrano K, Devine DV. Vinculin is proteolyzed by calpain during platelet aggregation: 95 kDa cleavage fragment associates with the platelet cytoskeleton. Cell Motil Cytoskeleton 58: 242-252, 2004.
34. Shao H, Chou J, Baty CJ, Burke NA, Watkins SC, Stolz DB, Wells A. Spatial localization of m-calpain to the plasma membrane by phosphoinositide biphosphate binding during epidermal growth factor receptor-mediated activation. Mol Cell Biol 26: 5481-5496, 2006.
35. Turini P, Kurooka S, Steer M, Corbascio AN, Singer TP. The action of phenylmethylsulfonyl fluoride on human acetylcholinesterase, chymotrypsin and trypsin. J Pharmacol Exp Ther 167: 98-104, 1969.
36. Urbich C, Dernbach E, Reissner A, Vasa M, Zeiher AM, Dimmeler S. Shear stress-induced endothelial cell migration involves integrin signaling via the fibronectin receptor subunits α5 and β1. Arterioscler Thromb Vasc Biol 22: 69-75, 2002.
37. Viana F, de Smedt H, Droogmans G, Nilius B. Calcium signalling through nucleotide receptor P2Y2 in cultured human vascular endothelium. Cell Calcium 24: 117-127, 1998.
38. Yoshikawa N, Ariyoshi H, Ikeda M, Sakon M, Kawasaki T, Monden M. Shear-stress causes polarized change in cytoplasmic calcium concentration in human umbilical vein endothelial cells (HUVECs). Cell Calcium 22: 189-194, 1997.
39. 2+ oscillations in response to cholecystokinin and carbachol but not to JMV-180 in rat pancreatic acinar cells. J Biol Chem 267: 13830-13835, 1992.