Immunomodulatory and anti-SARS activities of Houttuynia cordata

Journal of Ethnopharmacology

Volumn 118, Issue 1, 2008, Pages 79-85

  Lau, Kit Man ^a   Lee, Kin Ming ^a   Koon, Chi Man ^a   Cheung, Crystal Sao Fong ^a   Lau, Ching Po ^a   Ho, Hei Ming ^a   Lee, Mavis Yuk Ha ^a   Au, Shannon Wing Ngor ^a   Cheng, Christopher Hon Ki ^a   Lau, Clara Bik San ^a   Tsui, Stephen Kwok Wing ^a   Wan, David Chi Cheong ^a   Waye, Mary Miu Yee ^a   Wong, Kam Bo ^a   Wong, Chun Kwok ^a   Lam, Christopher Wai Kei ^a   Leung, Ping Chung ^a   Fung, Kwok Pui ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

3C like protease; Anti viral; Houttuynia cordata; Immunomodulation; RNA dependent RNA polymerase; SARS

Indexed keywords

HOUTTUYNIA CORDATA EXTRACT; INTERLEUKIN 10; INTERLEUKIN 2; PROTEINASE; RNA DIRECTED RNA POLYMERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; FLOW CYTOMETRY; HOUTTUYNIA CORDATA; IMMUNOMODULATION; IMMUNOSTIMULATION; INFECTION PREVENTION; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; SINGLE DRUG DOSE; SPLEEN LYMPHOCYTE; TOXICITY TESTING; VIRUS VIRULENCE;

ACUTE TOXICITY TESTS; ADMINISTRATION, ORAL; ANIMALS; ANTIVIRAL AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CHINA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FEMALE; FLOW CYTOMETRY; MICE; MICE, INBRED BALB C; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; SPLEEN;

ANIMALIA; HOUTTUYNIA CORDATA; SARS CORONAVIRUS; SAURURACEAE;

EID: 44149118848     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2008.03.018     Document Type: Article

References (31)

1. Al R.H., Xie Y., and Hagedorn C.H. Expression of recombinant hepatitis C virus non-structural protein 5B in Escherichia coli. Virus Research 53 (1998) 141-149
2. Anand K., Ziebuhr J., Wadhwani P., Mesters J.R., and Hilgenfeld R. Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs. Science 300 (2003) 1763-1767
3. Anon. Herba Houttuynia. In: Zheng H.Z., Dong Z.H., and She J. (Eds). Modern Study of Traditional Chinese Medicine vol. 3 (1997), Xue Yuan Press, Beijing 2983-3003
4. Chang J.S., Chiang L.C., Chen C.C., Liu L.T., Wang K.C., and Lin C.C. Antileukemic activity of Bidens pilosa L. var. minor (Blume) Sherff and Houttuynia cordata Thunb. American Journal of Chinese Medicine 29 (2001) 303-312
5. Chen Y.Y., Liu J.F., Chen C.M., Chao P.Y., and Chang T.J. A study of the antioxidative and antimutagenic effects of Houttuynia cordata Thunb. using an oxidized frying oil-fed model. Journal of Nutritional Science & Vitaminology 49 (2003) 327-333
6. Cheng A., Zhang W., Xie Y., Jiang W., Arnold E., Sarafianos S.G., and Ding J. Expression, purification, and characterization of SARS coronavirus RNA polymerase. Virology 335 (2005) 165-176
7. Chiang L.C., Chang J.S., Chen C.C., Ng L.T., and Lin C.C. Anti-Herpes simplex virus activity of Bidens pilosa and Houttuynia cordata. American Journal of Chinese Medicine 31 (2003) 355-362
8. Cho E.J., Yokozawa T., Rhyu D.Y., Kim H.Y., Shibahara N., and Park J.C. The inhibitory effects of 12 medicinal plants and their component compounds on lipid peroxidation. American Journal of Chinese Medicine 31 (2003) 907-917
9. Gan Y.R., Huang H., Huang Y.D., Rao C.M., Zhao Y., Liu J.S., Wu L., and Wei D.Q. Synthesis and activity of an octapeptide inhibitor designed for SARS coronavirus main proteinase. Peptides 27 (2006) 622-625
10. Hayashi K., Kamiya M., and Hayashi T. Virucidal effects of the steam distillate from Houttuynia cordata and its components on HSV-1, influenza virus, and HIV. Planta Medica 61 (1995) 237-241
11. He Z., Zhao C., Dong Q., Zhuang H., Song S., Peng G., and Dwyer D.E. Effects of severe acute respiratory syndrome (SARS) coronavirus infection on peripheral blood lymphocytes and their subsets. International Journal of Infectious Diseases 9 (2005) 323-330
12. Kim I.S., Kim J.H., Kim J.S., Yun C.Y., Kim D.H., and Lee J.S. The inhibitory effect of Houttuynia cordata extract on stem cell factor-induced HMC-1 cell migration. Journal of Ethnopharmacology 112 (2007) 90-95
13. Kim S.K., Ryu S.Y., No J., Choi S.U., and Kim Y.S. Cytotoxic alkaloids from Houttuynia cordata. Archives of Pharmacal Research 24 (2001) 518-521
14. Korba B.E., Furman P.A., and Otto M.J. Clevudine: a potent inhibitor of hepatitis B virus in vitro and in vivo. Expert Review of Anti-infective Therapy 4 (2006) 549-561
15. Kuo C.J., Chi Y.H., Hsu J.T., and Liang P.H. Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate. Biochemical & Biophysical Research Communications 318 (2004) 862-867
16. Li G.Z., Chai O.H., Lee M.S., Han E.H., Kim H.T., and Song C.H. Inhibitory effects of Houttuynia cordata water extracts on anaphylactic reaction and mast cell activation. Biological & Pharmaceutical Bulletin 28 (2005) 1864-1868
17. Li T., Qiu Z., Han Y., Wang Z., Fan H., Lu W., Xie J., Ma X., and Wang A. Rapid loss of both CD4+ and CD8+ T lymphocyte subsets during the acute phase of severe acute respiratory syndrome. Chinese Medical Journal 116 (2003) 985-987
18. Lin C.W., Tsai F.J., Tsai C.H., Lai C.C., Wan L., Ho T.Y., Hsieh C.C., and Chao P.D. Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds. Antiviral Research 68 (2005) 36-42
19. Liu J.C. Study on HPLC fingerprint of flavoniods in ultramicro-powders of Houttuynia Cordata Thunb. Science & Technology Review 25 (2007) 45-49
20. Loffler B.M., and Kunze H. Refinement of the Coomassie brilliant blue G assay for quantitative protein determination. Analytical Biochemistry 177 (1989) 100-102
21. Lu H.M., Liang Y.Z., Yi L.Z., and Wu X.J. Anti-inflammatory effect of Houttuynia cordata injection. Journal of Ethnopharmacology 104 (2006) 245-249
22. Ng L.T., Yen F.L., Liao C.W., and Lin C.C. Protective Effect of Houttuynia cordata extract on Bleomycin-induced pulmonary fibrosis in rats. American Journal of Chinese Medicine 35 (2007) 465-475
23. O'Donnell R., Tasker R.C., and Roe M.F. SARS: understanding the coronavirus: apoptosis may explain lymphopenia of SARS. British Medical Journal 327 (2003) 620-627
24. Park E., Kum S., Wang C., Park S.Y., Kim B.S., and Schuller-Levis G. Anti-inflammatory activity of herbal medicines: inhibition of nitric oxide production and tumor necrosis factor-alpha secretion in an activated macrophage-like cell line. American Journal of Chinese Medicine 33 (2005) 415-424
25. Romagnani S. Regulation of the T cell response. Clinical and Experimental Allergy 36 (2006) 1357-1366
26. State Pharmacopoeia Commission of People's Republic of China. Pharmacopoeia of the People's Republic of China 2005 ed vol. I (2005), Chemical Industry Press, Beijing 155
27. Thiel V., Ivanov K.A., Putics A., Hertzig T., Schelle B., Bayer S., Weissbrich B., Snijder E.J., Rabenau H., Doerr H.W., Gorbalenya A.E., and Ziebuhr J. Mechanisms and enzymes involved in SARS coronavirus genome expression. Journal of General Virology 84 (2003) 2305-2315
28. Veldman C., Nagel A., and Hertl M. Type I regulatory T cells in autoimmunity and inflammatory diseases. International Archives of Allergy & Immunology 140 (2006) 174-183
29. Wu Y.S., Lin W.H., Hsu J.T., and Hsieh H.P. Antiviral drug discovery against SARS-CoV. Current Medicinal Chemistry 13 (2006) 2003-2020
30. Yamashita T., Kaneko S., Shirota Y., Qin W., Nomura T., Kobayashi K., and Murakami S. RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the C-terminal region. Journal of Biological Chemistry 273 (1998) 15479-15486
31. Yu X.Y., Zhang Y.S., Han C.W., Wang P., Xue X.J., and Cong Y.L. Change of T lymphocyte and its activated subsets in SARS patient. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 25 (2003) 542-546