메뉴 건너뛰기




Volumn 19, Issue 1, 2012, Pages 126-141

Selective adenosine agonists and myocardial perfusion imaging

Author keywords

Apadenoson; Binodenoson; Myocardial perfusion imaging; Regadenoson; Selective adenosine agonists

Indexed keywords

ADENOSINE; ADENOSINE A2 RECEPTOR; ADENOSINE A2 RECEPTOR AGONIST; AMINOPHYLLINE; APADENOSON; ATL 149E; BINODENOSON; CORVUE; INSULIN; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; PLACEBO; REGADENOSON; THALLIUM 201; UNCLASSIFIED DRUG; WATER O 15; ADENOSINE RECEPTOR STIMULATING AGENT; DIAGNOSTIC AGENT; VASODILATOR AGENT;

EID: 84861509861     PISSN: 10713581     EISSN: 15326551     Source Type: Journal    
DOI: 10.1007/s12350-011-9474-9     Document Type: Review
Times cited : (60)

References (41)
  • 1
    • 0030469845 scopus 로고    scopus 로고
    • Pharmacology of coronary vasodilation: A brief review
    • Orlandi C. Pharmacology of coronary vasodilation: A brief review. J Nucl Cardiol 1996;3:S27-30.
    • (1996) J Nucl Cardiol , vol.3
    • Orlandi, C.1
  • 2
    • 0035215838 scopus 로고    scopus 로고
    • The role of capillaries in determining coronary blood flow reserve: Implications for stress-induced reversible perfusion defects
    • DOI 10.1067/mnc.2001.119690
    • Kaul S. The role of capillaries in determining coronary blood flow reserve: Implications for stress-induced reversible perfusion defects. J Nucl Cardiol 2001;8:694-700. (Pubitemid 33150248)
    • (2001) Journal of Nuclear Cardiology , vol.8 , Issue.6 , pp. 694-700
    • Kaul, S.1
  • 3
    • 0037355677 scopus 로고    scopus 로고
    • Neue ansatze der magnetresonanztomographie zur beschreibung myokardialer mikrozirkulationsparameter am menschen
    • DOI 10.1007/s00059-003-2451-6
    • Wacker CM, Bauer WR. Myocardial microcirculation in humans - new approaches using MRI. Herz 2003;28:74-81. (Pubitemid 36406361)
    • (2003) Herz , vol.28 , Issue.2 , pp. 74-81
    • Wacker, C.M.1    Bauer, W.R.2
  • 4
    • 70049114599 scopus 로고    scopus 로고
    • Pharmacological stress testing
    • Garcia EV, Iskandrian AE, editors. New York: Oxford University Press
    • Zoghbi GJ, Iskandrian AE. Pharmacological stress testing. In: Garcia EV, Iskandrian AE, editors. Nuclear cardiac imaging: Principles and applications. New York: Oxford University Press; 2008. p. 293-315.
    • (2008) Nuclear Cardiac Imaging: Principles and Applications , pp. 293-315
    • Zoghbi, G.J.1    Iskandrian, A.E.2
  • 5
    • 77953326814 scopus 로고    scopus 로고
    • The emerging role of the selective A2A agonist in pharmacologic stress testing
    • Gemignani AS, Abbott BG. The emerging role of the selective A2A agonist in pharmacologic stress testing. J Nucl Cardiol 2010; 17:494-7.
    • (2010) J Nucl Cardiol , vol.17 , pp. 494-497
    • Gemignani, A.S.1    Abbott, B.G.2
  • 6
    • 0028946706 scopus 로고
    • Adenosine receptor subtypes: Characterization and therapeutic regulation
    • Olah ME, Stiles GL. Adenosine receptor subtypes: Characterization and therapeutic regulation. Annu Rev Pharmacol Toxicol 1995;35:581-606.
    • (1995) Annu Rev Pharmacol Toxicol , vol.35 , pp. 581-606
    • Olah, M.E.1    Stiles, G.L.2
  • 7
    • 0037368371 scopus 로고    scopus 로고
    • Pharmacologic stress testing: New methods and new agents
    • DOI 10.1067/mnc.2003.5
    • Hendel RC, Jamil T, Glover DK. Pharmacologic stress testing: New methods and new agents. J Nucl Cardiol 2003;10:197-204. (Pubitemid 36503806)
    • (2003) Journal of Nuclear Cardiology , vol.10 , Issue.2 , pp. 197-204
    • Hendel, R.C.1    Jamil, T.2    Glover, D.K.3
  • 9
    • 79952027612 scopus 로고    scopus 로고
    • Recent developments in adenosine receptor ligands and their potential as novel drugs
    • Muller CE, Jacobson KA. Recent developments in adenosine receptor ligands and their potential as novel drugs. Biochim Biophys Acta 2010;1808:1290-308.
    • (2010) Biochim Biophys Acta , vol.1808 , pp. 1290-1308
    • Muller, C.E.1    Jacobson, K.A.2
  • 10
    • 70049109278 scopus 로고    scopus 로고
    • Regadenoson: A new myocardial stress agent
    • Al Jaroudi W, Iskandrian AE. Regadenoson: A new myocardial stress agent. J Am Coll Cardiol 2009;54:1123-30.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1123-1130
    • Al Jaroudi, W.1    Iskandrian, A.E.2
  • 12
    • 33845445489 scopus 로고    scopus 로고
    • 2A-receptor agonist, in healthy male volunteers
    • DOI 10.2165/00003088-200645120-00005
    • Gordi T, Frohna P, Sun HL, Wolff A, Belardinelli L, Lieu H. A population pharmacokinetic/pharmacodynamic analysis of regadenoson, an adenosine A2A-receptor agonist, in healthy male volunteers. Clin Pharmacokinet 2006;45:1201-12. (Pubitemid 44904823)
    • (2006) Clinical Pharmacokinetics , vol.45 , Issue.12 , pp. 1201-1212
    • Gordi, T.1    Frohna, P.2    Sun, H.-L.3    Wolff, A.4    Belardinelli, L.5    Lieu, H.6
  • 13
    • 34548042995 scopus 로고    scopus 로고
    • Regadenoson pharmacokinetics and tolerability in subjects with impaired renal function
    • Gordi T, Blackburn B, Lieu H. Regadenoson pharmacokinetics and tolerability in subjects with impaired renal function. J Clin Pharmacol 2007;47:825-33.
    • (2007) J Clin Pharmacol , vol.47 , pp. 825-833
    • Gordi, T.1    Blackburn, B.2    Lieu, H.3
  • 14
    • 16244421094 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of binodenoson after intravenous dose escalation in healthy volunteers
    • DOI 10.1016/j.nuclcard.2004.12.294, PII S1071358104008207
    • Barrett RJ, Lamson MJ, Johnson J, Smith WB. Pharmacokinetics and safety of binodenoson after intravenous dose escalation in healthy volunteers. J Nucl Cardiol 2005;12:166-71. (Pubitemid 40450766)
    • (2005) Journal of Nuclear Cardiology , vol.12 , Issue.2 , pp. 166-171
    • Barrett, R.J.1    Lamson, M.J.2    Johnson, J.3    Smith, W.B.4
  • 17
    • 3142702719 scopus 로고    scopus 로고
    • The future of pharmacologic stress: Selective A2A adenosine receptor agonists
    • discussion 40D-42D
    • Cerqueira MD. The future of pharmacologic stress: Selective A2A adenosine receptor agonists. Am J Cardiol 2004;94:33D-40D. discussion 40D-42D.
    • (2004) Am J Cardiol , vol.94
    • Cerqueira, M.D.1
  • 18
    • 0037215393 scopus 로고    scopus 로고
    • 2a adenosine receptor agonist as a coronary vasodilator in conscious dogs: Potential for use in myocardial perfusion imaging
    • DOI 10.1097/00005344-200301000-00017
    • Trochu JN, Zhao G, Post H, Xu X, Belardinelli L, Belloni FL, et al. Selective A2A adenosine receptor agonist as a coronary vasodilator in conscious dogs: Potential for use in myocardial perfusion imaging. J Cardiovasc Pharmacol 2003;41:132-9. (Pubitemid 36015065)
    • (2003) Journal of Cardiovascular Pharmacology , vol.41 , Issue.1 , pp. 132-139
    • Trochu, J.-N.1    Zhao, G.2    Post, H.3    Xu, X.4    Belardinelli, L.5    Belloni, F.L.6    Hintze, T.H.7
  • 20
    • 70349775786 scopus 로고    scopus 로고
    • Effects of adenosine and a selective A2A adenosine receptor agonist on hemodynamic and thallium-201 and technetium-99m-sestaMIBI biodistribution and kinetics
    • Mekkaoui C, Jadbabaie F, Dione DP, Meoli DF, Purushothaman K, Belardinelli L, et al. Effects of adenosine and a selective A2A adenosine receptor agonist on hemodynamic and thallium-201 and technetium-99m-sestaMIBI biodistribution and kinetics. JACC Cardiovasc Imaging 2009;2:1198-208.
    • (2009) JACC Cardiovasc Imaging , vol.2 , pp. 1198-1208
    • Mekkaoui, C.1    Jadbabaie, F.2    Dione, D.P.3    Meoli, D.F.4    Purushothaman, K.5    Belardinelli, L.6
  • 21
    • 0029778320 scopus 로고    scopus 로고
    • Pharmacological stress thallium scintigraphy with 2- cyclohexylmethylidenehydrazinoadenosine (WRC-0470): A novel, short-acting adenosine A(2A) receptor agonist
    • GloverDK,RuizM,Yang JY,KoplanBA,AllenTR, SmithWH, et al. Pharmacological stress thallium scintigraphy with 2-cyclohexylmethylidenehydrazinoadenosine (WRC-0470). A novel, shortacting adenosineA2Areceptor agonist. Circulation 1996;94:1726-32. (Pubitemid 26320281)
    • (1996) Circulation , vol.94 , Issue.7 , pp. 1726-1732
    • Glover, D.K.1    Ruiz, M.2    Yang, J.Y.3    Koplan, B.A.4    Allen, T.R.5    Smith, W.H.6    Watson, D.D.7    Barrett, R.J.8    Beller, G.A.9
  • 23
    • 59449095471 scopus 로고    scopus 로고
    • Regadenoson, a novel pharmacologic stress agent for use in myocardial perfusion imaging, does not have a direct effect on the QT interval in conscious dogs
    • Zhao G, Serpllion S, Shryock J, Messina E, Xu X, Ochoa M, et al. Regadenoson, a novel pharmacologic stress agent for use in myocardial perfusion imaging, does not have a direct effect on the QT interval in conscious dogs. J Cardiovasc Pharmacol 2008;52:467-73.
    • (2008) J Cardiovasc Pharmacol , vol.52 , pp. 467-473
    • Zhao, G.1    Serpllion, S.2    Shryock, J.3    Messina, E.4    Xu, X.5    Ochoa, M.6
  • 24
    • 34347232707 scopus 로고    scopus 로고
    • Caffeine attenuates the duration of coronary vasodilation and changes in hemodynamics induced by regadenoson (CVT-3146), a novel adenosine A2A receptor agonist
    • DOI 10.1097/FJC.0b013e318046f364, PII 0000534420070600000005
    • Zhao G, Messina E, Xu X, Ochoa M, Sun HL, Leung K, et al. Caffeine attenuates the duration of coronary vasodilation and changes in hemodynamics induced by regadenoson (CVT-3146), a novel adenosine A2A receptor agonist. J Cardiovasc Pharmacol 2007;49:369-75. (Pubitemid 47000311)
    • (2007) Journal of Cardiovascular Pharmacology , vol.49 , Issue.6 , pp. 369-375
    • Zhao, G.1    Messina, E.2    Xu, X.3    Ochoa, M.4    Sun, H.-L.5    Leung, K.6    Shryock, J.7    Belardinelli, L.8    Hintze, T.H.9
  • 26
    • 79955945935 scopus 로고    scopus 로고
    • Effects of apadenoson, a selective adenosine A2a receptor agonis for myocardial perfusion imaging, on coronary blood flow velocity in conscious patients
    • (Abstract)
    • Kern MJ, Hodgson JM, Dib N, Mittleman RS, Crane PD. Effects of apadenoson, a selective adenosine A2a receptor agonis for myocardial perfusion imaging, on coronary blood flow velocity in conscious patients. Circulation 2006;114:582. (Abstract).
    • (2006) Circulation , vol.114 , pp. 582
    • Kern, M.J.1    Hodgson, J.M.2    Dib, N.3    Mittleman, R.S.4    Crane, P.D.5
  • 29
    • 62949173623 scopus 로고    scopus 로고
    • Differences in heart rate response to adenosine and regadenoson in patients with and without diabetes mellitus
    • Hage FG, Heo J, Franks B, Belardinelli L, Blackburn B, Wang W, et al. Differences in heart rate response to adenosine and regadenoson in patients with and without diabetes mellitus. Am Heart J 2009;157:771-6.
    • (2009) Am Heart J , vol.157 , pp. 771-776
    • Hage, F.G.1    Heo, J.2    Franks, B.3    Belardinelli, L.4    Blackburn, B.5    Wang, W.6
  • 30
    • 77649112594 scopus 로고    scopus 로고
    • Blunting of the heart rate response to adenosine and regadenoson in relation to hyperglycemia and the metabolic syndrome
    • Hage FG, Perry G, Heo J, Iskandrian AE. Blunting of the heart rate response to adenosine and regadenoson in relation to hyperglycemia and the metabolic syndrome. Am J Cardiol 2010;105:839-43.
    • (2010) Am J Cardiol , vol.105 , pp. 839-843
    • Hage, F.G.1    Perry, G.2    Heo, J.3    Iskandrian, A.E.4
  • 32
    • 38149102530 scopus 로고    scopus 로고
    • Interaction of caffeine with regadenoson-induced hyperemic myocardial blood flow as measured by positron emission tomography: A randomized, double-blind, placebo-controlled crossover trial
    • Gaemperli O, Schepis T, Koepfli P, Siegrist PT, Fleischman S, Nguyen P, et al. Interaction of caffeine with regadenoson-induced hyperemic myocardial blood flow as measured by positron emission tomography: A randomized, double-blind, placebo-controlled crossover trial. J Am Coll Cardiol 2008;51:328-9.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 328-329
    • Gaemperli, O.1    Schepis, T.2    Koepfli, P.3    Siegrist, P.T.4    Fleischman, S.5    Nguyen, P.6
  • 33
    • 68549135184 scopus 로고    scopus 로고
    • Regadenoson induces comparable left ventricular perfusion defects as adenosine: A quantitative analysis from the ADVANCE MPI 2 trial
    • Mahmarian JJ, Cerqueira MD, Iskandrian AE, Bateman TM, Thomas GS, Hendel RC, et al. Regadenoson induces comparable left ventricular perfusion defects as adenosine: A quantitative analysis from the ADVANCE MPI 2 trial. JACC Cardiovasc Imaging 2009;2:959-68.
    • (2009) JACC Cardiovasc Imaging , vol.2 , pp. 959-968
    • Mahmarian, J.J.1    Cerqueira, M.D.2    Iskandrian, A.E.3    Bateman, T.M.4    Thomas, G.S.5    Hendel, R.C.6
  • 34
    • 43549099776 scopus 로고    scopus 로고
    • 2a agonist regadenoson versus adenosine in myocardial perfusion imaging. Integrated advance-mpi trial results
    • DOI 10.1016/j.jcmg.2008.02.003, PII S1936878X08000326
    • Cerqueira MD, Nguyen P, Staehr P, Underwood SR, Iskandrian AE. Effects of age, gender, obesity, and diabetes on the efficacy and safety of the selective A2A agonist regadenoson versus adenosine in myocardial perfusion imaging integrated ADVANCE-MPI trial results. JACC Cardiovasc Imaging 2008;1:307-16. (Pubitemid 351676842)
    • (2008) JACC: Cardiovascular Imaging , vol.1 , Issue.3 , pp. 307-316
    • Cerqueira, M.D.1    Nguyen, P.2    Staehr, P.3    Underwood, S.R.4    Iskandrian, A.E.5
  • 35
    • 44149105870 scopus 로고    scopus 로고
    • Safety of regadenoson, an adenosine A2A receptor agonist for myocardial perfusion imaging, in mild asthma and moderate asthma patients: A randomized, double-blind, placebocontrolled trial
    • Leaker BR, O'Connor B, Hansel TT, Barnes PJ, Meng L, Mathur VS, et al. Safety of regadenoson, an adenosine A2A receptor agonist for myocardial perfusion imaging, in mild asthma and moderate asthma patients: A randomized, double-blind, placebocontrolled trial. J Nucl Cardiol 2008;15:329-36.
    • (2008) J Nucl Cardiol , vol.15 , pp. 329-336
    • Leaker, B.R.1    O'Connor, B.2    Hansel, T.T.3    Barnes, P.J.4    Meng, L.5    Mathur, V.S.6
  • 36
    • 44149118607 scopus 로고    scopus 로고
    • Safety of regadenoson, a selective adenosine A2A agonist, in patients with chronic obstructive pulmonary disease: A randomized, double-blind, placebo-controlled trial (RegCOPD trial)
    • Thomas GS, Tammelin BR, Schiffman GL, Marquez R, Rice DL, Milikien D, et al. Safety of regadenoson, a selective adenosine A2A agonist, in patients with chronic obstructive pulmonary disease: A randomized, double-blind, placebo-controlled trial (RegCOPD trial). J Nucl Cardiol 2008;15:319-28.
    • (2008) J Nucl Cardiol , vol.15 , pp. 319-328
    • Thomas, G.S.1    Tammelin, B.R.2    Schiffman, G.L.3    Marquez, R.4    Rice, D.L.5    Milikien, D.6
  • 37
    • 73449123101 scopus 로고    scopus 로고
    • Safety of binodenoson, a selective adenosine A2A receptor agonist vasodilator pharmacological stress agent, in healthy subjects with mild intermittent asthma
    • Murray JJ, Weiler JM, Schwartz LB, Busse WW, Katial RK, Lockey RF, et al. Safety of binodenoson, a selective adenosine A2A receptor agonist vasodilator pharmacological stress agent, in healthy subjects with mild intermittent asthma. Circ Cardiovasc Imaging 2009;2:492-8.
    • (2009) Circ Cardiovasc Imaging , vol.2 , pp. 492-498
    • Murray, J.J.1    Weiler, J.M.2    Schwartz, L.B.3    Busse, W.W.4    Katial, R.K.5    Lockey, R.F.6
  • 40
    • 67649994719 scopus 로고    scopus 로고
    • The RegEx trial: A randomized, double-blind, placebo- and active-controlled pilot study combining regadenoson, a selective A(2A) adenosine agonist, with low-level exercise, in patients undergoing myocardial perfusion imaging
    • Thomas GS, Thompson RC, Miyamoto MI, Ip TK, Rice DL, Milikien D, et al. The RegEx trial: A randomized, double-blind, placebo- and active-controlled pilot study combining regadenoson, a selective A(2A) adenosine agonist, with low-level exercise, in patients undergoing myocardial perfusion imaging. J Nucl Cardiol 2009;16:63-72.
    • (2009) J Nucl Cardiol , vol.16 , pp. 63-72
    • Thomas, G.S.1    Thompson, R.C.2    Miyamoto, M.I.3    Ip, T.K.4    Rice, D.L.5    Milikien, D.6
  • 41
    • 77956965037 scopus 로고    scopus 로고
    • Lessons from regadenoson and low-level treadmill/regadenoson myocardial perfusion imaging: Initial clinical experience in 1263 patients
    • Kwon DH, Cerqueira MD, Young R, Houghtaling P, Lieber E, Menon V, et al. Lessons from regadenoson and low-level treadmill/regadenoson myocardial perfusion imaging: Initial clinical experience in 1263 patients. J Nucl Cardiol 2010;17:853-7.
    • (2010) J Nucl Cardiol , vol.17 , pp. 853-857
    • Kwon, D.H.1    Cerqueira, M.D.2    Young, R.3    Houghtaling, P.4    Lieber, E.5    Menon, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.