Faecal calprotectin in HIV-infected, HAART-naïve ugandan children

Journal of Pediatric Gastroenterology and Nutrition

Volumn 54, Issue 6, 2012, Pages 785-790

  Hestvik, E ^a   Olafsdottir, E ^b   Tylleskar, T ^a   Aksnes, L ^a   Kaddu Mulindwa, D ^d   Ndeezi, G ^c   Tumwine, J K ^c   Grahnquist, L ^e  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^c Department of Paediatrics and Child Health ^*  (Uganda)

^d MAKERERE UNIVERSITY MEDICAL SCHOOL   (Uganda)

^e KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Children; Faecal calprotectin; HIV AIDS; Uganda Africa

Indexed keywords

CALGRANULIN; FECES CALPROTECTIN; UNCLASSIFIED DRUG;

ARTICLE; CD4 LYMPHOCYTE COUNT; CHILD; CONTROLLED STUDY; DIARRHEA; ENTERITIS; FECES ANALYSIS; FECES LEVEL; FEMALE; HEALTH SURVEY; HIV INFECTED HIGHLY ACTIVE ANTIRETROVIRAL THERAPY NAIVE PATIENT; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; REFERENCE VALUE; SCHOOL CHILD; UGANDA;

AGE FACTORS; ANTI-HIV AGENTS; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; CHILD; CHILD, PRESCHOOL; DIARRHEA; DISEASE PROGRESSION; FECES; FEMALE; GASTROENTERITIS; HIV INFECTIONS; HUMANS; INFANT; INTERVIEWS AS TOPIC; LEUKOCYTE L1 ANTIGEN COMPLEX; MALE; REFERENCE VALUES; RISK FACTORS; UGANDA;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84861336554     PISSN: 02772116     EISSN: 15364801     Source Type: Journal    
DOI: 10.1097/MPG.0b013e318241a683     Document Type: Article

References (40)

1. Uganda AIDS Commission UNGASS country progress report, Uganda, January 2008-December 2009. http://www.aidsuganda.org. Published 2010. Accessed April 11, 2012.
2. World Health Organization. UNAIDS 2008 Report on Global AIDS Epidemic. Geneva: WHO; 2008.
3. Sharpstone D, Gazzard B. Gastrointestinal manifestations of HIV infection. Lancet 1996;348:379-83. (Pubitemid 26261514)
4. Wallace MR, Brann OS. Gastrointestinal manifestations of HIV infection. Curr Gastroenterol Rep 2000;2:283-93.
5. Kearney DJ, Steuerwald M, Koch J, et al. A prospective study of endoscopy in HIV-associated diarrhea. Am J Gastroenterol 1999;94: 596-602. (Pubitemid 29124852)
6. Knox TA, Spiegelman D, Skinner SC, et al. Diarrhea and abnormalities of gastrointestinal function in a cohort of men and women with HIV infection. Am J Gastroenterol 2000;95:3482-9.
7. Battan R, Raviglione MC, Palagiano A, et al. Helicobacter pylori infection in patients with acquired immune deficiency syndrome. Am J Gastroenterol 1990;85:1576-9.
8. Narwal S, Galeano NF, Pottenger E, et al. Idiopathic esophageal ulcers in a child with AIDS. J Pediatr Gastroenterol Nutr 1997;24:211-4. (Pubitemid 27172129)
9. Senya C, Mehta A, Harwell JI, et al. Spectrum of opportunistic infections in hospitalized HIV-infected patients in Phnom Penh, Cambodia. Int J STD AIDS 2003;14:411-6. (Pubitemid 36791763)
10. Cello JP, Day LW. Idiopathic AIDS enteropathy and treatment of gastrointestinal opportunistic pathogens. Gastroenterology 2009;136: 1952-65.
11. Tumwine JK, Kekitiinwa A, Bakeera-Kitaka S, et al. Cryptosporidiosis and microsporidiosis in Ugandan children with persistent diarrhea with and without concurrent infection with the human immunodeficiency virus. Am J Trop Med Hyg 2005;73:921-5. (Pubitemid 41688469)
12. Spira R, Lepage P, Msellati P, et al. Natural history of human immunodeficiency virus type 1 infection in children: a five-year prospective study in Rwanda. Mother-to-Child HIV-1 Transmission Study Group. Pediatrics 1999;104:e56.
13. Brenchley JM, Douek DC. The mucosal barrier and immune activation in HIV pathogenesis. Curr Opin HIV AIDS 2008;3:356-61. (Pubitemid 351521021)
14. Brenchley JM, Price DA, Schacker TW, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006;12:1365-71. (Pubitemid 44924494)
15. Gisbert JP, McNicholl AG. Questions and answers on the role of faecal calprotectin as a biological marker in inflammatory bowel disease. Dig Liver Dis 2009;41:56-66.
16. Roseth AG, Fagerhol MK, Aadland E, et al. Assessment of the neutrophil dominating protein calprotectin in feces. A methodologic study. Scand J Gastroenterol 1992;27:793-8.
17. Ton H, Brandsnes, Dale S, et al. Improved assay for fecal calprotectin. Clin Chim Acta 2000;292:41-54. (Pubitemid 30109253)
18. Fagerberg UL, Loof L, Merzoug RD, et al. Fecal calprotectin levels in healthy children studied with an improved assay. J Pediatr Gastroenterol Nutr 2003;37:468-72. (Pubitemid 39274493)
19. Hestvik E, Tumwine JK, Tylleskar T, et al. Faecal calprotectin concentrations in apparently healthy children aged 0-12 years in urban Kampala, Uganda: a community-based survey. BMC Pediatr 2011;11:9.
20. Roseth AG, Aadland E, Jahnsen J, et al. Assessment of disease activity in ulcerative colitis by faecal calprotectin, a novel granulocyte marker protein. Digestion 1997;58:176-80. (Pubitemid 27163169)
21. Bunn SK, Bisset WM, Main MJ, et al. Fecal calprotectin as a measure of disease activity in childhood inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2001;32:171-7. (Pubitemid 32280632)
22. Olafsdottir E, Aksnes L, Fluge G, et al. Faecal calprotectin levels in infants with infantile colic, healthy infants, children with inflammatory bowel disease, children with recurrent abdominal pain and healthy children. Acta Paediatr 2002;91:45-50. (Pubitemid 34151218)
23. Hanevik K, Hausken T, Morken MH, et al. Persisting symptoms and duodenal inflammation related to Giardia duodenalis infection. J Infect 2007;55:524-30. (Pubitemid 350082473)
24. Berni Canani R, Rapacciuolo L, Romano MT, et al. Diagnostic value of faecal calprotectin in paediatric gastroenterology clinical practice. Dig Liver Dis 2004;36:467-70. (Pubitemid 41115450)
25. Gori A, Tincati C, Rizzardini G, et al. Early impairment of gut function and gut flora supporting a role for alteration of gastrointestinal mucosa in human immunodeficiency virus pathogenesis. J Clin Microbiol 2008; 46:757-8. (Pubitemid 351231331)
26. Schwartz R, Lu Y, Villines D, et al. Effect of human immunodeficiency virus infection on S100A8/A9 inhibition of peripheral neutrophils oxidative metabolism. Biomed Pharmacother 2010;64:572-5.
27. Roseth AG, Kristinsson J, Fagerhol MK, et al. Faecal calprotectin: anovel test for the diagnosis of colorectal cancer? Scand J Gastroenterol 1993;28:1073-6. (Pubitemid 23350726)
28. Savino F, Castagno E, Calabrese R, et al. High faecal calprotectin levels in healthy, exclusively breast-fed infants. Neonatology 2009;97:299-304.
29. Hestvik E, Tylleskar T, Ndeezi G, et al. Prevalence of Helicobacter pylori in HIV-infected, HAART-naive Ugandan children: a hospitalbased survey. J Int AIDS Soc 2011;14:34.
30. World Health Organization. Antiretroviral Therapy of HIV Infection in Infants and Children; Recommendations for a Public Health Approach. Geneva: WHO; 2006.
31. World Health Organization. InterimWHOClinical Staging of HIV/AIDS and HIV/AIDS Case Definitions for Surveillance. Geneva: WHO; 2005.
32. World Health Organization. Physical Status: The Use and Interpretation of Anthropometry. Geneva: WHO; 1995.
33. World Health Organization. WHO Anthro for personal computers, version 3.2.2, 2011: software for assessing growth and development of the world's children. http://www.who.int/childgrowth/software/en.Published 2010. Accessed April 11, 2012.
34. World Health Organization. WHO AnthroPlus for personal computers manual: software for assessing growth of the world's children and adolescents. http://www.who.int/growthref/tools/en. Published 2009.Accessed April 11, 2012.
35. World Health Organization. Towards Universal Access: Scaling Up Priority HIV/AIDS Interventions in the Health Sector. Progress Report 2010. Geneva: WHO; 2010.
36. Bjarnason I, Sharpstone DR, Francis N, et al. Intestinal inflammation, ileal structure and function in HIV. AIDS 1996;10:1385-91. (Pubitemid 26333937)
37. Keating J, Bjarnason I, Somasundaram S, et al. Intestinal absorptive capacity, intestinal permeability and jejunal histology in HIV and their relation to diarrhoea. Gut 1995;37:623-9.
38. Sharpstone D, Neild P, Crane R, et al. Small intestinal transit, absorption, and permeability in patients with AIDS with and without diarrhoea. Gut 1999;45:70-6. (Pubitemid 29301848)
39. Greenson JK, Belitsos PC, Yardley JH, et al. AIDS enteropathy: occult enteric infections and duodenal mucosal alterations in chronic diarrhea. Ann Intern Med 1991;114:366-72.
40. Casellas F, Borruel N, Antolin M, et al. Fecal excretion of deoxyribonucleic acid in long-term follow-up of patients with inactive ulcerative colitis. Inflamm Bowel Dis 2007;13:386-90. (Pubitemid 46668242)