Elevated BAFF Levels in the Cerebrospinal Fluid of Patients with Neuro-Behçet's Disease: BAFF is Correlated with Progressive Dementia and Psychosis

Scandinavian Journal of Immunology

Volumn 75, Issue 6, 2012, Pages 633-640

  Sumita, Y ^a   Murakawa, Y ^a   Sugiura, T ^a   Wada, Y ^a   Nagai, A ^a   Yamaguchi, S ^a  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR; COLCHICINE; CYCLOPHOSPHAMIDE; INTERLEUKIN 6; METHOTREXATE; MINOCYCLINE; PREDNISOLONE;

ADOLESCENT; ADULT; AGED; ARTICLE; ASEPTIC MENINGITIS; BEHCET DISEASE; BRAIN STEM; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CONTROLLED STUDY; DEMENTIA; DISEASE CONTROL; DISEASE COURSE; EPIDEMIC; FEMALE; HUMAN; MALE; MULTIPLE SCLEROSIS; NEURO BEHCET DISEASE; NEUROPSYCHIATRY; PRIORITY JOURNAL; PSYCHOSIS; SPINAL CORD DISEASE;

B-CELL ACTIVATING FACTOR; BEHCET SYNDROME; DEMENTIA; DISEASE PROGRESSION; HUMANS; PSYCHOTIC DISORDERS;

EID: 84861464525     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2012.02694.x     Document Type: Article

References (26)

1. Abraham S, Rajeev E, Girija AS. Neuro-Behcet's disease. J Assoc Physicians India 2000;48:838-41.
2. Benamour S, Naji T, Alaoui FZ, El-Kabli H, El-Aidouni S. [Neurological involvement in Behcet's disease. 154 cases from a cohort of 925 patients and review of the literature]. Rev Neurol (Paris) 2006;162:1084-90.
3. Sakane T, Takeno M, Suzuki N, Inaba G. Behcet's disease. N Engl J Med 1999;21:341.
4. Hirohata S, Isshi K, Oguchi H et al. Cerebrospinal fluid interleukin-6 in progressive Neuro-Behcet's syndrome. Clin Immunol Immunopathol 1997;82:12-7.
5. Hamzaoui K, Hamzaoui A, Ghorbel I, Khanfir M, Houman H. Levels of IL-15 in serum and cerebrospinal fluid of patients with Behcet's disease. Scand J Immunol 2006;64:655-60.
6. Moore PA, Belvedere O, Orr A et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 1999;285:260-3.
7. Schneider P, Mackay F, Steiner V et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 1999;189:1747-56.
8. He B, Chadburn A, Jou E, Schattner EJ, Knowles DM, Cerutti A. Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL. J Immunol 2004;172:3268-79.
9. Nardelli B, Belvedere O, Roschke V et al. Synthesis and release of B-lymphocyte stimulator from myeloid cells. Blood 2001;97:198-204.
10. Scapini P, Nardelli B, Nadali G et al. G-CSF-stimulated neutrophils are a prominent source of functional BLyS. J Exp Med 2003;197:297-302.
11. Ittah M, Miceli-Richard C, Eric Gottenberg J et al. B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjogren's syndrome. Arthritis Res Ther 2006;8:R51.
12. Szodoray P, Alex P, Jonsson MV et al. Distinct profiles of Sjogren's syndrome patients with ectopic salivary gland germinal centers revealed by serum cytokines and BAFF. Clin Immunol 2005;117:168-76.
13. Mackay F, Tangye SG. The role of the BAFF/APRIL system in B cell homeostasis and lymphoid cancers. Curr Opin Pharmacol 2004;4:347-54.
14. Krumbholz M, Theil D, Derfuss T et al. BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. J Exp Med 2005;201:195-200.
15. Khare SD, Sarosi I, Xia XZ et al. Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc Natl Acad Sci U S A 2000;97:3370-5.
16. [no author listed] Criteria for diagnosis of Behcet's disease. International Study Group for Behcet's Disease. Lancet 1990;335:1078-80.
17. Itoh R, Takenaka T, Okitsu-Negishi S, Matsushima K, Mizoguchi M. Interleukin 8 in Behcet's disease. J Dermatol 1994;21:397-404.
18. Archelos JJ, Storch MK, Hartung HP. The role of B cells and autoantibodies in multiple sclerosis. Ann Neurol 2000;47:694-706.
19. Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol 2000;47:707-17.
20. McLean BN, Miller D, Thompson EJ. Oligoclonal banding of IgG in CSF, blood-brain barrier function, and MRI findings in patients with sarcoidosis, systemic lupus erythematosus, and Behcet's disease involving the nervous system. J Neurol Neurosurg Psychiatry 1995;58:548-54.
21. Akman-Demir G, Serdaroglu P, Tasci B. Clinical patterns of neurological involvement in Behcet's disease: evaluation of 200 patients. The Neuro-Behcet Study Group. Brain 1999;122(Pt 11):2171-82.
22. Kidd D, Steuer A, Denman AM, Rudge P. Neurological complications in Behcet's syndrome. Brain 1999;122(Pt 11):2183-94.
23. Suh CH, Park YB, Song J, Lee CH, Lee SK. Oligoclonal B lymphocyte expansion in the synovium of a patient with Behcet's disease. Arthritis Rheum 2001;44:1707-12.
24. Mukhopadhyay A, Ni J, Zhai Y, Yu GL, Aggarwal BB. Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase. J Biol Chem 1999;274:15978-81.
25. Reichenberg A, Yirmiya R, Schuld A et al. Cytokine-associated emotional and cognitive disturbances in humans. Arch Gen Psychiatry 2001;58:445-52.
26. Crupi R, Cambiaghi M, Spatz L et al. Reduced adult neurogenesis and altered emotional behaviors in autoimmune-prone B-cell activating factor transgenic mice. Biol Psychiatry 2010;67:558-66.