Autoantibody to dihydropyridine receptor in myasthenia gravis

Journal of Neuroimmunology

Volumn 208, Issue 1-2, 2009, Pages 125-129

  Maruta, Takahiro ^a,b   Yoshikawa, Hiroaki ^a   Fukasawa, Shuichi ^a   Umeshita, Sho ^a   Inaoka, Yoshihiro ^a   Edahiro, Shigeki ^a   Kado, Hirotsugu ^a,b   Motozaki, Yuko ^a   Iwasa, Kazuo ^a   Yamada, Masahito ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b Keiju Medical Center   (Japan)

Author keywords

Autoantibody; Dihydropyridine receptor; Excitation contraction coupling; Myasthenia gravis; Ryanodine receptor; Thymoma

Indexed keywords

1,4 DIHYDROPYRIDINE RECEPTOR; AUTOANTIBODY; CHOLINERGIC RECEPTOR; RECEPTOR ANTIBODY; RYANODINE RECEPTOR; TUMOR MARKER;

ADULT; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; EXCITATION CONTRACTION COUPLING; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MYASTHENIA GRAVIS; PRIORITY JOURNAL; THYMOMA;

AUTOANTIBODIES; BIOLOGICAL MARKERS; CALCIUM CHANNELS, L-TYPE; FEMALE; HUMANS; MALE; MIDDLE AGED; MYASTHENIA GRAVIS;

EID: 62549113408     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2009.01.001     Document Type: Article

References (20)

1. Bellinger A.M., Mongillo M., and Marks A.R. Stressed out: the skeletal muscle ryanodine receptor as a target of stress. J. Clin. Invest. 118 (2008) 445-453
2. Conti-Fine B.M., Milani M., and Kaminski H.J. Myasthenia gravis: past, present, and future. J. Clin. Invest. 116 (2006) 2843-2854
3. Dwyer D.S., Bradley R.J., Urquhart C.K., and Kearney J.F. An enzyme-linked immunoabsorbent assay for measuring antibodies against muscle acetylcholine receptor. J. Immunol. Methods 57 (1983) 111-119
4. Grabner M., Dirksen R.T., and Beam K.G. Tagging with green fluorescent protein reveals a distinct subcellular distribution of L-type and non-L-type Ca2+ channels expressed in dysgenic myotubes. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 1903-1908
5. Inui M., Saito A., and Fleischer S. Purification of the ryanodine receptor and identity with feet structures of junctional terminal cisternae of sarcoplasmic reticulum from fast skeletal muscle. J. Biol. Chem. 262 (1987) 1740-1747
6. Iwasa K. Striational autoantibodies in myasthenia gravis mainly react with ryanodine receptor. Muscle Nerve 20 (1997) 753-756
7. Lindstrom J.M., Seybold M.E., Lennon V.A., Whittingham S., and Duane D.D. Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic value. Neurology 26 (1976) 1054-1059
8. Morton M.E., and Froehner S.C. Monoclonal antibody identifies a 200-kDa subunit of the dihydropyridine-sensitive calcium channel. J. Biol. Chem. 262 (1987) 11904-11907
9. Morton M.E., Caffrey J.M., Brown A.M., and Froehner S.C. Monoclonal antibody to the alpha 1-subunit of the dihydropyridine-binding complex inhibits calcium currents in BC3H1 myocytes. J. Biol. Chem. 263 (1988) 613-616
10. Motomura M., Lang B., Johnston I., Palace J., Vincent A., and Newsom-Davis J. Incidence of serum anti-P/O-type and anti-N-type calcium channel autoantibodies in the Lambert-Eaton myasthenic syndrome. J. Neurol. Sci. 147 (1997) 35-42
11. Mygland A., Tysnes O.B., Matre R., Volpe P., Aarli J.A., and Gilhus N.E. Ryanodine receptor autoantibodies in myasthenia gravis patients with a thymoma. Ann. Neurol. 32 (1992) 589-591
12. Noda M., Furutani Y., Takahashi H., Toyosato M., Tanabe T., Shimizu S., Kikyotani S., Kayano T., Hirose T., Inayama S., and Numa S. Cloning and sequence analysis of calf cDNA and human genomic DNA encoding alpha-subunit precursor of muscle acetylcholine receptor. Nature 305 (1983) 818-823
13. Pagala M., Nandakumar N.V., Venkatachari S.A., Ravindran K., Amaladevi B., Namba T., and Grob D. Mechanisms of fatigue in normal intercostal muscle and muscle from patients with myasthenia gravis. Muscle Nerve 16 (1993) 911-921
14. Perez-Reyes E., Castellano A., Kim H.S., Bertrand P., Baggstrom E., Lacerda A.E., Wei X.Y., and Birnbaumer L. Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel. J. Biol. Chem. 267 (1992) 1792-1797
15. Saito A., Seiler S., Chu A., and Fleischer S. Preparation and morphology of sarcoplasmic reticulum terminal cisternae from rabbit skeletal muscle. J. Cell Biol. 99 (1984) 875-885
16. Skeie G.O., Aarli J.A., and Gilhus N.E. Titin and ryanodine receptor antibodies in myasthenia gravis. Acta Neurol. Scand. Suppl. 183 (2006) 19-23
17. Takamori M., Motomura M., Kawaguchi N., Nemoto Y., Hattori T., Yoshikawa H., and Otsuka K. Anti-ryanodine receptor antibodies and FK506 in myasthenia gravis. Neurology 62 (2004) 1894-1896
18. Takeshima H., Iino M., Takekura H., Nishi M., Kuno J., Minowa O., Takano H., and Noda T. Excitation-contraction uncoupling and muscular degeneration in mice lacking functional skeletal muscle ryanodine-receptor gene. Nature 369 (1994) 556-559
19. Tanabe T., Takeshima H., Mikami A., Flockerzi V., Takahashi H., Kangawa K., Kojima M., Matsuo H., Hirose T., and Numa S. Primary structure of the receptor for calcium channel blockers from skeletal muscle. Nature 328 (1987) 313-318
20. Zorzato F., Fujii J., Otsu K., Phillips M., Green N.M., Lai F.A., Meissner G., and MacLennan D.H. Molecular cloning of cDNA encoding human and rabbit forms of the Ca2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum. J. Biol. Chem. 265 (1990) 2244-2256