Three types of striational antibodies in myasthenia gravis

Autoimmune Diseases

Volumn 1, Issue 1, 2011, Pages

  Suzuki, Shigeaki ^a   Utsugisawa, Kimiaki ^b   Nagane, Yuriko ^b   Suzuki, Norihiro ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Hanamaki General Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; AUTOANTIBODY; CALCINEURIN INHIBITOR; CHOLINERGIC RECEPTOR; CONNECTIN; CORTICOSTEROID; CYCLOSPORIN; EPITOPE; IMMUNOSUPPRESSIVE AGENT; POTASSIUM CHANNEL KV1.4; PREDNISOLONE; PREDNISONE; RYANODINE RECEPTOR; STRIATIONAL ANTIBODY; TACROLIMUS; UNCLASSIFIED DRUG;

ANTIBODY DETECTION; CHEMICAL STRUCTURE; CLINICAL FEATURE; DISEASE SEVERITY; DRUG DOSE REDUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOBLOTTING; IMMUNOPATHOGENESIS; IMMUNOTHERAPY; MYASTHENIA GRAVIS; MYOCARDITIS; NEUROMUSCULAR SYNAPSE; PRIORITY JOURNAL; REVIEW; THYMOMA; TREATMENT PLANNING; UNSPECIFIED SIDE EFFECT;

EID: 84861460473     PISSN: None     EISSN: 20900430     Source Type: Journal    
DOI: 10.4061/2011/740583     Document Type: Review

References (51)

1. Meriggioli M. N., Sanders D. B., Autoimmune myasthenia gravis: emerging clinical and biological heterogeneity The Lancet Neurology 2009 8 5 475 490
2. Williams C. L., Lennon V. A., Thymic B lymphocyte clones from patients with myasthenia gravis secrete monoclonal striational autoantibodies reacting with myosin, actinin, or actin Journal of Experimental Medicine 1986 164 4 1043 1059 (Pubitemid 16031605)
3. Yamamoto T., Sato T., Sugita H., Antifilamin, antivinculin, and antitropomyosin antibodies in myasthenia gravis Neurology 1987 37 8 1329 1333
4. Ohta M., Ohta K., Itoh N., Kurobe M., Hayashi K., Nishitani H., Anti-skeletal muscle antibodies in the sera from myasthenic patients with thymoma: identification of anti-myosin, actomysin, actin, and -actinin antibodies by a solid-phase radioimmunoassay and a Western blotting analysis Clinica Chimica Acta 1990 187 3 255 264 (Pubitemid 20100970)
5. Aarli J. A., Lefvert A. K., Tonder O., Thymoma-specific antibodies in sera from patients with myasthenia gravis demonstrated by indirect haemagglutination Journal of Neuroimmunology 1981 1 4 421 427 (Pubitemid 12134234)
6. Labeit S., Barlow D. P., Gautel M., Gibson T., Holt J., Hsieh C. L., Francke U., Leonard K., Wardale J., Whiting A., Trinick J., A regular pattern of two types of 100-residue motif in the sequence of titin Nature 1990 345 6272 273 276
7. Aarli J. A., Stefansson K., Marton L. S. G., Wollmann R. L., Patients with myasthenia gravis and thymoma have in their sera IgG autoantibodies against titin Clinical and Experimental Immunology 1990 82 2 284 288 (Pubitemid 20359537)
8. Romi F., Skeie G. O., Gilhus N. E., Aarli J. A., Striational antibodies in myasthenia gravis: reactivity and possible clinical significance Archives of Neurology 2005 62 3 442 446 (Pubitemid 40349480)
9. Gautel M., Lakey A., Barlow D. P., Holmes Z., Scales S., Leonard K., Labeit S., Mygland A., Gilhus N. E., Aarli J. A., Titin antibodies in myasthenia gravis: identification of a major immunogenic region of titin Neurology 1993 43 8 1581 1585 (Pubitemid 23230548)
10. Lbke E., Freiburg A., Skeie G. O., Kolmerer B., Labeit S., Aarli J. A., Gilhus N. E., Wollmann R., Wussling M., Regg J. C., Linke W. A., Striational autoantibodies in myasthenia gravis patients recognize I- band titin epitopes Journal of Neuroimmunology 1998 81 1-2 98 108 (Pubitemid 28248189)
11. Mygland A., Tysnes O. B., Matre R., Volpe P., Aarli J. A., Gilhus N. E., Ryanodine receptor autoantibodies in myasthenia gravis patients with a thymoma Annals of Neurology 1992 32 4 589 591
12. Mygland A., Tysnes O. B., Matre R., Aarli J. A., Gilhus N. E., Anti-cardiac ryanodine receptor antibodies in thymoma-associated myasthenia gravis Autoimmunity 1994 17 4 327 331 (Pubitemid 24238339)
13. Suzuki S., Satoh T., Yasuoka H., Hamaguchi Y., Tanaka K., Kawakami Y., Suzuki N., Kuwana M., Novel autoantibodies to a voltage-gated potassium channel KV1.4 in a severe form of myasthenia gravis Journal of Neuroimmunology 2005 170 1-2 141 149 (Pubitemid 41740915)
14. Yamamoto A. M., Gajdos P., Eymard B., Tranchant C., Warter J. M., Gomez L., Bourquin C., Bach J. F., Garchon H. J., Anti-titin antibodies in myasthenia gravis: tight association with thymoma and heterogeneity of nonthymoma patients Archives of Neurology 2001 58 6 885 890 (Pubitemid 32537462)
15. Giraud M., Beaurain G., Yamamoto A. M., Eymard B., Tranchant C., Gajdos P., Garchon H. J., Linkage of HLA to myasthenia gravis and genetic heterogeneity depending on anti-titin antibodies Neurology 2001 57 9 1555 1560 (Pubitemid 33055467)
16. Buckley C., Newsom-Davis J., Willcox N., Vincent A., Do titin and cytokine antibodies in MG patients predict thymoma or thymoma recurrence? Neurology 2001 57 9 1579 1582 (Pubitemid 33055473)
17. Chen X. J., Qiao J., Xiao B. G., Lu C. Z., The significance of titin antibodies in myasthenia gravis: correlation with thymoma and severity of myasthenia gravis Journal of Neurology 2004 251 8 1006 1011 (Pubitemid 39119320)
18. Romi F., Aarli J. A., Gilhus N. E., Myasthenia gravis patients with ryanodine receptor antibodies have distinctive clinical features European Journal of Neurology 2007 14 6 617 620 (Pubitemid 46849058)
19. Suzuki S., Utsugisawa K., Nagane Y., Satoh T., Terayama Y., Suzuki N., Kuwana M., Classification of myasthenia gravis based on autoantibody status Archives of Neurology 2007 64 8 1121 1124 (Pubitemid 47258071)
20. Suzuki S., Utsugisawa K., Nagane Y., Satoh T., Kuwana M., Suzuki N., Clinical and immunological differences between early and late-onset myasthenia gravis in Japan Journal of Neuroimmunology 2011 230 148 152
21. Aarli J. A., Myasthenia gravis in the elderly: is it different? Annals of the New York Academy of Sciences 2008 1132 238 243 (Pubitemid 351841380)
22. Romi F., Kristoffersen E. K., Aarli J. A., Gilhus N. E., The role of complement in myasthenia gravis: serological evidence of complement consumption in vivo Journal of Neuroimmunology 2005 158 1-2 191 194 (Pubitemid 39626086)
23. Skeie G. O., Bentsen P. T., Freiburg A., Aarli J. A., Gilhus N. E., Cell-mediated immune response against titin in myasthenia gravis: evidence for the involvement of Th1 and Th2 cells Scandinavian Journal of Immunology 1998 47 1 76 81 (Pubitemid 28057355)
24. Romi F., Skeie G. O., Vedeler C., Aarli J. A., Zorzato F., Gilhus N. E., Complement activation by titin and ryanodine receptor autoantibodies in myasthenia gravis A study of IgG subclasses and clinical correlations Journal of Neuroimmunology 2000 111 1-2 169 176
25. Somnier F. E., Skeie G. O., Aarli J. A., Trojaborg W., EMG evidence of myopathy and the occurrence of titin autoantibodies in patients with myasthenia gravis European Journal of Neurology 1999 6 5 555 563 (Pubitemid 30028810)
26. Skeie G. O., Mygland A., Treves S., Gilhus N. E., Aarli J. A., Zorzato F., Ryanodine receptor antibodies in myasthenia gravis: epitope mapping and effect on calcium release in vitro Muscle and Nerve 2003 27 1 81 89 (Pubitemid 36083448)
27. Nakata M., Kuwabara S., Kawaguchi N., Takahashi H., Misawa S., Kanai K., Tamura N., Sawai S., Motomura M., Shiraishi H., Takamori M., Maruta T., Yoshikawa H., Hattori T., Is excitation-contraction coupling impaired in myasthenia gravis? Clinical Neurophysiology 2007 118 5 1144 1148 (Pubitemid 46518282)
28. Tsuda E., Imai T., Hozuki T., Yamauchi R., Saitoh M., Hisahara S., Yoshikawa H., Motomura M., Shimohama S., Correlation of bite force with excitation-contraction coupling time of the masseter in myasthenia gravis Clinical Neurophysiology 2010 121 7 1051 1058
29. Imai T., Tsuda E., Toyoshima T., Yoshikawa H., Motomura M., Shimohama S., Anti-ryanodine receptor-positive acetylcholine receptor-negative myasthenia gravis: evidence of impaired excitation-contraction coupling Muscle and Nerve 2011 43 2 294 295
30. Takamori M., Autoantibodies against TRPC3 and ryanodine receptor in myasthenia gravis Journal of Neuroimmunology 2008 200 1-2 142 144
31. Maruta T., Yoshikawa H., Fukasawa S., Umeshita S., Inaoka Y., Edahiro S., Kado H., Motozaki Y., Iwasa K., Yamada M., Autoantibody to dihydropyridine receptor in myasthenia gravis Journal of Neuroimmunology 2009 208 1-2 125 129
32. Tan K. M., Lennon V. A., Klein C. J., Boeve B. F., Pittock S. J., Clinical spectrum of voltage-gated potassium channel autoimmunity Neurology 2008 70 20 1883 1890 (Pubitemid 351684641)
33. Lai M., Huijbers M. G. M., Lancaster E., Graus F., Bataller L., Balice-Gordon R., Cowell J. K., Dalmau J., Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series The Lancet Neurology 2010 9 8 776 785
34. Evoli A., Minisci C., Di Schino C., Marsili F., Punzi C., Batocchi A. P., Tonali P. A., Doglietto G. B., Granone P., Trodella L., Cassano A., Lauriola L., Thymoma in patients with MG: characteristics and long-term outcome Neurology 2002 59 12 1844 1850 (Pubitemid 36076553)
35. Mygland A., Kuwajima G., Mikoshiba K., Tysnes O. B., Aarli J. A., Gilhus N. E., Thymomas express epitopes shared by the ryanodine receptor Journal of Neuroimmunology 1995 62 1 79 83
36. Marx A., Wilisch A., Schultz A., Greiner A., Magi B., Pallini V., Schalke B., Toyka K., Nix W., Kirchner T., Mller-Hermelink H. -K., Expression of neurofilaments and of a titin epitope in thymic epithelial tumors. Implications for the pathogenesis of Myasthenia gravis American Journal of Pathology 1996 148 6 1839 1850
37. Kusner L. L., Mygland A., Kaminski H. J., Ryanodine receptor gene expression thymomas Muscle and Nerve 1998 21 10 1299 1303 (Pubitemid 28406712)
38. Romi F., Bo L., Skeie G. O., Myking A., Aarli J. A., Gilhus N. E., Titin and ryanodine receptor epitopes are expressed in cortical thymoma along with costimulatory molecules Journal of Neuroimmunology 2002 128 1-2 82 89 (Pubitemid 34722367)
39. Williams C. L., Hay J. E., Huiatt T. W., Lennon V. A., Paraneoplastic IgG striational autoantibodies produced by clonal thymic B cells and in serum of patients with myasthenia gravis and thymoma react with titin Laboratory Investigation 1992 66 3 331 336
40. Takamori M., Motomura M., Kawaguchi N., Nemoto Y., Hattori T., Yoshikawa H., Otsuka K., Anti-ryanodine receptor antibodies and FK506 in myasthenia gravis Neurology 2004 62 10 1894 1896 (Pubitemid 38661763)
41. Iwasa K., Komai K., Takamori M., Spontaneous thymoma rat as a model for myasthenic weakness caused by anti-ryanodine receptor antibodies Muscle and Nerve 1998 21 12 1655 1660 (Pubitemid 28545694)
42. Mygland A., Aarli J. A., Matre R., Gilhus N. E., Ryanodine receptor antibodies related to severity of thymoma associated myasthenia gravis Journal of Neurology Neurosurgery and Psychiatry 1994 57 7 843 846 (Pubitemid 24214970)
43. Romi F., Gilhus N. E., Varhaug J. E., Myking A., Aarli J. A., Disease severity and outcome in thymoma myasthenia gravis: a long-term observation study European Journal of Neurology 2003 10 6 701 706 (Pubitemid 38030881)
44. Romi F., Skeie G. O., Aarli J. A., Gilhus N. E., The severity of myasthenia gravis correlates with the serum concentration of titin and ryanodine receptor antibodies Archives of Neurology 2000 57 11 1596 1600
45. Mygland A., Vincent A., Autoantibodies in thymoma-associated myasthenia gravis with myositis or neuromyotonia Archives of Neurology 2000 57 4 527 531 (Pubitemid 30212127)
46. Suzuki S., Utsugisawa K., Yoshikawa H., Motomura M., Matsubara S., Yokoyama K., Nagane Y., Maruta T., Satoh T., Sato H., Kuwana M., Suzuki N., Autoimmune targets of heart and skeletal muscles in myasthenia gravis Archives of Neurology 2009 66 11 1334 1338
47. Aarli J. A., Herzmyasthenie: myasthenia of the heart Archives of Neurology 2009 66 11 1322 1323
48. Sato H., Iwasaki E., Nogawa S., Suzuki S., Amano T., Fukuuchi Y., Shimoda M., Okada Y., A patient with giant cell myocarditis and myositis associated with thymoma and myasthenia gravis Clinical Neurology 2003 43 8 496 499 (Pubitemid 37433030)
49. Tsugawa J., Tsuboi Y., Inoue H., Suzuki S., Yamada T., Recurrent syncope due to sick sinus syndrome in a patient with myasthenia gravis associated with thymoma Clinical Neurology 2011 51 1 32 34
50. Nakamura K., Katayama Y., Kusano K. F., Haraoka K., Tani Y., Nagase S., Morita H., Miura D., Fujimoto Y., Furukawa T., Ueda K., Aizawa Y., Kimura A., Kurachi Y., Ohe T., Anti-KCNH2 Antibody-Induced Long QT Syndrome. Novel Acquired Form of Long QT Syndrome Journal of the American College of Cardiology 2007 50 18 1808 1809 (Pubitemid 47600584)
51. Nagane Y., Suzuki S., Suzuki N., Utsugisawa K., Factors associated with response to calcineurin inhibitors in myasthenia gravis Muscle and Nerve 2010 41 2 212 218