Houttuynia cordata inhibits lipopolysaccharide-induced rapid pulmonary fibrosis by up-regulating IFN-γ and inhibiting the TGF-β1/Smad pathway

International Immunopharmacology

Volumn 13, Issue 3, 2012, Pages 331-340

  Du, Shaohui ^a   Li, Hui ^a   Cui, Yinghai ^b   Yang, Lina ^a   Wu, Jingjing ^a   Huang, Haiyuan ^a   Chen, Yangyan ^a   Huang, Wei ^a   Zhang, Rong ^a   Yang, Jun ^a   Chen, Dongfeng ^a   Li, Yiwei ^a   Zhang, Saixia ^a   Zhou, Jianhong ^a   Wei, Zhijun ^a   Chow, Ngai Tan ^c  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^b LIAONING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Houttuynia cordata vapor extract; IFN ; Lipopolysaccharide; Rapid pulmonary fibrosis; TGF 1

Indexed keywords

AMINO ACID; BORNYL ACETATE; DEXAMETHASONE; GAMMA INTERFERON; HOUTTUYNIA CORDATA EXTRACT; HYDROXYPROLINE; INTERLEUKIN 4; KETONE DERIVATIVE; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; METHYL N NONYLKETONE; SMAD PROTEIN; STAT1 PROTEIN; STAT6 PROTEIN; TERPINEN 4 OL; TERPINEOL; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD EXAMINATION; CELL LINE; CELL STRAIN 3T3; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG MEGADOSE; DRY WEIGHT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GAS CHROMATOGRAPHY; HEMATOXYLIN EOSIN STAINING; HOUTTUYNIA CORDATA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; LOW DRUG DOSE; LUNG FIBROSIS; LUNG LAVAGE; MALE; MASS SPECTROMETER; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RAPID PULMONARY FIBROSIS; RAT; STAINING; UPREGULATION; VAN GIESON STAINING; VAPOR; WESTERN BLOTTING;

ACUTE LUNG INJURY; ANIMALS; CELL LINE; DEXAMETHASONE; DRUGS, CHINESE HERBAL; FEMALE; HOUTTUYNIA; INTERFERON-GAMMA; INTERLEUKIN-4; LIPOPOLYSACCHARIDES; MALE; MICE; NIH 3T3 CELLS; PULMONARY FIBROSIS; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SMAD PROTEINS; STAT6 TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84861469011     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.03.011     Document Type: Article

References (31)

1. Kolb MR, Richeldi L. Viruses and acute exacerbations of idiopathic pulmonary fibrosis: rest in peace? Am J Respir Crit Care Med 2011;183:1583-4.
2. de Boer K, Vandemheen KL, Tullis E, et al. Exacerbation frequency and clinical outcomes in adult patients with cystic fibrosis. Thorax 2011;66:680-5.
3. World Health Organization. The World Health Report 2007 - A safer future: global public health security in the 21st century vi.
4. Dos Santos CC. Advances in mechanisms of repair and remodelling in acute lung injury. Intensive Care Med 2008;34:619-30. (Pubitemid 351660085)
5. Chambers RC. Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention? Br J Pharmacol 2008;153:s367-78. (Pubitemid 351340998)
6. Budinger GR, Chandel NS, Donnelly HK, et al. Active transforming growth factor-beta1 activates the procollagen I promoter in patients with acute lung injury. Intensive Care Med 2005;31:121-8. (Pubitemid 40174291)
7. Hayashi K, Kamiya M, Hayashi T. Virucidal effects of the steam distillate from Houttuynia cordata and its components on HSV-1, influenza virus, and HIV. Planta Med 1995;61(3):237-41.
8. Chinese Thoracic Society, CMA. Consensus of the clinical management of severe acute repiratory syndrome. Chin J Tuberc Respir Dis 2003;26:323-4.
9. Lau KM, Lee KM, KoonCM, Cheung CS, Lau CP, Ho HM, et al. Immunomodulatory and anti-SARS activities of Houttuynia cordata. J Ethnopharmacol 2008;118(1):79-85.
10. Lee JS, Kim IS, Kim JH, Kim JS, Kim DH, Yun CY. Suppressive effects of Houttuynia cordata Thunb (Saururaceae) extract on Th2 immune response. J Ethnopharmacol 2008;117(1):34-40.
11. Ren X, Sui X, Yin J. The effect of Houttuynia cordata injection on pseudorabies herpesvirus (PrV) infection in vitro. Pharm Biol 2011 Feb;49(2):161-6.
12. Li W, Zhou P, Zhang Y, He L. Houttuynia cordata, a novel and selective COX-2 inhibitor with anti-inflammatory activity. J Ethnopharmacol 2011 Jan 27;133(2):922-7.
13. Zeng Zhong-Da, Liang Yi-Zeng, Zhang Ting, Chau Foo-Tim, Wang Ya-Li. Orthogonal projection (OP) technique applied to pattern recognition of fingerprints of the herbal medicine Houttuynia cordata Thunb. and its final injection products. Anal Bioanal Chem 2006;385:392-400.
14. Shin S, Joo SS, Jeon JH, Park D, Jang MJ, Kim TO, et al. Anti-inflammatory effects of a Houttuynia cordata supercritical extract. J Vet Sci Sep. 2010;11(3):273-5.
15. Tan Z, Chao Z, Sui Y, Liu H, Wu X, Sun J, et al. Effect of Tween 80 on yuxingcao injection and volatile oils from Houttuynia cordata. Zhongguo Zhong Yao Za Zhi Jan. 2011;36(2):175-9 [Article in Chinese].
16. Li H, Du S, Yang L, Chen Y, Huang W, Zhang R, et al. Rapid pulmonary fibrosis induced by acute lung injury via a lipopolysaccharide three-hit regimen. Innate Immun 2009;15:143-54.
17. Liu G, Xiang H, Tang X, Zhang K, Wu X, Wang X, et al. Transcriptional and functional analysis shows sodium houttuyfonate-mediated inhibition of autolysis in Staphylococcus aureus. Molecules 2011 Oct 21;16(10):8848-65.
18. Gertsch J. How scientific is the science in ethnopharmacology? Historical perspectives and epistemological problems. J Ethnopharmacol 2009;122(2):177-83.
19. Hassan SB, Gali-Muhtasib H, Göransson H, Larsson R. Alpha terpineol: a potential anticancer agent which acts through suppressing NF-kappaB signalling. Anticancer Res 2010;30(6):1911-9.
20. Tung Yu-Tang, Chua Meng-Thong, Wang Sheng-Yang, Chang Shang-Tzen. Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs. Bioresour Technol 2008;99:3908-13.
21. Ng LT, Yen FL, Liao CW, Lin CC. Protective effect of Houttuynia cordata extract on bleomycin-induced pulmonary fibrosis in rats. Am J Chin Med 2007;35(3):465-75.
22. Ministry of Health of the People's Republic of China. Discharge guideline for patients diagnosed as severe acute respiratory syndrome; 2003.
23. Shea LM, Beehler C, Schwartz M, Shenkar R, Tuder R, Abraham E. Hyperoxia activates NF-kappaB and increases TNF-alpha and IFN-gamma gene expression in mouse pulmonary lymphocytes. J Immunol 1996;157:3902-8. (Pubitemid 126449298)
24. Sainz Jr B, Mossel EC, Peters CJ, Garry RF. Interferon-beta and interferon-gamma synergistically inhibit the replication of severe acute respiratory syndrome-associated coronavirus (SARS-CoV). Virology 2004;329:11-7. (Pubitemid 39346024)
25. Khoufache K, LeBouder F, Morello E, Laurent F, Riffault S, Andrade-Gordon P, et al. Protective role for protease-activated receptor-2 against influenza virus pathogenesis via an IFN-gamma-dependent pathway. J Immunol 2009;182:7795-802.
26. Attisano L, Wrana JL. Signal transduction by the TGF-beta superfamily. Science 2002;296:1646-7.
27. Frank S, Madlener M, Werner S. Transforming growth factors beta1, beta2, and beta3 and their receptors are differentially regulated during normal and impaired wound healing. J Biol Chem 1996;271:10188-93. (Pubitemid 26131583)
28. Grande JP. Role of transforming growth factor-beta in tissue injury and repair. Proc Soc Exp Biol Med 1997;214:27-40.
29. Nakao A, Fujii M, Matsumura R, Kumano K, Saito Y, Miyazono K, et al. Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice. J Clin Invest 1999;104:5-11. (Pubitemid 29534339)
30. Xie S, Sukkar MB, Issa R, Khorasani NM, Chung KF. Mechanisms of induction of airway smooth muscle hyperplasia by transforming growth factor-beta. Am J Physiol Lung Cell Mol Physiol 2007;293:L245-53. (Pubitemid 47080733)
31. Ulloa L, Doody J, Massague J. Inhibition of transforming growth factor-beta/Smad signalling by the interferon-gamma/STAT pathway. Nature 1999;397:710-3.