Surgical site infections following colorectal cancer surgery: A randomized prospective trial comparing common and advanced antimicrobial dressing containing ionic silver

World Journal of Surgical Oncology

Volumn 10, Issue , 2012, Pages

  Biffi, Roberto ^a   Fattori, Luca ^b   Bertani, Emilio ^a   Radice, Davide ^a   Rotmensz, Nicole ^a   Misitano, Pasquale ^a   Cenciarelli, Sabine ^a   Chiappa, Antonio ^a   Tadini, Liliana ^a   Mancini, Marina ^a   Pesenti, Giovanni ^b   Andreoni, Bruno ^a   Nespoli, Angelo ^b  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b SAN GERARDO HOSPITAL   (Italy)

Author keywords

Colorectal cancer; Elective surgery; Hydrofiber dressing; Ionic silver; Surgical site infection

Indexed keywords

ANTIBIOTIC AGENT; AQUACEL; IONIC SILVER; SILVER; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BACTERIUM CULTURE; BODY MASS; CANCER SURGERY; CLINICAL ASSESSMENT; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; EDEMA; ELECTIVE SURGERY; ERYTHEMA; FEMALE; FEVER; HEMATOMA; HUMAN; INFECTION RATE; INFECTION RISK; LEUKOCYTOSIS; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NECROSIS; OUTCOME ASSESSMENT; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SHIVERING; SURGICAL INFECTION; SURGICAL WOUND; WOUND DRESSING;

ADOLESCENT; ADULT; AGED; ANTI-INFECTIVE AGENTS; BANDAGES; CARBOXYMETHYLCELLULOSE SODIUM; COLORECTAL NEOPLASMS; DOUBLE-BLIND METHOD; DRUG CARRIERS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NEOPLASM GRADING; PROGNOSIS; PROSPECTIVE STUDIES; SILVER; SURGICAL WOUND INFECTION; WOUND HEALING; YOUNG ADULT;

EID: 84861329391     PISSN: None     EISSN: 14777819     Source Type: Journal    
DOI: 10.1186/1477-7819-10-94     Document Type: Article

References (32)

1. Tang R, Chen HH, Wang YL, Changchien CR, Chen JS, Hsu KC, Chiang JM, Wang JY. Risk factors for surgical site infection after elective resection of the colon and rectum: a single-center prospective study of 2,809 consecutive patients. Ann Surg 2001, 234:181-189. 10.1097/00000658-200108000-00007, 1422004, 11505063.
2. Smith RL, Bohl JK, McElearney ST, Friel CM, Barclay MM, Sawyer RG, Foley EF. Wound infection after elective colorectal resection. Ann Surg 2004, 239:599-605. 10.1097/01.sla.0000124292.21605.99, 1356267, 15082963.
3. National Audit Office The Management and Control of Hospital-Acquired Infection in Acute NHS Trusts in England 2007, Her Majesty's Stationery Office, London, National Audit Office.
4. Bratzler DW, Houck PM, Richards C, Steele L, Dellinger EP, Fry DE, Wright C, Ma A, Carr K, Red L. Use of antimicrobial prophylaxis for major surgery: baseline results from the National Surgical Infection Prevention Project. Arch Surg 2005, 140:174-182. 10.1001/archsurg.140.2.174, 15724000.
5. Darouiche RO, Wall MJ, Itani KM, Otterson MF, Webb AL, Carrick MM, Miller HJ, Awad SS, Crosby CT, Mosier MC, Alsharif A, Berger DH. Chlorhexidine-alcohol versus povidone-iodine for surgical-site antisepsis. N Engl J Med 2010, 362:18-26. 10.1056/NEJMoa0810988, 20054046.
6. Percival SL, Slone W, Linton S, Okel T, Corum L, Thomas JG. The antimicrobial efficacy of a silver alginate dressing against a broad spectrum of clinically relevant wound isolates. Int Wound J 2011, 8:237-243. 10.1111/j.1742-481X.2011.00774.x, 21470369.
7. Lansdown AB. Silver. I: Its antibacterial properties and mechanism of action. J Wound Care 2002, 11(4):125-130.
8. Bowler PG, Jones SA, Walker M, Parsons D. Microbicidal properties of a silver-containing hydrofiber dressing against a variety of burn wound pathogens. J Burn Care Rehabil 2004, 25(2):192-196. 10.1097/01.BCR.0000112331.72232.1B, 15091147.
9. Storm-Versloot MN, Vos CG, Ubbink DT, Vermeulen H. Topical silver for preventing wound infection. Cochrane Database Syst Rev 2010, 3:CD006478.
10. Biffi R, Misitano P, Tadini L, Mancini M, Pace U, Andreoni B. Abdominal surgical site infection and advanced antimicrobial dressings. European Wound Management Association 2007 in Glasgow, Abstracts' book 2007, no. 29.
11. Ishizaka K, Kobayashi S, Machida T, Yoshida K. Randomized prospective comparison of fosfomycin and cefotiam for prevention of postoperative infection following urological surgery. J Infect Chemother 2007, 13:324-331. 10.1007/s10156-007-0544-5, 17982722.
12. Itani KMF, Wilson SE, Awad SS, Jensen EH, Finn TS, Abramson MA. Ertapenem versus cefotetan prophylaxis in elective colorectal surgery. N Engl J Med 2006, 355:2640-2651. 10.1056/NEJMoa054408, 17182989.
13. Milsom JW, Smith DL, Corman ML, Howerton RA, Yellin AE, Luke DR. Doubleblind comparison of single-dose alatrofloxacin and cefotetan as prophylaxis of infection following elective colorectal surgery. Am J Surg 1998, 176(6A):46S-52S.
14. Mohri Y, Tonouchi H, Kobayashi M, Nakai K, Kusunoki M, Mie Surgical Infection Research Group Randomized clinical trial of single versus multiple-dose antimicrobial prophylaxis in gastric cancer surgery. Br J Surg 2007, 94:683-688. 10.1002/bjs.5837, 17514671, Mie Surgical Infection Research Group.
15. Fujita S, Saito N, Yamada T, Takii Y, Kondo K, Ohue M, Ikeda E, Moriya Y. Randomized, multicenter trial of antibiotic prophylaxis in elective colorectal surgery: single dose vs 3 doses of a second-generation cephalosporin without metronidazole and oral antibiotics. Arch Surg 2007, 142:657-661. 10.1001/archsurg.142.7.657, 17638804.
16. Yates CC, Whaley D, Babu R, Zhang J, Krishna P, Beckman E, Pasculle AW, Wells A. The effect of multifunctional polymer-based gels on wound healing in full thickness bacteria-contaminated mouse skin wound models. Biomaterials 2007, 28:3977-3986. 10.1016/j.biomaterials.2007.05.008, 2034502, 17561250.
17. Caruso DM, Foster KN, Hermans MH, Rick C. Aquacel Ag in the management of partial-thickness burns: results of a clinical trial. J Burn Care Rehabil 2004, 25:89-97. 10.1097/01.BCR.0000107202.85453.63, 14726745.
18. Caruso DM, Foster KN, Blome-Eberwein SA, Twomey JA, Herndon DN, Luterman A, Silverstein P, Antimarino JR, Bauer GJ. Randomized clinical study of Hydrofiber dressing with silver or silver sulfadiazine in the management of partial-thickness burns. J Burn Care Rehabil 2006, 27(3):298-309.
19. Mishra A, Whitaker IS, Potokar TS, Dickson WA. The use of Aquacel Ag in the treatment of partial thickness burns: a national study. Burns 2007, 33:679-680. 10.1016/j.burns.2006.10.400, 17512668.
20. Paddock HN, Fabia R, Giles S, Hayes J, Lowell W, Adams D, Besner GE. A silver-impregnated antimicrobial dressing reduces hospital costs for pediatric burn patients. J Pediatr Surg 2007, 42:211-213. 10.1016/j.jpedsurg.2006.09.053, 17208568.
21. Saba SC, Tsai R, Glat P. Clinical evaluation comparing the efficacy of aquacel ag hydrofiber dressing versus petrolatum gauze with antibiotic ointment in partial-thickness burns in a pediatric burn center. J Burn Care Rehabil 2009, 30:380-385.
22. Jurczak F, Dugre T, Johnstone A, Offori T, Vujovic Z, Hollander D, AQUACEL Ag Surgical/Trauma Wound Study Group Randomised clinical trial of Hydrofiber dressing with silver versus povidone-iodine gauze in the management of open surgical and traumatic wounds. Int Wound J 2007, 4:66-76. 10.1111/j.1742-481X.2006.00276.x, 17425549, AQUACEL Ag Surgical/Trauma Wound Study Group.
23. Lohsiriwat V, Chuangsuwanich A. Comparison of the ionic silver containing hydrofiber and paraffin gauze dressing on split-thickness skin graft donor sites. Ann Plast Surg 2009, 62:421-422. 10.1097/SAP.0b013e31818a65e9, 19325350.
24. Uchiyama K, Takifuji K, Tani M, Ueno M, Kawai M, Ozawa S, Yamaue H. Prevention of postoperative infections by administration of antimicrobial agents immediately before surgery for patients with gastrointestinal cancers. Hepatogastroenterology 2007, 54:1487-1493.
25. Greif R, Akça O, Horn EP, Kurz A, Sessler DI, Outcomes Research Group Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. N Engl J Med 2000, 342:161-167. 10.1056/NEJM200001203420303, 10639541, Outcomes Research Group.
26. Arnaud JP, Bellissant E, Boissel P, Carlet J, Chastang C, Lafaix C, Rio Y, Berganeschi R. Single-dose amoxycillin-clavulanic acid vs. cefotetan for prophylaxis in elective colorectal surgery: a multicentre, prospective, randomized study. J Hosp Infect 1992, 22:A23-A32.
27. Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999: hospital infection control practices advisory committee. Infect Control Hosp Epidemiol 1999, 20:250-278. 10.1086/501620, 10219875.
28. Tanner J, Woodings D, Moncaster K. Preoperative hair removal to reduce surgical site infection. Cochrane Database Syst Rev 2006, 2:CD004122.
29. Denton GW. Chlorhexidine. Disinfection, Sterilization, and Preservation 2001, 321-336. Lippincott Williams & Wilkins, Philadelphia, Block SS, 5.
30. Baik SH, Gincherman M, Mutch MG, Birnbaum EH, Fleshman JW. Laparoscopic vs open resection for patients with rectal cancer: comparison of perioperative outcomes and long-term survival. Dis Colon Rectum 2011, 54:6-14. 10.1007/DCR.0b013e3181fd19d0, 21160307.
31. Luca F, Cenciarelli S, Valvo M, Pozzi S, Faso FL, Ravizza D, Zampino G, Sonzogni A, Biffi R. Full robotic left colon and rectal cancer resection: technique and early outcome. Ann Surg Oncol 2009, 16:1274-1278. 10.1245/s10434-009-0366-z, 19242762.
32. Pigazzi A, Luca F, Patriti A, Valvo M, Ceccarelli G, Casciola L, Biffi R, Garcia-Aguilar J, Baek JH. Multicentric study on robotic tumor-specific mesorectal excision for the treatment of rectal cancer. Ann Surg Oncol 2010, 17:1614-1620. 10.1245/s10434-010-0909-3, 20087780.