-
1
-
-
69349097813
-
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer
-
Amundadottir, L., Kraft, P., Stolzenberg-Solomon, R.Z., Fuchs, C.S., Petersen, G.M., and Arslan, A.A. (2009). Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet 41, 986-990.
-
(2009)
Nat Genet
, vol.41
, pp. 986-990
-
-
Amundadottir, L.1
Kraft, P.2
Stolzenberg-Solomon, R.Z.3
Fuchs, C.S.4
Petersen, G.M.5
Arslan, A.A.6
-
2
-
-
0037244012
-
Negative regulation of T cell receptor-lipid raft interaction by cytotoxic T lymphocyte-associated antigen 4
-
DOI 10.1084/jem.20021646
-
Chikuma, S., Imboden, J.B., and Bluestone, J.A. (2003). Negative regulation of T cell receptor-lipid raft interaction by cytotoxic T lymphocyte-associated antigen 4. J Exp Med 197, 129-135. (Pubitemid 36110264)
-
(2003)
Journal of Experimental Medicine
, vol.197
, Issue.1
, pp. 129-135
-
-
Chikuma, S.1
Imboden, J.B.2
Bluestone, J.A.3
-
3
-
-
35148814410
-
Dynamics of the immune reaction to pancreatic cancer from inception to invasion
-
DOI 10.1158/0008-5472.CAN-07-0175
-
Clark, C.E., Hingorani, S.R., Mick, R., Combs, C., Tuveson, D.A., and Vonderheide, R.H. (2007). Dynamics of the immune reaction to pancreatic cancer from inception to invasion. Cancer Res 67, 9518-9527. (Pubitemid 47535942)
-
(2007)
Cancer Research
, vol.67
, Issue.19
, pp. 9518-9527
-
-
Clark, C.E.1
Hingorani, S.R.2
Mick, R.3
Combs, C.4
Tuveson, D.A.5
Vonderheide, R.H.6
-
4
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
Dong, H., Strome, S.E., Salomao, D.R., Tamura, H., Hirano, F., Flies, D.B., Roche, P.C., Lu, J., Zhu, G., Tamada, K., Lennon, V.A., Celis, E., and Chen, L. (2002). Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 8, 793-800.
-
(2002)
Nat Med
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
Roche, P.C.7
Lu, J.8
Zhu, G.9
Tamada, K.10
Lennon, V.A.11
Celis, E.12
Chen, L.13
-
5
-
-
0036301503
-
CTLA-4: New insights into its biological function and use in tumor immunotherapy
-
DOI 10.1038/ni0702-611
-
Egen, J.G., Kuhns, M.S., and Allison, J.P. (2002). CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat Immunol 3, 611-618. (Pubitemid 34752469)
-
(2002)
Nature Immunology
, vol.3
, Issue.7
, pp. 611-618
-
-
Egen, J.G.1
Kuhns, M.S.2
Allison, J.P.3
-
6
-
-
33644765865
-
Cytotoxic T lymphocyte antigen-4 promoter variants in breast cancer
-
DOI 10.1016/j.cancergencyto.2005.07.020, PII S0165460805004231
-
Erfani, N., Razmkhah, M., Talei, A.R., Pezeshki, A.M., Doroudchi, M., Monabati, A., and Ghaderi, A. (2006). Cytotoxic T lymphocyte antigen-4 promoter variants in breast cancer. Cancer Genet Cytogenet 165, 114-120. (Pubitemid 43343504)
-
(2006)
Cancer Genetics and Cytogenetics
, vol.165
, Issue.2
, pp. 114-120
-
-
Erfani, N.1
Razmkhah, M.2
Talei, A.R.3
Pezeshki, A.M.4
Doroudchi, M.5
Monabati, A.6
Ghaderi, A.7
-
7
-
-
0030631546
-
Advances in the diagnosis and treatment of adenocarcinoma of the pancreas
-
Evans, D.B., Lee, J.E., Pisters, P.W., Charnsangavej, C., Ellis, L.M., Chiao, P.J., Lenzi, R., and Abbruzzese, J.L. (1997). Advances in the diagnosis and treatment of adenocarcinoma of the pancreas. Cancer Treat Res 90, 109-125.
-
(1997)
Cancer Treat Res
, vol.90
, pp. 109-125
-
-
Evans, D.B.1
Lee, J.E.2
Pisters, P.W.3
Charnsangavej, C.4
Ellis, L.M.5
Chiao, P.J.6
Lenzi, R.7
Abbruzzese, J.L.8
-
8
-
-
74749094000
-
E-cadherin-160 C/A promoter polymorphism and risk of pancreatic carcinoma in Chinese population
-
Fei, Y., Hu, J., Liu, S., Liu, X., Wang, F., and Gong, J. (2010).E-cadherin-160 C/A promoter polymorphism and risk of pancreatic carcinoma in Chinese population. Cancer Genet Cytogenet 197, 25-31.
-
(2010)
Cancer Genet Cytogenet
, vol.197
, pp. 25-31
-
-
Fei, Y.1
Hu, J.2
Liu, S.3
Liu, X.4
Wang, F.5
Gong, J.6
-
9
-
-
33746092947
-
Immune suppression in the tumor microenvironment
-
DOI 10.1097/01.cji.0000199193.29048.56, PII 0000237120060500000001
-
Gajewski, T.F., Meng, Y., and Harlin, H. (2006). Immune suppression in the tumor microenvironment. J Immunother 29, 233-240. (Pubitemid 44297291)
-
(2006)
Journal of Immunotherapy
, vol.29
, Issue.3
, pp. 233-240
-
-
Gajewski, T.F.1
Meng, Y.2
Harlin, H.3
-
10
-
-
0036180686
-
CTLA-4 regulates cell cycle progression during a primary immune response
-
DOI 10.1002/1521-4141(200202)32:2<366::AID-IMMU366>3.0.CO;2-5
-
Greenwald, R.J., Oosterwegel, M.A., van der Woude, D., Kubal, A., Mandelbrot, D.A., Boussiotis, V.A., and Sharpe, A.H. (2002). CTLA-4 regulates cell cycle progression during a primary immune response. Eur J Immunol 32, 366-373. (Pubitemid 34173328)
-
(2002)
European Journal of Immunology
, vol.32
, Issue.2
, pp. 366-373
-
-
Greenwald, R.J.1
Oosterwegel, M.A.2
Van Der Woude, D.3
Kubal, A.4
Mandelbrot, D.A.5
Boussiotis, V.A.6
Sharpe, A.H.7
-
11
-
-
36348998540
-
CTLA-4 gene promoter and exon 1 polymorphisms in Iranian patients with gastric and colorectal cancers
-
DOI 10.1111/j.1440-1746.2007.04862.x
-
Hadinia, A., Hossieni, S.V., Erfani, N., Saberi-Firozi, M., Fattahi, M.J., and Ghaderi, A. (2007). CTLA-4 gene promoter and exon 1 polymorphisms in Iranian patients with gastric and colorectal cancers. J Gastroenterol Hepatol 22, 2283-2287. (Pubitemid 350145629)
-
(2007)
Journal of Gastroenterology and Hepatology
, vol.22
, Issue.12
, pp. 2283-2287
-
-
Hadinia, A.1
Hossieni, S.V.2
Erfani, N.3
Saberi-Firozi, M.4
Fattahi, M.J.5
Ghaderi, A.6
-
12
-
-
33749317518
-
+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions
-
DOI 10.1158/1078-0432.CCR-06-0369
-
Hiraoka, N., Onozato, K., Kosuge, T., and Hirohashi, S. (2006).Prevalence of FOXP3 + regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions. Clin Cancer Res 12, 5423-5434. (Pubitemid 44497257)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.18
, pp. 5423-5434
-
-
Hiraoka, N.1
Onozato, K.2
Kosuge, T.3
Hirohashi, S.4
-
13
-
-
0344341626
-
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
-
DOI 10.1073/pnas.0830997100
-
Hodi, F.S., Mihm, M.C., Soiffer, R.J., Haluska, F.G., Butler, M., Seiden, M.V., Davis, T., Henry-Spires, R., MacRae, S., Willman, A., Padera, R., Jaklitsch, M.T., Shankar, S., Chen, T.C., Korman, A., Allison, J.P., and Dranoff, G. (2003). Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc Natl Acad Sci USA 100, 4712-4717. (Pubitemid 36457795)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.8
, pp. 4712-4717
-
-
Hodi, F.S.1
Mihm, M.C.2
Soiffer, R.J.3
Haluska, F.G.4
Butler, M.5
Seiden, M.V.6
Davis, T.7
Henry-Spires, R.8
MacRae, S.9
Willman, A.10
Padera, R.11
Jaklitsch, M.T.12
Shankar, S.13
Chen, T.C.14
Korman, A.15
Allison, J.P.16
Dranoff, G.17
-
14
-
-
33846457870
-
Cancer statistics, 2007
-
Jemal, A., Siegel, R., Ward, E., Murray, T., Xu, J., and Thun, M.J. (2007). Cancer statistics, 2007. CA Cancer J Clin 57, 43-66. (Pubitemid 46148091)
-
(2007)
Ca-A Cancer Journal for Clinicians
, vol.57
, Issue.1
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Thun, M.J.6
-
15
-
-
0029899783
-
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
-
DOI 10.1084/jem.183.6.2533
-
Krummel, M.F., and Allison, J.P. (1996). CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J Exp Med 183, 2533-2540. (Pubitemid 26192363)
-
(1996)
Journal of Experimental Medicine
, vol.183
, Issue.6
, pp. 2533-2540
-
-
Krummel, M.F.1
Allison, J.P.2
-
16
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach, D.R., Krummel, M.F., and Allison, J.P. (1996). Enhancement of antitumor immunity by CTLA-4 blockade. Science 271, 1734-1736. (Pubitemid 26102823)
-
(1996)
Science
, vol.271
, Issue.5256
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
17
-
-
0035346140
-
CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms
-
DOI 10.1038/sj.gene.6363752
-
Ligers, A., Teleshova, N., Masterman, T., Huang, W.X., and Hillert, J. (2001). CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms. Genes Immun 2, 145-152. (Pubitemid 33674879)
-
(2001)
Genes and Immunity
, vol.2
, Issue.3
, pp. 145-152
-
-
Ligers, A.1
Teleshova, N.2
Masterman, T.3
Huang, W.-X.4
Hillert, J.5
-
18
-
-
82955170680
-
Cytotoxic T-lymphocyte antigen-4 polymorphisms and susceptibility to osteosarcoma
-
[Epub ahead of print]; DOI:10.1089/dna.2011.1269
-
Liu, Y., He, Z., Feng, D., Shi, G., Gao, R., Wu, X., Song, W., and Yuan, W. (2011). Cytotoxic T-lymphocyte antigen-4 polymorphisms and susceptibility to osteosarcoma. DNA Cell Biol [Epub ahead of print]; DOI:10.1089/dna.2011.1269.
-
(2011)
DNA Cell Biol [Epub Ahead of
-
-
Liu, Y.1
He, Z.2
Feng, D.3
Shi, G.4
Gao, R.5
Wu, X.6
Song, W.7
Yuan, W.8
-
19
-
-
33747893112
-
reg) is induced by pancreas adenocarcinoma
-
DOI 10.1097/01.cji.0000205644.43735.4e, PII 0000237120060700000008
-
Liyanage, U.K., Goedegebuure, P.S., Moore, T.T., Viehl, C.T., Moo-Young, T.A., Larson, J.W., Frey, D.M., Ehlers, J.P., Eberlein, T.J., and Linehan, D.C. (2006). Increased prevalence of regulatory T cells (Treg) is induced by pancreas adenocarcinoma. J Immunother 29, 416-424. (Pubitemid 44288954)
-
(2006)
Journal of Immunotherapy
, vol.29
, Issue.4
, pp. 416-424
-
-
Liyanage, U.K.1
Goedegebuure, P.S.2
Moore, T.T.3
Viehl, C.T.4
Moo-Young, T.A.5
Larson, J.W.6
Frey, D.M.7
Ehlers, J.P.8
Eberlein, T.J.9
Linehan, D.C.10
-
20
-
-
48149092796
-
Clinical significance and regulation of the costimulatory molecule B7-H1 in pancreatic cancer
-
Loos, M., Giese, N.A., Kleeff, J., Giese, T., Gaida, M.M., Bergmann, F., Laschinger, M.W., Bü chler, M., and Friess, H. (2008).Clinical significance and regulation of the costimulatory molecule B7-H1 in pancreatic cancer. Cancer Lett 268, 98-109.
-
(2008)
Cancer Lett
, vol.268
, pp. 98-109
-
-
Loos, M.1
Giese, N.A.2
Kleeff, J.3
Giese, T.4
Gaida, M.M.5
Bergmann, F.6
Laschinger, M.W.7
Bü Chler, M.8
Friess, H.9
-
21
-
-
21544432144
-
+ regulatory T cells in wild-type hosts
-
DOI 10.1073/pnas.0503852102
-
Nishikawa, H., Kato, T., Tawara, I., Takemitsu, T., Saito, K., Wang, L., Ikarashi, Y., Wakasugi, H., Nakayama, T., Taniguchi, M., Kuribayashi, K., Old, L.J., and Shiku, H. (2005). Accelerated chemically induced tumor development mediated by CD4 + CD25 + regulatory T cells in wild-type hosts. Proc Natl Acad Sci USA 102, 9253-9257. (Pubitemid 40923550)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.26
, pp. 9253-9257
-
-
Nishikawa, H.1
Kato, T.2
Tawara, I.3
Takemitsu, T.4
Saito, K.5
Wang, L.6
Ikarashi, Y.7
Wakasugi, H.8
Nakayama, T.9
Taniguchi, M.10
Kuribayashi, K.11
Old, L.J.12
Shiku, H.13
-
22
-
-
0033019735
-
CTLA-4 and T cell activation
-
DOI 10.1016/S0952-7915(99)80047-8
-
Oosterwegel, M.A., Greenwald, R.J., Mandelbrot, D.A., Lorsbach, R.B., and Sharpe, A.H. (1999). CTLA-4 and T cell activation. Curr Opin Immunol 11, 294-300. (Pubitemid 29263957)
-
(1999)
Current Opinion in Immunology
, vol.11
, Issue.3
, pp. 294-300
-
-
Oosterwegel, M.A.1
-
23
-
-
77649188501
-
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1, 5p15.33
-
Petersen, G.M., Amundadottir, L., Fuchs, C.S., Kraft, P., Stolzenberg-Solomon, R.Z., Jacobs, K.B., et al. (2010). A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1, 5p15.33. Nat Genet 42, 224-228.
-
(2010)
Nat Genet
, vol.42
, pp. 224-228
-
-
Petersen, G.M.1
Amundadottir, L.2
Fuchs, C.S.3
Kraft, P.4
Stolzenberg-Solomon, R.Z.5
Jacobs, K.B.6
-
24
-
-
77958050577
-
Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma
-
Royal, R.E., Levy, C., Turner, K., Mathur, A., Hughes, M., Kammula, U.S., Sherry, R.M., Topalian, S.L., Yang, J.C., Lowy, I., and Rosenberg, S.A. (2010). Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma. J Immunother 33, 828-833.
-
(2010)
J Immunother
, vol.33
, pp. 828-833
-
-
Royal, R.E.1
Levy, C.2
Turner, K.3
Mathur, A.4
Hughes, M.5
Kammula, U.S.6
Sherry, R.M.7
Topalian, S.L.8
Yang, J.C.9
Lowy, I.10
Rosenberg, S.A.11
-
25
-
-
52049117144
-
Functional genetic variations in cytotoxic Tlymphocyte antigen 4 and susceptibility to multiple types of cancer
-
Sun, T., Zhou, Y., Yang, M., Hu, Z., Tan, W., Han, X., Shi, Y., Yao, J., Guo, Y., Yu, D., Tian, T., Zhou, X., Shen, H., and Lin, D. (2008). Functional genetic variations in cytotoxic Tlymphocyte antigen 4 and susceptibility to multiple types of cancer. Cancer Res 68, 7025-7034.
-
(2008)
Cancer Res
, vol.68
, pp. 7025-7034
-
-
Sun, T.1
Zhou, Y.2
Yang, M.3
Hu, Z.4
Tan, W.5
Han, X.6
Shi, Y.7
Yao, J.8
Guo, Y.9
Yu, D.10
Tian, T.11
Zhou, X.12
Shen, H.13
Lin, D.14
-
26
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol, E.A., Borriello, F., Schweitzer, A.N., Lynch, W.P., Bluestone, J.A., and Sharpe, A.H. (1995). Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3, 541-547.
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
27
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
DOI 10.1038/nature01621
-
Ueda, H., Howson, J.M., Esposito, L., Heward, J., Snook, H., Chamberlain, G., Rainbow, D.B., Hunter, K.M., Smith, A.N., Di Genova, G., Herr, M.H., Dahlman, I., Payne, F., Smyth, D., Lowe, C., Twells, R.C., Howlett, S., Healy, B., Nutland, S., Rance, H.E., Everett, V., Smink, L.J., Lam, A.C., Cordell, H.J., Walker, N.M., Bordin, C., Hulme, J., Motzo, C., Cucca, F., Hess, J.F., Metzker, M.L., Rogers, J., Gregory, S., Allahabadia, A., Nithiyananthan, R., Tuomilehto-Wolf, E., Tuomilehto, J., Bingley, P., Gillespie, K.M., Undlien, D.E., Rønningen, K.S., Guja, C., Ionescu-Tîrgovisxte, C., Savage, D.A., Maxwell, A.P., Carson, D.J., Patterson, C.C., Franklyn, J.A., Clayton, D.G., Peterson, L.B., Wicker, L.S., Todd, J.A., and Gough, S.C. (2003). Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423, 506-511. (Pubitemid 36648570)
-
(2003)
Nature
, vol.423
, Issue.6939
, pp. 506-511
-
-
Ueda, H.1
Howson, J.M.M.2
Esposito, L.3
Heward, J.4
Snook, H.5
Chamberlain, G.6
Rainbow, D.B.7
Hunter, K.M.D.8
Smith, A.N.9
Di Genova, G.10
Herr, M.H.11
Dahlman, I.12
Payne, F.13
Smyth, D.14
Lowe, C.15
Twells, R.C.J.16
Howlett, S.17
Healy, B.18
Nutland, S.19
Rance, H.E.20
Everett, V.21
Smink, L.J.22
Lam, A.C.23
Cordell, H.J.24
Walker, N.M.25
Bordin, C.26
Hulme, J.27
Motzo, C.28
Cucca, F.29
Hess, J.F.30
Metzker, M.L.31
Rogers, J.32
Gregory, S.33
Allahabadia, A.34
Nithiyananthan, R.35
Tuomilehto-Wolf, E.36
Tuomilehto, J.37
Bingley, P.38
Gillespie, K.M.39
Undlien, D.E.40
Ronningen, K.S.41
Guja, C.42
Ionescu-Tirgoviste, C.43
Savage, D.A.44
Maxwell, A.P.45
Carson, D.J.46
Patterson, C.C.47
Franklyn, J.A.48
Clayton, D.G.49
Peterson, L.B.50
Wicker, L.S.51
Todd, J.A.52
Gough, S.C.L.53
more..
|