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Volumn 30, Issue 1, 2012, Pages 49-56

Markers of activated inflammatory cells correlate with severity of liver damage in children with nonalcoholic fatty liver disease

Author keywords

CD163; CD3; CD45; Children; Kupffer cells; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis

Indexed keywords

CD163 ANTIGEN; CD3 ANTIGEN; CD45 ANTIGEN;

EID: 84861467791     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.965     Document Type: Article
Times cited : (54)

References (54)
  • 1
    • 70249094340 scopus 로고    scopus 로고
    • Pediatric nonalcoholic fatty liver disease in 2009
    • Alisi A, Manco M, Vania A and Nobili V: Pediatric nonalcoholic fatty liver disease in 2009. J Pediatr 155: 469-474, 2009.
    • (2009) J Pediatr , vol.155 , pp. 469-474
    • Alisi, A.1    Manco, M.2    Vania, A.3    Nobili, V.4
  • 2
    • 70350241227 scopus 로고    scopus 로고
    • The natural history of non-alcoholic fatty liver disease in children: A follow-up study for up to 20 years
    • Feldstein AE, Charatcharoenwitthaya P, Treeprasertsuk S, Benson JT, Enders FB and Angulo P: The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years. Gut 58: 1538-1544, 2009.
    • (2009) Gut , vol.58 , pp. 1538-1544
    • Feldstein, A.E.1    Charatcharoenwitthaya, P.2    Treeprasertsuk, S.3    Benson, J.T.4    Enders, F.B.5    Angulo, P.6
  • 3
    • 34447633011 scopus 로고    scopus 로고
    • Update on non-alcoholic fatty liver disease in children
    • DOI 10.1016/j.clnu.2007.02.002, PII S0261561407000416
    • Papandreou D, Rousso I and Mavromichalis I: Update on non-alcoholic fatty liver disease in children. Clin Nutr 26: 409-415, 2007. (Pubitemid 47091479)
    • (2007) Clinical Nutrition , vol.26 , Issue.4 , pp. 409-415
    • Papandreou, D.1    Rousso, I.2    Mavromichalis, I.3
  • 4
    • 51549116759 scopus 로고    scopus 로고
    • The obesity epidemic and nonalcoholic fatty liver disease in children
    • Dunn W and Schwimmer JB: The obesity epidemic and nonalcoholic fatty liver disease in children. Curr Gastroenterol Rep 10: 67-72, 2008.
    • (2008) Curr Gastroenterol Rep , vol.10 , pp. 67-72
    • Dunn, W.1    Schwimmer, J.B.2
  • 5
    • 0035083842 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Definition and pathology
    • Brunt EM: Nonalcoholic steatohepatitis: definition and pathology. Semin Liver Dis 21: 3-16, 2001.
    • (2001) Semin Liver Dis , vol.21 , pp. 3-16
    • Brunt, E.M.1
  • 7
    • 52949142682 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A manifestation of the metabolic syndrome
    • Kim CH and Younossi ZM: Nonalcoholic fatty liver disease: a manifestation of the metabolic syndrome. Cleve Clin J Med 75: 721-728, 2008.
    • (2008) Cleve Clin J Med , vol.75 , pp. 721-728
    • Kim, C.H.1    Younossi, Z.M.2
  • 8
    • 67649361544 scopus 로고    scopus 로고
    • Diagnosis and treatment of pediatric nonalcoholic steatohepatitis and the implications for bariatric surgery
    • Pardee PE, Lavine JE and Schwimmer JB: Diagnosis and treatment of pediatric nonalcoholic steatohepatitis and the implications for bariatric surgery. Semin Pediatr Surg 18: 144-151, 2009.
    • (2009) Semin Pediatr Surg , vol.18 , pp. 144-151
    • Pardee, P.E.1    Lavine, J.E.2    Schwimmer, J.B.3
  • 9
    • 75349091707 scopus 로고    scopus 로고
    • Pediatric non-alcoholic fatty liver disease: Preventive and therapeutic value of lifestyle intervention
    • Nobili V, Alisi A and Raponi M: Pediatric non-alcoholic fatty liver disease: preventive and therapeutic value of lifestyle intervention. World J Gastroenterol 15: 6017-6022, 2009.
    • (2009) World J Gastroenterol , vol.15 , pp. 6017-6022
    • Nobili, V.1    Alisi, A.2    Raponi, M.3
  • 10
    • 40849083460 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease: The mist gradually clears
    • de Alwis NM and Day CP: Non-alcoholic fatty liver disease: the mist gradually clears. J Hepatol 48 (Suppl 1): S104-S112, 2008.
    • (2008) J Hepatol , vol.48 , Issue.SUPPL. 1
    • De Alwis, N.M.1    Day, C.P.2
  • 12
    • 77958183243 scopus 로고    scopus 로고
    • Novel insights into the pathophysiology of nonalcoholic fatty liver disease
    • Feldstein AE: Novel insights into the pathophysiology of nonalcoholic fatty liver disease. Semin Liver Dis 30: 391-401, 2010.
    • (2010) Semin Liver Dis , vol.30 , pp. 391-401
    • Feldstein, A.E.1
  • 13
    • 55649103668 scopus 로고    scopus 로고
    • Insulin resistance, inflammation, and non-alcoholic fatty liver disease
    • Tilg H and Moschen AR: Insulin resistance, inflammation, and non-alcoholic fatty liver disease. Trends Endocrinol Metab 19: 371-379, 2008.
    • (2008) Trends Endocrinol Metab , vol.19 , pp. 371-379
    • Tilg, H.1    Moschen, A.R.2
  • 14
    • 67349205002 scopus 로고    scopus 로고
    • Kupffer cells in non-alcoholic fatty liver disease: The emerging view
    • Baffy G: Kupffer cells in non-alcoholic fatty liver disease: the emerging view. J Hepatol 51: 212-223, 2009.
    • (2009) J Hepatol , vol.51 , pp. 212-223
    • Baffy, G.1
  • 15
    • 33947261669 scopus 로고    scopus 로고
    • Predictors reflecting the pathological severity of non-alcoholic fatty liver disease: Comprehensive study of clinical and immunohistochemical findings in younger Asian patients
    • DOI 10.1111/j.1440-1746.2006.04758.x
    • Park JW, Jeong G, Kim SJ, Kim MK and Park SM: Predictors reflecting the pathological severity of non-alcoholic fatty liver disease: comprehensive study of clinical and immunohistochemical findings in younger Asian patients. J Gastroenterol Hepatol 22: 491-497, 2007. (Pubitemid 46434984)
    • (2007) Journal of Gastroenterology and Hepatology , vol.22 , Issue.4 , pp. 491-497
    • Park, J.-W.1    Jeong, G.2    Kim, S.J.3    Kim, M.K.4    Park, S.M.5
  • 17
    • 34548272744 scopus 로고    scopus 로고
    • Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis
    • DOI 10.1016/j.jhep.2007.04.019, PII S0168827807003017
    • Rivera CA, Adegboyega P, van Rooijen N, Tagalicud A, Allman M and Wallace M: Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis. J Hepatol 47: 571-579, 2007. (Pubitemid 47331747)
    • (2007) Journal of Hepatology , vol.47 , Issue.4 , pp. 571-579
    • Rivera, C.A.1    Adegboyega, P.2    Van Rooijen, N.3    Tagalicud, A.4    Allman, M.5    Wallace, M.6
  • 18
    • 33750999322 scopus 로고    scopus 로고
    • Role of Kupffer cells in host defense and liver disease
    • DOI 10.1111/j.1478-3231.2006.01342.x
    • Bilzer M, Roggel F and Gerbes AL: Role of Kupffer cells in host defense and liver disease. Liver Int 26: 1175-1186, 2006. (Pubitemid 44741204)
    • (2006) Liver International , vol.26 , Issue.10 , pp. 1175-1186
    • Bilzer, M.1    Roggel, F.2    Gerbes, A.L.3
  • 19
    • 33845899370 scopus 로고    scopus 로고
    • Role of Kupffer cells in the pathogenesis of liver disease
    • Kolios G, Valatas V and Kouroumalis E: Role of Kupffer cells in the pathogenesis of liver disease. World J Gastroenterol 12: 7413-7420, 2006. (Pubitemid 46017736)
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.46 , pp. 7413-7420
    • Kolios, G.1    Valatas, V.2    Kouroumalis, E.3
  • 20
    • 77957746634 scopus 로고    scopus 로고
    • Roles of liver innate immune cells in nonalcoholic fatty liver disease
    • Zhan YT and An W: Roles of liver innate immune cells in nonalcoholic fatty liver disease. World J Gastroenterol 16: 4652-4660, 2010.
    • (2010) World J Gastroenterol , vol.16 , pp. 4652-4660
    • Zhan, Y.T.1    An, W.2
  • 21
    • 40049104519 scopus 로고    scopus 로고
    • Natural killer T cells and non-alcoholic fatty liver disease: Fat chews on the immune system
    • DOI 10.3748/wjg.14.487
    • Kremer M and Hines IN: Natural killer T cells and non-alcoholic fatty liver disease: fat chews on the immune system. World J Gastroenterol 14: 487-488, 2008. (Pubitemid 351320862)
    • (2008) World Journal of Gastroenterology , vol.14 , Issue.3 , pp. 487-488
    • Kremer, M.1    Hines, I.N.2
  • 22
    • 77950624359 scopus 로고    scopus 로고
    • The link between hepatosteatosis and cells of the immune system
    • Alisi A, Panera N and Nobili V: The link between hepatosteatosis and cells of the immune system. Hepatology 51: 1472-1473, 2010.
    • (2010) Hepatology , vol.51 , pp. 1472-1473
    • Alisi, A.1    Panera, N.2    Nobili, V.3
  • 23
    • 75449092201 scopus 로고    scopus 로고
    • Toll-like receptor 4: A starting point for proinflammatory signals in fatty liver disease
    • Alisi A, Panera N and Nobili V: Toll-like receptor 4: a starting point for proinflammatory signals in fatty liver disease. Hepatology 51: 714-715, 2010.
    • (2010) Hepatology , vol.51 , pp. 714-715
    • Alisi, A.1    Panera, N.2    Nobili, V.3
  • 24
    • 70350075402 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in the development of fructose induced hepatic steatosis in mice
    • Spruss A, Kanuri G, Wagnerberger S, Haub S, Bischoff SC and Bergheim I: Toll-like receptor 4 is involved in the development of fructose induced hepatic steatosis in mice. Hepatology 50: 1094-1104, 2009.
    • (2009) Hepatology , vol.50 , pp. 1094-1104
    • Spruss, A.1    Kanuri, G.2    Wagnerberger, S.3    Haub, S.4    Bischoff, S.C.5    Bergheim, I.6
  • 25
    • 73449142810 scopus 로고    scopus 로고
    • Kupffer cell and interleukin-12-dependent loss of natural killer T cells in hepatosteatosis
    • Kremer M, Thomas E, Milton RJ, et al: Kupffer cell and interleukin-12-dependent loss of natural killer T cells in hepatosteatosis. Hepatology 51: 130-141, 2010.
    • (2010) Hepatology , vol.51 , pp. 130-141
    • Kremer, M.1    Thomas, E.2    Milton, R.J.3
  • 26
    • 75449101395 scopus 로고    scopus 로고
    • Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity
    • Stienstra R, Saudale F, Duval C, et al: Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity. Hepatology 51: 511-522, 2010.
    • (2010) Hepatology , vol.51 , pp. 511-522
    • Stienstra, R.1    Saudale, F.2    Duval, C.3
  • 27
    • 67649202605 scopus 로고    scopus 로고
    • Call for a European programme in external quality assurance for bone marrow immunohistochemistry; report of a European Bone Marrow Working Group pilot study
    • Torlakovic EE, Naresh K, Kremer M, van der Walt J, Hyjek E and Porwit A: Call for a European programme in external quality assurance for bone marrow immunohistochemistry; report of a European Bone Marrow Working Group pilot study. J Clin Pathol 62: 547-551, 2009.
    • (2009) J Clin Pathol , vol.62 , pp. 547-551
    • Torlakovic, E.E.1    Naresh, K.2    Kremer, M.3    Van Der Walt, J.4    Hyjek, E.5    Porwit, A.6
  • 28
    • 22644445829 scopus 로고    scopus 로고
    • The macrophage scavenger receptor CD163
    • DOI 10.1016/j.imbio.2005.05.010, PII S0171298505000823
    • Fabriek BO, Dijkstra CD and van den Berg TK: The macrophage scavenger receptor CD163. Immunobiology 210: 153-160, 2005. (Pubitemid 41025156)
    • (2005) Immunobiology , vol.210 , Issue.2-4 , pp. 153-160
    • Fabriek, B.O.1    Dijkstra, C.D.2    Van den, B.T.K.3
  • 29
    • 17744387919 scopus 로고    scopus 로고
    • Expression of CD163 (hemoglobin scavenger receptor) in normal tissues, lymphomas, carcinomas, and sarcomas is largely restricted to the monocyte/macrophage lineage
    • DOI 10.1097/01.pas.0000157940.80538.ec
    • Nguyen TT, Schwartz EJ, West RB, Warnke RA, Arber DA and Natkunam Y: Expression of CD163 (hemoglobin scavenger receptor) in normal tissues, lymphomas, carcinomas, and sarcomas is largely restricted to the monocyte/macrophage lineage. Am J Surg Pathol 29: 617-624, 2005. (Pubitemid 40577871)
    • (2005) American Journal of Surgical Pathology , vol.29 , Issue.5 , pp. 617-624
    • Nguyen, T.T.1    Schwartz, E.J.2    West, R.B.3    Warnke, R.A.4    Arber, D.A.5    Natkunam, Y.6
  • 31
    • 0032821965 scopus 로고    scopus 로고
    • Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
    • DOI 10.2337/diacare.22.9.1462
    • Matsuda M and DeFronzo RA: Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22: 1462-1470, 1999. (Pubitemid 29418240)
    • (1999) Diabetes Care , vol.22 , Issue.9 , pp. 1462-1470
    • Matsuda, M.1    DeFronzo, R.A.2
  • 32
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
    • DOI 10.1007/BF00280883
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF and Turner RC: Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419, 1985. (Pubitemid 15018832)
    • (1985) Diabetologia , vol.28 , Issue.7 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 34
    • 78651440632 scopus 로고    scopus 로고
    • Relationship between portal chronic inflammation and disease severity in paediatric non-alcoholic fatty liver disease
    • Alisi A, Bedogni G, De Vito R, Comparcola D, Manco M and Nobili V: Relationship between portal chronic inflammation and disease severity in paediatric non-alcoholic fatty liver disease. Dig Liver Dis 43: 143-146, 2011.
    • (2011) Dig Liver Dis , vol.43 , pp. 143-146
    • Alisi, A.1    Bedogni, G.2    De Vito, R.3    Comparcola, D.4    Manco, M.5    Nobili, V.6
  • 35
    • 70349570846 scopus 로고    scopus 로고
    • The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: Two triggers for one disease?
    • Valenti L, Fracanzani AL and Fargion S: The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: two triggers for one disease? Semin Immunopathol 31: 359-369, 2009.
    • (2009) Semin Immunopathol , vol.31 , pp. 359-369
    • Valenti, L.1    Fracanzani, A.L.2    Fargion, S.3
  • 36
    • 25844437136 scopus 로고    scopus 로고
    • Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease
    • DOI 10.1002/hep.20826
    • Li Z, Soloski MJ and Diehl AM: Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease. Hepatology 42: 880-885, 2005. (Pubitemid 41401126)
    • (2005) Hepatology , vol.42 , Issue.4 , pp. 880-885
    • Li, Z.1    Soloski, M.J.2    Diehl, A.M.3
  • 37
    • 37549022688 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • DOI 10.1016/j.febslet.2007.11.057, PII S0014579307012082
    • de Luca C and Olefsky JM: Inflammation and insulin resistance. FEBS Lett 582: 97-105, 2008. (Pubitemid 50010731)
    • (2008) FEBS Letters , vol.582 , Issue.1 , pp. 97-105
    • De Luca, C.1    Olefsky, J.M.2
  • 38
    • 36349010120 scopus 로고    scopus 로고
    • A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury
    • DOI 10.1002/hep.21823
    • Ma X, Hua J, Mohamood AR, Hamad AR, Ravi R and Li Z: A high fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury. Hepatology 46: 1519-1529, 2007. (Pubitemid 350155534)
    • (2007) Hepatology , vol.46 , Issue.5 , pp. 1519-1529
    • Ma, X.1    Hua, J.2    Mohamood, A.R.3    Hamad, A.R.A.4    Ravi, R.5    Li, Z.6
  • 39
    • 34247857663 scopus 로고    scopus 로고
    • Obesity, Inflammation, and Insulin Resistance
    • DOI 10.1053/j.gastro.2007.03.059, PII S0016508507005859
    • Shoelson SE, Herrero L and Naaz A: Obesity, inflammation, and insulin resistance. Gastroenterology 132: 2169-2180, 2007. (Pubitemid 46693756)
    • (2007) Gastroenterology , vol.132 , Issue.6 , pp. 2169-2180
    • Shoelson, S.E.1    Herrero, L.2    Naaz, A.3
  • 41
    • 57149093788 scopus 로고    scopus 로고
    • NK and NKT cells in liver injury and fibrosis
    • Notas G, Kisseleva T and Brenner D: NK and NKT cells in liver injury and fibrosis. Clin Immunol 130: 16-26, 2009.
    • (2009) Clin Immunol , vol.130 , pp. 16-26
    • Notas, G.1    Kisseleva, T.2    Brenner, D.3
  • 43
    • 79551592245 scopus 로고    scopus 로고
    • Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease
    • Alisi A, Da Sacco L, Bruscalupi G, et al: Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease. Lab Invest 91: 283-293, 2011.
    • (2011) Lab Invest , vol.91 , pp. 283-293
    • Alisi, A.1    Da Sacco, L.2    Bruscalupi, G.3
  • 45
    • 35649007401 scopus 로고    scopus 로고
    • Viral and Host Factors Induce Macrophage Activation and Loss of Toll-Like Receptor Tolerance in Chronic HCV Infection
    • DOI 10.1053/j.gastro.2007.08.003, PII S0016508507014497
    • Dolganiuc A, Norkina O, Kodys K, Catalano D, Bakis G, Marshall C, Mandrekar P, et al: Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance inchronic HCV infection. Gastroenterology 133: 1627-1636, 2007. (Pubitemid 350029734)
    • (2007) Gastroenterology , vol.133 , Issue.5 , pp. 1627-1636
    • Dolganiuc, A.1    Norkina, O.2    Kodys, K.3    Catalano, D.4    Bakis, G.5    Marshall, C.6    Mandrekar, P.7    Szabo, G.8
  • 47
    • 80053467921 scopus 로고    scopus 로고
    • Soluble CD163 is not increased in visceral fat and steatotic liver and is even suppressed by free fatty acids in vitro
    • Bauer S, Weiss TS, Wiest R, Schacherer D, Hellerbrand C, Farkas S, Scherer MN, et al: Soluble CD163 is not increased in visceral fat and steatotic liver and is even suppressed by free fatty acids in vitro. Exp Mol Pathol 91: 733-739, 2011.
    • (2011) Exp Mol Pathol , vol.91 , pp. 733-739
    • Bauer, S.1    Weiss, T.S.2    Wiest, R.3    Schacherer, D.4    Hellerbrand, C.5    Farkas, S.6    Scherer, M.N.7
  • 48
  • 49
    • 0034005303 scopus 로고    scopus 로고
    • Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: Potential mechanism for sensitization to liver damage
    • Guebre-Xabier M, Yang S, Lin HZ, Schwenk R, Krzych U and Diehl AM: Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage. Hepatology 31: 633-640, 2000. (Pubitemid 30118631)
    • (2000) Hepatology , vol.31 , Issue.3 , pp. 633-640
    • Guebre-Xabier, M.1    Yang, S.2    Lin, H.Z.3    Schwenk, R.4    Krzych, U.5    Diehl, A.M.6
  • 50
    • 33745911148 scopus 로고    scopus 로고
    • Favored T helper 1 response in a mouse model of hepatosteatosis is associated with enhanced T cell-mediated hepatitis
    • DOI 10.1002/hep.21221
    • Kremer M, Hines IN, Milton RJ and Wheeler MD: Favored T helper 1 response in a mouse model of hepatosteatosis is associated with enhanced T cell-mediated hepatitis. Hepatology 44: 216-227, 2006. (Pubitemid 44049154)
    • (2006) Hepatology , vol.44 , Issue.1 , pp. 216-227
    • Kremer, M.1    Hines, I.N.2    Milton, R.J.3    Wheeler, M.D.4
  • 51
    • 34548674932 scopus 로고    scopus 로고
    • Association of the frequency of peripheral natural killer T cells with nonalcoholic fatty liver disease
    • Xu CF, Yu CH, Li YM, Xu L, Du J and Shen Z: Association of the frequency of peripheral natural killer T cells with nonalcoholic fatty liver disease. World J Gastroenterol 13: 4504-4508, 2007. (Pubitemid 47412416)
    • (2007) World Journal of Gastroenterology , vol.13 , Issue.33 , pp. 4504-4508
    • Xu, C.-F.1    Yu, C.-H.2    Li, Y.-M.3    Xu, L.4    Du, J.5    Shen, Z.6
  • 52
    • 0032169234 scopus 로고    scopus 로고
    • Rapid death and regeneration of NKT cells in anti-CD3epsilon- or IL-12- treated mice: A major role for bone marrow in NKT cell homeostasis
    • DOI 10.1016/S1074-7613(00)80617-2
    • Eberl G and MacDonald HR: Rapid death and regeneration of NKT cells in anti-CD3epsilon- or IL-12-treated mice: a major role for bone marrow in NKT cell homeostasis. Immunity 9: 345-353, 1998. (Pubitemid 28462755)
    • (1998) Immunity , vol.9 , Issue.3 , pp. 345-353
    • Eberl, G.1    MacDonald, H.R.2
  • 53
    • 78651323085 scopus 로고    scopus 로고
    • Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet
    • Miyagi T, Takehara T, Uemura A, et al: Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet. J Gastroenterol 45: 1247-1254, 2010.
    • (2010) J Gastroenterol , vol.45 , pp. 1247-1254
    • Miyagi, T.1    Takehara, T.2    Uemura, A.3
  • 54
    • 79960299110 scopus 로고    scopus 로고
    • Probiotics as an emerging therapeutic strategy to treat NAFLD: Focus on molecular and biochemical mechanisms
    • Iacono A, Raso GM, Canani RB, Calignano A and Meli R: Probiotics as an emerging therapeutic strategy to treat NAFLD: focus on molecular and biochemical mechanisms. J Nutr Biochem 22: 699-711, 2011.
    • (2011) J Nutr Biochem , vol.22 , pp. 699-711
    • Iacono, A.1    Raso, G.M.2    Canani, R.B.3    Calignano, A.4    Meli, R.5


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