메뉴 건너뛰기




Volumn 7, Issue 5, 2012, Pages

Propentofylline targets TROY, a novel microglial signaling pathway

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN; PROPENTOFYLLINE; TUMOR NECROSIS FACTOR RECEPTOR OF MOUSE EMBRYO; UNCLASSIFIED DRUG; FOCAL ADHESION KINASE 2; NEUROPEPTIDE; PTK2B PROTEIN, MOUSE; RAC PROTEIN; RAC1 PROTEIN, MOUSE; SMALL INTERFERING RNA; TNFRSF19 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR RECEPTOR; XANTHINE DERIVATIVE;

EID: 84861395022     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037955     Document Type: Article
Times cited : (22)

References (31)
  • 1
    • 14744270886 scopus 로고    scopus 로고
    • Chemotherapy for brain tumors-a new beginning
    • DeAngelis LM, (2005) Chemotherapy for brain tumors-a new beginning. N Engl J Med 352: 1036-1038.
    • (2005) N Engl J Med , vol.352 , pp. 1036-1038
    • DeAngelis, L.M.1
  • 2
    • 20344407807 scopus 로고    scopus 로고
    • Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas
    • Ohgaki H, Kleihues P, (2005) Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas. J Neuropathol Exp Neurol 64: 479-489.
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 479-489
    • Ohgaki, H.1    Kleihues, P.2
  • 3
    • 0029781336 scopus 로고    scopus 로고
    • Distribution and characterization of microglia/macrophages in human brain tumors
    • Roggendorf W, Strupp S, Paulus W, (1996) Distribution and characterization of microglia/macrophages in human brain tumors. Acta Neuropathol 92: 288-293.
    • (1996) Acta Neuropathol , vol.92 , pp. 288-293
    • Roggendorf, W.1    Strupp, S.2    Paulus, W.3
  • 4
    • 72449154567 scopus 로고    scopus 로고
    • The role of microglia in central nervous system immunity and glioma immunology
    • Yang I, Han SJ, Kaur G, Crane C, Parsa AT, (2010) The role of microglia in central nervous system immunity and glioma immunology. J Clin Neurosci 17: 6-10.
    • (2010) J Clin Neurosci , vol.17 , pp. 6-10
    • Yang, I.1    Han, S.J.2    Kaur, G.3    Crane, C.4    Parsa, A.T.5
  • 5
    • 68649120407 scopus 로고    scopus 로고
    • Recurrence pattern in glioblastoma multiforme patients treated with anti-angiogenic chemotherapy
    • Tuettenberg J, Grobholz R, Seiz M, Brockmann MA, Lohr F, et al. (2009) Recurrence pattern in glioblastoma multiforme patients treated with anti-angiogenic chemotherapy. J Cancer Res Clin Oncol 135: 1239-1244.
    • (2009) J Cancer Res Clin Oncol , vol.135 , pp. 1239-1244
    • Tuettenberg, J.1    Grobholz, R.2    Seiz, M.3    Brockmann, M.A.4    Lohr, F.5
  • 6
    • 80052069274 scopus 로고    scopus 로고
    • Characteristics of the alternative phenotype of microglia/macrophages and its modulation in experimental gliomas
    • Gabrusiewicz KE-MA, Lipko M, Sielska M, Frankowska M, Kaminska B, (2011) Characteristics of the alternative phenotype of microglia/macrophages and its modulation in experimental gliomas. PLoS One 6.
    • (2011) PLoS One , vol.6
    • Gabrusiewicz, K.E.-M.A.1    Lipko, M.2    Sielska, M.3    Frankowska, M.4    Kaminska, B.5
  • 7
    • 78049270536 scopus 로고    scopus 로고
    • Glioma cancer stem cells induce immunosuppressive macrophages/microglia
    • Wu A, Wei J, Kong LY, Wang Y, Priebe W, et al. (2010) Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro Oncol 12: 1113-1125.
    • (2010) Neuro Oncol , vol.12 , pp. 1113-1125
    • Wu, A.1    Wei, J.2    Kong, L.Y.3    Wang, Y.4    Priebe, W.5
  • 9
    • 84861404743 scopus 로고    scopus 로고
    • Propentofylline decreases tumor growth in a rodent model of glioblastoma multiforme by a direct mechanism on microglia
    • Jacobs VL, Landry RP, Liu Y, Romero-Sandoval EA, De Leo JA, (2011) Propentofylline decreases tumor growth in a rodent model of glioblastoma multiforme by a direct mechanism on microglia. Neuro Oncol.
    • (2011) Neuro Oncol
    • Jacobs, V.L.1    Landry, R.P.2    Liu, Y.3    Romero-Sandoval, E.A.4    De Leo, J.A.5
  • 10
    • 35348866157 scopus 로고    scopus 로고
    • Integrins: molecular determinants of glioma invasion
    • D'Abaco GM, Kaye AH, (2007) Integrins: molecular determinants of glioma invasion. J Clin Neurosci 14: 1041-1048.
    • (2007) J Clin Neurosci , vol.14 , pp. 1041-1048
    • D'Abaco, G.M.1    Kaye, A.H.2
  • 11
    • 0031745571 scopus 로고    scopus 로고
    • Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins
    • Aplin AE, Howe A, Alahari SK, Juliano RL, (1998) Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins. Pharmacol Rev 50: 197-263.
    • (1998) Pharmacol Rev , vol.50 , pp. 197-263
    • Aplin, A.E.1    Howe, A.2    Alahari, S.K.3    Juliano, R.L.4
  • 12
    • 0034766198 scopus 로고    scopus 로고
    • Glioma cell motility is associated with reduced transcription of proapoptotic and proliferation genes: a cDNA microarray analysis
    • Mariani L, Beaudry C, McDonough WS, Hoelzinger DB, Demuth T, et al. (2001) Glioma cell motility is associated with reduced transcription of proapoptotic and proliferation genes: a cDNA microarray analysis. J Neurooncol 53: 161-176.
    • (2001) J Neurooncol , vol.53 , pp. 161-176
    • Mariani, L.1    Beaudry, C.2    McDonough, W.S.3    Hoelzinger, D.B.4    Demuth, T.5
  • 13
    • 13444294190 scopus 로고    scopus 로고
    • Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets
    • Hoelzinger DB, Mariani L, Weis J, Woyke T, Berens TJ, et al. (2005) Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets. Neoplasia 7: 7-16.
    • (2005) Neoplasia , vol.7 , pp. 7-16
    • Hoelzinger, D.B.1    Mariani, L.2    Weis, J.3    Woyke, T.4    Berens, T.J.5
  • 14
    • 77956615515 scopus 로고    scopus 로고
    • Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways
    • Veroni C, Gabriele L, Canini I, Castiello L, Coccia E, et al. (2010) Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways. Mol Cell Neurosci 45: 234-244.
    • (2010) Mol Cell Neurosci , vol.45 , pp. 234-244
    • Veroni, C.1    Gabriele, L.2    Canini, I.3    Castiello, L.4    Coccia, E.5
  • 15
    • 78649640148 scopus 로고    scopus 로고
    • TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling
    • Paulino VM, Yang Z, Kloss J, Ennis MJ, Armstrong BA, et al. (2010) TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling. Mol Cancer Res 8: 1558-1567.
    • (2010) Mol Cancer Res , vol.8 , pp. 1558-1567
    • Paulino, V.M.1    Yang, Z.2    Kloss, J.3    Ennis, M.J.4    Armstrong, B.A.5
  • 16
    • 13244255374 scopus 로고    scopus 로고
    • A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors
    • Park JB, Yiu G, Kaneko S, Wang J, Chang J, et al. (2005) A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors. Neuron 45: 345-351.
    • (2005) Neuron , vol.45 , pp. 345-351
    • Park, J.B.1    Yiu, G.2    Kaneko, S.3    Wang, J.4    Chang, J.5
  • 17
    • 19944432743 scopus 로고    scopus 로고
    • TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration
    • Shao Z, Browning JL, Lee X, Scott ML, Shulga-Morskaya S, et al. (2005) TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration. Neuron 45: 353-359.
    • (2005) Neuron , vol.45 , pp. 353-359
    • Shao, Z.1    Browning, J.L.2    Lee, X.3    Scott, M.L.4    Shulga-Morskaya, S.5
  • 18
    • 77952000649 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal (stromal) stem cells through canonical Wnt signaling and C/EBP
    • Qiu W, Hu Y, Andersen TE, Jafari A, Li N, et al. (2010) Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal (stromal) stem cells through canonical Wnt signaling and C/EBP. J Biol Chem 285: 14438-14449.
    • (2010) J Biol Chem , vol.285 , pp. 14438-14449
    • Qiu, W.1    Hu, Y.2    Andersen, T.E.3    Jafari, A.4    Li, N.5
  • 19
    • 77957579033 scopus 로고    scopus 로고
    • Propentofylline: glial modulation, neuroprotection, and alleviation of chronic pain
    • Sweitzer S, De Leo J, (2011) Propentofylline: glial modulation, neuroprotection, and alleviation of chronic pain. Handb Exp Pharmacol pp. 235-250.
    • (2011) Handb Exp Pharmacol , pp. 235-250
    • Sweitzer, S.1    de Leo, J.2
  • 20
    • 0021810477 scopus 로고
    • In vitro and in vivo inhibitory effects of propentofylline on cyclic AMP phosphodiesterase activity
    • Nagata K, Ogawa T, Omosu M, Fujimoto K, Hayashi S, (1985) In vitro and in vivo inhibitory effects of propentofylline on cyclic AMP phosphodiesterase activity. Arzneimittelforschung 35: 1034-1036.
    • (1985) Arzneimittelforschung , vol.35 , pp. 1034-1036
    • Nagata, K.1    Ogawa, T.2    Omosu, M.3    Fujimoto, K.4    Hayashi, S.5
  • 21
    • 0022527550 scopus 로고
    • The xanthine derivative 1-(5′-oxohexyl)-3-methyl-7-propyl xanthine (HWA 285) enhances the actions of adenosine
    • Fredholm BB, Lindstrom K, (1986) The xanthine derivative 1-(5′-oxohexyl)-3-methyl-7-propyl xanthine (HWA 285) enhances the actions of adenosine. Acta Pharmacol Toxicol (Copenh) 58: 187-192.
    • (1986) Acta Pharmacol Toxicol (Copenh) , vol.58 , pp. 187-192
    • Fredholm, B.B.1    Lindstrom, K.2
  • 22
    • 0028630920 scopus 로고
    • A rat glioma model, CNS-1, with invasive characteristics similar to those of human gliomas: a comparison to 9 L gliosarcoma
    • Kruse CA, Molleston MC, Parks EP, Schiltz PM, Kleinschmidt-DeMasters BK, et al. (1994) A rat glioma model, CNS-1, with invasive characteristics similar to those of human gliomas: a comparison to 9 L gliosarcoma. J Neurooncol 22: 191-200.
    • (1994) J Neurooncol , vol.22 , pp. 191-200
    • Kruse, C.A.1    Molleston, M.C.2    Parks, E.P.3    Schiltz, P.M.4    Kleinschmidt-DeMasters, B.K.5
  • 23
    • 36249012543 scopus 로고    scopus 로고
    • Minocycline decreases in vitro microglial motility, beta1-integrin, and Kv1.3 channel expression
    • Nutile-McMenemy N, Elfenbein A, Deleo JA, (2007) Minocycline decreases in vitro microglial motility, beta1-integrin, and Kv1.3 channel expression. J Neurochem 103: 2035-2046.
    • (2007) J Neurochem , vol.103 , pp. 2035-2046
    • Nutile-McMenemy, N.1    Elfenbein, A.2    Deleo, J.A.3
  • 24
    • 53149124406 scopus 로고    scopus 로고
    • Differential migration, LPS-induced cytokine, chemokine, and NO expression in immortalized BV-2 and HAPI cell lines and primary microglial cultures
    • Horvath RJ, Nutile-McMenemy N, Alkaitis MS, Deleo JA, (2008) Differential migration, LPS-induced cytokine, chemokine, and NO expression in immortalized BV-2 and HAPI cell lines and primary microglial cultures. J Neurochem 107: 557-569.
    • (2008) J Neurochem , vol.107 , pp. 557-569
    • Horvath, R.J.1    Nutile-McMenemy, N.2    Alkaitis, M.S.3    Deleo, J.A.4
  • 25
    • 33646950387 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor and its receptor ret is a novel ligand-receptor complex critical for survival response during podocyte injury
    • Tsui CC, Shankland SJ, Pierchala BA, (2006) Glial cell line-derived neurotrophic factor and its receptor ret is a novel ligand-receptor complex critical for survival response during podocyte injury. J Am Soc Nephrol 17: 1543-1552.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1543-1552
    • Tsui, C.C.1    Shankland, S.J.2    Pierchala, B.A.3
  • 26
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW, (2004) Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 4: 71-78.
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 27
    • 82155181745 scopus 로고    scopus 로고
    • A forward loop between glioma and microglia: Glioma-derived extracellular matrix-activated microglia secrete IL-18 to enhance the migration of glioma cells
    • Yeh WL, Lu DY, Liou HC, Fu WM, (2012) A forward loop between glioma and microglia: Glioma-derived extracellular matrix-activated microglia secrete IL-18 to enhance the migration of glioma cells. J Cell Physiol 227: 558-568.
    • (2012) J Cell Physiol , vol.227 , pp. 558-568
    • Yeh, W.L.1    Lu, D.Y.2    Liou, H.C.3    Fu, W.M.4
  • 28
    • 80855133497 scopus 로고    scopus 로고
    • Recurrent glioblastoma: a fresh look at current therapies and emerging novel approaches
    • Gilbert MR, (2011) Recurrent glioblastoma: a fresh look at current therapies and emerging novel approaches. Semin Oncol 38 (Suppl 4): S21-33.
    • (2011) Semin Oncol , vol.38 , Issue.SUPPL. 4
    • Gilbert, M.R.1
  • 29
    • 0034686080 scopus 로고    scopus 로고
    • TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death
    • Eby MT, Jasmin A, Kumar A, Sharma K, Chaudhary PM, (2000) TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death. J Biol Chem 275: 15336-15342.
    • (2000) J Biol Chem , vol.275 , pp. 15336-15342
    • Eby, M.T.1    Jasmin, A.2    Kumar, A.3    Sharma, K.4    Chaudhary, P.M.5
  • 30
    • 0032734626 scopus 로고    scopus 로고
    • Characterization of TNFRSF19, a novel member of the tumor necrosis factor receptor superfamily
    • Hu S, Tamada K, Ni J, Vincenz C, Chen L, (1999) Characterization of TNFRSF19, a novel member of the tumor necrosis factor receptor superfamily. Genomics 62: 103-107.
    • (1999) Genomics , vol.62 , pp. 103-107
    • Hu, S.1    Tamada, K.2    Ni, J.3    Vincenz, C.4    Chen, L.5
  • 31
    • 49049098529 scopus 로고    scopus 로고
    • TROY, a novel member of the tumor necrosis factor receptor superfamily in the central nervous system
    • Morikawa Y, Hisaoka T, Kitamura T, Senba E, (2008) TROY, a novel member of the tumor necrosis factor receptor superfamily in the central nervous system. Ann N Y Acad Sci 1126: A1-10.
    • (2008) Ann N Y Acad Sci , vol.1126
    • Morikawa, Y.1    Hisaoka, T.2    Kitamura, T.3    Senba, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.