Insulin resistance in women with hirsutism

Archives of Medical Science

Volumn 8, Issue 2, 2012, Pages 342-346

  Cebeci, Filiz ^a   Onsun, Nahide ^a   Mert, Meral ^b  

^a VAKIF GUREBA HOSPITAL   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Idiopathic hirsutism; Insulin resistance; Non obese women

Indexed keywords

INSULIN;

ADULT; ARTICLE; BODY MASS; CLINICAL ARTICLE; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HIRSUTISM; HOMEOSTASIS MODEL ASSESSMENT; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; OBESITY; OVARY POLYCYSTIC DISEASE;

EID: 84861464753     PISSN: 17341922     EISSN: None     Source Type: Journal    
DOI: 10.5114/aoms.2012.28563     Document Type: Article

References (27)

1. Aziz R, Sanchez LA, Knochenhauer ES, et al. Androgen excess in women: experience with over 1000 consecutive patients. J Clin Endoc Metab 2004; 89: 453-62. (Pubitemid 38269843)
2. Aziz R, Carmina E, Sawaya ME. Idiopathic hirsutism. Endoc Rev 2000; 21: 347-62. (Pubitemid 32279644)
3. Rossi R, Tauchmanoca L, Luciano A, et al. Functional hyperandrogenism detected by corticotropin and GnRHanaloque stimulation tests in women affected by apparently idiopathic hirsutism. J Endocrinol Invest 2001; 24: 491-8. (Pubitemid 32691161)
4. Rotterdam ESHRE/ASRM-sponsored PCOS Consensus Workshop Group. Revised consensus on diagnostic criteria and long term healty risks related to polycystic ovary syndrome. Human Reprod 2004; 19: 41-7.
5. Ferriman D, Gallwey JD. Clinical assessment of body hair growth in women. J Clin Endoc Metab 1961; 21: 1440-7.
6. Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-9. (Pubitemid 15018832)
7. Burghen G, Givens J, Kitabchi A. Correlation of hyperan - drogenism with hyperinsulinemia in polycystic ovarian disease. J Clin Endocrinol Metab 1980; 50: 113-6. (Pubitemid 10203585)
8. Rosenfield RL. Polycystic ovary syndrome and insulinresistant hyperinsulinemia. J Am Acad Dermatol 2001; 45: 95-104.
9. Dunaif A. Insulin action in the polycystic ovary syndrome. End Metab Clin Nort Am 1999; 28: 341-59. (Pubitemid 29242717)
10. Rosenfield RL, Barnes RB, Cara JF, et al. Dysregulation of cytochrome P450c17alpha as the cause of polycystic ovary syndrome. Fertil Steril 1990; 53: 785-91. (Pubitemid 20180464)
11. Vrbikova J, Hainer V. Obesity and polycystic ovary syndrome. Obes Facts 2009; 2: 26-35.
12. O'Connor A, Gibney J, Roche HM. Metabolic and hormonal aspects of polycystic ovary syndrome: the impact of diet. Proc Nutr Soc 2010; 10: 1-8.
13. Ehrmann DA, Barnes RB, Rosenfield RL, et al. Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care 1999; 22: 141-6. (Pubitemid 29028311)
14. Chang RJ, Nakamura RM, Judd HL, et al. Insulin resistance in nonobese patients with polycystic ovarian disease. J Clin Endocrinol Metab 1983; 57: 356-9. (Pubitemid 13032489)
15. Dunaif A, Segal KR, Futterweit W, et al. Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes 1989; 38: 1165-73.
16. Dunaif A, Segal KR, Shelley DR, et al. Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome. Diabetes 1992; 41: 1257-66.
17. Dale PO, Tomb T, Voalir S, et al. Body weight, hyperinsulinemia, and gonadotrophin levels in the polycystic ovary syndrome: evidence of two distinct populations. Fertil Steril 1992; 58: 487-91.
18. Vrbikova J, Cibula D, Dvorakova K, et al. Insulin sensitivity in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2004; 89: 2942-5. (Pubitemid 38766389)
19. Ketel IJ, Stehouwer CD, Serné EH, et al. Obese but not normal-weight women with polycystic ovary syndrome are characterized by metabolic and microvascular insulin resistance. J Clin Endocrinol Metab 2008; 93: 3365-72.
20. Takeuchi T, Tsutsumi O, Taketani Y. Abnormal response of insulin to glucose loading and assessment of insulin resistance in non-obese patients with polycystic ovary syndrome. Gynecol Endocrinol 2008; 24: 385-91. (Pubitemid 352032231)
21. Arthur LS, Selvakumar R, Seshadri MS, et al. Hyperinsulinemia in polycystic ovary disease. J Reprod Med 1999; 44: 783-7. (Pubitemid 29446869)
22. Amato MC, Galluzzo A, Merlino S, et al. Lower insulin sensitivity differentiates hirsute from non-hirsute Sicilian women with polycystic ovary syndrome. Eur J Endoc 2006; 155: 859-65. (Pubitemid 46040625)
23. Philpott MP, Sanders DA, Kealey T. Effects of insulin and insulin-like growth factors on cultured human hair follicles: IGF-I at physiologic concentrations is an important regulator of hair follicle growth in vitro. J Invest Dermatol 1994; 102: 857-61. (Pubitemid 24210379)
24. Itami S, Kurata S, Takayasu S. Androgen induction of follicular epithelial cell growth is mediated via insulin-like growth factor-I from dermal papilla cells. Biochem Biophys Res Commun 1995; 212: 988-94.
25. Paoletti AM, Cagnacci A, Orru M, et al. Treatment with flutamide improves hyperinsulinemia in women with idiopathic hirsutism. Fertil Steril 1999; 72: 448-53. (Pubitemid 29414884)
26. Unlühizarci K, Karababa Y, Bayram F, et al. The investigation of insulin resistance in patients with idiopathiv hirsutism. J Clin Endocrinol Metab 2004; 89: 2741-4. (Pubitemid 38766359)
27. Abdel Fattah NS, Darwish YW. Is there a role for insulin resistance in nonobese patients with idiopathic hirsutism? Br J Dermatol 2009; 160: 1011-5.