-
1
-
-
69949107080
-
Clinical review: Intensive insulin therapy in critically ill patients: NICE-SUGAR or Leuven blood glucose target?
-
Van den Berghe, G. et al. Clinical review: Intensive insulin therapy in critically ill patients: NICE-SUGAR or Leuven blood glucose target? J. Clin. Endocrinol. Metab. 94, 3163-3170 (2009).
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 3163-3170
-
-
Van Den Berghe, G.1
-
2
-
-
62449193994
-
Glucose normalization and outcomes in patients with acute myocardial infarction
-
Kosiborod, M. et al. Glucose normalization and outcomes in patients with acute myocardial infarction. Arch. Intern. Med. 169, 438-446 (2009).
-
(2009)
Arch. Intern. Med.
, vol.169
, pp. 438-446
-
-
Kosiborod, M.1
-
4
-
-
78651315324
-
Executive summary: Standards of medical care in diabetes-2011
-
American Diabetes Association.
-
American Diabetes Association. Executive summary: standards of medical care in diabetes-2011. Diabetes Care 34 (Suppl 1.), S4-S10 (2011).
-
(2011)
Diabetes Care
, vol.34
, Issue.SUPPL. 1
-
-
-
5
-
-
79951601800
-
Use of intensive insulin therapy for the management of glycemic control in hospitalized patients: A clinical practice guideline from the American College of Physicians
-
Clinical Guidelines Committee of the American College of Physicians.
-
Qaseem, A., Humphrey, L. L., Chou, R., Snow, V. & Shekelle, P. Clinical Guidelines Committee of the American College of Physicians. Use of intensive insulin therapy for the management of glycemic control in hospitalized patients: a clinical practice guideline from the American College of Physicians. Ann. Intern. Med. 154, 260-267 (2011).
-
(2011)
Ann. Intern. Med.
, vol.154
, pp. 260-267
-
-
Qaseem, A.1
Humphrey, L.L.2
Chou, R.3
Snow, V.4
Shekelle, P.5
-
6
-
-
37549020378
-
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock 2008
-
Dellinger, R. P. et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit. Care Med. 36, 296-327 (2008).
-
(2008)
Crit. Care Med.
, vol.36
, pp. 296-327
-
-
Dellinger, R.P.1
-
7
-
-
41649088783
-
-
Erratum
-
Erratum in: Crit. Care Med. 36, 1394-1396 (2008).
-
(2008)
Crit. Care Med.
, vol.36
, pp. 1394-1396
-
-
-
8
-
-
58149301489
-
Intensive glycemic control and the prevention of cardiovascular events: Implications of the ACCORD
-
ADVANCE, and VA Diabetes Trials: a position statement of the American Diabetes Association and a Scientific Statement of the American College of Cardiology Foundation and the American Heart Association
-
Skyler, J. S. et al. Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA Diabetes Trials: a position statement of the American Diabetes Association and a Scientific Statement of the American College of Cardiology Foundation and the American Heart Association. J. Am. Coll. Cardiol. 53, 298-304 (2009).
-
(2009)
J. Am. Coll. Cardiol.
, vol.53
, pp. 298-304
-
-
Skyler, J.S.1
-
9
-
-
0035829852
-
Intensive insulin therapy in the critically ill patients
-
Van den Berghe, G. et al. Intensive insulin therapy in the critically ill patients. N. Engl. J. Med. 345, 1359-1367 (2001).
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 1359-1367
-
-
Van Den Berghe, G.1
-
10
-
-
33645819422
-
ESPEN Guidelines on Enteral Nutrition: Intensive care
-
DOI 10.1016/j.clnu.2006.01.021, PII S0261561406000410
-
Kreymann, K. G. et al. ESPEN guidelines on enteral nutrition: intensive care. Clin. Nutr. 25, 210-223 (2006). (Pubitemid 43811686)
-
(2006)
Clinical Nutrition
, vol.25
, Issue.2
, pp. 210-223
-
-
Kreymann, K.G.1
Berger, M.M.2
Deutz, N.E.P.3
Hiesmayr, M.4
Jolliet, P.5
Kazandjiev, G.6
Nitenberg, G.7
Van Den Berghe, G.8
Wernerman, J.9
Ebner, C.10
Hartl, W.11
Heymann, C.12
Spies, C.13
-
11
-
-
67949124622
-
ESPEN guidelines on parenteral nutrition: Intensive care
-
Singer, P. et al. ESPEN guidelines on parenteral nutrition: intensive care. Clin. Nutr. 28, 387-400 (2009).
-
(2009)
Clin. Nutr.
, vol.28
, pp. 387-400
-
-
Singer, P.1
-
12
-
-
0037326620
-
Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control
-
DOI 10.1097/01.CCM.0000045568.12881.10
-
Van den Berghe, G. et al. Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control. Crit. Care Med. 31, 359-366 (2003). (Pubitemid 36232926)
-
(2003)
Critical Care Medicine
, vol.31
, Issue.2
, pp. 359-366
-
-
Van Den Berghe, G.1
Wouters, P.J.2
Bouillon, R.3
Weekers, F.4
Verwaest, C.5
Schetz, M.6
Vlasselaers, D.7
Ferdinande, P.8
Lauwers, P.9
-
13
-
-
33845539898
-
Intensive insulin therapy in mixed medical/surgical intensive care units: Benefit versus harm
-
DOI 10.2337/db06-0855
-
Van den Berghe, G. et al. Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm. Diabetes 55, 3151-3159 (2006). (Pubitemid 44923655)
-
(2006)
Diabetes
, vol.55
, Issue.11
, pp. 3151-3159
-
-
Van Den Berghe, G.1
Wilmer, A.2
Milants, I.3
Wouters, P.J.4
Bouckaert, B.5
Bruyninckx, F.6
Bouillon, R.7
Schetz, M.8
-
14
-
-
33745320589
-
Survival benefits of intensive insulin therapy in critical illness: Impact of maintaining normoglycemia versus glycemia-independent actions of insulin
-
DOI 10.2337/diabetes.55.04.06.db05-1434
-
Ellger, B. et al. Survival benefits of intensive insulin therapy in critical illness: impact of maintaining normoglycaemia versus glycemia-independent actions of insulin. Diabetes 55, 1096-1105 (2006). (Pubitemid 44100187)
-
(2006)
Diabetes
, vol.55
, Issue.4
, pp. 1096-1105
-
-
Ellger, B.1
Debaveye, Y.2
Vanhorebeek, I.3
Langouche, L.4
Giulietti, A.5
Van Etten, E.6
Herijgers, P.7
Mathieu, C.8
Van Den Berghe, G.9
-
15
-
-
32044465949
-
Intensive insulin therapy in the medical ICU
-
DOI 10.1056/NEJMoa052521
-
Van den Berghe, G. et al. Intensive insulin therapy in the medical ICU. N. Engl. J. Med. 354, 449-461 (2006). (Pubitemid 43200296)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.5
, pp. 449-461
-
-
Van Den Berghe, G.1
Wilmer, A.2
Hermans, G.3
Meersseman, W.4
Wouters, P.J.5
Milants, I.6
Van Wijngaerden, E.7
Bobbaers, H.8
Bouillon, R.9
-
16
-
-
40449115119
-
Tight blood glucose control is renoprotective in critically ill patients
-
DOI 10.1681/ASN.2006101091
-
Schetz, M., Vanhorebeek, I., Wouters, P. J., Wilmer, A. & Van den Berghe, G. Tight blood glucose control is renoprotective in critically ill patients. J. Am. Soc. Nephrol. 19, 571-578 (2008). (Pubitemid 351355400)
-
(2008)
Journal of the American Society of Nephrology
, vol.19
, Issue.3
, pp. 571-578
-
-
Schetz, M.1
Vanhorebeek, I.2
Wouters, P.J.3
Wilmer, A.4
Van Den Berghe, G.5
-
17
-
-
59749098319
-
Intensive insulin therapy for patients in paediatric intensive care: A prospective, randomized controlled study
-
Vlasselaers, D. et al. Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomized controlled study. Lancet 373, 547-556 (2009).
-
(2009)
Lancet
, vol.373
, pp. 547-556
-
-
Vlasselaers, D.1
-
18
-
-
33947546779
-
Achieving Tight Glycemic Control in the Operating Room: Lessons Learned from 12 Years in the Trenches of a Paradigm Shift in Anesthetic Care
-
DOI 10.1053/j.semtcvs.2007.01.004, PII S1043067907000093, Diabetes, Hyperglycemia, and Cardiac Surgery Patient
-
Furnary, A. P., Cheek, D. B., Holmes, S. C., Howell, W. L. & Kelly, S. P. Achieving tight glycemic control in the operating room: lessons learned from 12 years in the trenches of a paradigm shift in anesthetic care. Semin. Thorac. Cardiovasc. Surg. 18, 339-345 (2006). (Pubitemid 46464519)
-
(2006)
Seminars in Thoracic and Cardiovascular Surgery
, vol.18
, Issue.4
, pp. 339-345
-
-
Furnary, A.P.1
Cheek, D.B.2
Holmes, S.C.3
Howell, W.L.4
Kelly, S.P.5
-
19
-
-
3442899889
-
Effect of an intensive glucose management protocol on the mortality of critically Ill adult patients
-
Krinsley, J. S. Effect of an intensive glucose management protocol on the mortality of critically ill adult patients. Mayo Clin. Proc. 79, 992-1000 (2004). (Pubitemid 39007018)
-
(2004)
Mayo Clinic Proceedings
, vol.79
, Issue.8
, pp. 992-1000
-
-
Krinsley, J.S.1
-
20
-
-
23244441052
-
-
Erratum
-
Erratum in: Mayo Clin. Proc. 80, 1101 (2005).
-
(2005)
Mayo Clin. Proc.
, vol.80
, pp. 1101
-
-
-
21
-
-
34247546032
-
Intensive Insulin Protocol Improves Glucose Control and Is Associated with a Reduction in Intensive Care Unit Mortality
-
DOI 10.1016/j.jamcollsurg.2006.12.047, PII S1072751507002207
-
Reed, C. C. et al. Intensive insulin protocol improves glucose control and is associated with a reduction in intensive care unit mortality. J. Am. Coll. Surg. 204, 1048-1054; discussion 1054-1055 (2007). (Pubitemid 46661216)
-
(2007)
Journal of the American College of Surgeons
, vol.204
, Issue.5
, pp. 1048-1054
-
-
Reed, C.C.1
Stewart, R.M.2
Sherman, M.3
Myers, J.G.4
Corneille, M.G.5
Larson, N.6
Gerhardt, S.7
Beadle, R.8
Gamboa, C.9
Dent, D.10
Cohn, S.M.11
Pruitt Jr., B.A.12
-
22
-
-
58149339793
-
Tight perioperative glucose control is associated with a reduction in renal impairment and renal failure in non-diabetic cardiac surgical patients
-
Lecomte, P. et al. Tight perioperative glucose control is associated with a reduction in renal impairment and renal failure in non-diabetic cardiac surgical patients. Crit. Care 12, R154 (2008).
-
(2008)
Crit. Care
, vol.12
-
-
Lecomte, P.1
-
23
-
-
63249128249
-
Intensive versus conventional glucose control in critically ill patients
-
Finfer, S. et al. Intensive versus conventional glucose control in critically ill patients. N. Engl. J. Med. 360, 1283-1297 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1283-1297
-
-
Finfer, S.1
-
24
-
-
58149231157
-
Tight glucose control in the intensive care unit: Are glucose meters up to the task?
-
Scott, M. G., Bruns, D. E., Boyd, J. C. & Sacks, D. B. Tight glucose control in the intensive care unit: are glucose meters up to the task? Clin. Chem. 55, 18-20 (2009).
-
(2009)
Clin Chem.
, vol.55
, pp. 18-20
-
-
Scott, M.G.1
Bruns, D.E.2
Boyd, J.C.3
Sacks, D.B.4
-
25
-
-
84887279193
-
Blood glucose measurements in arterial blood of intensive care unit patients submitted to tight glycemic control: Agreement between bedside tests
-
Vlasselaers, D. et al. Blood glucose measurements in arterial blood of intensive care unit patients submitted to tight glycemic control: agreement between bedside tests. J. Diabetes Sci. Technol. 2, 932-938 (2008).
-
(2008)
J. Diabetes Sci. Technol.
, vol.2
, pp. 932-938
-
-
Vlasselaers, D.1
-
26
-
-
79960435703
-
Glycemic control in the ICU
-
Egi, M., Finfer, S. & Bellomo, R. Glycemic control in the ICU. Chest 140, 212-220 (2011).
-
(2011)
Chest
, vol.140
, pp. 212-220
-
-
Egi, M.1
Finfer, S.2
Bellomo, R.3
-
27
-
-
77954354586
-
Could susceptibility to low hematocrit interference have compromised the results of the NICE-SUGAR trial?
-
Cembrowski, G. S. et al. Could susceptibility to low hematocrit interference have compromised the results of the NICE-SUGAR trial? Clin. Chem. 56, 1193-1195 (2010).
-
(2010)
Clin Chem.
, vol.56
, pp. 1193-1195
-
-
Cembrowski, G.S.1
-
28
-
-
71549156881
-
Monte Carlo simulation in establishing analytical requirements for clinical laboratory tests: Meeting the clinical needs
-
Boyd, J. C. & Bruns, D. E. Monte Carlo simulation in establishing analytical requirements for clinical laboratory tests: meeting the clinical needs. Methods Enzymol. 467, 411-433 (2009).
-
(2009)
Methods Enzymol.
, vol.467
, pp. 411-433
-
-
Boyd, J.C.1
Bruns, D.E.2
-
29
-
-
77953148918
-
Glucose meter performance criteria for tight glycemic control estimated by simulation modeling
-
Karon, B. S., Boyd, J. C. & Klee, G. G. Glucose meter performance criteria for tight glycemic control estimated by simulation modeling. Clin. Chem. 56, 1091-1097 (2010).
-
(2010)
Clin. Chem.
, vol.56
, pp. 1091-1097
-
-
Karon, B.S.1
Boyd, J.C.2
Klee, G.G.3
-
30
-
-
29144475766
-
Reliability of point-of-care testing for glucose measurement in critically ill adults
-
DOI 10.1097/01.CCM.0000189939.10881.60
-
Kanji, S. et al. Reliability of point-of-care testing for glucose measurement in critically ill adults. Crit. Care Med. 33, 2778-2785 (2005). (Pubitemid 41816412)
-
(2005)
Critical Care Medicine
, vol.33
, Issue.12
, pp. 2778-2785
-
-
Kanji, S.1
Buffie, J.2
Hutton, B.3
Bunting, P.S.4
Singh, A.5
McDonald, K.6
Fergusson, D.7
McIntyre, L.A.8
Hebert, P.C.9
-
31
-
-
22944476109
-
Negative impact of hypocaloric feeding and energy balance on clinical outcome in ICU patients
-
DOI 10.1016/j.clnu.2005.03.006, PII S0261561405000543
-
Villet, S. et al. Negative impact of hypocaloric feeding and energy balance on clinical outcome in ICU patients. Clin. Nutr. 24, 502-509 (2005). (Pubitemid 41051903)
-
(2005)
Clinical Nutrition
, vol.24
, Issue.4
, pp. 502-509
-
-
Villet, S.1
-
32
-
-
67650470214
-
Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Medicine and American Society for Parenteral and Enteral Nutrition: Executive Summary
-
Martindale, R. G. et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Medicine and American Society for Parenteral and Enteral Nutrition: Executive Summary. Crit. Care Med. 37, 1757-1761 (2009).
-
(2009)
Crit. Care Med.
, vol.37
, pp. 1757-1761
-
-
Martindale, R.G.1
-
33
-
-
0042279261
-
Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients
-
Heyland, D. K., Dhaliwal, R., Drover, J. W., Gramlich, L. & Dodek, P. Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. J. Parenter. Enteral. Nutr. 27, 355-373 (2003). (Pubitemid 37022781)
-
(2003)
Journal of Parenteral and Enteral Nutrition
, vol.27
, Issue.5
, pp. 355-373
-
-
Heyland, D.K.1
Dhaliwal, R.2
Drover, J.W.3
Gramlich, L.4
Dodek, P.5
-
34
-
-
33645960420
-
Frequency of under-and overfeeding in mechanically ventilated ICU patients: Causes and possible consequences
-
Reid, C. Frequency of under-and overfeeding in mechanically ventilated ICU patients: causes and possible consequences. J. Hum. Nutr. Diet. 19, 13-22 (2006).
-
(2006)
J. Hum. Nutr. Diet.
, vol.19
, pp. 13-22
-
-
Reid, C.1
-
35
-
-
4143124337
-
Combination enteral and parenteral nutrition in critically ill patients: Harmful or beneficial? A systematic review of the evidence
-
Dhaliwal, R., Jurewitsch, B., Harrietha, D. & Heyland, D. K. Combination enteral and parenteral nutrition in critically ill patients: harmful or beneficial? A systematic review of the evidence. Intensive Care Med. 30, 1666-1671 (2004). (Pubitemid 39094972)
-
(2004)
Intensive Care Medicine
, vol.30
, Issue.8
, pp. 1666-1671
-
-
Dhaliwal, R.1
Jurewitsch, B.2
Harrietha, D.3
Heyland, D.K.4
-
36
-
-
80051648934
-
Early versus late parenteral nutrition in critically ill adults
-
Casaer, M. P. et al. Early versus late parenteral nutrition in critically ill adults. N. Engl. J. Med. 365, 506-517 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 506-517
-
-
Casaer, M.P.1
-
37
-
-
11444259403
-
Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients
-
DOI 10.1016/S0140-6736(04)17665-4, PII S0140673604176654
-
Vanhorebeek, I. et al. Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients. Lancet 365, 53-59 (2005). (Pubitemid 40082146)
-
(2005)
Lancet
, vol.365
, Issue.9453
, pp. 53-59
-
-
Vanhorebeek, I.1
Vos, R.D.2
Mesotten, D.3
Wouters, P.J.4
Wolf-Peeters, C.D.5
Van Den Berghe, G.6
-
38
-
-
23644461209
-
Intensive insulin therapy protects the endothelium of critically ill patients
-
DOI 10.1172/JCI25385
-
Langouche, L. et al. Intensive insulin therapy protects the endothelium of critically ill patients. J. Clin. Invest. 115, 2277-2286 (2005). (Pubitemid 41134169)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.8
, pp. 2277-2286
-
-
Langouche, L.1
Vanhorebeek, I.2
Vlasselaers, D.3
Vander Perre, S.4
Wouters, P.J.5
Skogstrand, K.6
Hansen, T.K.7
Van Den Berghe, G.8
-
39
-
-
17644386216
-
Insulin therapy protects the central and peripheral nervous system of intensive care patients
-
Van den Berghe, G., Schoonheydt, K., Becx, P., Bruyninckx, F. & Wouters, P. J. Insulin therapy protects the central and peripheral nervous system of intensive care patients. Neurology 64, 1348-1353 (2005). (Pubitemid 40570499)
-
(2005)
Neurology
, vol.64
, Issue.8
, pp. 1348-1353
-
-
Van Den Berghe, G.1
Schoonheydt, K.2
Becx, P.3
Bruyninckx, F.4
Wouters, P.J.5
-
40
-
-
67650472358
-
Tissue-specific glucose toxicity induces mitochondrial damage in a burn injury model of critical illness
-
Vanhorebeek, I. et al. Tissue-specific glucose toxicity induces mitochondrial damage in a burn injury model of critical illness. Crit. Care Med. 37, 1355-1364 (2009).
-
(2009)
Crit. Care Med.
, vol.37
, pp. 1355-1364
-
-
Vanhorebeek, I.1
-
41
-
-
68949206301
-
Hyperglycemic kidney damage in an animal model of prolonged critical illness
-
Vanhorebeek, I. et al. Hyperglycemic kidney damage in an animal model of prolonged critical illness. Kidney Int. 76, 512-520 (2009).
-
(2009)
Kidney Int.
, vol.76
, pp. 512-520
-
-
Vanhorebeek, I.1
-
42
-
-
85047691476
-
How does blood glucose control with insulin save lives in intensive care?
-
DOI 10.1172/JCI200423506
-
Van den Berghe, G. How does blood glucose control with insulin save lives in intensive care? J. Clin. Invest. 114, 1187-1195 (2004). (Pubitemid 40385286)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.9
, pp. 1187-1195
-
-
Van Den Berghe, G.1
-
43
-
-
35349016848
-
Effect of intensive insulin therapy on insulin sensitivity in the critically ill
-
DOI 10.1210/jc.2007-0813
-
Langouche, L. et al. Effect of intensive insulin therapy on insulin sensitivity in the critically ill. J. Clin. Endocrinol. Metab. 92, 3890-3897 (2007). (Pubitemid 47607638)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.10
, pp. 3890-3897
-
-
Langouche, L.1
Vander Perre, S.2
Wouters, P.J.3
D'Hoore, A.4
Hansen, T.K.5
Van Den Berghe, G.6
-
44
-
-
79953875974
-
Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients
-
Vanhorebeek, I. et al. Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients. J. Clin. Endocrinol. Metab. 96, E633-E645 (2011).
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
-
-
Vanhorebeek, I.1
-
45
-
-
78649704325
-
Autophagy and metabolism
-
Rabinowitz, J. D. & White, E. Autophagy and metabolism. Science 330, 1344-1348 (2010).
-
(2010)
Science
, vol.330
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
46
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine, B. & Kroemer, G. Autophagy in the pathogenesis of disease. Cell 132, 27-42 (2008).
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
|