The prognostic value of multivoxel magnetic resonance spectroscopy determined metabolite levels in white and grey matter brain tissue for adverse outcome in term newborns following perinatal asphyxia

European Radiology

Volumn 22, Issue 4, 2012, Pages 772-778

  Van Doormaal, Pieter Jan ^a,b   Meiners, Linda C ^a   Ter Horst, Hendrik J ^a   Van Der Veere, Christa N ^a   Sijens, Paul E ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b MEANDER MEDICAL CENTER   (Netherlands)

Author keywords

Asphyxia; Encephalopathy; Magnetic resonance spectroscopy; Metabolism

Indexed keywords

CHOLINE; CREATINE; LACTIC ACID; N ACETYLASPARTIC ACID;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GRAY MATTER; HUMAN; INFANT; MALE; METABOLITE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PERINATAL ASPHYXIA; PRIORITY JOURNAL; PROGNOSIS; SURVIVOR; WHITE MATTER;

ASPHYXIA NEONATORUM; BRAIN; FEMALE; HUMANS; IMAGING, THREE-DIMENSIONAL; INFANT, NEWBORN; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NERVE FIBERS, MYELINATED; NETHERLANDS; NEURONS; PREVALENCE; PROGNOSIS; SURVIVAL ANALYSIS; SURVIVAL RATE;

EID: 84861460814     PISSN: 09387994     EISSN: 14321084     Source Type: Journal    
DOI: 10.1007/s00330-011-2315-z     Document Type: Article

References (31)

1. Thayyil S, Chandrasakaran M, Taylor A et al (2010) Cerebral magnetic resonance biomarkers in neonatal encephalopathy: a meta-analysis. Pediatrics 125:e382-e395
2. Dubowitz LM, Bydder GM (1985) Nuclear magnetic resonance imaging in the diagnosis and follow-up of neonatal cerebral injury. Clin Perinatol 12:243-260
3. Peden CJ, Rutherford MA, Sargentoni J, Cox IJ, Bryant DJ, Dubowitz LMS (1993) Proton spectroscopy of the neonatal brain following hypoxic ischaemic injury. Dev Med Child Neurol 35:502-510
4. Hanrahan JD, Sargentoni J, Azzopardi D et al (1996) Cerebral metabolism within 18 hours of birth asphyxia: a proton magnetic resonance spectroscopy study. Pediatr Res 39:584-590
5. Penrice J, Cady EB, Lorekk A, Wylezinska M et al (1996) Proton spectroscopy of the brain in normal preterm and term infants, and early changes after perinatal hypoxia-ischemia. Pediatr Res 40:6-14
6. Holshouser SA, Ashwal S, Gy L et al (1997) Proton spectroscopy after acute central nervous system injury; outcome prediction in neonates, infants, and children. Radiology 202:487-496
7. Barkovich AJ, Baranski K, Vigneron D et al (1999) Proton MR spectroscopy for the evaluation of brain injury in asphyxiated, term neonates. AJNR Am J Neuroradiol 20:1399-1405
8. Amess PN, Lorek A, Townsend J et al (1999) Early brain proton magnetic resonance spectroscopy and neonatal neurology related to neurodevelopmental outcome at 1 year in term infants after presumed hypoxic-ischaemic brain injury. Dev Med Child Neurol 41:436-445
9. Robertson NJ, Lewis RH, Cowan FM et al (2001) Early increases in brain myo-inosotol measured by proton magnetic resonance spectroscopy in term infants with neonatal encephalopathy. Pediatr Res 50:692-700
10. Groenendaal F, Roelants-van Rijn AM, van der Grond J, Toet MC, de Vries LS (2001) Glutamate in cerebral tissue of asphyxiated neonates during the first week of life demonstrated in vivo using proton magnetic resonance spectroscopy. Biol Neonate 79:254-257
11. Fan G,Wu Z, Chen L, Guo Q, Ye B,Mao J (2003) Hypoxic-ischemic encephalopathy in full-term neonate: correlation of proton MR spectroscopy with MR imaging. Eur J Radiol 45:91-98
12. Brissaud O, Chateil J-F, Bordessoules M, Brun M (2005) Chemical shift imaging and localized magnetic resonance spectroscopy in full-term asphyxiated neonates. Pediatr Radiol 35:998-1005
13. Shanmugalingam S, Thornton JS, Iwata O et al (2006) Comparative prognostic utilities of early quantitative magnetic resonance imaging spin-spin relaxometry and proton magnetic resonance spectroscopy in neonatal encephalopathy. Pediatrics 118:1467-1477
14. Zhu W, Zhong W, Qi J, Yin P, Wang C, Chang L (2008) Proton magnetic resonance spectroscopy in neonates with hypoxicischemic injury and its prognostic value. Transl Res 152:225-232
15. Cady EB (1996) Metabolic concentrations and relaxation in perinatal cerebral hypoxic-ischemic injury. Neurochem Res 9:1043-1052
16. Boichot C, Walker PM, Durand C et al (2006) Term neonate prognosis after perinatal asphyxia: contributions of MR imaging, MR spectroscopy, relaxation times, and apparent diffusion coefficients. Radiology 239:839-848
17. Cheong JLY, Cady EB, Penrice J, Wyatt JS, Cox IJ, Robertson NJ (2006) Proton Mr spectroscopy in neonates with perinatal cerebral hypoxic-ischemic injury: metabolic peak-area ratios, relaxation times, and absolute concentrations. AJNR Am J Neuroradiol 27:1546-1554
18. Angeles DM, Ashwal S, Wycliffe ND et al (2007) Relationships between opioid therapy, tissue damaging procedures, and brain metabolites as measured by proton MRS in asphyxiated term neonates. Pediatr Res 61:614-621
19. Sarnat HB, Sarnat MS (1976) Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. Arch Neurol 33:696-705
20. Sijens PE, van den Bent MJ, Nowak PJ, van Dijk P, Oudkerk M (1997) 1H chemical shift imaging reveals loss of brain tumor choline signal after administration of Gd-contrast. Magn Reson Med 37:222-225
21. Verbruggen KT, Maurits NM, van Spronsen FJ, Brouwer OF, Sijens PE (2009) Quantitative multivoxel proton spectroscopy of the brain in developmental delay. J Magn Reson Imaging 30:716-721
22. Sijens PE, Oudkerk M, de Leeuw FE et al (1999) 1H chemical shift imaging of the human brain at age 60-90 years reveals metabolic differences between women and men. Magn Reson Med 42:24-31
23. Sijens PE, Mostert JP, Oudkerk M, De Keyser J (2006) 1H MR spectroscopy of the brain in multiple sclerosis subtypes with analysis of the metabolite concentrations in gray and white matter: initial findings. Eur Radiol 16:489-495
24. van Oostrom JC, Sijens PE, Roos RA, Leenders KL (2007) 1H magnetic resonance spectroscopy in preclinical Huntington disease. Brain Res 1168:67-71
25. McDowell B (2008) The gross motor function classification system-expanded and revised. Dev Med Child Neurol 50:725-730
26. Bayley N (1993) Bayley Scales of Infant Development, Second Edition. San Antonio, TX: The Psychological Corporation; www. psychocorp.com
27. Hempel MS (1993) The neurological examination for toddler-age [dissertation]. Groningen University Press, Groningen
28. Touwen BC (1968) Neurological examination of the young child. Ned Tijdschr Geneeskd 112:1112
29. Hanrahan JD, Cox IJ, Azzopardi J et al (1999) Relation between proton magnetic resonance spectroscopy within 18 hours of birth asphyxia and neurodevelopment at 1 year of age. Dev Med Child Neurol 41:76-82
30. L'Abee CL, de Vries LS, van der Grond JS, Groenendaal F (2005) Early diffusion-weighted MRI and 1H magnetic resonance spectroscopy in asphyxiated full-term neonates. Biol Neanate 88:306-312
31. Zariff MK, Astrakas LG, du Poussant TY, Plessis A, Zurakowski D, Tzika AA (2002) Prediction of adverse outcome with cerebral lactate level and apparent diffusion coefficient in infants with perinatal asphyxia. Radiology 225:859-870